Deep mutational scanning of essential bacterial proteins can guide antibiotic development
Dewachter, Liselot, Brooks, Aaron N., Noon, Katherine, Cialek, Charlotte, Clark-ElSayed, Alia, Schalck, Thomas, Krishnamurthy, Nandini, Versées, Wim, Vranken, Wim, Michiels, Jan
Published in Nature communications (16.01.2023)
Published in Nature communications (16.01.2023)
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Journal Article
Hyperglycemia and T Cell infiltration are associated with stromal and epithelial prostatic hyperplasia in the nonobese diabetic mouse
Aaron‐Brooks, LaTayia M., Sasaki, Takeshi, Vickman, Renee E., Wei, Lin, Franco, Omar E., Ji, Yuan, Crawford, Susan E., Hayward, Simon W.
Published in The Prostate (01.06.2019)
Published in The Prostate (01.06.2019)
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Journal Article
TNF is a potential therapeutic target to suppress prostatic inflammation and hyperplasia in autoimmune disease
Vickman, Renee E., Aaron-Brooks, LaTayia, Zhang, Renyuan, Lanman, Nadia A., Lapin, Brittany, Gil, Victoria, Greenberg, Max, Sasaki, Takeshi, Cresswell, Gregory M., Broman, Meaghan M., Paez, J. Sebastian, Petkewicz, Jacqueline, Talaty, Pooja, Helfand, Brian T., Glaser, Alexander P., Wang, Chi-Hsiung, Franco, Omar E., Ratliff, Timothy L., Nastiuk, Kent L., Crawford, Susan E., Hayward, Simon W.
Published in Nature communications (19.04.2022)
Published in Nature communications (19.04.2022)
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Journal Article
Transcriptional neighborhoods regulate transcript isoform lengths and expression levels
Brooks, Aaron N, Hughes, Amanda L, Clauder-Münster, Sandra, Mitchell, Leslie A, Boeke, Jef D, Steinmetz, Lars M
Published in Science (American Association for the Advancement of Science) (04.03.2022)
Published in Science (American Association for the Advancement of Science) (04.03.2022)
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Journal Article
Author Correction: Deep mutational scanning of essential bacterial proteins can guide antibiotic development
Dewachter, Liselot, Brooks, Aaron N., Noon, Katherine, Cialek, Charlotte, Clark-ElSayed, Alia, Schalck, Thomas, Krishnamurthy, Nandini, Versées, Wim, Vranken, Wim, Michiels, Jan
Published in Nature communications (06.02.2023)
Published in Nature communications (06.02.2023)
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Journal Article
Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions
Zhao, Yu, Coelho, Camila, Hughes, Amanda L., Lazar-Stefanita, Luciana, Yang, Sandy, Brooks, Aaron N., Walker, Roy S.K., Zhang, Weimin, Lauer, Stephanie, Hernandez, Cindy, Cai, Jitong, Mitchell, Leslie A., Agmon, Neta, Shen, Yue, Sall, Joseph, Fanfani, Viola, Jalan, Anavi, Rivera, Jordan, Liang, Feng-Xia, Bader, Joel S., Stracquadanio, Giovanni, Steinmetz, Lars M., Cai, Yizhi, Boeke, Jef D.
