The presence of CpGs in AAV gene therapy vectors induces a plasmacytoid dendritic cell-like population very early after administration
Glenn, Justin D., Negash, Henos, Henry, William, Qian, Randolph, Liu, Ye, Danos, Olivier, Bruder, Joseph T., Karumuthil-Melethil, Subha
Published in Cellular immunology (01.05.2024)
Published in Cellular immunology (01.05.2024)
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Sexually dimorphic patterns in electroencephalography power spectrum and autism-related behaviors in a rat model of fragile X syndrome
Wong, Hayes, Hooper, Alexander W.M., Niibori, Yosuke, Lee, Shiron J., Hategan, Luca A., Zhang, Liang, Karumuthil-Melethil, Subha, Till, Sally M., Kind, Peter C., Danos, Olivier, Bruder, Joseph T., Hampson, David R.
Published in Neurobiology of disease (01.12.2020)
Published in Neurobiology of disease (01.12.2020)
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DNA prime/Adenovirus boost malaria vaccine encoding P. falciparum CSP and AMA1 induces sterile protection associated with cell-mediated immunity
Chuang, Ilin, Sedegah, Martha, Cicatelli, Susan, Spring, Michele, Polhemus, Mark, Tamminga, Cindy, Patterson, Noelle, Guerrero, Melanie, Bennett, Jason W, McGrath, Shannon, Ganeshan, Harini, Belmonte, Maria, Farooq, Fouzia, Abot, Esteban, Banania, Jo Glenna, Huang, Jun, Newcomer, Rhonda, Rein, Lisa, Litilit, Dianne, Richie, Nancy O, Wood, Chloe, Murphy, Jittawadee, Sauerwein, Robert, Hermsen, Cornelus C, McCoy, Andrea J, Kamau, Edwin, Cummings, James, Komisar, Jack, Sutamihardja, Awalludin, Shi, Meng, Epstein, Judith E, Maiolatesi, Santina, Tosh, Donna, Limbach, Keith, Angov, Evelina, Bergmann-Leitner, Elke, Bruder, Joseph T, Doolan, Denise L, King, C Richter, Carucci, Daniel, Dutta, Sheetij, Soisson, Lorraine, Diggs, Carter, Hollingdale, Michael R, Ockenhouse, Christian F, Richie, Thomas L
Published in PloS one (14.02.2013)
Published in PloS one (14.02.2013)
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Sex Difference Leads to Differential Gene Expression Patterns and Therapeutic Efficacy in Mucopolysaccharidosis IVA Murine Model Receiving AAV8 Gene Therapy
Piechnik, Matthew, Amendum, Paige C, Sawamoto, Kazuki, Stapleton, Molly, Khan, Shaukat, Fnu, Nidhi, Álvarez, Victor, Pachon, Angelica Maria Herreño, Danos, Olivier, Bruder, Joseph T, Karumuthil-Melethil, Subha, Tomatsu, Shunji
Published in International journal of molecular sciences (21.10.2022)
Published in International journal of molecular sciences (21.10.2022)
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A glycolipid adjuvant, 7DW8-5, enhances CD8+ T cell responses induced by an adenovirus-vectored malaria vaccine in non-human primates
Padte, Neal N, Boente-Carrera, Mar, Andrews, Chasity D, McManus, Jenny, Grasperge, Brooke F, Gettie, Agegnehu, Coelho-dos-Reis, Jordana G, Li, Xiangming, Wu, Douglass, Bruder, Joseph T, Sedegah, Martha, Patterson, Noelle, Richie, Thomas L, Wong, Chi-Huey, Ho, David D, Vasan, Sandhya, Tsuji, Moriya
Published in PloS one (25.10.2013)
Published in PloS one (25.10.2013)
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Modification of Ad5 hexon hypervariable regions circumvents pre-existing Ad5 neutralizing antibodies and induces protective immune responses
Bruder, Joseph T, Semenova, Elena, Chen, Ping, Limbach, Keith, Patterson, Noelle B, Stefaniak, Maureen E, Konovalova, Svetlana, Thomas, Charlie, Hamilton, Melissa, King, C Richter, Richie, Thomas L, Doolan, Denise L
Published in PloS one (05.04.2012)
Published in PloS one (05.04.2012)
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Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors
Hollidge, Bradley S., Carroll, Hayley B., Qian, Randolph, Fuller, Madison L., Giles, April R., Mercer, Andrew C., Danos, Olivier, Liu, Ye, Bruder, Joseph T., Smith, Jared B.
