Advances in therapeutic peptides targeting G protein-coupled receptors
Davenport, Anthony P., Scully, Conor C. G., de Graaf, Chris, Brown, Alastair J. H., Maguire, Janet J.
Published in Nature reviews. Drug discovery (01.06.2020)
Published in Nature reviews. Drug discovery (01.06.2020)
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A Lipidomic Analysis of Placenta in Preeclampsia: Evidence for Lipid Storage
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Published in PloS one (29.09.2016)
Published in PloS one (29.09.2016)
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Crystal structure of the GLP-1 receptor bound to a peptide agonist
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Published in Nature (London) (08.06.2017)
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Extra-helical binding site of a glucagon receptor antagonist
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Published in Nature (London) (12.05.2016)
Published in Nature (London) (12.05.2016)
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Acetylcholine prioritises direct synaptic inputs from entorhinal cortex to CA1 by differential modulation of feedforward inhibitory circuits
Palacios-Filardo, Jon, Udakis, Matt, Brown, Giles A., Tehan, Benjamin G., Congreve, Miles S., Nathan, Pradeep J., Brown, Alastair J. H., Mellor, Jack R.
Published in Nature communications (16.09.2021)
Published in Nature communications (16.09.2021)
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Molecular basis for RNA polymerase-dependent transcription complex recycling by the helicase-like motor protein HelD
Newing, Timothy P., Oakley, Aaron J., Miller, Michael, Dawson, Catherine J., Brown, Simon H. J., Bouwer, James C., Tolun, Gökhan, Lewis, Peter J.
Published in Nature communications (18.12.2020)
Published in Nature communications (18.12.2020)
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Structural basis of promiscuous substrate transport by Organic Cation Transporter 1
Zeng, Yi C., Sobti, Meghna, Quinn, Ada, Smith, Nicola J., Brown, Simon H. J., Vandenberg, Jamie I., Ryan, Renae M., O’Mara, Megan L., Stewart, Alastair G.
Published in Nature communications (11.10.2023)
Published in Nature communications (11.10.2023)
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Variation in structural motifs within SARS-related coronavirus spike proteins
Hills, Francesca R, Eruera, Alice-Roza, Hodgkinson-Bean, James, Jorge, Fátima, Easingwood, Richard, Brown, Simon H J, Bouwer, James C, Li, Yi-Ping, Burga, Laura N, Bostina, Mihnea
Published in PLoS pathogens (28.05.2024)
Published in PLoS pathogens (28.05.2024)
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Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients
Rouet, Romain, Henry, Jake Y., Johansen, Matt D., Sobti, Meghna, Balachandran, Harikrishnan, Langley, David B., Walker, Gregory J., Lenthall, Helen, Jackson, Jennifer, Ubiparipovic, Stephanie, Mazigi, Ohan, Schofield, Peter, Burnett, Deborah L., Brown, Simon H. J., Martinello, Marianne, Hudson, Bernard, Gilroy, Nicole, Post, Jeffrey J., Kelleher, Anthony, Jäck, Hans-Martin, Goodnow, Christopher C., Turville, Stuart G., Rawlinson, William D., Bull, Rowena A., Stewart, Alastair G., Hansbro, Philip M., Christ, Daniel
Published in Nature communications (08.02.2023)
Published in Nature communications (08.02.2023)
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Structural characterisation of the complete cycle of sliding clamp loading in Escherichia coli
Xu, Zhi-Qiang, Jergic, Slobodan, Lo, Allen T. Y., Pradhan, Alok C., Brown, Simon H. J., Bouwer, James C., Ghodke, Harshad, Lewis, Peter J., Tolun, Gökhan, Oakley, Aaron J., Dixon, Nicholas E.
Published in Nature communications (27.09.2024)
Published in Nature communications (27.09.2024)
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Cholesteryl ester levels are elevated in the caudate and putamen of Huntington’s disease patients
Phillips, Gabrielle R., Hancock, Sarah E., Brown, Simon H. J., Jenner, Andrew M., Kreilaus, Fabian, Newell, Kelly A., Mitchell, Todd W.
Published in Scientific reports (20.11.2020)
Published in Scientific reports (20.11.2020)
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An Improved High-Throughput Lipid Extraction Method for the Analysis of Human Brain Lipids
Abbott, Sarah K., Jenner, Andrew M., Mitchell, Todd W., Brown, Simon H. J., Halliday, Glenda M., Garner, Brett
Published in Lipids (01.03.2013)
Published in Lipids (01.03.2013)
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Author Correction: Acetylcholine prioritises direct synaptic inputs from entorhinal cortex to CA1 by differential modulation of feedforward inhibitory circuits
Palacios-Filardo, Jon, Udakis, Matt, Brown, Giles A., Tehan, Benjamin G., Congreve, Miles S., Nathan, Pradeep J., Brown, Alastair J. H., Mellor, Jack R.
Published in Nature communications (08.12.2021)
Published in Nature communications (08.12.2021)
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Glucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March to Therapeutic Successes
Graaf, Chris de, Donnelly, Dan, Wootten, Denise, Lau, Jesper, Sexton, Patrick M, Miller, Laurence J, Ahn, Jung-Mo, Liao, Jiayu, Fletcher, Madeleine M, Yang, Dehua, Brown, Alastair J H, Zhou, Caihong, Deng, Jiejie, Wang, Ming-Wei
Published in Pharmacological reviews (01.10.2016)
Published in Pharmacological reviews (01.10.2016)
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