QUINOXALINE DERIVATIVES USEFUL AS FGFR KINASE MODULATORS
Hostyn, Steven Anna, Jones, Russell Mark, Cuyckens, Filip Albert Celine, Vermeulen, Wim, Broggini, Diego Fernando Domenico
Year of Publication 25.10.2018
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Year of Publication 25.10.2018
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PROCEDIMIENTO PARA LA FABRICACIÓN DE (6R,10S)-10-{4-[5-CLORO-2-(4-CLORO-1H-1,2,3-TRIAZOL-1-IL)FENIL]-6-OXO-1(6H)-PIRIMIDINIL}-1-(DIFLUOROMETIL)-6-METIL-1,4,7,8,9,10-HEXAHIDRO-11,15-(METENO)PIRAZOLO[4,3-B][1,7]DIAZACICLOTETRADECIN-5(6H)-ONA
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Year of Publication 11.01.2023
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Year of Publication 11.01.2023
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THIAZOLOPYRIDIN-2-YLOXY-PHENYL AND THIAZOLOPYRAZIN-2-YLOXY-PHENYL AMINES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE
FOURIE, ANNE M, LIANG, JIMMY T, MANI, NEELAKANDHA S, DENG, XIAOHU, GOMEZ, LAURENT, TANIS, VIRGINIA M, GRICE, CHERYL A, CHROVIAN, CHRISTA C, KEARNEY, AARON M, BACANI, GENESIS M, LOCHNER, SUSANNE, SEPASSI, KIA, LEE-DUTRA, ALICE, LANDRY-BAYLE, ADRIENNE M, BROGGINI, DIEGO, WIENER, JOHN J. M, ZINSER, HARTMUT, CHEUNG, EUGENE Y, SANTILLAN, ALEJANDRO, JR, SAPPEY, KATHLEEN C, WICKBOLDT, ALVAH T
Year of Publication 25.04.2017
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Year of Publication 25.04.2017
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NOVEL SYNTHESIS OPTIONS FOR THE PREPARATION OF (6R, 10S)-10-{4-[5-CHLORO-2-(4-CHLORO-1H-1, 2, 3-TRIAZOL-1-YL) PHENYL]-6-OXO-1 (6H)-PYRIMIDINYL}-1-(DIOXYMETHYL)-6-METHYL-1, 4, 7, 8, 9, 10-HEXAHYDRO-11, 15-(METHYLENE BRIDGE) PYRAZOLO [4, 3-B] [1, 7] DIAZEROCYCLIDINE-5 (6H)-ONE
KOLOTUCHIN, SERGEY, BEN HAIM, C, KUNIEL NADINE, LEMAIRE SEBASTIEN FRANCOIS EUGENE, CHERNICHENKO, KRASSIMIR, MUKHERJEE SUMAN, FAN YU, TSAO DANIEL CHUN TECK, WAGSCHAL, STEPHEN, A, BROGGINI DIEGO FERNANDO DOMENICO, YUAN CHANGXIA, ZHENG BIN, SINGH AMARNAUTH, XIAO YI, SIMMONS ERIC M, WEI YIROU
Year of Publication 19.04.2022
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Year of Publication 19.04.2022
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NOVEL SYNT
WAGSCHAL Simon Albert, CAO Duy Chi Trung, FAN Yu, BROGGINI Diego Fernando Domenico, ZHENG Bin, CUNIERE Nicolas, Sébastien François Emmanuel LEMAIRE, XIAO Yi, WEI Carolyn S, KOLOTUCHIN Sergei, BEN HAIM Cyril, MUKHERJEE Subha, SIMMONS Eric M, SINGH Amarjit, CHERNICHENKO Kostiantyn, YUAN Changxia
Year of Publication 06.04.2022
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Year of Publication 06.04.2022
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A process toward the manufacture of (6R,10S)-10-{4-[5-chloro-2-(4-chloro-1H-1,2,3-triazol-1-yl)phenyl]-6-oxo-1(6H)-pyrimidinyl}- 1-(difluoromethyl)-6-methyl-1,4,7,8,9,10-hexahydro-11,15-(metheno)pyrazolo[4,3-B][1,7]diazacyclotetradecin-5(6H)-one
REUTER, KARL, SINGH, AMARJIT, PEREGO, LUCA ALESSANDRO, WEI, CAROLYN S, WAGSCHAL, SIMON ALBERT, ZHDANKO, ALEXANDER, TRAN, NGOC DUC, WISNIEWSKI, STEVEN R, XIOURAS, CHRISTOS, LEMAIRE, SEBASTIEN FRANCOIS EMMANUEL, JAMISON, CHRISTOPHER ROBERT, SCHMALZBAUER, BJORN, MATCHABA, KIRAN, SFOUGGATAKIS, CHRIS, MUKHERJEE, SUBHA, CUNIERE, NICOLAS, ZHENG, BIN, GALLAGHER, WILLIAM P, SKLIAR, DIMITRI, LUO, HELEN Y, JUSSEAU, XAVIER JEAN-MARIE, BEN HAIM, CYRIL, KOLOTUCHIN, SERGEI, ORTIZ, ADRIAN, KOSCHKER, PHILIPP, EASTGATE, MARTIN D, BROGGINI, DIEGO FERNANDO DOMENICO, MOWER, MATTHEW PENFIELD, CHERNICHENKO, KOSTIANTYN, RAHMANI, RAMDANE, CAO, DUY CHI TRUNG
