The TNF Family of Ligands and Receptors: Communication Modules in the Immune System and Beyond
Dostert, Catherine, Grusdat, Melanie, Letellier, Elisabeth, Brenner, Dirk
Published in Physiological reviews (01.01.2019)
Published in Physiological reviews (01.01.2019)
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IL-17+ CD8+ T cell suppression by dimethyl fumarate associates with clinical response in multiple sclerosis
Lückel, Christina, Picard, Felix, Raifer, Hartmann, Campos Carrascosa, Lucia, Guralnik, Anna, Zhang, Yajuan, Klein, Matthias, Bittner, Stefan, Steffen, Falk, Moos, Sonja, Marini, Federico, Gloury, Renee, Kurschus, Florian C., Chao, Ying-Yin, Bertrams, Wilhelm, Sexl, Veronika, Schmeck, Bernd, Bonetti, Lynn, Grusdat, Melanie, Lohoff, Michael, Zielinski, Christina E., Zipp, Frauke, Kallies, Axel, Brenner, Dirk, Berger, Michael, Bopp, Tobias, Tackenberg, Björn, Huber, Magdalena
Published in Nature communications (16.12.2019)
Published in Nature communications (16.12.2019)
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IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
Sasaki, Masato, Knobbe, Christiane B., Munger, Joshua C., Lind, Evan F., Brenner, Dirk, Brüstle, Anne, Harris, Isaac S., Holmes, Roxanne, Wakeham, Andrew, Haight, Jillian, You-Ten, Annick, Li, Wanda Y., Schalm, Stefanie, Su, Shinsan M., Virtanen, Carl, Reifenberger, Guido, Ohashi, Pamela S., Barber, Dwayne L., Figueroa, Maria E., Melnick, Ari, Zúñiga-Pflücker, Juan-Carlos, Mak, Tak W.
Published in Nature (London) (30.08.2012)
Published in Nature (London) (30.08.2012)
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Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis
Kiweler, Nicole, Delbrouck, Catherine, Pozdeev, Vitaly I., Neises, Laura, Soriano-Baguet, Leticia, Eiden, Kim, Xian, Feng, Benzarti, Mohaned, Haase, Lara, Koncina, Eric, Schmoetten, Maryse, Jaeger, Christian, Noman, Muhammad Zaeem, Vazquez, Alexei, Janji, Bassam, Dittmar, Gunnar, Brenner, Dirk, Letellier, Elisabeth, Meiser, Johannes
Published in Nature communications (16.05.2022)
Published in Nature communications (16.05.2022)
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Lymphocyte-derived ACh regulates local innate but not adaptive immunity
Reardon, Colin, Duncan, Gordon S., Brüstle, Anne, Brenner, Dirk, Tusche, Michael W., Olofsson, Peder, Rosas-Ballina, Mauricio, Tracey, Kevin J., Mak, Tak W.
Published in Proceedings of the National Academy of Sciences - PNAS (22.01.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (22.01.2013)
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Deprivation of dietary fiber in specific-pathogen-free mice promotes susceptibility to the intestinal mucosal pathogen Citrobacter rodentium
Neumann, Mareike, Steimle, Alex, Grant, Erica T., Wolter, Mathis, Parrish, Amy, Willieme, Stéphanie, Brenner, Dirk, Martens, Eric C., Desai, Mahesh S.
