Discovery of LFF571: An Investigational Agent for Clostridium difficile Infection
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Published in Journal of medicinal chemistry (08.03.2012)
Published in Journal of medicinal chemistry (08.03.2012)
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De Novo Design, Synthesis, and Biological Evaluation of 3,4-Disubstituted Pyrrolidine Sulfonamides as Potent and Selective Glycine Transporter 1 Competitive Inhibitors
Wang, Ying, Zhao, Hongyu, Brewer, Jason T, Li, Huanqiu, Lao, Yanbin, Amberg, Willi, Behl, Berthold, Akritopoulou-Zanze, Irini, Dietrich, Justin, Lange, Udo E. W, Pohlki, Frauke, Hoft, Carolin, Hornberger, Wilfried, Djuric, Stevan W, Sydor, Jens, Mezler, Mario, Relo, Ana Lucia, Vasudevan, Anil
Published in Journal of medicinal chemistry (13.09.2018)
Published in Journal of medicinal chemistry (13.09.2018)
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Fragment-Based Discovery of an Apolipoprotein E4 (apoE4) Stabilizer
Petros, Andrew M, Korepanova, Alla, Jakob, Clarissa G, Qiu, Wei, Panchal, Sanjay C, Wang, Jie, Dietrich, Justin D, Brewer, Jason T, Pohlki, Frauke, Kling, Andreas, Wilcox, Kyle, Lakics, Viktor, Bahnassawy, Lamiaa, Reinhardt, Peter, Partha, Sarathy Karunan, Bodelle, Pierre M, Lake, Marc, Charych, Erik I, Stoll, Vincent S, Sun, Chaohong, Mohler, Eric G
Published in Journal of medicinal chemistry (25.04.2019)
Published in Journal of medicinal chemistry (25.04.2019)
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Discovery of Novel Aminotetralines and Aminochromanes as Selective and Competitive Glycine Transporter 1 (GlyT1) Inhibitors
Amberg, Willi, Lange, Udo E. W, Ochse, Michael, Pohlki, Frauke, Behl, Berthold, Relo, Ana Lucia, Hornberger, Wilfried, Hoft, Carolin, Mezler, Mario, Sydor, Jens, Wang, Ying, Zhao, Hongyu, Brewer, Jason T, Dietrich, Justin, Li, Huanqiu, Akritopoulou-Zanze, Irini, Lao, Yanbin, Hannick, Steven M, Ku, Yi-Yin, Vasudevan, Anil
Published in Journal of medicinal chemistry (13.09.2018)
Published in Journal of medicinal chemistry (13.09.2018)
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Journal Article
Discovery of diamide compounds as diacylglycerol acyltransferase 1 (DGAT1) inhibitors
Nakajima, Katsumasa, April, Myriam, Brewer, Jason T., Daniels, Thomas, Forster, Cornelia J., Gilmore, Thomas A., Jain, Monish, Kanter, Aaron, Kwak, Youngshin, Li, Jingzhou, McQuire, Les, Serrano-Wu, Michael H., Streeper, Ryan, Szklennik, Paul, Thompson, James, Wang, Bing
Published in Bioorganic & medicinal chemistry letters (15.02.2016)
Published in Bioorganic & medicinal chemistry letters (15.02.2016)
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Journal Article
Antibacterial Optimization of 4-Aminothiazolyl Analogues of the Natural Product GE2270 A: Identification of the Cycloalkylcarboxylic Acids
LaMarche, Matthew J, Leeds, Jennifer A, Amaral, Kerri, Brewer, Jason T, Bushell, Simon M, Dewhurst, Janetta M, Dzink-Fox, JoAnne, Gangl, Eric, Goldovitz, Julie, Jain, Akash, Mullin, Steve, Neckermann, Georg, Osborne, Colin, Palestrant, Deborah, Patane, Michael A, Rann, Elin M, Sachdeva, Meena, Shao, Jian, Tiamfook, Stacey, Whitehead, Lewis, Yu, Donghui
Published in Journal of medicinal chemistry (08.12.2011)
Published in Journal of medicinal chemistry (08.12.2011)
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4,5-DIHYDROPYRAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY
ZHAO, Hongyu, AMBERG, Wilhelm, WANG, Ying, LAO, Yanbin, BREWER, Jason T, HUTCHINS, Charles, POHLKI, Frauke, LANGE, Udo, VASUDEVAN, Anil, LI, Huan-Qiu
Year of Publication 11.03.2020
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Year of Publication 11.03.2020
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MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF
Relo, Ana-Lucia, Djuric, Stevan W, Pohlki, Frauke, Brewer, Jason T, Akritopoulou-Zanze, Irini, Wang, Ying, Shelat, Bhadra, Braje, Wilfried
