Design and synthesis of vidarabine prodrugs as antiviral agents
Shen, Wei, Kim, Jae-Seung, Kish, Phillip E., Zhang, Jie, Mitchell, Stefanie, Gentry, Brian G., Breitenbach, Julie M., Drach, John C., Hilfinger, John
Published in Bioorganic & medicinal chemistry letters (01.02.2009)
Published in Bioorganic & medicinal chemistry letters (01.02.2009)
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Journal Article
Synthesis and biological activation of an ethylene glycol-linked amino acid conjugate of cyclic cidofovir
Eriksson, Ulrika, Hilfinger, John M., Kim, Jae-Seung, Mitchell, Stefanie, Kijek, Paul, Borysko, Katherine Z., Breitenbach, Julie M., Drach, John C., Kashemirov, Boris A., McKenna, Charles E.
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
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Amino Acid Ester Prodrugs of 2-Bromo-5,6-dichloro-1-(β-d-ribofuranosyl)benzimidazole Enhance Metabolic Stability in Vitro and in Vivo
Lorenzi, Philip L, Landowski, Christopher P, Song, Xueqin, Borysko, Katherine Z, Breitenbach, Julie M, Kim, Jae Seung, Hilfinger, John M, Townsend, Leroy B, Drach, John C, Amidon, Gordon L
Published in The Journal of pharmacology and experimental therapeutics (01.08.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2005)
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Tyrosine-Based 1-(S)-[3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine and -adenine ((S)-HPMPC and (S)-HPMPA) Prodrugs: Synthesis, Stability, Antiviral Activity, and in Vivo Transport Studies
Zakharova, Valeria M, Serpi, Michaela, Krylov, Ivan S, Peterson, Larryn W, Breitenbach, Julie M, Borysko, Katherine Z, Drach, John C, Collins, Mindy, Hilfinger, John M, Kashemirov, Boris A, McKenna, Charles E
Published in Journal of medicinal chemistry (25.08.2011)
Published in Journal of medicinal chemistry (25.08.2011)
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Journal Article
Inhibition of Cyclin-Dependent Kinase 1 by Purines and Pyrrolo[2,3-d]Pyrimidines Does Not Correlate with Antiviral Activity
EVERS, David L, BREITENBACH, Julie M, BORYSKO, Katherine Z, TOWNSEND, Leroy B, DRACHL, John C
Published in Antimicrobial Agents and Chemotherapy (01.08.2002)
Published in Antimicrobial Agents and Chemotherapy (01.08.2002)
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Journal Article
Human cytomegalovirus resistance to deoxyribosylindole nucleosides maps to a transversion mutation in the terminase subunit-encoding gene UL89
Gentry, Brian G, Phan, Quang, Hall, Ellie D, Breitenbach, Julie M, Borysko, Katherine Z, Kamil, Jeremy P, Townsend, Leroy B, Drach, John C
Published in Antimicrobial agents and chemotherapy (01.01.2015)
Published in Antimicrobial agents and chemotherapy (01.01.2015)
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Journal Article
Synthesis and Antiviral Activity of (Z)- and (E)-2,2-[Bis(hydroxymethyl)cyclopropylidene]methylpurines and -pyrimidines: Second-Generation Methylenecyclopropane Analogues of Nucleosides
Zhou, Shaoman, Breitenbach, Julie M, Borysko, Katherine Z, Drach, John C, Kern, Earl R, Gullen, Elizabeth, Cheng, Yung-Chi, Zemlicka, Jiri
Published in Journal of medicinal chemistry (29.01.2004)
Published in Journal of medicinal chemistry (29.01.2004)
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Journal Article
Benzimidazole Ribonucleosides: Design, Synthesis, and Antiviral Activity of Certain 2-(Alkylthio)- and 2-(Benzylthio)-5,6-dichloro-1-(.beta.-D-ribofuranosyl)benzimidazoles
Devivar, Rodrigo V, Kawashima, Etsuko, Revankar, Ganapathi R, Breitenbach, Julie M, Kreske, Edward D, Drach, John C, Townsend, Leroy B
Published in Journal of medicinal chemistry (01.09.1994)
Published in Journal of medicinal chemistry (01.09.1994)
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Journal Article
