GABAA α1 subunit knock-out mice do not show a hyperlocomotor response following amphetamine or cocaine treatment
REYNOLDS, D. S, O'MEARA, G. F, NEWMAN, R. J, BROMIDGE, F. A, ATACK, J. R, WHITING, P. J, ROSAHL, T. W, DAWSON, G. R
Published in Neuropharmacology (01.02.2003)
Published in Neuropharmacology (01.02.2003)
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GABA(A) alpha 1 subunit knock-out mice do not show a hyperlocomotor response following amphetamine or cocaine treatment
Reynolds, D S, O'Meara, G F, Newman, R J, Bromidge, F A, Atack, J R, Whiting, P J, Rosahl, T W, Dawson, G R
Published in Neuropharmacology (01.02.2003)
Published in Neuropharmacology (01.02.2003)
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Discovery of Imidazo[1,2-b][1,2,4]triazines as GABA sub(A) alpha 2/3 Subtype Selective Agonists for the Treatment of Anxiety
Russell, MGN, Carling, R W, Street, L J, Hallett, D J, Goodacre, S, Mezzogori, E, Reader, M, Cook, S M, Bromidge, F A, Newman, R, Smith, A J, Wafford, KA, Marshall, G R, Reynolds, D S
Published in Journal of medicinal chemistry (23.02.2006)
Published in Journal of medicinal chemistry (23.02.2006)
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Discovery of Functionally Selective 7,8,9,10-Tetrahydro-7,10-ethano-1,2,4- triazolo[3,4-a]phthalazines as GABA sub(A) Receptor Agonists at the alpha sub(3) Subunit
Russell, MGN, Carling, R W, Atack, J R, Bromidge, F A, Cook, S M, Hunt, P, Isted, C, Lucas, M, McKernan, R M, Mitchinson, A, Moore, K W, Narquizian, R, Macaulay, A J, Thomas, D
Published in Journal of medicinal chemistry (10.03.2005)
Published in Journal of medicinal chemistry (10.03.2005)
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3-heteroaryl-2-pyridones: Benzodiazepine site ligands with functional selectivity for alpha 2/alpha 3-subtypes of human GABA(A) receptor-ion channels
Collins, Moyes, C, Davey, WB, Rowley, M, Bromidge, FA, Quirk, K, Atack, McKernan, RM, Thompson, SA, Wafford, K, Dawson, GR, Pike, A, Sohal, B, Tsou, NN, Ball, RG, Castro, JL
Published in Journal of medicinal chemistry (25.04.2002)
Published in Journal of medicinal chemistry (25.04.2002)
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Synthesis and biological evaluation of 3-heterocyclyl-7,8,9,10-tetrahydro-(7,10-ethano)-1,2,4-triazolo[3,4-a]phthalazines and analogues as subtype-selective inverse agonists for the GABA(A)alpha 5 benzodiazepine binding site
Street, LJ, Sternfeld, F, Jelley, RA, Reeve, AJ, Carling, RW, Moore, KW, McKernan, RM, Sohal, B, Cook, S, Pike, A, Dawson, GR, Bromidge, FA, Wafford, KA, Seabrook, GR, Thompson, SA, Marshall, G, Pillai, GV, Castro, JL, Atack, MacLeod, AM
Published in Journal of medicinal chemistry (01.07.2004)
Published in Journal of medicinal chemistry (01.07.2004)
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Journal Article
Discovery of functionally selective 7,8,9,10-tetrahydro-7,10-ethano-1,2,4-triazolo[3,4-a]phthalazines as GABA(A) receptor agonists at the alpha(3) subunit
Russell, MGN, Carling, RW, Atack, Bromidge, FA, Cook, SM, Hunt, P, Isted, C, Lucas, M, McKernan, RM, Mitchinson, A, Moore, KW, Narquizian, R, Macaulay, AJ, Thomas, D, Thompson, SA, Wafford, KA, Castro, JL
Published in Journal of medicinal chemistry (10.03.2005)
Published in Journal of medicinal chemistry (10.03.2005)
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Journal Article
Discovery of imidazo[1,2-b][1,2,4]triazines as GABA(A) alpha 2/3 subtype selective agonists for the treatment of anxiety
Russell, MGN, Carling, RW, Street, LJ, Hallett, DJ, Goodacre, S, Mezzogori, E, Reader, M, Cook, SM, Bromidge, FA, Newman, R, Smith, AJ, Wafford, KA, Marshall, GR, Reynolds, DS, Dias, R, Ferris, P, Stanley, J, Lincoln, R, Tye, SJ, Sheppard, WFA, Sohal, B, Pike, A, Dominguez, M, Atack, Castro, JL
Published in Journal of medicinal chemistry (23.02.2006)
Published in Journal of medicinal chemistry (23.02.2006)
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Journal Article
GABA sub(A) alpha 1 subunit knock-out mice do not show a hyperlocomotor response following amphetamine or cocaine treatment
Reynolds, D S, O'Meara, G F, Newman, R J, Bromidge, F A, Atack, J R, Whiting, P J, Rosahl, T W, Dawson, G R
Published in Neuropharmacology (01.02.2003)
Published in Neuropharmacology (01.02.2003)
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Journal Article
Identification of amino acid residues responsible for the alpha 5 subunit binding selectivity of L-655,708, a benzodiazepine binding site ligand at the GABA sub(A) receptor
Casula, MA, Bromidge, F A, Pillai, G V, Wingrove, P B, Martin, K, Maubach, K, Seabrook, G R, Whiting, P J, Hadingham, K L
Published in Journal of neurochemistry (01.04.2001)
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Published in Journal of neurochemistry (01.04.2001)
Journal Article
Identification of amino acid residues responsible for the alpha5 subunit binding selectivity of L-655,708, a benzodiazepine binding site ligand at the GABA(A) receptor
Casula, M A, Bromidge, F A, Pillai, G V, Wingrove, P B, Martin, K, Maubach, K, Seabrook, G R, Whiting, P J, Hadingham, K L
Published in Journal of neurochemistry (01.04.2001)
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Published in Journal of neurochemistry (01.04.2001)
Journal Article
N-(indol-3-ylglyoxylyl)piperidines : High affinity agonists of human GABA-A receptors containing the α1 subunit
COLLINS, I, DAVEY, W. B, ROWLEY, M, QUIRK, K, BROMIDGE, F. A, MCKERNAN, R. M, THOMPSON, S.-A, WAFFORD, K. A
Published in Bioorganic & medicinal chemistry letters (19.06.2000)
Published in Bioorganic & medicinal chemistry letters (19.06.2000)
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Journal Article
N-(indol-3-ylglyoxylyl)piperidines: high affinity agonists of human GABA-A receptors containing the alpha1 subunit
Collins, I, Davey, W B, Rowley, M, Quirk, K, Bromidge, F A, McKernan, R M, Thompson, S A, Wafford, K A
Published in Bioorganic & medicinal chemistry letters (19.06.2000)
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Published in Bioorganic & medicinal chemistry letters (19.06.2000)
Journal Article
6,7-Dihydro-2-benzothiophen-4(5H)-ones: A novel class of GABA-A alpha 5 receptor inverse agonists
Chambers, MS, Atack, Bromidge, FA, Broughton, HB, Cook, S, Dawson, GR, Hobbs, SC, Maubach, KA, Reeve, AJ, Seabrook, GR, Wafford, K, MacLeod, AM
Published in Journal of medicinal chemistry (14.03.2002)
Published in Journal of medicinal chemistry (14.03.2002)
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