Pharmacogenomics and chemical library screens reveal a novel SCF SKP2 inhibitor that overcomes Bortezomib resistance in multiple myeloma
Malek, E, Abdel-Malek, M A Y, Jagannathan, S, Vad, N, Karns, R, Jegga, A G, Broyl, A, van Duin, M, Sonneveld, P, Cottini, F, Anderson, K C, Driscoll, J J
Published in Leukemia (01.03.2017)
Published in Leukemia (01.03.2017)
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Pharmacogenomics and chemical library screens reveal a novel SCFSKP2 inhibitor that overcomes Bortezomib resistance in multiple myeloma
Malek, E, Abdel-Malek, M A Y, Jagannathan, S, Vad, N, Karns, R, Jegga, A G, Broyl, A, van Duin, M, Sonneveld, P, Cottini, F, Anderson, K C, Driscoll, J J
Published in Leukemia (01.03.2017)
Published in Leukemia (01.03.2017)
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A gene expression signature for high-risk multiple myeloma
KUIPER, R, BROYL, A, GOLDSCHMIDT, H, LOKHORST, H. M, DUIN, M. Van, SONNEVELD, P, DE KNEGT, Y, VLIET, Mh Van, BEERS, Eh Van, DER HOLT, B. Van, EL JARARI, L, MULLIGAN, G, GREGORY, W, MORGAN, G
Published in Leukemia (01.11.2012)
Published in Leukemia (01.11.2012)
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Gene expression profile alone is inadequate in predicting complete response in multiple myeloma
Amin, S B, Yip, W-K, Minvielle, S, Broyl, A, Li, Y, Hanlon, B, Swanson, D, Shah, P K, Moreau, P, van der Holt, B, van Duin, M, Magrangeas, F, Pieter Sonneveld, P, Anderson, K C, Li, C, Avet-Loiseau, H, Munshi, N C
Published in Leukemia (01.11.2014)
Published in Leukemia (01.11.2014)
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MicroRNA signatures characterize multiple myeloma patients
CORTHALS, S. L, SUN, S. M, ZWEEGMAN, S, JONGEN-LAVRENCIC, M, SONNEVELD, P, KUIPER, R, DE KNEGT, Y, BROYL, A, VAN DER HOLT, B, BEVERLOO, H. B, PEETERS, J. K, EL JARARI, L, LOKHORST, H. M
Published in Leukemia (01.11.2011)
Published in Leukemia (01.11.2011)
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Ixazomib-Thalidomide-Low Dose Dexamethasone (ITd) Induction Followed By Maintenance Therapy with Ixazomib or Placebo in Newly Diagnosed Multiple Myeloma Patients Not Eligible for Autologous Stem Cell Transplantation; Initial Results from the Randomized Phase II HOVON-126/Nmsg 21.13 Trial
Zweegman, Sonja, van der Holt, Bronno, Schjesvold, Fredrik H., Levin, Mark-David, Stege, Claudia A.M., Waage, Anders, Leijs, Maria Berhardina, Klein, Saskia, Szatkowski, Damian L., Broyl, A, Axelsson, Per, Hieu Do, Trung, Knut-Bojanovska, Dorota, van der Spek, Ellen, Svirskaite, Asta, Cunha, Sonia, Hansson, Markus, Sonneveld, Pieter, Haukaas, Einar, Abildgaard, Niels
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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B03 CARFILZOMIB AND LENALIDOMIDE FOR PRIMARY PLASMA CELL LEUKEMIA: FINAL RESULTS OF THE PROSPECTIVE PHASE 2 EMN12/HOVON-129 STUDY FOR PATIENTS AGED ≥66 YEARS
Musto, P., Minnema, M.C., Roeloffzen, W.W.H., Capra, A., van der Holt, B., Juul Vangsted, A., Broyl, A., Schjesvold, F., Lund, T., Silkjaer, T., Benjamin, R., Grasso, M., Lung Wu, K., Caers, J., Cavo, M., Hájek, R., Bruno, B., Gadisseur, A., Pietrantuono, G., Offidani, M., Pour, L., Sonneveld, P., Boccadoro, M., van de Donk, N.
