Characterization of a novel ATP‐sensitive K+ channel opener, A‐251179, on urinary bladder relaxation and cystometric parameters
Shieh, C‐C, Brune, M E, Buckner, S A, Whiteaker, K L, Molinari, E J, Milicic, I A, Fabiyi, A C, Daza, A, Brioni, J D, Carroll, W A, Matsushita, K, Yamada, M, Kurachi, Y, Gopalakrishnan, M
Published in British journal of pharmacology (01.06.2007)
Published in British journal of pharmacology (01.06.2007)
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In vivo evaluation of the potency and bladder‐vascular selectivity of the ATP‐sensitive potassium channel openers (–)‐cromakalim, ZD6169 and WAY‐133537 in rats
Fabiyi, A.C., Gopalakrishnan, M., Lynch, J.J., Brioni, J.D., Coghlan, M.J., Brune, M.E.
Published in BJU international (01.02.2003)
Published in BJU international (01.02.2003)
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A redesigned Escherichia coli triosephosphate isomerase restores growth properties in a bacterial strain useful for Immobilized Metal Affinity Chromatography (IMAC)
Haley, R., Fruchtl, M., Brune, E.M., Ataai, M., Henry, R., Beitle, R.
Published in Journal of biotechnology (20.10.2014)
Published in Journal of biotechnology (20.10.2014)
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Preclinical pharmacological actions of (+/-)-(1'R,3R)-3-phenyl-1- [1',2',3',4'-tetrahydro-5',6'-methylene-dioxy-1'-naphthalenyl) methyl] pyrrolidine methanesulfonate (ABT-200), a potential antidepressant agent that antagonizes alpha-2 adrenergic receptors and inhibits the neuronal uptake of norepinephrine
Hancock, A A, Buckner, S A, Giardina, W J, Brune, M E, Lee, J Y, Morse, P A, Oheim, K W, Stanisic, D S, Warner, R B, Kerkman, D J
Published in The Journal of pharmacology and experimental therapeutics (01.03.1995)
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Published in The Journal of pharmacology and experimental therapeutics (01.03.1995)
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Characterization of antihypertensive activity of ABBOTT-81988, a nonpeptide angiotensin II antagonist in the renal hypertensive rat
JANG YUN LEE, BUCKNER, S. A, BRUNE, M. E, WARNER, R. B, WINN, M, BISWANATH DE, ZYDOWSKY, T. M, OPGENORTH, T. J, KERKMAN, D. J, DEBERNARDIS, J. F
Published in The Journal of pharmacology and experimental therapeutics (01.01.1994)
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Published in The Journal of pharmacology and experimental therapeutics (01.01.1994)
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Antiobesity evaluation of histamine H3 receptor (H3R) antagonist analogs of A-331440 with improved safety and efficacy
Hancock, A A, Diehl, M S, Fey, T A, Bush, E N, Faghih, R, Miller, T R, Krueger, K M, Pratt, J K, Cowart, M D, Dickinson, R W, Shapiro, R, Knourek-Segel, V E, Droz, B A, McDowell, C A, Krishna, G, Brune, M E, Esbenshade, T A, Jacobson, P B
Published in Inflammation research (01.04.2005)
Published in Inflammation research (01.04.2005)
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2-(Alkylamino)nicotinic acid and analogs. Potent angiotensin II antagonists
Winn, Martin, De, Biswanath, Zydowsky, Thomas M, Altenbach, Robert J, Basha, Fatima Z, Boyd, Steven A, Brune, Michael E, Buckner, Steven A, Crowell, DeAnne
Published in Journal of medicinal chemistry (03.09.1993)
Published in Journal of medicinal chemistry (03.09.1993)
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Antihypertensive activity of ABBOTT-81282, a nonpeptide angiotensin II antagonist, in the renal hypertensive rat
Lee, J Y, Brune, M E, Warner, R B, Buckner, S B, Winn, M, De, B, Zydowsky, T M, Opgenorth, T J, Kerkman, D J, DeBernardis, J F
Published in Pharmacology (01.09.1993)
Published in Pharmacology (01.09.1993)
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Distinctions and contradistinctions between antiobesity histamine H3 receptor (H3R) antagonists compared to cognition-enhancing H3 receptor antagonists
Esbenshade, T. A., Hancock, A. A., Bitner, R. S., Krueger, K. M., Otte, S., Nikkel, A. L., Fey, T. A., Bush, E. N., Dickinson, R. W., Shapiro, R., Knourek-Segel, V., Droz, B. A., Brune, M. E., Jacobson, P. B., Cowart, M. D.
