Changes in microbiota composition, bile and fatty acid metabolism, in successful faecal microbiota transplantation for Clostridioides difficile infection
Brown, Jillian R-M, Flemer, Burkhardt, Joyce, Susan A, Zulquernain, Akbar, Sheehan, Donal, Shanahan, Fergus, O'Toole, Paul W
Published in BMC gastroenterology (28.08.2018)
Published in BMC gastroenterology (28.08.2018)
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Prebiotic supplementation in frail older people affects specific gut microbiota taxa but not global diversity
Tran, Tam T T, Cousin, Fabien J, Lynch, Denise B, Menon, Ravi, Brulc, Jennifer, Brown, Jillian R-M, O'Herlihy, Eileen, Butto, Ludovica F, Power, Katie, Jeffery, Ian B, O'Connor, Eibhlís M, O'Toole, Paul W
Published in Microbiome (13.03.2019)
Published in Microbiome (13.03.2019)
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Journal Article
Disease-specific non-reducing end carbohydrate biomarkers for mucopolysaccharidoses
Lawrence, Roger, Brown, Jillian R, Al-Mafraji, Kanar, Lamanna, William C, Beitel, James R, Boons, Geert-Jan, Esko, Jeffrey D, Crawford, Brett E
Published in Nature chemical biology (08.01.2012)
Published in Nature chemical biology (08.01.2012)
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Delivery of an enzyme-IGFII fusion protein to the mouse brain is therapeutic for mucopolysaccharidosis type IIIB
Kan, Shih-hsin, Aoyagi-Scharber, Mika, Le, Steven Q., Vincelette, Jon, Ohmi, Kazuhiro, Bullens, Sherry, Wendt, Daniel J., Christiansen, Terri M., Tiger, Pascale M. N., Brown, Julian R., Lawrence, Roger, Yip, Bryan K., Holtzinger, John, Bagri, Anil, Crippen-Harmon, Danielle, Vondrak, Kristen N., Chen, Zhi, Hague, Chuck M., Woloszynek, Josh C., Cheung, Diana S., Webster, Katherine A., Adintori, Evan G., Lo, Melanie J., Wong, Wesley, Fitzpatrick, Paul A., LeBowitz, Jonathan H., Crawford, Brett E., Bunting, Stuart, Dickson, Patricia I., Neufeld, Elizabeth F.
Published in Proceedings of the National Academy of Sciences - PNAS (14.10.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (14.10.2014)
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Journal Article
Nigral overexpression of α‐synuclein in a rat Parkinson’s disease model indicates alterations in the enteric nervous system and the gut microbiome
O’Donovan, Sarah M., Crowley, Erin K., Brown, Jillian R.‐M., O’Sullivan, Orla, O’Leary, Olivia F., Timmons, Suzanne, Nolan, Yvonne M., Clarke, David J., Hyland, Niall P., Joyce, Susan A., Sullivan, Aideen M., O'Neill, Cora
Published in Neurogastroenterology and motility (01.01.2020)
Published in Neurogastroenterology and motility (01.01.2020)
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Journal Article
Genistein improves neuropathology and corrects behaviour in a mouse model of neurodegenerative metabolic disease
Malinowska, Marcelina, Wilkinson, Fiona L, Langford-Smith, Kia J, Langford-Smith, Alex, Brown, Jillian R, Crawford, Brett E, Vanier, Marie T, Grynkiewicz, Grzegorz, Wynn, Rob F, Wraith, J Ed, Wegrzyn, Grzegorz, Bigger, Brian W
Published in PloS one (01.12.2010)
Published in PloS one (01.12.2010)
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Journal Article
Surfen, a small molecule antagonist of heparan sulfate
Schuksz, Manuela, Fuster, Mark M, Brown, Jillian R, Crawford, Brett E, Ditto, David P, Lawrence, Roger, Glass, Charles A, Wang, Lianchun, Tor, Yitzhak, Esko, Jeffrey D
Published in Proceedings of the National Academy of Sciences - PNAS (02.09.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (02.09.2008)
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Journal Article
Effect of room temperature transport vials on DNA quality and phylogenetic composition of faecal microbiota of elderly adults and infants
Hill, Cian J, Brown, Jillian R M, Lynch, Denise B, Jeffery, Ian B, Ryan, C Anthony, Ross, R Paul, Stanton, Catherine, O'Toole, Paul W
Published in Microbiome (10.05.2016)
Published in Microbiome (10.05.2016)
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Journal Article
Heparan Sulfate 2-O-Sulfotransferase Is Required for Triglyceride-rich Lipoprotein Clearance
Stanford, Kristin I., Wang, Lianchun, Castagnola, Jan, Song, Danyin, Bishop, Joseph R., Brown, Jillian R., Lawrence, Roger, Bai, Xaiomei, Habuchi, Hiroko, Tanaka, Masakazu, Cardoso, Wellington V., Kimata, Koji, Esko, Jeffrey D.