Year of Publication 10.05.2018
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Year of Publication 10.05.2018
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MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF
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Year of Publication 20.03.2018
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Year of Publication 20.03.2018
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Modulators of 5-HT receptors and methods of use thereof
Djuric Stevan W, Wang Ying, Relo Ana-Lucia, Shelat Bhadra, Pohlki Frauke, Braje Wilfried, Akritopoulou-Zanze Irini, Brewer Jason T
Year of Publication 11.07.2017
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Year of Publication 11.07.2017
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PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY
AMBERG, Wilhelm, HUTCHINS, Charles W, ZHAO, Hongyu H, BREWER, Jason T, POHLKI, Frauke, VASUDEVAN, Anil, LI, Huan-Qiu, WANG, Ying X, ZANZE, Irini, LAO, Yanbin, DIETRICH, Justin, DJURIC, Stevan, W, LANGE, Udo
Year of Publication 17.04.2019
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Year of Publication 17.04.2019
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MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF
AKRITOPOULOU-ZANZE, Irini, WANG, Ying, DJURIC, Stevan, W, BREWER, Jason, T, POHLKI, Frauke, BRAJE, Wilfried, RELO, Ana-Lucia
Year of Publication 05.04.2017
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Year of Publication 05.04.2017
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BENZODIAZEPINE AND PYRIDODIAZEPINE DERIVATIVES
WANG YING, AKRITOPOULOU-ZANZE IRINI, SCANIO MARC, BUNNELLE WILLIAM H, BREWER JASON T
Year of Publication 25.02.2016
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Year of Publication 25.02.2016
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MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF
BREWER, JASON, T, BRAJE, WILFRIED, AKRITOPOULOU-ZANZE, IRINI, RELO, ANA-LUCIA, POHLKI, FRAUKE, WANG, YING, DJURIC, STEVAN, W
Year of Publication 16.11.2016
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Year of Publication 16.11.2016
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Benzodiazepine and pyridodiazepine derivatives
WANG YING, AKRITOPOULOU-ZANZE IRINI, SCANIO MARC, BUNNELLE WILLIAM H, BREWER JASON T
Year of Publication 15.09.2015
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Year of Publication 15.09.2015
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4,5-DIHYDROPYRAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY
ZHAO, Hongyu, AMBERG, Wilhelm, WANG, Ying, LAO, Yanbin, BREWER, Jason T, HUTCHINS, Charles, POHLKI, Frauke, LANGE, Udo, VASUDEVAN, Anil, LI, Huan-Qiu
Year of Publication 19.07.2017
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Year of Publication 19.07.2017
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MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF
BREWER, JASON, T, BRAJE, WILFRIED, AKRITOPOULOU-ZANZE, IRINI, RELO, ANA-LUCIA, POHLKI, FRAUKE, WANG, YING, DJURIC, STEVAN, W
Year of Publication 09.03.2016
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Year of Publication 09.03.2016
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Modulators of 5-HT receptors and methods of use thereof
BREWER, JASON, T, BRAJE, WILFRIED, AKRITOPOULOU-ZANZE, IRINI, RELO, ANA-LUCIA, POHLKI, FRAUKE, WANG, YING, DJURIC, STEVAN, W
Year of Publication 20.01.2016
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Year of Publication 20.01.2016
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BENZODIAZEPINE AND PYRIDODIAZEPINE DERIVATIVES
WANG YING, AKRITOPOULOU-ZANZE IRINI, SCANIO MARC, BUNNELLE WILLIAM H, BREWER JASON T
Year of Publication 12.06.2014
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Year of Publication 12.06.2014
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