Identification and optimisation of a novel series of pyrimidine based cyclooxygenase-2 (COX-2) inhibitors. Utilisation of a biotransformation approach
Beswick, Paul J., Blackaby, Andrew P., Bountra, Chas, Brown, Terry, Browning, Kerry, Campbell, Ian B., Corfield, John, Gleave, Robert J., Guntrip, Steve B., Hall, Richard M., Hindley, Sean, Lambeth, Paul F., Lucas, Fiona, Mathews, Neil, Naylor, Alan, Player, Hazel, Price, Helen S., Sidebottom, Phillip J., Taylor, Nicholas L., Webb, Graham, Wiseman, Joanne
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
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Identification of 2,3-diaryl-pyrazolo[1,5-b]pyridazines as potent and selective cyclooxygenase-2 inhibitors
BESWICK, Paul, BINGHAM, Sharon, GUNTRIP, Stephen, HASLAM, Claudine, LAMBETH, Paul, LUCAS, Fiona, MATHEWS, Neil, MURKIT, Graham, NAYLOR, Alan, PEGG, Neil, PICKUP, Elizabeth, PLAYER, Hazel, BOUNTRA, Chas, PRICE, Helen, STEVENS, Alexander, STRATTON, Sharon, WISEMAN, Joanne, BROWN, Terry, BROWNING, Kerry, CAMPBELL, Ian, CHESSELL, Lain, CLAYTON, Nick, COLLINS, Sue, CORFIELD, John
Published in Bioorganic & medicinal chemistry letters (01.11.2004)
Published in Bioorganic & medicinal chemistry letters (01.11.2004)
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