Partial synthesis of 14-deoxy-14-aminotriptolide
Kaloun, El Bachir, Long, Christophe, Molinier, Nicolas, Brel, Viviane, Cantagrel, Frédéric, Massiot, Georges
Published in Tetrahedron letters (27.04.2016)
Published in Tetrahedron letters (27.04.2016)
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Semisynthetic neoboutomellerone derivatives as ubiquitin-proteasome pathway inhibitors
Beck, Joséphine, Guminski, Yves, Long, Christophe, Marcourt, Laurence, Derguini, Fadila, Plisson, Fabien, Grondin, Antonio, Vandenberghe, Isabelle, Vispé, Stéphane, Brel, Viviane, Aussagues, Yannick, Ausseil, Frédéric, Arimondo, Paola B., Massiot, Georges, Sautel, François, Cantagrel, Frédéric
Published in Bioorganic & medicinal chemistry (15.01.2012)
Published in Bioorganic & medicinal chemistry (15.01.2012)
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Abstract 6425: Sensitivity of oncogenic KRAS-expressing cells to CDK9 inhibition identified by a phenotypic compound screen
Lai, Lick P., Brel, Viviane, Sharma, Kanika, Frappier, Julia, Le-Henanf, Nadia, Vivet, Bertrand, Muzet, Nicolas, Schell, Emilie, Morales, Renaud, Rooney, Eamonn, Holderfield, Matthew, Lacroix, Frederic, Englaro, Walter, Marcireau, Christophe, Debussche, Laurent, Nissley, Dwight V., Mccormick, Frank
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Cytotoxicity and cell death mechanisms induced by the polyamine-vectorized anti-cancer drug F14512 targeting topoisomerase II
Brel, Viviane, Annereau, Jean-Philippe, Vispé, Stéphane, Kruczynski, Anna, Bailly, Christian, Guilbaud, Nicolas
Published in Biochemical pharmacology (15.12.2011)
Published in Biochemical pharmacology (15.12.2011)
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Phase I Clinical Pharmacology Study of F14512, a New Polyamine-Vectorized Anticancer Drug, in Naturally Occurring Canine Lymphoma
Tierny, Dominique, Serres, François, Segaoula, Zacharie, Bemelmans, Ingrid, Bouchaert, Emmanuel, Pétain, Aurélie, Brel, Viviane, Couffin, Stéphane, Marchal, Thierry, Nguyen, Laurent, Thuru, Xavier, Ferré, Pierre, Guilbaud, Nicolas, Gomes, Bruno
Published in Clinical cancer research (01.12.2015)
Published in Clinical cancer research (01.12.2015)
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F14512, a potent antitumor agent targeting topoisomerase II vectored into cancer cells via the polyamine transport system
Barret, Jean-Marc, Kruczynski, Anna, Vispé, Stéphane, Annereau, Jean-Philippe, Brel, Viviane, Guminski, Yves, Delcros, Jean-Guy, Lansiaux, Amélie, Guilbaud, Nicolas, Imbert, Thierry, Bailly, Christian
Published in Cancer research (Chicago, Ill.) (01.12.2008)
Published in Cancer research (Chicago, Ill.) (01.12.2008)
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Sensitivity of Oncogenic KRAS-Expressing Cells to CDK9 Inhibition
Lai, Lick Pui, Brel, Viviane, Sharma, Kanika, Frappier, Julia, Le-Henanf, Nadia, Vivet, Bertrand, Muzet, Nicolas, Schell, Emilie, Morales, Renaud, Rooney, Eamonn, Basse, Nicolas, Yi, Ming, Lacroix, Frederic, Holderfield, Matthew, Englaro, Walter, Marcireau, Christophe, Debussche, Laurent, Nissley, Dwight V., McCormick, Frank
Published in SLAS discovery (01.08.2021)
Published in SLAS discovery (01.08.2021)
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Synthesis of conjugated spermine derivatives with 7-nitrobenzoxadiazole (NBD), rhodamine and bodipy as new fluorescent probes for the polyamine transport system
Guminski, Yves, Grousseaud, Martial, Cugnasse, Sandrine, Brel, Viviane, Annereau, Jean-Philippe, Vispé, Stéphane, Guilbaud, Nicolas, Barret, Jean-Marc, Bailly, Christian, Imbert, Thierry
Published in Bioorganic & medicinal chemistry letters (01.05.2009)
Published in Bioorganic & medicinal chemistry letters (01.05.2009)
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Abstract 5565: Tumor targeting and enhanced efficacy of novel polyamine-cytotoxic conjugates
Liéby-Muller, Frédéric, Annereau, Jean-Philippe, Brel, Viviane, Marion, Frédéric, Guminski, Yves, Redoules, Florence, de Saint Jores, Nathalie, André, Karine, Kruczynski, Anna, Bailly, Christian, Guilbaud, Nicolas