Year of Publication 01.08.2022
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Year of Publication 01.08.2022
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ΔΙΑΔΙΚΑΣΙΑ ΓΙΑ ΤΗΝ ΠΑΡΑΣΚΕΥΗ ΡΥΘΜΙΣΤΩΝ ΤΟΥ Η3 ΥΠΟΔΟΧΕΑ ΙΣΤΑΜΙΝΗΣ
PIPPEL, Daniel, J, MAURER, Adrian, BROGGINI, Diego, LELLEK, Vit, LOCHNER, Susanne, MANI, Neelakandha, S, YOUNG, Lana
Year of Publication 07.03.2018
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Year of Publication 07.03.2018
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PROCESS FOR THE PREPARATION AND RECRYSTALLIZATION OF CRYSTALLINE HEMITARTRATE OF BENZOIMIDAZOL-2-YL PYRIMIDINE DERIVATIVE
CESCO-CANCIAN SERGIO, MAPES CHRISTOPHER, M, PALMER DAVID, C, MANI NEELAKANDHA, S, LOCHNER SUSANNE, XIAO TONG, GRIMM JEFFREY, S, BROGGINI DIEGO, PIPPEL DANIEL, J
Year of Publication 29.08.2014
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Year of Publication 29.08.2014
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PROCESS FOR THE PREPARATION OF HISTAMINE H3 RECEPTOR MODULATORS
PIPPEL, DANIEL, J, MANI, NEELAKANDHA, S, BROGGINI, DIEGO, LELLEK, VIT, MAURER, ADRIAN, LOCHNER, SUSANNE, YOUNG, LANA
Year of Publication 21.03.2012
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Year of Publication 21.03.2012
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OPCIONES SINTÉTICAS HACIA LA FABRICACIÓN DE (6R,10S)-10-{4-[5-CLORO-2-(4-CLORO-1H-1,2,3-TRIAZOL-1-IL)FENIL]-6-OXO-1(6H)-PIRIMIDINIL}-1-(DIFLUOROMETIL)-6-METIL-1,4,7,8,9,10-HEXAHIDRO-11,15-(METENO)PIRAZOL[4,3-B][1,7]DIAZACICLOTETRADECIN-5(6H)-ONA
SINGH, AMARJIT, SIMMONS, ERIC M, XIAO, YI, WEI, CAROLYN S, WAGSCHAL, SIMON ALBERT, FAN, YU, KOLOTUCHIN, SERGEI, YUAN, CHANGXIA, BEN HAM, CYRIL, BROGGINI, DIEGO FERNANDO DOMENICO, CHERNICHENKO, KOSTIANTYN, LEMAIRE, SBASTIEN FRANOIS EMMANUEL, MUKHERJEE, SUBHA, CUNIERE, NICOLAS, ZHENG, BIN, CAO, DUY CHI TRUNG
Year of Publication 20.10.2021
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Year of Publication 20.10.2021
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THIAZOLOPYRIDIN-2-YLOXY-PHENYL AND THIAZOLOPYRAZIN-2-YLOXY-PHENYL AMINES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE
LIANG, JIMMY T, SANTILLAN, JR., ALEJANDRO, FOURIE, ANNE M, MANI, NEELAKANDA S, GOMEZ, LAURENT, TANIS, VIRGINIA M, GRICE, CHERYL A, CHROVIAN, CHRISTA C, KEARNEY, AARON M, BACANI, GENESIS M, LOCHNER, SUSANNE, SEPASSI, KIA, LEE-DUTRA, ALICE, LANDRY-BAYLE, ADRIENNE M, BROGGINI, DIEGO, WIENER, JOHN J. M, ZINSER, HARTMUT, CHEUNG, EUGENE Y, XIAOHU, DENG, SAPPEY, KATHLEEN C, WICKBOLDT, ALVAH T
Year of Publication 30.06.2016
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Year of Publication 30.06.2016
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Process for the preparation of histamine H3 receptor modulators
MANI, NEELAKANDHA S, BROGGINI, DIEGO, LELLEK, VIT, MAURER, ADRIAN, LOCHNER, SUSANNE, YOUNG, LANA, PIPPEL, DANIEL J
Year of Publication 13.10.2011
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Year of Publication 13.10.2011
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CRYSTALLINE HEMI-TARTRATE OF [5-(4,6-DIMETHYL-1H-BENZOIMIDAZOL-2-YL)-4-METHYL-PYRIMIDIN-2-YL]-4-METHYL-PYRIMIDIN-2-YL]-[3-(1-METHYL-PIPERIDIN-4-YL)-PROPYL]-AMINE
CESCO-CANCIAN SERGIO, DIEGO BROGGINI, LOCHNER SUSANNE, XIAO TONG, GRIMM JEFFREY S, PIPPEL DANIEL J, MAPES CHRISTOPHER M, NEELAKANDHA S MANI, DAVID C PALMER
Year of Publication 06.03.2014
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Year of Publication 06.03.2014
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