Search Results - "BRUCE FREIMARK" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Phosphatidylserine Sensing by TAM Receptors Regulates AKT-Dependent Chemoresistance and PD-L1 Expression

Phosphatidylserine Sensing by TAM Receptors Regulates AKT-Dependent Chemoresistance and PD-L1 Expression

by Kasikara, Canan, Kumar, Sushil, Kimani, Stanley, Tsou, Wen-I, Geng, Ke, Davra, Viralkumar, Sriram, Ganapathy, Devoe, Connor, Nguyen, Khanh-Quynh N, Antes, Anita, Krantz, Allen, Rymarczyk, Grzegorz, Wilczynski, Andrzej, Empig, Cyril, Freimark, Bruce, Gray, Michael, Schlunegger, Kyle, Hutchins, Jeff, Kotenko, Sergei V, Birge, Raymond B
Published in Molecular cancer research (01.06.2017)

Get full text

Journal Article

Antibody targeting of phosphatidylserine for the detection and immunotherapy of cancer

Antibody targeting of phosphatidylserine for the detection and immunotherapy of cancer

by Belzile, Olivier, Huang, Xianming, Gong, Jian, Carlson, Jay, Schroit, Alan J, Brekken, Rolf A, Freimark, Bruce D
Published in ImmunoTargets and therapy (01.01.2018)

Get full text

Journal Article

Phosphatidylserine-targeting antibodies augment the anti-tumorigenic activity of anti-PD-1 therapy by enhancing immune activation and downregulating pro-oncogenic factors induced by T-cell checkpoint inhibition in murine triple-negative breast cancers

Phosphatidylserine-targeting antibodies augment the anti-tumorigenic activity of anti-PD-1 therapy by enhancing immune activation and downregulating pro-oncogenic factors induced by T-cell checkpoint inhibition in murine triple-negative breast cancers

by Gray, Michael J, Gong, Jian, Hatch, Michaela M S, Nguyen, Van, Hughes, Christopher C W, Hutchins, Jeff T, Freimark, Bruce D
Published in Breast cancer research : BCR (11.05.2016)

Get full text

Journal Article

Nano-pulse stimulation™ therapy (NPS™) is superior to cryoablation in clearing murine melanoma tumors

Nano-pulse stimulation™ therapy (NPS™) is superior to cryoablation in clearing murine melanoma tumors

by McDaniel, Amanda, Freimark, Bruce, Navarro, Cebrina, Von Rothstein, Kristin, Gonzalez, Dacia, Linder, Keith, Nuccitelli, Richard
Published in Frontiers in oncology (08.02.2023)

Get full text

Journal Article

First-in-Man Evaluation of 124I-PGN650: A PET Tracer for Detecting Phosphatidylserine as a Biomarker of the Solid Tumor Microenvironment

First-in-Man Evaluation of 124I-PGN650: A PET Tracer for Detecting Phosphatidylserine as a Biomarker of the Solid Tumor Microenvironment

by Laforest, Richard, Dehdashti, Farrokh, Liu, Yongjian, Frye, Jennifer, Frye, Sarah, Luehmann, Hannah, Sultan, Deborah, Shan, Joseph S., Freimark, Bruce D., Siegel, Barry A.
Published in Molecular imaging (16.10.2017)

Get full text

Journal Article

Antibody-Mediated Phosphatidylserine Blockade Enhances the Antitumor Responses to CTLA-4 and PD-1 Antibodies in Melanoma

Antibody-Mediated Phosphatidylserine Blockade Enhances the Antitumor Responses to CTLA-4 and PD-1 Antibodies in Melanoma

by Freimark, Bruce D, Gong, Jian, Ye, Dan, Gray, Michael J, Nguyen, Van, Yin, Shen, Hatch, Michaela M S, Hughes, Christopher C W, Schroit, Alan J, Hutchins, Jeff T, Brekken, Rolf A, Huang, Xianming
Published in Cancer immunology research (01.06.2016)

Get more information

Journal Article

First-in-Man Evaluation of 124 I-PGN650: A PET Tracer for Detecting Phosphatidylserine as a Biomarker of the Solid Tumor Microenvironment

