Sequential Administration of XPO1 and ATR Inhibitors Enhances Therapeutic Response in TP53-mutated Colorectal Cancer
Inoue, Akira, Robinson, Frederick S., Minelli, Rosalba, Tomihara, Hideo, Rizi, Bahar Salimian, Rose, Johnathon L., Kodama, Takahiro, Srinivasan, Sanjana, Harris, Angela L., Zuniga, Andy M., Mullinax, Robert A., Ma, Xiaoyan, Seth, Sahil, Daniele, Joseph R., Peoples, Michael D., Loponte, Sara, Akdemir, Kadir C., Khor, Tin Oo, Feng, Ningping, Roszik, Jason, Sobieski, Mary M., Brunell, David, Stephan, Clifford, Giuliani, Virginia, Deem, Angela K., Shingu, Takashi, Deribe, Yonathan Lissanu, Menter, David G., Heffernan, Timothy P., Viale, Andrea, Bristow, Christopher A., Kopetz, Scott, Draetta, Giulio F., Genovese, Giannicola, Carugo, Alessandro
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2021)
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Comprehensive pharmacogenomic profiling of human papillomavirus-positive and -negative squamous cell carcinoma identifies sensitivity to aurora kinase inhibition in KMT2D mutants
Kalu, Nene N., Mazumdar, Tuhina, Peng, Shaohua, Tong, Pan, Shen, Li, Wang, Jing, Banerjee, Upasana, Myers, Jeffrey N., Pickering, Curtis R., Brunell, David, Stephan, Clifford C., Johnson, Faye M.
Published in Cancer letters (01.09.2018)
Published in Cancer letters (01.09.2018)
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Journal Article
Studies on the Metabolism and Biological Activity of the Epimers of Sulindac
BRUNELL, David, SAGHER, Daphna, KESARAJU, Shailaja, BROT, Nathan, WEISSBACH, Herbert
Published in Drug metabolism and disposition (01.06.2011)
Published in Drug metabolism and disposition (01.06.2011)
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Journal Article
Apoptotic Gene Expression in Sinecatechins-Treated External Genital and Perianal Warts
Nguyen, Harrison P., Doan, Hung Q., Brunell, David J., Rady, Peter, Tyring, Stephen K.
Published in Viral immunology (01.12.2014)
Published in Viral immunology (01.12.2014)
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Apoptotic gene expression profile in Sinecatechin-treated external and genital warts
Doan, Hung Q, Nguyen, Harrison P, Brunell, David J, Rady, Peter L, Tyring, Stephen K
Published in Journal of dermatological science (01.10.2016)
Published in Journal of dermatological science (01.10.2016)
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Journal Article
Driver network as a biomarker: systematic integration and network modeling of multi-omics data to derive driver signaling pathways for drug combination prediction
Huang, Lei, Brunell, David, Stephan, Clifford, Mancuso, James, Yu, Xiaohui, He, Bin, Thompson, Timothy C, Zinner, Ralph, Kim, Jeri, Davies, Peter, Wong, Stephen T C
Published in Bioinformatics (01.10.2019)
Published in Bioinformatics (01.10.2019)
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Abstract B20: Unbiased high-throughput screenings to identify combination therapies targeting RAS-mutated colorectal cancer
Powell, Reid, Fan, Fan, Sobieski, Mary, Brunell, David, Wang, Rui, Ye, Xiangcang, Stephan, Clifford, Ellis, Lee M., Bhattacharya, Rajat
Published in Molecular cancer research (01.05.2020)
Published in Molecular cancer research (01.05.2020)
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High-throughput screening against protein:protein interaction interfaces reveals anti-cancer therapeutics as potent modulators of the voltage-gated Na + channel complex
Wadsworth, Paul A, Folorunso, Oluwarotimi, Nguyen, Nghi, Singh, Aditya K, D'Amico, Daniela, Powell, Reid T, Brunell, David, Allen, John, Stephan, Clifford, Laezza, Fernanda
Published in Scientific reports (15.11.2019)
Published in Scientific reports (15.11.2019)
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Abstract 4646: Pharmacogenomic screen identifies KMT2D mutations as a biomarker of sensitivity to Aurora kinase inhibition in head and neck and cervical squamous cell carcinoma
Mazumdar, Tuhina, Kalu, Nene N., Peng, Shaohua, Tong, Pan, Shen, Li, Wang, Jing, Myers, Jeffrey N., Pickering, Curtis R., Brunell, David, Stephan, Clifford C., Johnson, Faye M.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Abstract 4669: Overcoming therapy resistance in stem cell-rich triple negative breast cancer through p38 MAP kinase inhibition
Hollander, Petra den, Shah, Shruti, Zhou, Xinhui, Redwood, Abena, Cai, Shi-Rong, Sobieski, Mary, Brunell, David, Stephan, Clifford, Davies, Peter, Piwnica-Worms, Helen, Moulder, Stacy, Symmans, W Fraser, Mani, Sendurai A.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract 4819: High-throughput screening of glioma stem-like cells (GSCs) identifies synergistic therapeutic combination of FGFR inhibitor and CDK4/6 inhibitor
Dong, Jianwen, Martinez-Ledesma, Emmanuel, Nguyen, Nghi, Wu, Shaofang, Piao, Yuji, Tiao, Ningyi, Park, Soon Young, Brunell, David, Stephan, Clifford, Verhaak, Roel, Sulman, Erik, Balasubramaniyan, Veerakumar, Groot, John F. de
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
The polo-like kinase 1 inhibitor volasertib synergistically increases radiation efficacy in glioma stem cells
Dong, Jianwen, Park, Soon Young, Nguyen, Nghi, Ezhilarasan, Ravesanker, Martinez-Ledesma, Emmanuel, Wu, Shaofang, Henry, Verlene, Piao, Yuji, Tiao, Ningyi, Brunell, David, Stephan, Clifford, Verhaak, Roel, Sulman, Erik, Balasubramaniyan, Veerakumar, de Groot, John F
Published in Oncotarget (13.02.2018)
Published in Oncotarget (13.02.2018)
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Xenotransplantation of pediatric low grade gliomas confirms the enrichment of BRAF V600E mutation and preservation of CDKN2A deletion in a novel orthotopic xenograft mouse model of progressive pleomorphic xanthoastrocytoma
Kogiso, Mari, Qi, Lin, Lindsay, Holly, Huang, Yulun, Zhao, Xiumei, Liu, Zhigang, Braun, Frank K, Du, Yuchen, Zhang, Huiyuan, Bae, Goeun, Zhao, Sibo, Injac, Sarah G, Sobieski, Mary, Brunell, David, Mehta, Vidya, Tran, Diep, Murray, Jeffrey, Baxter, Patricia A, Yuan, Xiao-Jun, Su, Jack M, Adesina, Adekunle, Perlaky, Laszlo, Chintagumpala, Murali, Parsons, D Williams, Lau, Ching C, Stephan, Clifford C, Lu, Xinyan, Li, Xiao-Nan
Published in Oncotarget (20.10.2017)
Published in Oncotarget (20.10.2017)
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