Published in HemaSphere (09.05.2023)
Published in HemaSphere (09.05.2023)
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Cancer testis antigens in newly diagnosed and relapse multiple myeloma: prognostic markers and potential targets for immunotherapy
VAN DUIN, Mark, BROYL, Annemiek, SAHOTA, Surinder S, SONNEVELD, Pieter, DE KNEGT, Yvonne, GOLDSCHMIDT, Hartmut, RICHARDSON, Paul G, HOP, Wim C. J, VAN DER HOLT, Bronno, JOSEPH-PIETRAS, Debora, MULLIGAN, George, NEUWIRTH, Rachel
Published in Haematologica (Roma) (01.11.2011)
Published in Haematologica (Roma) (01.11.2011)
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B02 CARFILZOMIB AND LENALIDOMIDE‐BASED THERAPY FOR THE TREATMENT OF PRIMARY PLASMA CELL LEUKEMIA: RESULTS OF THE FINAL ANALYSIS OF THE PROSPECTIVE PHASE 2 EMN12/HOVON‐129 STUDY FOR PATIENTS AGED 18‐65 YEARS
Donk, N., Minnema, M.C., Holt, B., Schjesvold, F., Wu, K.L., Capra, A., Broyl, A., Roeloffzen, W.W.H., Gadisseur, A.P.A., Pietrantuono, G., Pour, L., Velden, V., Lund, T., Offidani, M., Grasso, M., Giaccone, L., Cavo, M., Silkjaer, T., Caers, J., Zweegman, S., Hajek, R., Benjamin, R., Vangsted, A., Boccadoro, M., Gay, F., Sonneveld, P., Musto, P.
Published in HemaSphere (09.05.2023)
Published in HemaSphere (09.05.2023)
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A gene expression signature for high-risk multiple myeloma
Kuiper, R, Broyl, A, de Knegt, Y, van Vliet, M H, van Beers, E H, van der Holt, B, el Jarari, L, Mulligan, G, Gregory, W, Morgan, G, Goldschmidt, H, Lokhorst, H M, van Duin, M, Sonneveld, P
Published in Leukemia (01.05.2014)
Published in Leukemia (01.05.2014)
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Assessing the effect of obesity-related traits on multiple myeloma using a Mendelian randomisation approach
Went, M, Sud, A, Law, P J, Johnson, D C, Weinhold, N, Försti, A, van Duin, M, Mitchell, J S, Chen, B, Kuiper, R, Stephens, O W, Bertsch, U, Campo, C, Einsele, H, Gregory, W M, Henrion, M, Hillengass, J, Hoffmann, P, Jackson, G H, Lenive, O, Nickel, J, Nöthen, M M, da Silva Filho, M I, Thomsen, H, Walker, B A, Broyl, A, Davies, F E, Langer, C, Hansson, M, Kaiser, M, Sonneveld, P, Goldschmidt, H, Hemminki, K, Nilsson, B, Morgan, G J, Houlston, R S
Published in Blood cancer journal (New York) (16.06.2017)
Published in Blood cancer journal (New York) (16.06.2017)
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Genome-wide association study identifies multiple susceptibility loci for multiple myeloma
Mitchell, Jonathan S, Li, Ni, Weinhold, Niels, Försti, Asta, Ali, Mina, van Duin, Mark, Thorleifsson, Gudmar, Johnson, David C, Chen, Bowang, Halvarsson, Britt-Marie, Gudbjartsson, Daniel F, Kuiper, Rowan, Stephens, Owen W, Bertsch, Uta, Broderick, Peter, Campo, Chiara, Einsele, Hermann, Gregory, Walter A, Gullberg, Urban, Henrion, Marc, Hillengass, Jens, Hoffmann, Per, Jackson, Graham H, Johnsson, Ellinor, Jöud, Magnus, Kristinsson, Sigurður