3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration
Wang, Hongbing, Brown, Paul C., Chow, Edwin C.Y., Ewart, Lorna, Ferguson, Stephen S., Fitzpatrick, Suzanne, Freedman, Benjamin S., Guo, Grace L., Hedrich, William, Heyward, Scott, Hickman, James, Isoherranen, Nina, Li, Albert P., Liu, Qi, Mumenthaler, Shannon M., Polli, James, Proctor, William R., Ribeiro, Alexandre, Wang, Jian‐Ying, Wange, Ronald L., Huang, Shiew‐Mei
Published in Clinical and translational science (01.09.2021)
Published in Clinical and translational science (01.09.2021)
Get full text
Journal Article
IVIVE: Facilitating the Use of In Vitro Toxicity Data in Risk Assessment and Decision Making
Chang, Xiaoqing, Tan, Yu-Mei, Allen, David G, Bell, Shannon, Brown, Paul C, Browning, Lauren, Ceger, Patricia, Gearhart, Jeffery, Hakkinen, Pertti J, Kabadi, Shruti V, Kleinstreuer, Nicole C, Lumen, Annie, Matheson, Joanna, Paini, Alicia, Pangburn, Heather A, Petersen, Elijah J, Reinke, Emily N, Ribeiro, Alexandre J S, Sipes, Nisha, Sweeney, Lisa M, Wambaugh, John F, Wange, Ronald, Wetmore, Barbara A, Mumtaz, Moiz
Published in Toxics (Basel) (01.05.2022)
Published in Toxics (Basel) (01.05.2022)
Get full text
Journal Article
Gaps and challenges in nonclinical assessments of pharmaceuticals: An FDA/CDER perspective on considerations for development of new approach methodologies
Avila, Amy M., Bebenek, Ilona, Mendrick, Donna L., Peretz, Jackye, Yao, Jia, Brown, Paul C.
Published in Regulatory toxicology and pharmacology (01.03.2023)
Published in Regulatory toxicology and pharmacology (01.03.2023)
Get full text
Journal Article
An FDA/CDER perspective on nonclinical testing strategies: Classical toxicology approaches and new approach methodologies (NAMs)
Avila, Amy M., Bebenek, Ilona, Bonzo, Jessica A., Bourcier, Todd, Davis Bruno, Karen L., Carlson, David B., Dubinion, John, Elayan, Ikram, Harrouk, Wafa, Lee, Shwu-Luan, Mendrick, Donna L., Merrill, Jill C., Peretz, Jackye, Place, Emily, Saulnier, Muriel, Wange, Ronald L., Yao, Jia, Zhao, Dong, Brown, Paul C.
Published in Regulatory toxicology and pharmacology (01.07.2020)
Published in Regulatory toxicology and pharmacology (01.07.2020)
Get full text
Journal Article
Regulatory Perspectives on Juvenile Animal Toxicologic Pathology
Rao, Deepa B, Hoberman, Alan M, Brown, Paul C, Varela, Aurore, Bolon, Brad
Published in Toxicologic pathology (01.12.2021)
Published in Toxicologic pathology (01.12.2021)
Get more information
Journal Article
Parallel evaluation of alternative skin barrier models and excised human skin for dermal absorption studies in vitro
Salminen, Alec T., Davis, Kelly J., Felton, Robert P., Nischal, Nathania, VonTungeln, Linda S., Beland, Frederick A., Derr, Kristy, Brown, Paul C., Ferrer, Marc, Katz, Linda M., Kleinstreuer, Nicole C., Leshin, Jonathan, Manga, Prashiela, Sadrieh, Nakissa, Xia, Menghang, Fitzpatrick, Suzanne C., Camacho, Luísa
Published in Toxicology in vitro (01.09.2023)
Published in Toxicology in vitro (01.09.2023)
Get full text
Journal Article
Perspectives on the evaluation and adoption of complex in vitro models in drug development: Workshop with the FDA and the pharmaceutical industry (IQ MPS Affiliate)
Baran, Szczepan W, Brown, Paul C, Baudy, Andreas R, Fitzpatrick, Suzanne C, Frantz, Christopher, Fullerton, Aaron, Gan, Jinping, Hardwick, Rhiannon N, Hillgren, Kathleen M, Kopec, Anna K, Liras, Jennifer L, Mendrick, Donna L, Nagao, Ryan, Proctor, William R, Ramsden, Diane, Ribeiro, Alexandre J.S, Stresser, David, Sung, Kyung E, Sura, Radhakrishna, Tetsuka, Kazuhiro, Tomlinson, Lindsay, Van Vleet, Terry, Wagoner, Matthew P, Wang, Qin, Arslan, Sevim Yildiz, Yoder, Gorm, Ekert, Jason E
Published in ALTEX, alternatives to animal experimentation (2022)
Published in ALTEX, alternatives to animal experimentation (2022)
Get full text
Journal Article
CDER photosafety guidance for industry
Jacobs, Abigail C, Brown, Paul C, Chen, Conrad, Ellis, Amy, Farrelly, James, Osterberg, Robert
Published in Toxicologic pathology (01.07.2004)
Published in Toxicologic pathology (01.07.2004)
Get more information
Journal Article
CDER Risk Assessment Exercise to Evaluate Potential Risks from the Use of Nanomaterials in Drug Products
Cruz, Celia N., Tyner, Katherine M., Velazquez, Lydia, Hyams, Kenneth C., Jacobs, Abigail, Shaw, Arthur B., Jiang, Wenlei, Lionberger, Robert, Hinderling, Peter, Kong, Yoon, Brown, Paul C., Ghosh, Tapash, Strasinger, Caroline, Suarez-Sharp, Sandra, Henry, Don, Van Uitert, Maat, Sadrieh, Nakissa, Morefield, Elaine
Published in The AAPS journal (01.07.2013)
Published in The AAPS journal (01.07.2013)
Get full text
Journal Article
Parallel evaluation of alternative skin barrier models and excised human skin for dermal absorption studies in vitro
Salminen, Alec T., Davis, Kelly J., Felton, Robert P., Nischal, Nathania, VonTungeln, Linda S., Beland, Frederick A., Derr, Kristy, Brown, Paul C., Ferrer, Marc, Katz, Linda M., Kleinstreuer, Nicole C., Leshin, Jonathan, Manga, Prashiela, Sadrieh, Nakissa, Xia, Menghang, Fitzpatrick, Suzanne C., Camacho, Luísa
Published in Toxicology in vitro (01.09.2023)
Get full text
Published in Toxicology in vitro (01.09.2023)
Journal Article
Potential value of animal microphysiological systems
Published in ALTEX, alternatives to animal experimentation
(07.08.2024)
Get full text
Journal Article
A Concept Representation Language (CRL)
Brown, Paul C.
Published in 2018 IEEE 12th International Conference on Semantic Computing (ICSC) (01.01.2018)
Published in 2018 IEEE 12th International Conference on Semantic Computing (ICSC) (01.01.2018)
Get full text
Conference Proceeding
CENTRIFUGAL ACCELERATION STABILIZER
Impastato, Charles, Swiatek, Chester V, Brown, Paul C, Grigoriev, Mikhail
Year of Publication 07.03.2024
Get full text
Year of Publication 07.03.2024
Patent