Published in Frontiers in neurology (14.11.2022)
Published in Frontiers in neurology (14.11.2022)
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Gene therapy using an ortholog of human fragile X mental retardation protein partially rescues behavioral abnormalities and EEG activity
Hooper, Alexander W.M., Wong, Hayes, Niibori, Yosuke, Abdoli, Rozita, Karumuthil-Melethil, Subha, Qiao, Chunping, Danos, Olivier, Bruder, Joseph T., Hampson, David R.
Published in Molecular therapy. Methods & clinical development (10.09.2021)
Published in Molecular therapy. Methods & clinical development (10.09.2021)
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Sterile protection against Plasmodium knowlesi in rhesus monkeys from a malaria vaccine: comparison of heterologous prime boost strategies
Jiang, George, Shi, Meng, Conteh, Solomon, Richie, Nancy, Banania, Glenna, Geneshan, Harini, Valencia, Anais, Singh, Priti, Aguiar, Joao, Limbach, Keith, Kamrud, Kurt I, Rayner, Jonathan, Smith, Jonathan, Bruder, Joseph T, King, C Richter, Tsuboi, Takafumi, Takeo, Satoru, Endo, Yaeta, Doolan, Denise L, Richie, Thomas L, Weiss, Walter R
Published in PloS one (10.08.2009)
Published in PloS one (10.08.2009)
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Adenovirus-5-vectored P. falciparum vaccine expressing CSP and AMA1. Part B: safety, immunogenicity and protective efficacy of the CSP component
Tamminga, Cindy, Sedegah, Martha, Regis, David, Chuang, Ilin, Epstein, Judith E, Spring, Michele, Mendoza-Silveiras, Jose, McGrath, Shannon, Maiolatesi, Santina, Reyes, Sharina, Steinbeiss, Victoria, Fedders, Charlotte, Smith, Kathryn, House, Brent, Ganeshan, Harini, Lejano, Jennylynn, Abot, Esteban, Banania, Glenna J, Sayo, Renato, Farooq, Fouzia, Belmonte, Maria, Murphy, Jittawadee, Komisar, Jack, Williams, Jackie, Shi, Meng, Brambilla, Donald, Manohar, Nalini, Richie, Nancy O, Wood, Chloe, Limbach, Keith, Patterson, Noelle B, Bruder, Joseph T, Doolan, Denise L, King, C Richter, Diggs, Carter, Soisson, Lorraine, Carucci, Daniel, Levine, Gail, Dutta, Sheetij, Hollingdale, Michael R, Ockenhouse, Christian F, Richie, Thomas L
Published in PloS one (07.10.2011)
Published in PloS one (07.10.2011)
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New gorilla adenovirus vaccine vectors induce potent immune responses and protection in a mouse malaria model
Limbach, Keith, Stefaniak, Maureen, Chen, Ping, Patterson, Noelle B, Liao, Grant, Weng, Shaojie, Krepkiy, Svetlana, Ekberg, Greg, Torano, Holly, Ettyreddy, Damodar, Gowda, Kalpana, Sonawane, Sharvari, Belmonte, Arnel, Abot, Esteban, Sedegah, Martha, Hollingdale, Michael R, Moormann, Ann, Vulule, John, Villasante, Eileen, Richie, Thomas L, Brough, Douglas E, Bruder, Joseph T
Published in Malaria journal (03.07.2017)
Published in Malaria journal (03.07.2017)
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Adenoviruses isolated from wild gorillas are closely related to human species C viruses
Duncan, McVey, Cranfield, Michael R, Torano, Holly, Kuete, Hubert M, Lee, Grace P, Glenn, Andrew, Bruder, Joseph T, Rangel, David, Brough, Douglas E, Gall, Jason G
Published in Virology (New York, N.Y.) (01.09.2013)
Published in Virology (New York, N.Y.) (01.09.2013)