Y, Lenhoff, Stig, Lenive, Oleg, Mellqvist, Ulf-Henrik, Migliorini, Gabriele, Nahi, Hareth, Nelander, Sven, Nickel, Jolanta, Nöthen, Markus M, Rafnar, Thorunn, Ross, Fiona M, da Silva Filho, Miguel Inacio, Swaminathan, Bhairavi, Thomsen, Hauke, Turesson, Ingemar, Vangsted, Annette, Vogel, Ulla, Waage, Anders, Walker, Brian A, Wihlborg, Anna-Karin, Broyl, Annemiek, Davies, Faith E, Thorsteinsdottir, Unnur, Langer, Christian, Hansson, Markus, Kaiser, Martin, Sonneveld, Pieter, Stefansson, Kari, Morgan, Gareth J, Goldschmidt, Hartmut, Hemminki, Kari, Nilsson, Björn, Houlston, Richard S
Published in Nature communications (01.07.2016)
Published in Nature communications (01.07.2016)
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Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma
Went, Molly, Sud, Amit, Försti, Asta, Halvarsson, Britt-Marie, Weinhold, Niels, Kimber, Scott, van Duin, Mark, Thorleifsson, Gudmar, Holroyd, Amy, Johnson, David C, Li, Ni, Orlando, Giulia, Law, Philip J, Ali, Mina, Chen, Bowang, Mitchell, Jonathan S, Gudbjartsson, Daniel F, Kuiper, Rowan, Stephens, Owen W, Bertsch, Uta, Broderick, Peter, Campo, Chiara, Bandapalli, Obul R, Einsele, Hermann, Gregory, Walter A, Gullberg, Urban, Hillengass, Jens, Hoffmann, Per, Jackson, Graham H, Jöckel, Karl-Heinz, Johnsson, Ellinor, Kristinsson, Sigurður Y, Mellqvist, Ulf-Henrik, Nahi, Hareth, Easton, Douglas, Pharoah, Paul, Dunning, Alison, Peto, Julian, Canzian, Federico, Swerdlow, Anthony, Eeles, Rosalind A, Kote-Jarai, ZSofia, Muir, Kenneth, Pashayan, Nora, Nickel, Jolanta, Nöthen, Markus M, Rafnar, Thorunn, Ross, Fiona M, da Silva Filho, Miguel Inacio, Thomsen, Hauke, Turesson, Ingemar, Vangsted, Annette, Andersen, Niels Frost, Waage, Anders, Walker, Brian A, Wihlborg, Anna-Karin, Broyl, Annemiek, Davies, Faith E, Thorsteinsdottir, Unnur, Langer, Christian, Hansson, Markus, Goldschmidt, Hartmut, Kaiser, Martin, Sonneveld, Pieter, Stefansson, Kari, Morgan, Gareth J, Hemminki, Kari, Nilsson, Björn, Houlston, Richard S
Published in Nature communications (13.09.2018)
Published in Nature communications (13.09.2018)
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Mechanisms of peripheral neuropathy associated with bortezomib and vincristine in patients with newly diagnosed multiple myeloma: a prospective analysis of data from the HOVON-65/GMMG-HD4 trial
Broyl, Annemiek, Dr, Corthals, Sophie L, MSc, Jongen, Joost LM, MD, van der Holt, Bronno, PhD, Kuiper, Rowan, BSc, de Knegt, Yvonne, BSc, van Duin, Mark, PhD, el Jarari, Laila, MSc, Bertsch, Uta, MD, Lokhorst, Henk M, Prof, Durie, Brian G, MD, Goldschmidt, Hartmut, Prof, Sonneveld, Pieter, Prof
Published in The lancet oncology (01.11.2010)
Published in The lancet oncology (01.11.2010)
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Pharmacogenomics and chemical library screens reveal a novel SCF super(SKP2) inhibitor that overcomes Bortezomib resistance in multiple myeloma
