Synthesis and biological activity of peptidyl aldehyde urokinase inhibitors
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Published in Bioorganic & medicinal chemistry letters (01.05.2000)
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Possible intermediate in the tungsten-catalyzed olefin metathesis reaction
Grubbs, Robert H, Brunck, Terence K
Published in Journal of the American Chemical Society (01.04.1972)
Published in Journal of the American Chemical Society (01.04.1972)
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Structurally Homologous Ligand Binding of Integrin Mac-1 and Viral Glycoprotein C Receptors
Altieri, Dario C., Etingin, Orli R., Fair, Daryl S., Brunck, Terence K., Geltosky, John E., Hajjar, David P., Edgington, Thomas S.
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Published in Science (American Association for the Advancement of Science) (22.11.1991)
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Synthesis and biological activity of P2–P4 azapeptidomimetic P1-argininal and P1-ketoargininamide derivatives: a novel class of serine protease inhibitors
Semple, J.Edward, Rowley, David C., Brunck, Terence K., Ripka, William C.
Published in Bioorganic & medicinal chemistry letters (04.02.1997)
Published in Bioorganic & medicinal chemistry letters (04.02.1997)
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Synthesis and biological activity of P 2–P 4 azapeptidomimetic P 1-argininal and P 1-ketoargininamide derivatives: a novel class of serine protease inhibitors
Semple, J.Edward, Rowley, David C., Brunck, Terence K., Ripka, William C.
Published in Bioorganic & medicinal chemistry letters (04.02.1997)
Published in Bioorganic & medicinal chemistry letters (04.02.1997)
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Rational design, synthesis, and serine protease inhibitory activity of a novel P1-argininal derivative featuring a conformationally constrained P2-P3 bicyclic lactam moiety
TAMURA, S. Y, GOLDMAN, E. A, BRUNCK, T. K, RIPKA, W. C, SEMPLE, J. E
Published in Bioorganic & medicinal chemistry letters (04.02.1997)
Published in Bioorganic & medicinal chemistry letters (04.02.1997)
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Design, Synthesis, and Evolution of a Novel, Selective, and Orally Bioavailable Class of Thrombin Inhibitors: P1-Argininal Derivatives Incorporating P3-P4 Lactam Sulfonamide Moieties
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Published in Journal of medicinal chemistry (08.11.1996)
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Rational design and synthesis of a novel, selective class of thrombin inhibitors: P1-argininal derivatives incorporating P3P4 quaternary lactam dipeptide surrogates
Semple, J.Edward, Minami, Nathaniel K., Tamura, Susan Y., Brunck, Terence K., Nutt, Ruth F., Ripka, William C.
Published in Bioorganic & medicinal chemistry letters (23.09.1997)
Published in Bioorganic & medicinal chemistry letters (23.09.1997)
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Rational design, synthesis, and serine protease inhibitory activity of a novel P 1-argininal derivative featuring a conformationally constrained P 2–P 3 bicyclic lactam moiety
Tamura, Susan Y., Goldman, Erick A., Brunck, Terence K., Ripka, William C., Edward Semple, J.
Published in Bioorganic & medicinal chemistry letters (04.02.1997)
Published in Bioorganic & medicinal chemistry letters (04.02.1997)
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Investigation of the S 3 site of thrombin: Design, synthesis and biological activity of 4-substituted 3-amino-2-pyridones incorporating P 1-argininals
Reiner, John E., Lim-Wilby, Margeurita S., Brunck, Terence K., Ha-Uong, Theresa, Goldman, Erick A., Abelman, Matthew A., Nutt, Ruth F., Semple, J.Edward, Tamura, Susan Y.
Published in Bioorganic & medicinal chemistry letters (22.03.1999)
Published in Bioorganic & medicinal chemistry letters (22.03.1999)
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Potent and selective thrombin inhibitors featuring hydrophobic, basic P 3P 4-aminoalkyllactam moieties
Semple, J.Edward, Rowley, David C., Owens, Timothy D., Minami, Nathaniel K., Uong, Theresa H., Brunck, Terence K.
Published in Bioorganic & medicinal chemistry letters (15.12.1998)
Published in Bioorganic & medicinal chemistry letters (15.12.1998)
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Investigation of the S3 site of thrombin : Design, synthesis and biological activity of 4-substituted 3-amino-2-pyridones incorporating P1-ARGININALS
REINER, J. E, LIM-WILBY, M. S, BRUNCK, T. K, HA-UONG, T, GOLDMAN, E. A, ABELMAN, M. A, NUTT, R. F, SEMPLE, J. E, TAMURA, S. Y
Published in Bioorganic & medicinal chemistry letters (22.03.1999)
Published in Bioorganic & medicinal chemistry letters (22.03.1999)
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Synthesis, structure, and structure‐activity relationships of divalent thrombin inhibitors containing an α‐keto‐amide transition‐state mimetic
Krishnan, Raman, Tulinsky, A., Vlasuk, George P., Pearson, Daniel, Vallar, Pureza, Bergum, Peter, Brunck, Terence K., Ripka, William C.
Published in Protein science (01.03.1996)
Published in Protein science (01.03.1996)
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Rational design and synthesis of a novel, selective class of thrombin inhibitors: P 1-argininal derivatives incorporating P 3P 4 quaternary lactam dipeptide surrogates
Semple, J.Edward, Minami, Nathaniel K., Tamura, Susan Y., Brunck, Terence K., Nutt, Ruth F., Ripka, William C.
Published in Bioorganic & medicinal chemistry letters (23.09.1997)
Published in Bioorganic & medicinal chemistry letters (23.09.1997)
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Design and synthesis of a novel class of thrombin inhibitors incorporating heterocyclic dipeptide surrogates
Tamura, Susan Y., Edward Semple, J., Reiner, John E., Goldman, Erick A., Brunck, Terence K., Lim-Wilby, Marguerita S., Carpenter, Stephen H., Rote, William E., Oldeshulte, Gerard L., Richard, Brigitte M., Nutt, Ruth F., Ripka, William C.
Published in Bioorganic & medicinal chemistry letters (17.06.1997)
Published in Bioorganic & medicinal chemistry letters (17.06.1997)
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