Search Results - "BROTO PIERRE" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

SAR and X-ray. A New Approach Combining Fragment-Based Screening and Rational Drug Design: Application to the Discovery of Nanomolar Inhibitors of Src SH2

SAR and X-ray. A New Approach Combining Fragment-Based Screening and Rational Drug Design: Application to the Discovery of Nanomolar Inhibitors of Src SH2

by Lesuisse, Dominique, Lange, Gudrun, Deprez, Pierre, Bénard, Didier, Schoot, Bernard, Delettre, Georges, Marquette, Jean-Pierre, Broto, Pierre, Jean-Baptiste, Véronique, Bichet, Paulette, Sarubbi, Edoardo, Mandine, Eliane
Published in Journal of medicinal chemistry (06.06.2002)

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Journal Article

The Substrate Binding Site of Human Liver Cytochrome P450 2C9: An Approach Using Designed Tienilic Acid Derivatives and Molecular Modeling

The Substrate Binding Site of Human Liver Cytochrome P450 2C9: An Approach Using Designed Tienilic Acid Derivatives and Molecular Modeling

by Mancy, Annah, Broto, Pierre, Dijols, Sylvie, Dansette, Patrick M, Mansuy, Daniel
Published in Biochemistry (Easton) (22.08.1995)

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Journal Article

Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors

Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors

by Lange, G, Lesuisse, D, Deprez, P, Schoot, B, Loenze, P, Benard, D, Marquette, JP, Broto, P, Sarubbi, E, Mandine, E
Published in Journal of medicinal chemistry (20.11.2003)

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Journal Article

Requirements for Specific Binding of Low Affinity Inhibitor Fragments to the SH2 Domain of pp60Src Are Identical to Those for High Affinity Binding of Full Length Inhibitors

Requirements for Specific Binding of Low Affinity Inhibitor Fragments to the SH2 Domain of pp60Src Are Identical to Those for High Affinity Binding of Full Length Inhibitors

by Lange, Gudrun, Lesuisse, Dominique, Deprez, Pierre, Schoot, Bernard, Loenze, Petra, Bénard, Didier, Marquette, Jean-Pierre, Broto, Pierre, Sarubbi, Edoardo, Mandine, Eliane
Published in Journal of medicinal chemistry (20.11.2003)

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Journal Article

Requirements for Specific Binding of Low Affinity Inhibitor Fragments to the SH2 Domain of pp60 Src Are Identical to Those for High Affinity Binding of Full Length Inhibitors

Requirements for Specific Binding of Low Affinity Inhibitor Fragments to the SH2 Domain of pp60 Src Are Identical to Those for High Affinity Binding of Full Length Inhibitors

by Lange, Gudrun, Lesuisse, Dominique, Deprez, Pierre, Schoot, Bernard, Loenze, Petra, Bénard, Didier, Marquette, Jean-Pierre, Broto, Pierre, Sarubbi, Edoardo, Mandine, Eliane
Published in Journal of medicinal chemistry (01.11.2003)

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Journal Article

Principles Governing the Binding of a Class of Non-Peptidic Inhibitors to the SH2 Domain of src Studied by X-ray Analysis

Principles Governing the Binding of a Class of Non-Peptidic Inhibitors to the SH2 Domain of src Studied by X-ray Analysis

by Lange, Gudrun, Lesuisse, Dominique, Deprez, Pierre, Schoot, Bernard, Loenze, Petra, Bénard, Didier, Marquette, Jean-Pierre, Broto, Pierre, Sarubbi, Edoardo, Mandine, Eliane
Published in Journal of medicinal chemistry (04.07.2002)

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Journal Article

Discovery of Thioazepinone Ligands for Src SH2: From Non-specific to Specific Binding

Discovery of Thioazepinone Ligands for Src SH2: From Non-specific to Specific Binding

by Lesuisse, Dominique, Deprez, Pierre, Albert, Eva, Duc, Tran Thien, Sortais, Benoit, Gofflo, Dominique, Jean-Baptiste, Véronique, Marquette, Jean-Pierre, Schoot, Bernard, Sarubbi, Edoardo, Lange, Gudrun, Broto, Pierre, Mandine, Eliane
Published in Bioorganic & medicinal chemistry letters (20.08.2001)

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Journal Article

Hexahydropyridazine-3-carboxylic acid hydrazide and hydrazone derivatives, combinatorial libraries containing same, pharmaceutical compositions containing same and methods of preparation

