Development of SYN-004, an oral beta-lactamase treatment to protect the gut microbiome from antibiotic-mediated damage and prevent Clostridium difficile infection
Kaleko, Michael, Bristol, J. Andrew, Hubert, Steven, Parsley, Todd, Widmer, Giovanni, Tzipori, Saul, Subramanian, Poorani, Hasan, Nur, Koski, Perrti, Kokai-Kun, John, Sliman, Joseph, Jones, Annie, Connelly, Sheila
Published in Anaerobe (01.10.2016)
Published in Anaerobe (01.10.2016)
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Preclinical Characterization of a Novel Monoclonal Antibody NEO-201 for the Treatment of Human Carcinomas
Fantini, Massimo, David, Justin M, Saric, Olga, Dubeykovskiy, Alexander, Cui, Yongzhi, Mavroukakis, Sharon A, Bristol, Andrew, Annunziata, Christina M, Tsang, Kwong Y, Arlen, Philip M
Published in Frontiers in immunology (04.01.2018)
Published in Frontiers in immunology (04.01.2018)
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Journal Article
Nonclinical Safety Assessment of SYN-004: An Oral β-lactamase for the Protection of the Gut Microbiome From Disruption by Biliary-Excreted, Intravenously Administered Antibiotics
Kokai-Kun, John F, Bristol, J Andrew, Setser, John, Schlosser, Michael
Published in International journal of toxicology (01.05.2016)
Published in International journal of toxicology (01.05.2016)
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Journal Article
Tolerability and Pharmacokinetics of SYN-004, an Orally Administered β-Lactamase for the Prevention of Clostridium difficile-Associated Disease and Antibiotic-Associated Diarrhea, in Two Phase 1 Studies
Roberts, Tracey, Kokai-Kun, John F., Coughlin, Olivia, Lopez, Barbara Valero, Whalen, Heidi, Bristol, J. Andrew, Hubert, Steven, Longstreth, James, Lasseter, Kenneth, Sliman, Joseph
Published in Clinical drug investigation (01.09.2016)
Published in Clinical drug investigation (01.09.2016)
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Journal Article
Formulation development of SYN-004 (ribaxamase) oral solid dosage form, a β-lactamase to prevent intravenous antibiotic-associated dysbiosis of the colon
Bristol, Andrew, Hubert, Steven, Hofmann, Felix, Baer, Hans
Published in International journal of pharmaceutics (20.12.2017)
Published in International journal of pharmaceutics (20.12.2017)
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Journal Article
Development of a Modified-Release Formulation of Lovastatin Targeted to Intestinal Methanogens Implicated in Irritable Bowel Syndrome With Constipation
Hubert, Steven, Chadwick, Alan, Wacher, Vince, Coughlin, Olivia, Kokai-Kun, John, Bristol, Andrew
Published in Journal of pharmaceutical sciences (01.02.2018)
Published in Journal of pharmaceutical sciences (01.02.2018)
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Journal Article
Potentiation of oncolytic adenoviral vector efficacy with gutless vectors encoding GMCSF or TRAIL
Burroughs, Kevin D, Kayda, Dawn B, Sakhuja, Kiran, Hudson, Yvette, Jakubczak, John, Bristol, J Andrew, Ennist, David, Hallenbeck, Paul, Kaleko, Michael, Connelly, Sheila
Published in Cancer gene therapy (01.02.2004)
Published in Cancer gene therapy (01.02.2004)
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Journal Article
알칼리성 포스파타제 제형 및 이의 용도
FREIRE CRISTINA, KALEKO MICHAEL, STAPLETON RAY, BRISTOL ANDREW, HUBERT STEVEN
Year of Publication 08.02.2022
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Year of Publication 08.02.2022
Patent
In vitro and in vivo activities of an oncolytic adenoviral vector designed to express GM-CSF
Bristol, J.Andrew, Zhu, Mingzhu, Ji, Hong, Mina, Mervat, Xie, Yuefeng, Clarke, Lori, Forry-Schaudies, Suzanne, Ennist, David L
Published in Molecular therapy (01.06.2003)
Published in Molecular therapy (01.06.2003)
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Journal Article
Anti-tumor activity of a novel monoclonal antibody, NPC-1C, optimized for recognition of tumor antigen MUC5AC variant in preclinical models
Patel, Sandip Pravin, Bristol, Andrew, Saric, Olga, Wang, Xue-Ping, Dubeykovskiy, Alex, Arlen, Philip M., Morse, Michael A.
Published in Cancer Immunology, Immunotherapy (01.06.2013)
Published in Cancer Immunology, Immunotherapy (01.06.2013)
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Journal Article
Abstract C14: Tissue expression profile of novel tumor biomarkers identified by monoclonal antibodies
Arlen, Philip M., Saric, Olga, Arlen, Myron, Bristol, Andrew
Published in Molecular cancer therapeutics (12.11.2011)
Published in Molecular cancer therapeutics (12.11.2011)
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