Published in The Journal of biological chemistry (01.01.2010)
Published in The Journal of biological chemistry (01.01.2010)
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Journal Article
Translational studies of intravenous and intracerebroventricular routes of administration for CNS cellular biodistribution for BMN 250, an enzyme replacement therapy for the treatment of Sanfilippo type B
Grover, Anita, Crippen-Harmon, Danielle, Nave, Lacey, Vincelette, Jon, Wait, Jill C. M., Melton, Andrew C., Lawrence, Roger, Brown, Jillian R., Webster, Katherine A., Yip, Bryan K., Baridon, Brian, Vitelli, Catherine, Rigney, Sara, Christianson, Terri M., Tiger, Pascale M. N., Lo, Melanie J., Holtzinger, John, Shaywitz, Adam J., Crawford, Brett E., Fitzpatrick, Paul A., LeBowitz, Jonathan H., Bullens, Sherry, Aoyagi-Scharber, Mika, Bunting, Stuart, O’Neill, Charles A., Pinkstaff, Jason, Bagri, Anil
Published in Drug delivery and translational research (01.04.2020)
Published in Drug delivery and translational research (01.04.2020)
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Journal Article
Enzyme augmentation therapy enhances the therapeutic efficacy of bone marrow transplantation in mucopolysaccharidosis type II mice
Akiyama, Kazumasa, Shimada, Yohta, Higuchi, Takashi, Ohtsu, Makoto, Nakauchi, Hiromitsu, Kobayashi, Hiroshi, Fukuda, Takahiro, Ida, Hiroyuki, Eto, Yoshikatsu, Crawford, Brett E., Brown, Jillian R., Ohashi, Toya
Published in Molecular genetics and metabolism (01.02.2014)
Published in Molecular genetics and metabolism (01.02.2014)
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Journal Article
Specific antibody titer alters the effectiveness of intrathecal enzyme replacement therapy in canine mucopolysaccharidosis I
Dickson, Patricia I., Ellinwood, N. Matthew, Brown, Jillian R., Witt, Robert G., Le, Steven Q., Passage, Merry B., Vera, Moin U., Crawford, Brett E.
Published in Molecular genetics and metabolism (01.05.2012)
Published in Molecular genetics and metabolism (01.05.2012)
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Towards standards for human fecal sample processing in metagenomic studies
Costea, Paul I, Zeller, Georg, Sunagawa, Shinichi, Pelletier, Eric, Alberti, Adriana, Levenez, Florence, Tramontano, Melanie, Driessen, Marja, Hercog, Rajna, Jung, Ferris-Elias, Kultima, Jens Roat, Hayward, Matthew R, Coelho, Luis Pedro, Allen-Vercoe, Emma, Bertrand, Laurie, Blaut, Michael, Brown, Jillian R M, Carton, Thomas, Cools-Portier, Stéphanie, Daigneault, Michelle, Derrien, Muriel, Druesne, Anne, de Vos, Willem M, Finlay, B Brett, Flint, Harry J, Guarner, Francisco, Hattori, Masahira, Heilig, Hans, Luna, Ruth Ann, van Hylckama Vlieg, Johan, Junick, Jana, Klymiuk, Ingeborg, Langella, Philippe, Le Chatelier, Emmanuelle, Mai, Volker, Manichanh, Chaysavanh, Martin, Jennifer C, Mery, Clémentine, Morita, Hidetoshi, O'Toole, Paul W, Orvain, Céline, Patil, Kiran Raosaheb, Penders, John, Persson, Søren, Pons, Nicolas, Popova, Milena, Salonen, Anne, Saulnier, Delphine, Scott, Karen P, Singh, Bhagirath, Slezak, Kathleen, Veiga, Patrick, Versalovic, James, Zhao, Liping, Zoetendal, Erwin G, Ehrlich, S Dusko, Dore, Joel, Bork, Peer
Published in Nature biotechnology (01.11.2017)
Published in Nature biotechnology (01.11.2017)
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Journal Article
A Disaccharide-Based Inhibitor of Glycosylation Attenuates Metastatic Tumor Cell Dissemination
Brown, Jillian R, Fuster, Mark M, Li, Ruixia, Varki, Nissi, Glass, Charles A, Esko, Jeffrey D
Published in Clinical cancer research (01.05.2006)
Published in Clinical cancer research (01.05.2006)
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Journal Article
Resistance to a Bacterial Toxin Is Mediated by Removal of a Conserved Glycosylation Pathway Required for Toxin-Host Interactions
Griffitts, Joel S., Huffman, Danielle L., Whitacre, Johanna L., Barrows, Brad D., Marroquin, Lisa D., Müller, Reto, Brown, Jillian R., Hennet, Thierry, Esko, Jeffrey D., Aroian, Raffi V.
Published in The Journal of biological chemistry (14.11.2003)
Published in The Journal of biological chemistry (14.11.2003)
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Journal Article
Glycan-based biomarkers for mucopolysaccharidoses
Lawrence, Roger, Brown, Jillian R., Lorey, Fred, Dickson, Patricia I., Crawford, Brett E., Esko, Jeffrey D.
Published in Molecular genetics and metabolism (01.02.2014)
Published in Molecular genetics and metabolism (01.02.2014)
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Journal Article
Synthesis and biological evaluation of gem-diamine 1- N-iminosugars related to l-iduronic acid as inhibitors of heparan sulfate 2- O-sulfotransferase
Brown, Jillian R., Nishimura, Yoshio, Esko, Jeffrey D.
Published in Bioorganic & medicinal chemistry letters (01.02.2006)
Published in Bioorganic & medicinal chemistry letters (01.02.2006)
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Journal Article
Evaluation of non-reducing end pathologic glycosaminoglycan detection method for monitoring therapeutic response to enzyme replacement therapy in human mucopolysaccharidosis I
Vera, Moin U., Le, Steven Q., Victoroff, Alla, Passage, Merry B., Brown, Jillian R., Crawford, Brett E., Polgreen, Lynda E., Chen, Agnes H., Dickson, Patricia I.
Published in Molecular genetics and metabolism (01.02.2020)
Published in Molecular genetics and metabolism (01.02.2020)
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