Malek, E, Abdel-Malek, M A Y, Jagannathan, S, Vad, N, Karns, R, Jegga, A G, Broyl, A, van Duin, M, Sonneveld, P, Cottini, F, Anderson, K C, Driscoll, J J
Published in Leukemia (01.03.2017)
Published in Leukemia (01.03.2017)
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Higher Expression of Nuclear Cereblon in Bone Marrow Biopsies of Patients with Multiple Myeloma Included in the HOVON-87/Nmsg-18 Trial May be Associated with Longer PFS and OS
Wester, Ruth, Lam, King Hong, van Duin, Mark, Couto, Suzana, Ren, Yan, Wang, Maria, van der Holt, Bronno, Beverloo, Berna, Visser-Wisselaar, Heleen, Nigg, Alex, Qian, Max, Thakurta, Anjan, Broyl, Annemiek, Zweegman, Sonja, Sonneveld, Pieter
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Author Correction: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma
Went, Molly, Sud, Amit, Försti, Asta, Halvarsson, Britt-Marie, Weinhold, Niels, Kimber, Scott, van Duin, Mark, Thorleifsson, Gudmar, Holroyd, Amy, Johnson, David C, Li, Ni, Orlando, Giulia, Law, Philip J, Ali, Mina, Chen, Bowang, Mitchell, Jonathan S, Gudbjartsson, Daniel F, Kuiper, Rowan, Stephens, Owen W, Bertsch, Uta, Broderick, Peter, Campo, Chiara, Bandapalli, Obul R, Einsele, Hermann, Gregory, Walter A, Gullberg, Urban, Hillengass, Jens, Hoffmann, Per, Jackson, Graham H, Jöckel, Karl-Heinz, Johnsson, Ellinor, Kristinsson, Sigurður Y, Mellqvist, Ulf-Henrik, Nahi, Hareth, Easton, Douglas, Pharoah, Paul, Dunning, Alison, Peto, Julian, Canzian, Federico, Swerdlow, Anthony, Eeles, Rosalind A, Kote-Jarai, Zsofia, Muir, Kenneth, Pashayan, Nora, Nickel, Jolanta, Nöthen, Markus M, Rafnar, Thorunn, Ross, Fiona M, da Silva Filho, Miguel Inacio, Thomsen, Hauke, Turesson, Ingemar, Vangsted, Annette, Andersen, Niels Frost, Waage, Anders, Walker, Brian A, Wihlborg, Anna-Karin, Broyl, Annemiek, Davies, Faith E, Thorsteinsdottir, Unnur, Langer, Christian, Hansson, Markus, Goldschmidt, Hartmut, Kaiser, Martin, Sonneveld, Pieter, Stefansson, Kari, Morgan, Gareth J, Hemminki, Kari, Nilsson, Björn, Houlston, Richard S
Published in Nature communications (10.01.2019)
Published in Nature communications (10.01.2019)
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Erratum: A gene expression signature for high-risk multiple myeloma
Kuiper, R, Broyl, A, de Knegt, Y, van Vliet, M H, van Beers, E H, van der Holt, B, el Jarari, L, Mulligan, G, Gregory, W, Morgan, G, Goldschmidt, H, Lokhorst, H M, van Duin, M, Sonneveld, P
Published in Leukemia (07.05.2014)
Published in Leukemia (07.05.2014)
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Gene Expression Profiles for Molecular Classification of Multiple Myeloma in Newly Diagnosed Patients Included in a Prospective, Multicenter, Phase 3 Trial
Broyl, A., Peeters, J., Hose, D., de Knegt, Y., Beverloo, B., Lokhorst, H., Goldschmidt, H., van Duin, M., Sonneveld, P.
Published in Blood (16.11.2008)
Published in Blood (16.11.2008)
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