Targeting phospholipase D in cancer, infection and neurodegenerative disorders
Brown, H. Alex, Thomas, Paul G., Lindsley, Craig W.
Published in Nature reviews. Drug discovery (01.05.2017)
Published in Nature reviews. Drug discovery (01.05.2017)
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Journal Article
Phospholipase D signaling pathways and phosphatidic acid as therapeutic targets in cancer
Bruntz, Ronald C, Lindsley, Craig W, Brown, H Alex
Published in Pharmacological reviews (01.10.2014)
Published in Pharmacological reviews (01.10.2014)
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Journal Article
Phospholipase D: Enzymology, Functionality, and Chemical Modulation
Selvy, Paige E, Lavieri, Robert R, Lindsley, Craig W, Brown, H. Alex
Published in Chemical reviews (12.10.2011)
Published in Chemical reviews (12.10.2011)
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Journal Article
Adiponutrin Functions as a Nutritionally Regulated Lysophosphatidic Acid Acyltransferase
Kumari, Manju, Schoiswohl, Gabriele, Chitraju, Chandramohan, Paar, Margret, Cornaciu, Irina, Rangrez, Ashraf Y., Wongsiriroj, Nuttaporn, Nagy, Harald M., Ivanova, Pavlina T., Scott, Sarah A., Knittelfelder, Oskar, Rechberger, Gerald N., Birner-Gruenberger, Ruth, Eder, Sandra, Brown, H. Alex, Haemmerle, Guenter, Oberer, Monika, Lass, Achim, Kershaw, Erin E., Zimmermann, Robert, Zechner, Rudolf
Published in Cell metabolism (02.05.2012)
Published in Cell metabolism (02.05.2012)
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Journal Article
Lenz-Majewski mutations in PTDSS1 affect phosphatidylinositol 4-phosphate metabolism at ER-PM and ER-Golgi junctions
Sohn, Mira, Ivanova, Pavlina, Brown, H. Alex, Toth, Daniel J., Varnai, Peter, Kim, Yeun Ju, Balla, Tamas
Published in Proceedings of the National Academy of Sciences - PNAS (19.04.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (19.04.2016)
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Journal Article
Enhanced synthesis of saturated phospholipids is associated with ER stress and lipotoxicity in palmitate treated hepatic cells[S]
Leamy, Alexandra K., Egnatchik, Robert A., Shiota, Masakazu, Ivanova, Pavlina T., Myers, David S., Brown, H. Alex, Young, Jamey D.
Published in Journal of lipid research (01.07.2014)
Published in Journal of lipid research (01.07.2014)
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Journal Article
Increased diacylglycerols characterize hepatic lipid changes in progression of human nonalcoholic fatty liver disease; comparison to a murine model
Gorden, D Lee, Ivanova, Pavlina T, Myers, David S, McIntyre, J Oliver, VanSaun, Michael N, Wright, J Kelly, Matrisian, Lynn M, Brown, H Alex
Published in PloS one (09.08.2011)
Published in PloS one (09.08.2011)
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Journal Article
Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches
Shakya, Sajina, Gromovsky, Anthony D, Hale, James S, Knudsen, Arnon M, Prager, Briana, Wallace, Lisa C, Penalva, Luiz O F, Brown, H Alex, Kristensen, Bjarne W, Rich, Jeremy N, Lathia, Justin D, Brown, J Mark, Hubert, Christopher G
Published in Acta neuropathologica communications (31.05.2021)
Published in Acta neuropathologica communications (31.05.2021)
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Journal Article
Lipidomics: An analysis of cellular lipids by ESI-MS
Milne, Stephen, Ivanova, Pavlina, Forrester, Jeffrey, Alex Brown, H.
Published in Methods (San Diego, Calif.) (01.06.2006)
Published in Methods (San Diego, Calif.) (01.06.2006)
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Journal Article
Protein Modification by Endogenously Generated Lipid Electrophiles: Mitochondria as the Source and Target
Beavers, William N, Rose, Kristie L, Galligan, James J, Mitchener, Michelle M, Rouzer, Carol A, Tallman, Keri A, Lamberson, Connor R, Wang, Xiaojing, Hill, Salisha, Ivanova, Pavlina T, Brown, H. Alex, Zhang, Bing, Porter, Ned A, Marnett, Lawrence J
Published in ACS chemical biology (18.08.2017)
Published in ACS chemical biology (18.08.2017)
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Journal Article
FAM83B mediates EGFR- and RAS-driven oncogenic transformation
Cipriano, Rocky, Graham, James, Miskimen, Kristy L S, Bryson, Benjamin L, Bruntz, Ronald C, Scott, Sarah A, Brown, H Alex, Stark, George R, Jackson, Mark W
Published in The Journal of clinical investigation (01.09.2012)
Published in The Journal of clinical investigation (01.09.2012)
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Journal Article
Spatial and temporal alterations of phospholipids determined by mass spectrometry during mouse embryo implantation[S]
Burnum, Kristin E., Cornett, Dale S., Puolitaival, Satu M., Milne, Stephen B., Myers, David S., Tranguch, Susanne, Brown, H. Alex, Dey, Sudhansu K., Caprioli, Richard M.
Published in Journal of lipid research (01.11.2009)
Published in Journal of lipid research (01.11.2009)
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Journal Article
Peroxisomes are required for lipid metabolism and muscle function in Drosophila melanogaster
Faust, Joseph E, Manisundaram, Arvind, Ivanova, Pavlina T, Milne, Stephen B, Summerville, James B, Brown, H Alex, Wangler, Michael, Stern, Michael, McNew, James A
Published in PloS one (19.06.2014)
Published in PloS one (19.06.2014)
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Journal Article
Synaptic vesicle-like lipidome of human cytomegalovirus virions reveals a role for SNARE machinery in virion egress
Liu, Sean T.H, Sharon-Friling, Ronit, Ivanova, Pavlina, Milne, Stephen B, Myers, David S, Rabinowitz, Joshua D, Brown, H. Alex, Shenk, Thomas
Published in Proceedings of the National Academy of Sciences - PNAS (02.08.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (02.08.2011)
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