First-in-Man Evaluation of 124 I-PGN650: A PET Tracer for Detecting Phosphatidylserine as a Biomarker of the Solid Tumor Microenvironment

by Laforest, Richard, Dehdashti, Farrokh, Liu, Yongjian, Frye, Jennifer, Frye, Sarah, Luehmann, Hannah, Sultan, Deborah, Shan, Joseph S, Freimark, Bruce D, Siegel, Barry A
Published in Molecular imaging (01.01.2017)

Get full text

Journal Article

Measuring Response to Therapy by Near-Infrared Imaging of Tumors Using a Phosphatidylserine-Targeting Antibody Fragment

Measuring Response to Therapy by Near-Infrared Imaging of Tumors Using a Phosphatidylserine-Targeting Antibody Fragment

by Gong, Jian, Archer, Richard, Brown, Michael, Fisher, Seth, Chang, Connie, Peacock, Matthew, Hughes, Christopher, Freimark, Bruce
Published in Molecular imaging (01.06.2013)

Get full text

Journal Article

Cationic Lipids Enhance Cytokine and Cell Influx Levels in the Lung Following Administration of Plasmid: Cationic Lipid Complexes

Cationic Lipids Enhance Cytokine and Cell Influx Levels in the Lung Following Administration of Plasmid: Cationic Lipid Complexes

by Freimark, Bruce D, Blezinger, H. Paul, Florack, Valarie J, Nordstrom, Jeffrey L, Long, Scott D, Deshpande, Deepa S, Nochumson, Sam, Petrak, Karel L
Published in The Journal of immunology (1950) (01.05.1998)

Get full text

Journal Article

First-in-Man Evaluation of I-PGN650: A PET Tracer for Detecting Phosphatidylserine as a Biomarker of the Solid Tumor Microenvironment

First-in-Man Evaluation of I-PGN650: A PET Tracer for Detecting Phosphatidylserine as a Biomarker of the Solid Tumor Microenvironment

by Richard Laforest PhD, Farrokh Dehdashti MD, Yongjian Liu PhD, Jennifer Frye CMMT, Sarah Frye CMMT, Hannah Luehmann, Deborah Sultan, Joseph S. Shan PhD, Bruce D. Freimark PhD, Barry A. Siegel MD
Published in Molecular imaging (09.10.2017)

Get full text

Journal Article

Anti-Tumor Responses By Ibrutinib and Anti-PD-1 Blockade Is Enhanced By Phosphatidylserine-Targeting Antibody Therapy

Anti-Tumor Responses By Ibrutinib and Anti-PD-1 Blockade Is Enhanced By Phosphatidylserine-Targeting Antibody Therapy

by Gong, Jian, Gray, Michael, Hutchins, Jeff, Freimark, Bruce
Published in Blood (02.12.2016)

Get full text

Journal Article

Formation, clearance, deposition, pathogenicity, and identification of biopharmaceutical-related immune complexes: review and case studies

Formation, clearance, deposition, pathogenicity, and identification of biopharmaceutical-related immune complexes: review and case studies

by Rojko, Jennifer L, Evans, Mark G, Price, Shari A, Han, Bora, Waine, Gary, DeWitte, Mark, Haynes, Jill, Freimark, Bruce, Martin, Pauline, Raymond, James T, Evering, Winston, Rebelatto, Marlon C, Schenck, Emanuel, Horvath, Christopher
Published in Toxicologic pathology (01.06.2014)

Get more information

Journal Article

Abstract 3657: Phosphatidylserine-targeting antibodies enhance anti-tumor activity of a tumor vaccine in a HPV-induced tumor model

Abstract 3657: Phosphatidylserine-targeting antibodies enhance anti-tumor activity of a tumor vaccine in a HPV-induced tumor model

by Weir, Genevieve, Quinton, Tara, Hutchins, Jeff T., Freimark, Bruce D., Stanford, Marianne
Published in Cancer research (Chicago, Ill.) (01.07.2017)

Get full text

Journal Article

Abstract 3652: Combinational activity of LAG3 and PD-1 targeted therapies is significantly enhanced by the addition of phosphatidylserine targeting antibodies and establishes an anti-tumor memory response in murine triple negative breast cancer