Published in Gut microbes (01.01.2021)
Published in Gut microbes (01.01.2021)
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Glutathione-dependent redox balance characterizes the distinct metabolic properties of follicular and marginal zone B cells
Franchina, Davide G., Kurniawan, Henry, Grusdat, Melanie, Binsfeld, Carole, Guerra, Luana, Bonetti, Lynn, Soriano-Baguet, Leticia, Ewen, Anouk, Kobayashi, Takumi, Farinelle, Sophie, Minafra, Anna Rita, Vandamme, Niels, Carpentier, Anaïs, Borgmann, Felix K., Jäger, Christian, Chen, Ying, Kleinewietfeld, Markus, Vasiliou, Vasilis, Mittelbronn, Michel, Hiller, Karsten, Lang, Philipp A., Brenner, Dirk
Published in Nature communications (04.04.2022)
Published in Nature communications (04.04.2022)
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High Glucose Enhances Cytotoxic T Lymphocyte-Mediated Cytotoxicity
Zhu, Jie, Yang, Wenjuan, Zhou, Xiangda, Zöphel, Dorina, Soriano-Baguet, Leticia, Dolgener, Denise, Carlein, Christopher, Hof, Chantal, Zhao, Renping, Ye, Shandong, Schwarz, Eva C, Brenner, Dirk, Prates Roma, Leticia, Qu, Bin
Published in Frontiers in immunology (25.06.2021)
Published in Frontiers in immunology (25.06.2021)
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Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions
Soriano-Baguet, Leticia, Grusdat, Melanie, Kurniawan, Henry, Benzarti, Mohaned, Binsfeld, Carole, Ewen, Anouk, Longworth, Joseph, Bonetti, Lynn, Guerra, Luana, Franchina, Davide G., Kobayashi, Takumi, Horkova, Veronika, Verschueren, Charlène, Helgueta, Sergio, Gérard, Deborah, More, Tushar H., Henne, Antonia, Dostert, Catherine, Farinelle, Sophie, Lesur, Antoine, Gérardy, Jean-Jacques, Jäger, Christian, Mittelbronn, Michel, Sinkkonen, Lasse, Hiller, Karsten, Meiser, Johannes, Brenner, Dirk
Published in Cell reports (Cambridge) (28.03.2023)
Published in Cell reports (Cambridge) (28.03.2023)
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Glutathione synthesis in the mouse liver supports lipid abundance through NRF2 repression
Asantewaa, Gloria, Tuttle, Emily T., Ward, Nathan P., Kang, Yun Pyo, Kim, Yumi, Kavanagh, Madeline E., Girnius, Nomeda, Chen, Ying, Rodriguez, Katherine, Hecht, Fabio, Zocchi, Marco, Smorodintsev-Schiller, Leonid, Scales, TashJaé Q., Taylor, Kira, Alimohammadi, Fatemeh, Duncan, Renae P., Sechrist, Zachary R., Agostini-Vulaj, Diana, Schafer, Xenia L., Chang, Hayley, Smith, Zachary R., O’Connor, Thomas N., Whelan, Sarah, Selfors, Laura M., Crowdis, Jett, Gray, G. Kenneth, Bronson, Roderick T., Brenner, Dirk, Rufini, Alessandro, Dirksen, Robert T., Hezel, Aram F., Huber, Aaron R., Munger, Joshua, Cravatt, Benjamin F., Vasiliou, Vasilis, Cole, Calvin L., DeNicola, Gina M., Harris, Isaac S.
Published in Nature communications (21.07.2024)
Published in Nature communications (21.07.2024)
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c-FLIPR, a New Regulator of Death Receptor-induced Apoptosis
Golks, Alexander, Brenner, Dirk, Fritsch, Cornelius, Krammer, Peter H., Lavrik, Inna N.
Published in The Journal of biological chemistry (15.04.2005)
Published in The Journal of biological chemistry (15.04.2005)
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K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression
Hao, Zhenyue, Sheng, Yi, Duncan, Gordon S., Li, Wanda Y., Dominguez, Carmen, Sylvester, Jennifer, Su, Yu-Wen, Lin, Gloria H.Y., Snow, Bryan E., Brenner, Dirk, You-Ten, Annick, Haight, Jillian, Inoue, Satoshi, Wakeham, Andrew, Elford, Alisha, Hamilton, Sara, Liang, Yi, Zúñiga-Pflücker, Juan C., He, Housheng Hansen, Ohashi, Pamela S., Mak, Tak W.
Published in Nature communications (13.01.2017)
Published in Nature communications (13.01.2017)
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2-Methoxyestradiol inhibits experimental autoimmune encephalomyelitis through suppression of immune cell activation
Duncan, Gordon S., Brenner, Dirk, Tusche, Michael W., Brüstle, Anne, Knobbe, Christiane B., Elia, Andrew J., Mock, Thomas, Bray, Mark R., Krammer, Peter H., Mak, Tak W.