Serine Peptide Phosphoester Prodrugs of Cyclic Cidofovir: Synthesis, Transport, and Antiviral Activity
Eriksson, Ulrika, Peterson, Larryn W, Kashemirov, Boris A, Hilfinger, John M, Drach, John C, Borysko, Katherine Z, Breitenbach, Julie M, Kim, Jae Seung, Mitchell, Stefanie, Kijek, Paul, McKenna, Charles E
Published in Molecular pharmaceutics (01.07.2008)
Published in Molecular pharmaceutics (01.07.2008)
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Journal Article
(Z)- and (E)-2-((Hydroxymethyl)cyclopropylidene)methyladenine and -guanine. New Nucleoside Analogues with a Broad-Spectrum Antiviral Activity
Qiu, Yao-Ling, Ksebati, Mohamad B, Ptak, Roger G, Fan, Boreas Y, Breitenbach, Julie M, Lin, Ju-Sheng, Cheng, Yung-Chi, Kern, Earl R, Drach, John C, Zemlicka, Jiri
Published in Journal of medicinal chemistry (01.01.1998)
Published in Journal of medicinal chemistry (01.01.1998)
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Journal Article
(R)-(−)- and (S)-(+)-Synadenol: Synthesis, Absolute Configuration, and Enantioselectivity of Antiviral Effect
Qiu, Yao-Ling, Hempel, Andrew, Camerman, Norman, Camerman, Arthur, Geiser, Fiona, Ptak, Roger G, Breitenbach, Julie M, Kira, Toshiko, Li, Ling, Gullen, Elizabeth, Cheng, Yung-Chi, Drach, John C, Zemlicka, Jiri
Published in Journal of medicinal chemistry (17.12.1998)
Published in Journal of medicinal chemistry (17.12.1998)
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Journal Article
Deoxy Sugar Analogues of Triciribine: Correlation of Antiviral and Antiproliferative Activity with Intracellular Phosphorylation
Porcari, Anthony R, Ptak, Roger G, Borysko, Katherine Z, Breitenbach, Julie M, Vittori, Sauro, Wotring, Linda L, Drach, John C, Townsend, Leroy B
Published in Journal of medicinal chemistry (15.06.2000)
Published in Journal of medicinal chemistry (15.06.2000)
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Journal Article
Synthesis of Non-nucleoside Analogs of Toyocamycin, Sangivamycin, and Thiosangivamycin: The Effect of Certain 4- and 4,6-Substituents on the Antiviral Activity of Pyrrolo[2,3-d]pyrimidines
Renau, Thomas E, Kennedy, Christopher, Ptak, Roger G, Breitenbach, Julie M, Drach, John C, Townsend, Leroy B
Published in Journal of medicinal chemistry (30.08.1996)
Published in Journal of medicinal chemistry (30.08.1996)
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Journal Article
6-N-Acyltriciribine Analogues: Structure−Activity Relationship between Acyl Carbon Chain Length and Activity against HIV-1
Porcari, Anthony R, Ptak, Roger G, Borysko, Katherine Z, Breitenbach, Julie M, Drach, John C, Townsend, Leroy B
Published in Journal of medicinal chemistry (15.06.2000)
Published in Journal of medicinal chemistry (15.06.2000)
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Journal Article
Studies on Anti-HSV Activity and Cytotoxicity of Morinda citrifolia L. Noni Leaf
Selvam, Periyasamy, Breitenbach, Julie M., Borysko, Katherine Z., Drach, John C.
Published in Antiviral research (01.05.2011)
Published in Antiviral research (01.05.2011)
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Journal Article
Synthesis and Activity of Vidarabine d-Amino Acid Prodrugs as Potential Pox Virus Agents
Breitenbach, Julie M., Shen, Wei, Hilfinger, John, Drach, John C.
Published in Antiviral research (01.05.2008)
Published in Antiviral research (01.05.2008)
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Journal Article
Resistance of Human Cytomegalovirus to Cyclopropavir Involves a Novel Mutation in UL97
Borysko, Katherine Z., Gentry, Brian G., Breitenbach, Julie M., Zemlicka, Jiri, Drach, John C.
Published in Antiviral research (01.05.2008)
Published in Antiviral research (01.05.2008)
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