Abstract 3652: Combinational activity of LAG3 and PD-1 targeted therapies is significantly enhanced by the addition of phosphatidylserine targeting antibodies and establishes an anti-tumor memory response in murine triple negative breast cancer

by Gray, Michael J., Gong, Jian, Hutchins, Jeff T., Freimark, Bruce D.
Published in Cancer research (Chicago, Ill.) (01.07.2017)

Get full text

Journal Article

Rapid vascular regrowth in tumors after reversal of VEGF inhibition

Rapid vascular regrowth in tumors after reversal of VEGF inhibition

by Mancuso, Michael R, Davis, Rachel, Norberg, Scott M, O'Brien, Shaun, Sennino, Barbara, Nakahara, Tsutomu, Yao, Virginia J, Inai, Tetsuichiro, Brooks, Peter, Freimark, Bruce, Shalinsky, David R, Hu-Lowe, Dana D, McDonald, Donald M
Published in The Journal of clinical investigation (01.10.2006)

Get full text

Journal Article

Abstract 4289: Targeting of phosphatidylserine by monoclonal antibodies enhances the activity of immune checkpoint inhibitors in breast tumors

Abstract 4289: Targeting of phosphatidylserine by monoclonal antibodies enhances the activity of immune checkpoint inhibitors in breast tumors

by Gong, Jian, Yin, Shen, Nguyen, Van, Hutchins, Jeff, Freimark, Bruce D.
Published in Cancer research (Chicago, Ill.) (01.08.2015)

Get full text

Journal Article

Abstract PR09: Antibody-mediated blockade of phosphatidylserine synergizes with immune checkpoint blockade by inhibiting multiple immune suppressive mechanisms

Abstract PR09: Antibody-mediated blockade of phosphatidylserine synergizes with immune checkpoint blockade by inhibiting multiple immune suppressive mechanisms

by Huang, Xianming, Gong, Jian, Gray, Michael, Nguyen, Van, Parks, Ryan, Hughes, Chris, Hutchins, Jeff, Brekken, Rolf, Freimark, Bruce
Published in Cancer research (Chicago, Ill.) (01.08.2016)

Get full text

Journal Article

Abstract P5-04-12: Targeting of phosphatidylserine by monoclonal antibodies enhances activity of immune checkpoint inhibitors in breast tumors

Abstract P5-04-12: Targeting of phosphatidylserine by monoclonal antibodies enhances activity of immune checkpoint inhibitors in breast tumors

by Freimark, Bruce, Gong, Jian, Nguyen, Van, Yin, Shen, Archer, Rich, Hutchins, Jeff
Published in Cancer research (Chicago, Ill.) (01.05.2015)

Get full text

Journal Article

Abstract 1651: Targeting phosphatidylserine in combination with adoptive T cell transfer eliminates advanced tumors without off-target toxicities in a melanoma preclinical model

Abstract 1651: Targeting phosphatidylserine in combination with adoptive T cell transfer eliminates advanced tumors without off-target toxicities in a melanoma preclinical model

by Hirschhorn-Cymerman, Daniel, Schad, Sara Sara, Budhu, Sadna, Hong, Zhong, Yang, Xia, Jeff, Hutchins T., Freimark, Bruce D., Gray, Michael J., Wolchok, Jedd, Merghoub, Taha
Published in Cancer research (Chicago, Ill.) (01.07.2017)

Get full text

Journal Article

Abstract 574: Phosphatidylserine targeting antibody in combination with tumor radiation and immune checkpoint blockade promotes anti-tumor activity in mouse B16 melanoma

Abstract 574: Phosphatidylserine targeting antibody in combination with tumor radiation and immune checkpoint blockade promotes anti-tumor activity in mouse B16 melanoma

by Budhu, Sadna, Henau, Olivier De, Zappasodi, Roberta, Giese, Rachel, Campesato, Luis F., Barker, Christopher, Freimark, Bruce, Hutchins, Jeff, Wolchok, Jedd D., Merghoub, Taha
Published in Cancer research (Chicago, Ill.) (01.07.2017)

Get full text

Journal Article