Published in Proceedings of the National Academy of Sciences - PNAS (18.12.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (18.12.2012)
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Toso controls encephalitogenic immune responses by dendritic cells and regulatory T cells
Brenner, Dirk, Brüstle, Anne, Lin, Gloria H. Y., Lang, Philipp A., Duncan, Gordon S., Knobbe-Thomsen, Christiane B., Paul, Michael St, Reardon, Colin, Tusche, Michael W., Snow, Bryan, Hamilton, Sara R., Pfefferle, Aline, Gilani, Syed O., Ohashi, Pamela S., Lang, Karl S., Mak, Tak W.
Published in Proceedings of the National Academy of Sciences - PNAS (21.01.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (21.01.2014)
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Unspecific CTL Killing Is Enhanced by High Glucose via TNF-Related Apoptosis-Inducing Ligand
Yang, Wenjuan, Denger, Andreas, Diener, Caroline, Küppers, Frederic, Soriano-Baguet, Leticia, Schäfer, Gertrud, Yanamandra, Archana K, Zhao, Renping, Knörck, Arne, Schwarz, Eva C, Hart, Martin, Lammert, Frank, Roma, Leticia Prates, Brenner, Dirk, Christidis, Grigorios, Helms, Volkhard, Meese, Eckart, Hoth, Markus, Qu, Bin
Published in Frontiers in immunology (21.02.2022)
Published in Frontiers in immunology (21.02.2022)
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The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis
Hao, Zhenyue, Duncan, Gordon S, Su, Yu-Wen, Li, Wanda Y, Silvester, Jennifer, Hong, Claire, You, Han, Brenner, Dirk, Gorrini, Chiara, Haight, Jillian, Wakeham, Andrew, You-Ten, Annick, McCracken, Susan, Elia, Andrew, Li, Qinxi, Detmar, Jacqui, Jurisicova, Andrea, Hobeika, Elias, Reth, Michael, Sheng, Yi, Lang, Philipp A, Ohashi, Pamela S, Zhong, Qing, Wang, Xiaodong, Mak, Tak W
Published in The Journal of experimental medicine (16.01.2012)
Published in The Journal of experimental medicine (16.01.2012)
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Autophagy-independent functions of UVRAG are essential for peripheral naive T-cell homeostasis
Afzal, Samia, Hao, Zhenyue, Itsumi, Momoe, Abouelkheer, Yasser, Brenner, Dirk, Gao, Yunfei, Wakeham, Andrew, Hong, Claire, Li, Wanda Y., Sylvester, Jennifer, Gilani, Syed O., Brüstle, Anne, Haight, Jillian, You-Ten, Annick J., Lin, Gloria H. Y., Inoue, Satoshi, Mak, Tak W.
Published in Proceedings of the National Academy of Sciences - PNAS (27.01.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (27.01.2015)
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Phosphorylation of CARMA1 by HPK1 is critical for NF-κB activation in T cells
Brenner, Dirk, Brechmann, Markus, Röhling, Simone, Tapernoux, Myriam, Mock, Thomas, Winter, Dominic, Lehmann, Wolf D, Kiefer, Friedemann, Thome, Margot, Krammer, Peter H, Arnold, Rüdiger
Published in Proceedings of the National Academy of Sciences - PNAS (25.08.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (25.08.2009)
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HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1
Quintela-Fandino, Miguel, Arpaia, Enrico, Brenner, Dirk, Goh, Theo, Yeung, Faith Au, Blaser, Heiko, Alexandrova, Roumiana, Lind, Evan F, Tusche, Mike W, Wakeham, Andrew, Ohashi, Pamela S, Mak, Tak W
Published in Proceedings of the National Academy of Sciences - PNAS (09.02.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (09.02.2010)
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Hepatocyte growth factor induces Mcl‐1 in primary human hepatocytes and inhibits CD95‐mediated apoptosis via Akt
Schulze‐Bergkamen, Henning, Brenner, Dirk, Krueger, Andreas, Suess, Dorothee, Fas, Stefanie C., Frey, Christian R., Dax, Andreas, Zink, Dorothea, Büchler, Peter, Müller, Martina, Krammer, Peter H.
Published in Hepatology (Baltimore, Md.) (01.03.2004)
Published in Hepatology (Baltimore, Md.) (01.03.2004)
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