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Abstract 988: F14512, a novel vectorized topoiserase II inhibitor, bypasses MDR1 mediated resistance
Annereau, Jean Philippe, Brel, Viviane, Riquet, William, Créancier, Laurent, Vandenberghe, Isabelle, Fournier, Emmanuel, Robichon, Céline, Stennevin, Aline, Offrete, Vanessa, Lacastaigneratte, Laurence, Gomes, Bruno, Kruczynski, Anna, Bailly, Christian, Guilbaud, Nicolas
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Abstract B37: F14512, a polyamine-vectorized anticancer drug, triggers senescence cell death mechanism
Brel, Viviane, Annereau, J-Philippe, Gomes, Bruno, Vandenberghe, Isabelle, Andre, Karine, Marionneau, Marie-Laure, Lacastaigneratte, Laurence, Stennevin, Aline, Rouquet, Jerome, Latil, Alain, Kruczynski, Anna, Bailly, Christian, Guilbaud, Nicolas
Published in Molecular cancer therapeutics (12.11.2011)
Published in Molecular cancer therapeutics (12.11.2011)
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Abstract A51: Antiproliferative activity of F14512, a novel polyamine-vectorized drug, on multidrug resistant cancer cells
Créancier, Laurent, Guilbaud, Nicolas, Annereau, Jean-Philippe, Brel, Viviane, Marionneau-Brossard, Marie-Laure, Offrete, Vanessa, Verdier, Jérôme, André, Karine, Fournier, Emmanuel, Guminski, Yves, Kruczynski, Anna
Published in Clinical cancer research (15.05.2012)
Published in Clinical cancer research (15.05.2012)
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Abstract 1925: Trifluoromethylated artemisinin dimers demonstrate a potent anti-cancer activity in vitro and in vivo
Fahy, Jacques, Marion, Frederic, Lieby-Muller, Frederic, Mordant, Celine, Vispe, Stephane, Brel, Viviane, Gomes, Bruno, Annereau, Jean-Philippe, Chollet, Constance, Fournial, Anaïs, Crousse, Benoit, Bonnet-Delpon, Daniele, Kruczynski, Anna, Bailly, Christian, Guilbaud, Nicolas
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Semisynthetic neoboutomellerone derivatives as ubiquitin-proteasome pathway inhibitors: Symposium-in-Print: Chemical Proteomics
BECK, Joséphine, GUMINSKI, Yves, AUSSAGUES, Yannick, AUSSEIL, Frédéric, ARIMONDO, Paola B, MASSIOT, Georges, SAUTEL, François, CANTAGREL, Frederic, LONG, Christophe, MARCOURT, Laurence, DERGUINI, Fadila, PLISSON, Fabien, GRONDIN, Antonio, VANDENBERGHE, Isabelle, VISPE, Stephane, BREL, Viviane
Published in Bioorganic & medicinal chemistry (2012)
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Published in Bioorganic & medicinal chemistry (2012)
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Abstract 3518: In vitro and in vivo synergistic effects of F14512, a novel targeted cytotoxic agent in phase I clinical study, in combination with other anticancer drugs
Vandenberghe, Isabelle, Annereau, Jean-Philippe, Brel, Viviane, Vispe, Stéphane, Barret, Jean-Marc, GOMES, Bruno, Offrete, Vanessa, Andre, Karine, Roy, Sabine, Castano, Caroline, Celestin, Fiona, Guminski, Yves, Imbert, Thierry, Kruczynski, Anna, Guilbaud, Nicolas, Bailly, Christian
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Abstract 2747: Synergistic antileukemic activity of F14512 in combination with AraC
Vandenberghe-Huez, Isabelle, Pillon, Arnaud, Créancier, Laurent, Gomes, Bruno, Annereau, Jean-Philippe, Fournier, Emmanuel, Brel, Viviane, Cartron, Valérie, Chansard, Nathalie, Pourtau, Sandrine, Roy, Sabine, Blanchet, Jean-Christophe, Verdier, Jérôme, Dejean, Caroline, Ricome, Christel, Offrete, Vanessa, Gras, Stéphane, André, Karine, Guminski, Yves, Bailly, Christian, Guilbaud, Nicolas, Kruczynski, Anna
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Antitumor activity of pyridoisoquinoline derivatives F91873 and F91874, novel multikinase inhibitors with activity against the anaplastic lymphoma kinase
Kruczynski, Anna, Mayer, Patrice, Marchand, Arnaud, Vispé, Stéphane, Fournier, Emmanuel, Annereau, Jean-Philippe, Brel, Viviane, Barret, Jean-Marc, Delsol, Georges, Imbert, Thierry, Fahy, Jacques, Bailly, Christian
Published in Anti-cancer drugs (01.06.2009)
Published in Anti-cancer drugs (01.06.2009)
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