Selective activation of apoptosis by a novel set of 4-aryl-3-(3-aryl-1-oxo-2-propenyl)-2( 1H )-quinolinones through a Myc-dependent pathway
Claassen, Gisela, Brin, Elena, Crogan-Grundy, Candace, Vaillancourt, Mei Ting, Zhang, Han Zhong, Cai, Sui Xiong, Drewe, John, Tseng, Ben, Kasibhatla, Shailaja
Published in Cancer letters (18.02.2009)
Published in Cancer letters (18.02.2009)
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Journal Article
Modeling the Late Steps in HIV-1 Retroviral Integrase-catalyzed DNA Integration
Brin, Elena, Yi, Jizu, Skalka, Anna Marie, Leis, Jonathan
Published in The Journal of biological chemistry (15.12.2000)
Published in The Journal of biological chemistry (15.12.2000)
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Journal Article
PEGylated arginine deiminase can modulate tumor immune microenvironment by affecting immune checkpoint expression, decreasing regulatory T cell accumulation and inducing tumor T cell infiltration
Brin, Elena, Wu, Katherine, Lu, Hsin-Tze, He, Yudou, Dai, Zhaoming, He, Wei
Published in Oncotarget (29.08.2017)
Published in Oncotarget (29.08.2017)
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Journal Article
Abstract 3902: A novel biologic ADI-TRAIL fusion protein benefits from structural and functional complementarity of its components arginine deiminase and TRAIL, induces cancer cell apoptosis in vitro, and inhibits tumor growth in vivo
Brin, Elena, Wu, Katherine, He, Yudou, Shia, Wei-Jong, Kuo, Mario M., Chen, Li-Chang, Dagostino, Eleanor, Hickey, Richard, Almassy, Bob, Showalter, Richard, Thomson, Jim
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
TRAIL stabilization and cancer cell sensitization to its pro-apoptotic activity achieved through genetic fusion with arginine deiminase
Brin, Elena, Wu, Katherine, Dagostino, Eleanor, Meng-Chiang Kuo, Mario, He, Yudou, Shia, Wei-Jong, Chen, Li-Chang, Stempniak, Mariusz, Hickey, Richard, Almassy, Robert, Showalter, Richard, Thomson, James
Published in Oncotarget (11.12.2018)
Published in Oncotarget (11.12.2018)
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Journal Article
Abstract LB-20: PEGylated TRAIL/Apo2L shows greatly improved circulating half life and improved anti-tumor efficacy in xenograft models for colon and pancreatic cancer
Biroc, Sandra L., Brin, Elena, Knudsen, Nick, Marsden, Robin, de Dios, Kristine, Hewet, Amha G., Pinkstaff, Jason, Kraynov, Vadim
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Journal Article
Cancer-induced Expansion and Activation of CD11b+Gr-1+ Cells Predispose Mice to Adenoviral-triggered Anaphylactoid-type Reactions
Pande, Kalyan, Ueda, Roanna, Machemer, Todd, Sathe, Manjiri, Tsai, Van, Brin, Elena, Delano, Matthew J, Van Rooijen, Nico, McClanahan, Terrill K, Talmadge, James E, Moldawer, Lyle L, Phillips, Joseph H, LaFace, Drake M
Published in Molecular therapy (01.03.2009)
Published in Molecular therapy (01.03.2009)
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Characterization of Hemodynamic Events Following Intravascular Infusion of Recombinant Adenovirus Reveals Possible Solutions for Mitigating Cardiovascular Responses
Machemer, Todd, Engler, Heidrun, Tsai, Van, Lee, Seoju, Cannon-Carlson, Susan, Voloch, Marcio, Schluep, Thomas, Ravindran, Sundari, Vellekamp, Gary, Brin, Elena, Cornell, Douglas, Sutjipto, Suganto, Wen, Shu Fen, Horn, Mark, Van Rooijen, Nico, Maneval, Dan, Hutchins, Beth, LaFace, Drake
Published in Molecular therapy (01.08.2005)
Published in Molecular therapy (01.08.2005)
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