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Identification of a Suppressor Mutation That Improves the Yields of Hexon-Modified Adenovirus Vectors
Bruder, Joseph T, Chen, Ping, Semenova, Elena, Thomas, Charlie A, Konovalova, Svetlana, Ekberg, Greg, Ettyreddy, Damodar, McVey, Duncan, Gall, Jason G, King, C Richter, Brough, Douglas E
Published in Journal of Virology (01.09.2013)
Published in Journal of Virology (01.09.2013)
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Identification and localization of minimal MHC-restricted CD8+ T cell epitopes within the Plasmodium falciparum AMA1 protein
Sedegah, Martha, Kim, Yohan, Peters, Bjoern, McGrath, Shannon, Ganeshan, Harini, Lejano, Jennylynn, Abot, Esteban, Banania, Glenna, Belmonte, Maria, Sayo, Renato, Farooq, Fouzia, Doolan, Denise L, Regis, David, Tamminga, Cindy, Chuang, Ilin, Bruder, Joseph T, King, C Richter, Ockenhouse, Christian F, Faber, Bart, Remarque, Edmond, Hollingdale, Michael R, Richie, Thomas L, Sette, Alessandro
Published in Malaria journal (24.08.2010)
Published in Malaria journal (24.08.2010)
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Liver-Targeted AAV8 Gene Therapy Ameliorates Skeletal and Cardiovascular Pathology in a Mucopolysaccharidosis IVA Murine Model
Sawamoto, Kazuki, Karumuthil-Melethil, Subha, Khan, Shaukat, Stapleton, Molly, Bruder, Joseph T., Danos, Olivier, Tomatsu, Shunji
Published in Molecular therapy. Methods & clinical development (11.09.2020)
Published in Molecular therapy. Methods & clinical development (11.09.2020)
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Epitopes Expressed in Different Adenovirus Capsid Proteins Induce Different Levels of Epitope-Specific Immunity
KRAUSE, Anja, JOH, Ju H, HACKETT, Neil R, ROELVINK, Peter W, BRUDER, Joseph T, WICKHAM, Thomas J, KOVESDI, Imre, CRYSTAL, Ronald G, WORGALL, Stefan
Published in Journal of Virology (01.06.2006)
Published in Journal of Virology (01.06.2006)
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Promoters influence the kinetics of transgene expression following adenovector gene delivery
Chen, Ping, Tian, Jie, Kovesdi, Imre, Bruder, Joseph T.
Published in The journal of gene medicine (01.02.2008)
Published in The journal of gene medicine (01.02.2008)
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Journal Article
Adenovectors induce functional antibodies capable of potent inhibition of blood stage malaria parasite growth
Bruder, Joseph T, Stefaniak, Maureen E, Patterson, Noelle B, Chen, Ping, Konovalova, Svetlana, Limbach, Keith, Campo, Joseph J, Ettyreddy, Damodar, Li, Sheng, Dubovsky, Filip, Richie, Thomas L, King, C. Richter, Long, Carole A, Doolan, Denise L
Published in Vaccine (19.04.2010)
Published in Vaccine (19.04.2010)
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Profiling the Targets of Protective CD8 + T Cell Responses to Infection
Bruder, Joseph T, Chen, Ping, Ekberg, Greg, Smith, Emily C, Lazarski, Christopher A, Myers, Bennett A, Bolton, Jessica, Sedegah, Martha, Villasante, Eileen, Richie, Thomas L, King, C Richter, Aguiar, Joao C, Doolan, Denise L, Brough, Douglas E
Published in Molecular therapy. Methods & clinical development (15.12.2017)
Published in Molecular therapy. Methods & clinical development (15.12.2017)
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