Published in Cell (22.11.2023)
Published in Cell (22.11.2023)
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Journal Article
Design, construction, and functional characterization of a tRNA neochromosome in yeast
Schindler, Daniel, Walker, Roy S.K., Jiang, Shuangying, Brooks, Aaron N., Wang, Yun, Müller, Carolin A., Cockram, Charlotte, Luo, Yisha, García, Alicia, Schraivogel, Daniel, Mozziconacci, Julien, Pena, Noah, Assari, Mahdi, Sánchez Olmos, María del Carmen, Zhao, Yu, Ballerini, Alba, Blount, Benjamin A., Cai, Jitong, Ogunlana, Lois, Liu, Wei, Jönsson, Katarina, Abramczyk, Dariusz, Garcia-Ruiz, Eva, Turowski, Tomasz W., Swidah, Reem, Ellis, Tom, Pan, Tao, Antequera, Francisco, Shen, Yue, Nieduszynski, Conrad A., Koszul, Romain, Dai, Junbiao, Steinmetz, Lars M., Boeke, Jef D., Cai, Yizhi
Published in Cell (22.11.2023)
Published in Cell (22.11.2023)
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Journal Article
MtrA modulates Mycobacterium tuberculosis cell division in host microenvironments to mediate intrinsic resistance and drug tolerance
Peterson, Eliza J.R., Brooks, Aaron N., Reiss, David J., Kaur, Amardeep, Do, Julie, Pan, Min, Wu, Wei-Ju, Morrison, Robert, Srinivas, Vivek, Carter, Warren, Arrieta-Ortiz, Mario L., Ruiz, Rene A., Bhatt, Apoorva, Baliga, Nitin S.
Published in Cell reports (Cambridge) (29.08.2023)
Published in Cell reports (Cambridge) (29.08.2023)
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Journal Article
Data-driven integration of genome-scale regulatory and metabolic network models
Imam, Saheed, Schäuble, Sascha, Brooks, Aaron N, Baliga, Nitin S, Price, Nathan D
Published in Frontiers in microbiology (05.05.2015)
Published in Frontiers in microbiology (05.05.2015)
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Journal Article
Adaptation of cells to new environments
Brooks, Aaron N, Turkarslan, Serdar, Beer, Karlyn D, Lo, Fang Yin, Baliga, Nitin S
Published in Wiley interdisciplinary reviews. Systems biology and medicine (01.09.2011)
Published in Wiley interdisciplinary reviews. Systems biology and medicine (01.09.2011)
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Journal Article
A system‐level model for the microbial regulatory genome
Brooks, Aaron N, Reiss, David J, Allard, Antoine, Wu, Wei‐Ju, Salvanha, Diego M, Plaisier, Christopher L, Chandrasekaran, Sriram, Pan, Min, Kaur, Amardeep, Baliga, Nitin S
Published in Molecular systems biology (01.07.2014)
Published in Molecular systems biology (01.07.2014)
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Journal Article
Disrupting the ArcA Regulatory Network Amplifies the Fitness Cost of Tetracycline Resistance in Escherichia coli
Arrieta-Ortiz, Mario L, Pan, Min, Kaur, Amardeep, Pepper-Tunick, Evan, Srinivas, Vivek, Dash, Ananya, Immanuel, Selva Rupa Christinal, Brooks, Aaron N, Shepherd, Tyson R, Baliga, Nitin S
Published in mSystems (23.02.2023)
Published in mSystems (23.02.2023)
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Journal Article
Macromolecular networks and intelligence in microorganisms
Westerhoff, Hans V, Brooks, Aaron N, Simeonidis, Evangelos, García-Contreras, Rodolfo, He, Fei, Boogerd, Fred C, Jackson, Victoria J, Goncharuk, Valeri, Kolodkin, Alexey
Published in Frontiers in microbiology (22.07.2014)
Published in Frontiers in microbiology (22.07.2014)
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Journal Article
Evolution of context dependent regulation by expansion of feast/famine regulatory proteins
Plaisier, Christopher L, Lo, Fang-Yin, Ashworth, Justin, Brooks, Aaron N, Beer, Karlyn D, Kaur, Amardeep, Pan, Min, Reiss, David J, Facciotti, Marc T, Baliga, Nitin S
Published in BMC systems biology (14.11.2014)
Published in BMC systems biology (14.11.2014)
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Journal Article
Emergency department management of patients with rib fracture based on a clinical practice guideline
Hamilton, Chase, Barnett, Lauren, Trop, Allison, Leininger, Brian, Olson, Adam, Brooks, Aaron, Clark, Daniel, Schroeppel, Thomas
Published in Trauma surgery & acute care open (01.12.2017)
Published in Trauma surgery & acute care open (01.12.2017)
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Journal Article