A chemical–genetic interaction map of small molecules using high‐throughput imaging in cancer cells
Breinig, Marco, Klein, Felix A, Huber, Wolfgang, Boutros, Michael
Published in Molecular systems biology (01.12.2015)
Published in Molecular systems biology (01.12.2015)
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Journal Article
Mitoferrin2 is a synthetic lethal target for chromosome 8p deleted cancers
Krieg, Stephan, Rohde, Thomas, Rausch, Tobias, Butthof, Luise, Wendler-Link, Lena, Eckert, Christoph, Breuhahn, Kai, Galy, Bruno, Korbel, Jan, Billmann, Maximilian, Breinig, Marco, Tschaharganeh, Darjus F
Published in Genome medicine (17.06.2024)
Published in Genome medicine (17.06.2024)
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Journal Article
Splicing stimulates siRNA formation at Drosophila DNA double-strand breaks
Merk, Karin, Breinig, Marco, Böttcher, Romy, Krebs, Stefan, Blum, Helmut, Boutros, Michael, Förstemann, Klaus
Published in PLoS genetics (19.06.2017)
Published in PLoS genetics (19.06.2017)
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Journal Article
Detection of Marker-Free Precision Genome Editing and Genetic Variation through the Capture of Genomic Signatures
Billon, Pierre, Nambiar, Tarun S., Hayward, Samuel B., Zafra, Maria P., Schatoff, Emma M., Oshima, Koichi, Dunbar, Andrew, Breinig, Marco, Park, Young C., Ryu, Han S., Tschaharganeh, Darjus F., Levine, Ross L., Baer, Richard, Ferrando, Adolfo, Dow, Lukas E., Ciccia, Alberto
Published in Cell reports (Cambridge) (10.03.2020)
Published in Cell reports (Cambridge) (10.03.2020)
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Journal Article
Down‐regulation of tumor suppressor a kinase anchor protein 12 in human hepatocarcinogenesis by epigenetic mechanisms
Goeppert, Benjamin, Schmezer, Peter, Dutruel, Céline, Oakes, Christopher, Renner, Marcus, Breinig, Marco, Warth, Arne, Vogel, Monika Nadja, Mittelbronn, Michel, Mehrabi, Arianeb, Gdynia, Georg, Penzel, Roland, Longerich, Thomas, Breuhahn, Kai, Popanda, Odilia, Plass, Christoph, Schirmacher, Peter, Kern, Michael André
Published in Hepatology (Baltimore, Md.) (01.12.2010)
Published in Hepatology (Baltimore, Md.) (01.12.2010)
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Journal Article
A high‐throughput RNAi screen for detection of immune‐checkpoint molecules that mediate tumor resistance to cytotoxic T lymphocytes
Khandelwal, Nisit, Breinig, Marco, Speck, Tobias, Michels, Tillmann, Kreutzer, Christiane, Sorrentino, Antonio, Sharma, Ashwini Kumar, Umansky, Ludmila, Conrad, Heinke, Poschke, Isabel, Offringa, Rienk, König, Rainer, Bernhard, Helga, Machlenkin, Arthur, Boutros, Michael, Beckhove, Philipp
Published in EMBO molecular medicine (01.04.2015)
Published in EMBO molecular medicine (01.04.2015)
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Journal Article
Expression and therapeutic relevance of heat-shock protein 90 in pancreatic endocrine tumors
Mayer, Philipp, Harjung, Andreas, Breinig, Marco, Fischer, Lars, Ehemann, Volker, Malz, Mona, Scherübl, Hans, Britsch, Sarah, Werner, Jens, Kern, Michael A, Bläker, Hendrik, Schirmacher, Peter, Bergmann, Frank
Published in Endocrine-related cancer (01.06.2012)
Published in Endocrine-related cancer (01.06.2012)
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Journal Article
Establishment, characterization and drug sensitivity testing in primary cultures of human thymoma and thymic carcinoma
Ehemann, Volker, Kern, Michael A., Breinig, Marco, Schnabel, Philipp A., Gunawan, Bastian, Schulten, Hans‐Jörg, Schlaeger, Christoph, Radlwimmer, Bernhard, Steger, Christina M., Dienemann, Hendrik, Lichter, Peter, Schirmacher, Peter, Rieker, Ralf J.
Published in International journal of cancer (15.06.2008)
Published in International journal of cancer (15.06.2008)
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Journal Article
Cyclooxygenase-2 (COX-2) - A Therapeutic Target in Liver Cancer?
Breinig, Marco, Schirmacher, Peter, Kern, Michael André
Published in Current pharmaceutical design (01.11.2007)
Published in Current pharmaceutical design (01.11.2007)
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Journal Article
Expression and Mutational Status of PDGFR in Thymic Tumours
MEISTER, Michael, KAHL, Philip, RIEKER, Ralf J, MULEY, Thomas, MORRESI-HAUF, Alicia, SEBENING, Christian, KERN, Michael A, BREINIG, Marco, SCHNABEL, Philipp, DIENEMANN, Hendrik, SCHIRMACHER, Peter
Published in Anticancer research (01.10.2009)
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Published in Anticancer research (01.10.2009)
Journal Article
GenomeCRISPR - a database for high-throughput CRISPR/Cas9 screens
Rauscher, Benedikt, Heigwer, Florian, Breinig, Marco, Winter, Jan, Boutros, Michael
Published in Nucleic acids research (04.01.2017)
Published in Nucleic acids research (04.01.2017)
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Journal Article
Optimized base editors enable efficient editing in cells, organoids and mice
Zafra, Maria Paz, Schatoff, Emma M, Katti, Alyna, Foronda, Miguel, Breinig, Marco, Schweitzer, Anabel Y, Simon, Amber, Han, Teng, Goswami, Sukanya, Montgomery, Emma, Thibado, Jordana, Kastenhuber, Edward R, Sánchez-Rivera, Francisco J, Shi, Junwei, Vakoc, Christopher R, Lowe, Scott W, Tschaharganeh, Darjus F, Dow, Lukas E
Published in Nature biotechnology (01.10.2018)
Published in Nature biotechnology (01.10.2018)
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Journal Article
CRISPR library designer (CLD): software for multispecies design of single guide RNA libraries
Heigwer, Florian, Zhan, Tianzuo, Breinig, Marco, Winter, Jan, Brügemann, Dirk, Leible, Svenja, Boutros, Michael
Published in Genome Biology (24.03.2016)
Published in Genome Biology (24.03.2016)
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Journal Article
E-TALEN: a web tool to design TALENs for genome engineering
Heigwer, Florian, Kerr, Grainne, Walther, Nike, Glaeser, Kathrin, Pelz, Oliver, Breinig, Marco, Boutros, Michael
Published in Nucleic acids research (01.11.2013)
Published in Nucleic acids research (01.11.2013)
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Journal Article
Phosphatidylinositol 4-Kinase III Alpha Governs Cytoskeletal Organization for Invasiveness of Liver Cancer Cells
Tran, Cong Si, Kersten, Julia, Yan, Jingyi, Breinig, Marco, Huth, Thorben, Poth, Tanja, Colasanti, Ombretta, Riedl, Tobias, Faure-Dupuy, Suzanne, Diehl, Stefan, Verhoye, Lieven, Li, Teng-Feng, Lingemann, Marit, Schult, Philipp, Ahlén, Gustaf, Frelin, Lars, Kühnel, Florian, Vondran, Florian W.R., Breuhahn, Kai, Meuleman, Philip, Heikenwälder, Mathias, Schirmacher, Peter, Bartenschlager, Ralf, Laketa, