Ceftolozane–tazobactam versus meropenem for treatment of nosocomial pneumonia (ASPECT-NP): a randomised, controlled, double-blind, phase 3, non-inferiority trial
Kollef, Marin H, Nováček, Martin, Kivistik, Ülo, Réa-Neto, Álvaro, Shime, Nobuaki, Martin-Loeches, Ignacio, Timsit, Jean-François, Wunderink, Richard G, Bruno, Christopher J, Huntington, Jennifer A, Lin, Gina, Yu, Brian, Butterton, Joan R, Rhee, Elizabeth G
Published in The Lancet infectious diseases (01.12.2019)
Published in The Lancet infectious diseases (01.12.2019)
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Ceftolozane/tazobactam probability of target attainment and outcomes in participants with augmented renal clearance from the randomized phase 3 ASPECT-NP trial
Shorr, Andrew F, Bruno, Christopher J, Zhang, Zufei, Jensen, Erin, Gao, Wei, Feng, Hwa-Ping, Huntington, Jennifer A, Yu, Brian, Rhee, Elizabeth G, De Anda, Carisa, Basu, Sumit, Kollef, Marin H
Published in Critical care (London, England) (02.10.2021)
Published in Critical care (London, England) (02.10.2021)
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Ceftolozane/tazobactam versus meropenem in patients with ventilated hospital-acquired bacterial pneumonia: subset analysis of the ASPECT-NP randomized, controlled phase 3 trial
Timsit, Jean-François, Huntington, Jennifer A, Wunderink, Richard G, Shime, Nobuaki, Kollef, Marin H, Kivistik, Ülo, Nováček, Martin, Réa-Neto, Álvaro, Martin-Loeches, Ignacio, Yu, Brian, Jensen, Erin H, Butterton, Joan R, Wolf, Dominik J, Rhee, Elizabeth G, Bruno, Christopher J
Published in Critical care (London, England) (11.08.2021)
Published in Critical care (London, England) (11.08.2021)
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Pharmacokinetics and safety of posaconazole intravenous solution and powder for oral suspension in children with neutropenia: an open-label, sequential dose-escalation trial
Groll, Andreas H., Abdel-Azim, Hisham, Lehrnbecher, Thomas, Steinbach, William J., Paschke, Amanda, Mangin, Eric, Winchell, Gregory A., Waskin, Hetty, Bruno, Christopher J.
Published in International journal of antimicrobial agents (01.09.2020)
Published in International journal of antimicrobial agents (01.09.2020)
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Outcomes in participants with failure of initial antibacterial therapy for hospital-acquired/ventilator-associated bacterial pneumonia prior to enrollment in the randomized, controlled phase 3 ASPECT-NP trial of ceftolozane/tazobactam versus meropenem
Kollef, Marin H, Timsit, Jean-François, Martin-Loeches, Ignacio, Wunderink, Richard G, Huntington, Jennifer A, Jensen, Erin H, Yu, Brian, Bruno, Christopher J
Published in Critical care (London, England) (01.12.2022)
Published in Critical care (London, England) (01.12.2022)
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Safety and Efficacy of Ceftolozane/Tazobactam Versus Meropenem in Neonates and Children With Complicated Urinary Tract Infection, Including Pyelonephritis: A Phase 2, Randomized Clinical Trial
Roilides, Emmanuel, Ashouri, Negar, Bradley, John S, Johnson, Matthew G, Lonchar, Julia, Su, Feng-Hsiu, Huntington, Jennifer A, Popejoy, Myra W, Bensaci, Mekki, De Anda, Carisa, Rhee, Elizabeth G, Bruno, Christopher J
Published in The Pediatric infectious disease journal (01.04.2023)
Published in The Pediatric infectious disease journal (01.04.2023)
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Estimation of Absolute and Relative Body Fat Content Using Noninvasive Surrogates: Can DXA Be Bypassed?
Greenblatt, David J, Bruno, Christopher D, Harmatz, Jerold S, Dawson-Hughes, Bess, Zhang, Qingchen, Li, Chunhui, Chow, Christina R
Published in Journal of clinical pharmacology (01.11.2023)
Published in Journal of clinical pharmacology (01.11.2023)
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Progressive multifocal leukoencephalopathy genetic risk variants for pharmacovigilance of immunosuppressant therapies
Hatchwell, Eli, Smith, 3rd, Edward B, Jalilzadeh, Shapour, Bruno, Christopher D, Taoufik, Yassine, Hendel-Chavez, Houria, Liblau, Roland, Brassat, David, Martin-Blondel, Guillaume, Wiendl, Heinz, Schwab, Nicholas, Cortese, Irene, Monaco, Maria Chiara, Imberti, Luisa, Capra, Ruggero, Oksenberg, Jorge R, Gasnault, Jacques, Stankoff, Bruno, Richmond, Todd A, Rancour, David M, Koralnik, Igor J, Hanson, Barbara A, Major, Eugene O, Chow, Christina R, Eis, Peggy S
Published in Frontiers in neurology (14.12.2022)
Published in Frontiers in neurology (14.12.2022)
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A phase III, multicenter, double-blind, randomized clinical trial to evaluate the efficacy and safety of ceftolozane/tazobactam plus metronidazole versus meropenem in Chinese participants with complicated intra-abdominal infections
Sun, Yihong, Fan, Jia, Chen, Gang, Chen, Xiaofei, Du, Xiaoling, Wang, Ye, Wang, Hui, Sun, Fang, Johnson, Matthew G., Bensaci, Mekki, Huntington, Jennifer A., Bruno, Christopher J.
Published in International journal of infectious diseases (01.10.2022)
Published in International journal of infectious diseases (01.10.2022)
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Ceftolozane/tazobactam for hospital-acquired/ventilator-associated bacterial pneumonia due to ESBL-producing Enterobacterales: a subgroup analysis of the ASPECT-NP clinical trial
Paterson, David L, Bassetti, Matteo, Motyl, Mary, Johnson, Matthew G, Castanheira, Mariana, Jensen, Erin H, Huntington, Jennifer A, Yu, Brian, Wolf, Dominik J, Bruno, Christopher J
Published in Journal of antimicrobial chemotherapy (25.08.2022)
Published in Journal of antimicrobial chemotherapy (25.08.2022)
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Population Pharmacokinetic Analysis for Plasma and Epithelial Lining Fluid Ceftolozane/Tazobactam Concentrations in Patients With Ventilated Nosocomial Pneumonia
Zhang, Zufei, Patel, Yogesh T., Fiedler‐Kelly, Jill, Feng, Hwa‐Ping, Bruno, Christopher J., Gao, Wei
Published in Journal of clinical pharmacology (01.02.2021)
Published in Journal of clinical pharmacology (01.02.2021)
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Impact of Obesity on Brexpiprazole Pharmacokinetics: Proposal for Improved Initiation of Treatment
Bruno, Christopher D, Elmokadem, Ahmed, Housand, Conrad, Jordie, Eric Burroughs, Chow, Christina R, Laughren, Thomas P, Greenblatt, David J
Published in Journal of clinical pharmacology (01.01.2022)
Published in Journal of clinical pharmacology (01.01.2022)
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Safety and Efficacy of Ceftolozane/Tazobactam Plus Metronidazole Versus Meropenem From a Phase 2, Randomized Clinical Trial in Pediatric Participants With Complicated Intra-abdominal Infection
Jackson, Carl-Christian A, Newland, Jason, Dementieva, Nataliia, Lonchar, Julia, Su, Feng-Hsiu, Huntington, Jennifer A, Bensaci, Mekki, Popejoy, Myra W, Johnson, Matthew G, De Anda, Carisa, Rhee, Elizabeth G, Bruno, Christopher J
Published in The Pediatric infectious disease journal (01.07.2023)
Published in The Pediatric infectious disease journal (01.07.2023)
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Brexpiprazole Pharmacokinetics in CYP2D6 Poor Metabolizers: Using Physiologically Based Pharmacokinetic Modeling to Optimize Time to Effective Concentrations
Elmokadem, Ahmed, Bruno, Christopher D, Housand, Conrad, Jordie, Eric Burroughs, Chow, Christina R, Lesko, Lawrence J, Greenblatt, David J
Published in Journal of clinical pharmacology (01.01.2022)
Published in Journal of clinical pharmacology (01.01.2022)
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Exposure-Efficacy Analyses Support Optimal Dosing Regimens of Ceftolozane/Tazobactam in Participants with Hospital-Acquired/Ventilator-Associated Bacterial Pneumonia in ASPECT-NP
Gao, Wei, Passarell, Julie, Patel, Yogesh T, Zhang, Zufei, Lin, Gina, Fiedler-Kelly, Jill, Bruno, Christopher J, Rhee, Elizabeth G, De Anda, Carisa S, Feng, Hwa-Ping
Published in Antimicrobial agents and chemotherapy (17.05.2022)
Published in Antimicrobial agents and chemotherapy (17.05.2022)
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Ceftolozane/Tazobactam Probability of Target Attainment in Patients With Hospital‐Acquired or Ventilator‐Associated Bacterial Pneumonia
Gao, Wei, Patel, Yogesh T., Zhang, Zufei, Johnson, Matthew G., Fiedler‐Kelly, Jill, Bruno, Christopher J., Rhee, Elizabeth G., Anda, Carisa De, Feng, Hwa‐Ping
Published in Journal of clinical pharmacology (01.03.2023)
Published in Journal of clinical pharmacology (01.03.2023)
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