Hexahydropyridazine-3-carboxylic acid hydrazide and hydrazone derivatives, combinatorial libraries containing same, pharmaceutical compositions containing same and methods of preparation

by Bhatnagar, Neerja, Broto, Pierre, Gourvest, Jean-Francois, Mauger, Jacques
Year of Publication 09.10.2007

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Patent

Hexahydropyridazine-3-carboxylic acid hydrazide and hydrazone derivatives, combinatorial libraries containing same, pharmaceutical compositions containing same and methods of preparation

Hexahydropyridazine-3-carboxylic acid hydrazide and hydrazone derivatives, combinatorial libraries containing same, pharmaceutical compositions containing same and methods of preparation

by BHATNAGAR NEERJA, GOURVEST JEAN-FRANCOIS, MAUGER JACQUES, BROTO PIERRE
Year of Publication 09.10.2007

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Patent

Hexahydropyridazine-3-carboxylic acid hydrazide and hydrazone derivatives, combinatorial libraries containing same, pharmaceutical compositions containing same and methods of preparation

Hexahydropyridazine-3-carboxylic acid hydrazide and hydrazone derivatives, combinatorial libraries containing same, pharmaceutical compositions containing same and methods of preparation

by BHATNAGAR NEERJA, GOURVEST JEAN-FRANCOIS, MAUGER JACQUES, BROTO PIERRE
Year of Publication 29.09.2005

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Patent

NOVEL HEXAHYDRO-PYRIDAZINE-3-CARBOCYLIC ACID HYDRAZIDE OR HYDRAZONE DERIVATIVES, COMBINATORIAL LIBRARIES CONTAINING SAME, USE THEREOF AS MEDICINES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND METHODS FOR PREPARING SAME

NOVEL HEXAHYDRO-PYRIDAZINE-3-CARBOCYLIC ACID HYDRAZIDE OR HYDRAZONE DERIVATIVES, COMBINATORIAL LIBRARIES CONTAINING SAME, USE THEREOF AS MEDICINES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND METHODS FOR PREPARING SAME

by GOURVEST, JEAN-FRANCOIS, BROTO, PIERRE, BHATNAGAR, NEERJA, MAUGER, JACQUES
Year of Publication 23.03.2005

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Patent

DERIVES HYDRAZIDE OU HYDRAZONE DE L'ACIDE HEXAHYDROPYRIDAZINE-3-CARBOXYLIQUE, CHIMIOTHEQUES ET COMPOSITIONS PHARMACEUTIQUES LES CONTENANT, UTILISATION COMME MEDICAMENTS, ET PROCEDE DE PREPARATION

DERIVES HYDRAZIDE OU HYDRAZONE DE L'ACIDE HEXAHYDROPYRIDAZINE-3-CARBOXYLIQUE, CHIMIOTHEQUES ET COMPOSITIONS PHARMACEUTIQUES LES CONTENANT, UTILISATION COMME MEDICAMENTS, ET PROCEDE DE PREPARATION

by GOURVEST JEAN FRANCOIS, BHATNAGAR NEERJA, MAUGER JACQUES, BROTO PIERRE
Year of Publication 27.08.2004

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Patent

NOVEL HEXAHYDRO-PYRIDAZINE-3-CARBOCYLIC ACID HYDRAZIDE OR HYDRAZONE DERIVATIVES, COMBINATORIAL LIBRARIES CONTAINING SAME, USE THEREOF AS MEDICINES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND METHODS FOR PREPARING SAME

NOVEL HEXAHYDRO-PYRIDAZINE-3-CARBOCYLIC ACID HYDRAZIDE OR HYDRAZONE DERIVATIVES, COMBINATORIAL LIBRARIES CONTAINING SAME, USE THEREOF AS MEDICINES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND METHODS FOR PREPARING SAME

by JACQUES MAUGER, PIERRE BROTO, NEERJA BHATNAGAR, JEAN-FRANCOIS GOURVEST
Year of Publication 31.12.2003

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Patent

NOVEL HEXAHYDRO-PYRIDAZINE-3-CARBOCYLIC ACID HYDRAZIDE OR HYDRAZONE DERIVATIVES, COMBINATORIAL LIBRARIES CONTAINING SAME, USE THEREOF ASMEDICINES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND METHODS FOR PREPARING SAME

