Bioactivity of AAV2-neurturin gene therapy (CERE-120): Differences between Parkinson's disease and nonhuman primate brains
Bartus, Raymond T., Herzog, Christopher D., Chu, Yaping, Wilson, Alistair, Brown, Lamar, Siffert, Joao, Johnson Jr, Eugene M., Olanow, C. Warren, Mufson, Elliott J., Kordower, Jeffrey H.
Published in Movement disorders (01.01.2011)
Published in Movement disorders (01.01.2011)
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Advancing neurotrophic factors as treatments for age-related neurodegenerative diseases: developing and demonstrating “clinical proof-of-concept” for AAV-neurturin (CERE-120) in Parkinson's disease
Bartus, Raymond T, Baumann, Tiffany L, Brown, Lamar, Kruegel, Brian R, Ostrove, Jeffrey M, Herzog, Christopher D
Published in Neurobiology of aging (2013)
Published in Neurobiology of aging (2013)
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Enhanced neurotrophic distribution, cell signaling and neuroprotection following substantia nigral versus striatal delivery of AAV2-NRTN (CERE-120)
Herzog, Christopher D, Brown, Lamar, Kruegel, Brian R, Wilson, Alistair, Tansey, Malú G, Gage, Fred H, Johnson, Eugene M, Bartus, Raymond T
Published in Neurobiology of disease (01.10.2013)
Published in Neurobiology of disease (01.10.2013)
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Properly scaled and targeted AAV2-NRTN (neurturin) to the substantia nigra is safe, effective and causes no weight loss: Support for nigral targeting in Parkinson's disease
Bartus, Raymond T, Brown, Lamar, Wilson, Alistair, Kruegel, Brian, Siffert, Joao, Johnson, Eugene M, Kordower, Jeffrey H, Herzog, Christopher D
Published in Neurobiology of disease (01.10.2011)
Published in Neurobiology of disease (01.10.2011)
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Gene transfer provides a practical means for safe, long-term, targeted delivery of biologically active neurotrophic factor proteins for neurodegenerative diseases
Herzog, Christopher D., Bishop, Kathie M., Brown, Lamar, Wilson, Alistair, Kordower, Jeffrey H., Bartus, Raymond T.
Published in Drug delivery and translational research (01.10.2011)
Published in Drug delivery and translational research (01.10.2011)
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Expression, bioactivity, and safety 1 year after adeno-associated viral vector type 2-mediated delivery of neurturin to the monkey nigrostriatal system support cere-120 for Parkinson's disease
Herzog, Christopher D, Brown, Lamar, Gammon, Dawn, Kruegel, Brian, Lin, Richard, Wilson, Alistair, Bolton, Ariadne, Printz, Marie, Gasmi, Mehdi, Bishop, Kathie M, Kordower, Jeffrey H, Bartus, Raymond T
Published in Neurosurgery (01.04.2009)
Published in Neurosurgery (01.04.2009)
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Advancing neurotrophic factors as treatments for age-related neurodegenerative diseases: developing and demonstrating aclinical proof-of-concepta for AAV-neurturin (CERE-120) in Parkinson's disease
Bartus, Raymond T, Baumann, Tiffany L, Brown, Lamar, Kruegel, Brian R, Ostrove, Jeffrey M, Herzog, Christopher D
Published in Neurobiology of aging (01.01.2013)
Published in Neurobiology of aging (01.01.2013)
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EXPRESSION, BIOACTIVITY, AND SAFETY 1 YEAR AFTER ADENO-ASSOCIATED VIRAL VECTOR TYPE 2-MEDIATED DELIVERY OF NEURTURIN TO THE MONKEY NIGROSTRIATAL SYSTEM SUPPORT CERE-120 FOR PARKINSON'S DISEASE. Commentaries
HERZOG, Christopher D, BROWN, Lamar, KORDOWER, Jeffrey H, BARTUS, Raymond T, FRANZ, Colin K, STARR, Philip A, GAMMON, Dawn, KRUEGEL, Brian, LIN, Richard, WILSON, Alistair, BOLTON, Ariadne, PRINTZ, Marie, GASMI, Mehdi, BISHOP, Kathie M
Published in Neurosurgery (2009)
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Published in Neurosurgery (2009)
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527. CERE-110, an AAV2-Based Vector To Deliver NGF, Provides Trophic Activity to Basal Forebrain Cholinergic Neurons in Rats and Cynomolgous Monkeys
Bishop, Kathie M, Hofer, Katrin, Rius, Denise, Mehta, Arpesh, Lawandry, Shokry, Brown, Lamar, Kruegel, Brian, Gasmi, Mehdi, Tuszynski, Mark, Bartus, Raymond T
Published in Molecular therapy (01.05.2004)
Published in Molecular therapy (01.05.2004)
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