Published in Inflammation research (01.04.2006)
Published in Inflammation research (01.04.2006)
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Cardiovascular effects of orally administered ABBOTT-81988, an angiotensin II antagonist, in conscious spontaneously hypertensive rats
Lee, J Y, Warner, R B, Brune, M E, Adler, A L, Winn, M, De, B, Zydowsky, T M, Opgenorth, T J, Kerkman, D J, DeBernardis, J F
Published in American journal of hypertension (01.11.1994)
Published in American journal of hypertension (01.11.1994)
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Structure-activity studies for a novel series of tricyclic substituted hexahydrobenz[e]isoindole alpha(1A) adrenoceptor antagonists as potential agents for the symptomatic treatment of benign prostatic hyperplasia (BPH)
Meyer, MD, Altenbach, RJ, Basha, FZ, Carroll, WA, Condon, S, Elmore, SW, Kerwin, JF, Sippy, KB, Tietje, K, Wendt, MD, Hancock, AA, Brune, ME, Buckner, SA, Drizin
Published in Journal of medicinal chemistry (20.04.2000)
Published in Journal of medicinal chemistry (20.04.2000)
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Comparison of alpha 1-adrenoceptor agonists in canine urethral pressure profilometry and abdominal leak point pressure models
Brune, M E, O'Neill, A B, Gauvin, D M, Katwala, S P, Altenbach, R J, Brioni, J D, Hancock, A A, Sullivan, J P
Published in The Journal of urology (01.10.2001)
Published in The Journal of urology (01.10.2001)
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Actions of A-131701, a novel, selective antagonist for alpha-1A compared with alpha-1B adrenoceptors on intraurethral and blood pressure responses in conscious dogs and a pharmacodynamic assessment of in vivo prostatic selectivity
Hancock, A A, Brune, M E, Witte, D G, Marsh, K C, Katwala, S, Milicic, I, Ireland, L M, Crowell, D, Meyer, M D, Kerwin, Jr, J F
Published in The Journal of pharmacology and experimental therapeutics (01.05.1998)
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Published in The Journal of pharmacology and experimental therapeutics (01.05.1998)
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Synthesis and pharmacological characterization of 3-[2-((3aR,9bR)-cis-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benz[e]isoindol-2-yl)ethyl]pyrido-[3',4':4,5]thieno[3,2-d]pyrimidine-2,4(1H,3H)-dione (A-131701): A uroselective alpha(1A) adrenoceptor antagonist for the symptomatic treatment of benign prostatic hyperplasia
Meyer, MD, Altenbach, RJ, Basha, FZ, Carroll, WA, Drizin, Elmore, SW, Ehrlich, PP, Lebold, SA, Tietje, K, Sippy, KB, Wendt, MD, Plata, DJ, Plagge, F, Buckner, SA, Brune, ME, Hancock, AA, Kerwin, JF
Published in Journal of medicinal chemistry (26.09.1997)
Published in Journal of medicinal chemistry (26.09.1997)
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Pharmacologic characterization of CHIR 2279, an N-substituted glycine peptoid with high-affinity binding for alpha 1-adrenoceptors
J A Gibbons, A A Hancock, C R Vitt, S Knepper, S A Buckner, M E Brune, I Milicic, J F Kerwin, Jr, L S Richter, E W Taylor, K L Spear, R N Zuckermann, D C Spellmeyer, R A Braeckman, W H Moos
Published in The Journal of pharmacology and experimental therapeutics (01.05.1996)
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Published in The Journal of pharmacology and experimental therapeutics (01.05.1996)
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Relationships between Pharmacokinetics and Blockade of Agonist-Induced Prostatic Intraurethral Pressure and Mean Arterial Pressure in the Conscious Dog After Single and Repeated Daily Oral Administration of Terazosin
Witte, D G, Brune, M E, Katwala, S P, Milicic, I, Kerwin, Jr, J F, Hancock, A A
Published in The Journal of pharmacology and experimental therapeutics (01.08.1997)
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Published in The Journal of pharmacology and experimental therapeutics (01.08.1997)
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Effects of selective and nonselective alpha-1-adrenoceptor antagonists on intraurethral and arterial pressures in intact conscious dogs
Brune, M E, Katwala, S P, Milicic, I, Buckner, S A, Ireland, L M, Kerwin, Jr, J F, Hancock, A A
Published in Pharmacology (01.12.1996)
Published in Pharmacology (01.12.1996)
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