NOVEL HEXAHYDRO-PYRIDAZINE-3-CARBOCYLIC ACID HYDRAZIDE OR HYDRAZONE DERIVATIVES, COMBINATORIAL LIBRARIES CONTAINING SAME, USE THEREOF ASMEDICINES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND METHODS FOR PREPARING SAME

by GOURVEST, JEAN-FRANCOIS, BROTO, PIERRE, BHATNAGAR, NEERJA, MAUGER, JACQUES
Year of Publication 24.12.2003

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Patent

New hexahydropyridazine-3-carboxylic hydrazide or hydrazone derivatives are protease and kinase inhibitors, useful for treating cancer and cardiovascular, CNS, inflammatory, infectious or bone diseases

New hexahydropyridazine-3-carboxylic hydrazide or hydrazone derivatives are protease and kinase inhibitors, useful for treating cancer and cardiovascular, CNS, inflammatory, infectious or bone diseases

by GOURVEST JEAN FRANCOIS, BHATNAGAR NEERJA, MAUGER JACQUES, BROTO PIERRE
Year of Publication 19.12.2003

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Patent

PYRIDAZINDERIVATE, DEREN VERWENDUNG ALS HEILMITTEL, UND DEREN VERFAHREN ZU IHRER VERWENDUNG

PYRIDAZINDERIVATE, DEREN VERWENDUNG ALS HEILMITTEL, UND DEREN VERFAHREN ZU IHRER VERWENDUNG

by GOURVEST, JEAN-FRANCOIS, BROTO, PIERRE, BENARD, DIDIER, BHATNAGAR, NEERJA, MAUGER, JACQUES
Year of Publication 06.06.2007

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Patent

DERIVADOS DE PIRIDAZINA, SUA UTILIZACAO COMO MEDICAMENTOS E SEU PROCESSO DE PREPARACAO

DERIVADOS DE PIRIDAZINA, SUA UTILIZACAO COMO MEDICAMENTOS E SEU PROCESSO DE PREPARACAO

by BROTO, PIERRE, BENARD, DIDIER, NEERJA BHATNAGAR, JEAN-FRANCOIS GOURVEST, MAUGER, JACQUES
Year of Publication 31.10.2006

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Patent

PYRIDAZINDERIVATE, DEREN VERWENDUNG ALS HEILMITTEL, UND DEREN VERFAHREN ZU IHRER VERWENDUNG

PYRIDAZINDERIVATE, DEREN VERWENDUNG ALS HEILMITTEL, UND DEREN VERFAHREN ZU IHRER VERWENDUNG

by GOURVEST, JEAN-FRANCOIS, BROTO, PIERRE, BENARD, DIDIER, BHATNAGAR, NEERJA, MAUGER, JACQUES
Year of Publication 15.07.2006

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Patent

PYRIDAZINE DERIVATIVES, USE OF THE SAME AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND METHOD FOR PRODUCING THE SAME

PYRIDAZINE DERIVATIVES, USE OF THE SAME AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND METHOD FOR PRODUCING THE SAME

by GOURVEST, JEAN-FRANCOIS, BROTO, PIERRE, BENARD, DIDIER, BHATNAGAR, NEERJA, MAUGER, JACQUES
Year of Publication 14.06.2006

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Patent

ΠΑΡΑΓΩΓΑ ΠΥΡΙΔΑΖΙΝΗΣ, Η ΧΡΗΣΗ ΤΟΥΣ ΩΣ ΦΑΡΜΑΚΕΥΤΙΚΑ ΣΚΕΥΑΣΜΑΤΑ ΚΑΙ Η ΔΙΑΔΙΚΑΣΙΑ ΠΑΡΑΣΚΕΥΗΣ ΤΟΥΣ

ΠΑΡΑΓΩΓΑ ΠΥΡΙΔΑΖΙΝΗΣ, Η ΧΡΗΣΗ ΤΟΥΣ ΩΣ ΦΑΡΜΑΚΕΥΤΙΚΑ ΣΚΕΥΑΣΜΑΤΑ ΚΑΙ Η ΔΙΑΔΙΚΑΣΙΑ ΠΑΡΑΣΚΕΥΗΣ ΤΟΥΣ

by BHATNAGAR NEERJA, GOURVEST JEAN-FRANCOIS, BERARD DIDIER, MAUGER JACQUES, BROTO PIERRE
Year of Publication 13.03.2013

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Patent