Circulating mitochondrial DAMPs cause inflammatory responses to injury
Zhang, Qin, Itagaki, Kiyoshi, Raoof, Mustafa, Sursal, Tolga, Sumi, Yuka, Junger, Wolfgang, Chen, Yu, Hauser, Carl J, Brohi, Karim
Published in Nature (04.03.2010)
Published in Nature (04.03.2010)
Get full text
Journal Article
The systemic immune response to trauma: an overview of pathophysiology and treatment
Lord, Janet M, Prof, Midwinter, Mark J, Prof, Chen, Yen-Fu, PhD, Belli, Antonio, MD, Brohi, Karim, Prof, Kovacs, Elizabeth J, Prof, Koenderman, Leo, Prof, Kubes, Paul, Prof, Lilford, Richard J, Prof
Published in The Lancet (British edition) (18.10.2014)
Published in The Lancet (British edition) (18.10.2014)
Get full text
Journal Article
Activated Protein C Drives the Hyperfibrinolysis of Acute Traumatic Coagulopathy
Davenport, Ross A, Guerreiro, Maria, Frith, Daniel, Rourke, Claire, Platton, Sean, Cohen, Mitchell, Pearse, Rupert, Thiemermann, Chris, Brohi, Karim
Published in Anesthesiology (Philadelphia) (01.01.2017)
Published in Anesthesiology (Philadelphia) (01.01.2017)
Get full text
Journal Article
Circulating Histones Are Mediators of Trauma-associated Lung Injury
ABRAMS, Simon T, NAN ZHANG, GUOZHENG WANG, TON, Cheng-Hock, MANSON, Joanna, TINGTING LIU, DART, Caroline, BALUWA, Florence, SUSAN SIYU WANG, BROHI, Karim, KIPAR, Anja, WEIPING YU
Published in American journal of respiratory and critical care medicine (15.01.2013)
Published in American journal of respiratory and critical care medicine (15.01.2013)
Get full text
Journal Article
Functional definition and characterization of acute traumatic coagulopathy
Davenport, Ross, Manson, Joanna, De'Ath, Henry, Platton, Sean, Coates, Amy, Allard, Shubha, Hart, Daniel, Pearse, Rupert, Pasi, K John, MacCallum, Peter, Stanworth, Simon, Brohi, Karim
Published in Critical care medicine (01.12.2011)
Published in Critical care medicine (01.12.2011)
Get more information
Journal Article
Hemostatic resuscitation is neither hemostatic nor resuscitative in trauma hemorrhage
Khan, Sirat, Brohi, Karim, Chana, Manik, Raza, Imran, Stanworth, Simon, Gaarder, Christine, Davenport, Ross
Published in The journal of trauma and acute care surgery (01.03.2014)
Published in The journal of trauma and acute care surgery (01.03.2014)
Get more information
Journal Article
Critical role of activated protein C in early coagulopathy and later organ failure, infection and death in trauma patients
Cohen, Mitchell Jay, Call, Mariah, Nelson, Mary, Calfee, Carolyn S, Esmon, Charles T, Brohi, Karim, Pittet, Jean Francois
Published in Annals of surgery (01.02.2012)
Published in Annals of surgery (01.02.2012)
Get more information
Journal Article
Diagnosis and Treatment of Hyperfibrinolysis in Trauma (A European Perspective)
Gall, Lewis S, Brohi, Karim, Davenport, Ross A
Published in Seminars in thrombosis and hemostasis (01.03.2017)
Published in Seminars in thrombosis and hemostasis (01.03.2017)
Get more information
Journal Article
Acute coagulopathy of trauma: mechanism, identification and effect
Brohi, Karim, Cohen, Mitchell J, Davenport, Ross A
Published in Current opinion in critical care (01.12.2007)
Published in Current opinion in critical care (01.12.2007)
Get more information
Journal Article
The S100A10 Pathway Mediates an Occult Hyperfibrinolytic Subtype in Trauma Patients
Gall, Lewis S, Vulliamy, Paul, Gillespie, Scarlett, Jones, Timothy F, Pierre, Rochelle S J, Breukers, Sabine E, Gaarder, Christine, Juffermans, Nicole P, Maegele, Marc, Stensballe, Jakob, Johansson, Pär I, Davenport, Ross A, Brohi, Karim
Published in Annals of surgery (01.06.2019)
Published in Annals of surgery (01.06.2019)
Get more information
Journal Article
Damage control resuscitation using blood component therapy in standard doses has a limited effect on coagulopathy during trauma hemorrhage
Khan, Sirat, Davenport, Ross, Raza, Imran, Glasgow, Simon, De’Ath, Henry D., Johansson, Pär I., Curry, Nicola, Stanworth, Simon, Gaarder, Christine, Brohi, Karim
Published in Intensive care medicine (01.02.2015)
Published in Intensive care medicine (01.02.2015)
Get full text
Journal Article
Detection of acute traumatic coagulopathy and massive transfusion requirements by means of rotational thromboelastometry: an international prospective validation study
Hagemo, Jostein S, Christiaans, Sarah C, Stanworth, Simon J, Brohi, Karim, Johansson, Pär I, Goslings, J Carel, Naess, Paal A, Gaarder, Christine
Published in Critical care (London, England) (23.03.2015)
Published in Critical care (London, England) (23.03.2015)
Get full text
Journal Article
Scavenging Circulating Mitochondrial DNA as a Potential Therapeutic Option for Multiple Organ Dysfunction in Trauma Hemorrhage
Aswani, Andrew, Manson, Joanna, Itagaki, Kiyoshi, Chiazza, Fausto, Collino, Massimo, Wupeng, Winston Liao, Chan, Tze Khee, Wong, W S Fred, Hauser, Carl J, Thiemermann, Chris, Brohi, Karim
Published in Frontiers in immunology (08.05.2018)
Published in Frontiers in immunology (08.05.2018)
Get full text
Journal Article
Alterations in platelet behavior after major trauma: adaptive or maladaptive?
Vulliamy, Paul, Kornblith, Lucy Z., Kutcher, Matthew E., Cohen, Mitchell J., Brohi, Karim, Neal, Matthew D.
Published in Platelets (Edinburgh) (03.04.2021)
Published in Platelets (Edinburgh) (03.04.2021)
Get full text
Journal Article
Prevalence, predictors and outcome of hypofibrinogenaemia in trauma: a multicentre observational study
Hagemo, Jostein S, Stanworth, Simon, Juffermans, Nicole P, Brohi, Karim, Cohen, Mitchell, Johansson, Pär I, Røislien, Jo, Eken, Torsten, Næss, Paal A, Gaarder, Christine
Published in Critical care (London, England) (26.03.2014)
Published in Critical care (London, England) (26.03.2014)
Get full text
Journal Article
Association of red blood cells and plasma transfusion versus red blood cell transfusion only with survival for treatment of major traumatic hemorrhage in prehospital setting in England: a multicenter study
Tucker, Harriet, Brohi, Karim, Tan, Joachim, Aylwin, Christopher, Bloomer, Roger, Cardigan, Rebecca, Davenport, Ross, Davies, Edward D, Godfrey, Phillip, Hawes, Rachel, Lyon, Richard, McCullagh, Josephine, Stanworth, Simon, Thompson, Julian, Uprichard, James, Walsh, Simon, Weaver, Anne, Green, Laura
Published in Critical care (London, England) (17.01.2023)
Published in Critical care (London, England) (17.01.2023)
Get full text
Journal Article