Improving automatic delineation for head and neck organs at risk by Deep Learning Contouring
van Dijk, Lisanne V., Van den Bosch, Lisa, Aljabar, Paul, Peressutti, Devis, Both, Stefan, J.H.M. Steenbakkers, Roel, Langendijk, Johannes A., Gooding, Mark J., Brouwer, Charlotte L.
Published in Radiotherapy and oncology (01.01.2020)
Published in Radiotherapy and oncology (01.01.2020)
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Journal Article
CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines
Brouwer, Charlotte L, Steenbakkers, Roel J.H.M, Bourhis, Jean, Budach, Wilfried, Grau, Cai, Grégoire, Vincent, van Herk, Marcel, Lee, Anne, Maingon, Philippe, Nutting, Chris, O’Sullivan, Brian, Porceddu, Sandro V, Rosenthal, David I, Sijtsema, Nanna M, Langendijk, Johannes A
Published in Radiotherapy and oncology (01.10.2015)
Published in Radiotherapy and oncology (01.10.2015)
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Journal Article
Conference Proceeding
Physiologically Based Pharmacokinetic (PBPK) Model Predictions of Disease Mediated Changes in Drug Disposition in Patients with Nonalcoholic Fatty Liver Disease (NAFLD)
Adiwidjaja, Jeffry, Spires, Jessica, Brouwer, Kim L. R.
Published in Pharmaceutical research (01.03.2024)
Published in Pharmaceutical research (01.03.2024)
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Journal Article
Identifying patients who may benefit from adaptive radiotherapy: Does the literature on anatomic and dosimetric changes in head and neck organs at risk during radiotherapy provide information to help?
Brouwer, Charlotte L, Steenbakkers, Roel J.H.M, Langendijk, Johannes A, Sijtsema, Nanna M
Published in Radiotherapy and oncology (01.06.2015)
Published in Radiotherapy and oncology (01.06.2015)
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Journal Article
Application of Pharmacokinetic Modeling to Characterize Hepatobiliary Disposition of Imaging Agents and Alterations due to Liver Injury in Isolated Perfused Rat Livers
Jeong, Angela, Pastor, Catherine M., Brouwer, Kim L. R.
Published in Pharmaceutical research (01.11.2023)
Published in Pharmaceutical research (01.11.2023)
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Journal Article
Hepatic basolateral efflux contributes significantly to rosuvastatin disposition I: characterization of basolateral versus biliary clearance using a novel protocol in sandwich-cultured hepatocytes
Pfeifer, Nathan D, Yang, Kyunghee, Brouwer, Kim L R
Published in The Journal of pharmacology and experimental therapeutics (01.12.2013)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2013)
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Journal Article
Membrane transporters in drug development and as determinants of precision medicine
Galetin, Aleksandra, Brouwer, Kim L. R., Tweedie, Donald, Yoshida, Kenta, Sjöstedt, Noora, Aleksunes, Lauren, Chu, Xiaoyan, Evers, Raymond, Hafey, Michael J., Lai, Yurong, Matsson, Pär, Riselli, Andrew, Shen, Hong, Sparreboom, Alex, Varma, Manthena V. S., Yang, Jia, Yang, Xinning, Yee, Sook Wah, Zamek-Gliszczynski, Maciej J., Zhang, Lei, Giacomini, Kathleen M.
Published in Nature reviews. Drug discovery (01.04.2024)
Published in Nature reviews. Drug discovery (01.04.2024)
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Journal Article
In vitro methods to support transporter evaluation in drug discovery and development
Brouwer, K L R, Keppler, D, Hoffmaster, K A, Bow, D A J, Cheng, Y, Lai, Y, Palm, J E, Stieger, B, Evers, R
Published in Clinical pharmacology and therapeutics (01.07.2013)
Published in Clinical pharmacology and therapeutics (01.07.2013)
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Journal Article
Risk factors for development of cholestatic drug-induced liver injury: inhibition of hepatic basolateral bile acid transporters multidrug resistance-associated proteins 3 and 4
Köck, Kathleen, Ferslew, Brian C, Netterberg, Ida, Yang, Kyunghee, Urban, Thomas J, Swaan, Peter W, Stewart, Paul W, Brouwer, Kim L R
Published in Drug metabolism and disposition (01.04.2014)
Published in Drug metabolism and disposition (01.04.2014)
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Journal Article
Can they imagine the future? A qualitative study exploring the skills employers seek in pharmaceutical sciences doctoral graduates
McLaughlin, Jacqueline E, Minshew, Lana M, Gonzalez, Daniel, Lamb, Kelsey, Klus, Nicholas J, Aubé, Jeffrey, Cox, Wendy, Brouwer, Kim L R
Published in PloS one (09.09.2019)
Published in PloS one (09.09.2019)
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Journal Article
An updated review on drug-induced cholestasis: Mechanisms and investigation of physicochemical properties and pharmacokinetic parameters
Yang, Kyunghee, Köck, Kathleen, Sedykh, Alexander, Tropsha, Alexander, Brouwer, Kim L.R.
Published in Journal of pharmaceutical sciences (01.09.2013)
Published in Journal of pharmaceutical sciences (01.09.2013)
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Journal Article
18F-FDG PET image biomarkers improve prediction of late radiation-induced xerostomia
van Dijk, Lisanne V., Noordzij, Walter, Brouwer, Charlotte L., Boellaard, Ronald, Burgerhof, Johannes G.M., Langendijk, Johannes A., Sijtsema, Nanna M., Steenbakkers, Roel J.H.M.
Published in Radiotherapy and oncology (01.01.2018)
Published in Radiotherapy and oncology (01.01.2018)
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Journal Article
Phase III randomised controlled trial on PSMA PET/CT guided hypofractionated salvage prostate bed radiotherapy of biochemical failure after radical prostatectomy for prostate cancer (PERYTON-trial): study protocol
Staal, F H E, Janssen, J, Brouwer, C L, Langendijk, J A, Ng Wei Siang, K, Schuit, E, de Jong, I J, Verzijlbergen, J F, Smeenk, R J, Aluwini, S
Published in BMC cancer (15.04.2022)
Published in BMC cancer (15.04.2022)
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Journal Article
Analysis of human C24 bile acids metabolome in serum and urine based on enzyme digestion of conjugated bile acids and LC-MS determination of unconjugated bile acids
Zhu, Pingping, Zhang, Jian, Chen, Yujie, Yin, Shanshan, Su, Mingming, Xie, Guoxiang, Brouwer, Kim L. R., Liu, Changxiao, Lan, Ke, Jia, Wei
Published in Analytical and bioanalytical chemistry (01.08.2018)
Published in Analytical and bioanalytical chemistry (01.08.2018)
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Journal Article
Intracellular drug concentrations and transporters: measurement, modeling, and implications for the liver
Chu, X, Korzekwa, K, Elsby, R, Fenner, K, Galetin, A, Lai, Y, Matsson, P, Moss, A, Nagar, S, Rosania, G R, Bai, J P F, Polli, J W, Sugiyama, Y, Brouwer, K L R
Published in Clinical pharmacology and therapeutics (01.07.2013)
Published in Clinical pharmacology and therapeutics (01.07.2013)
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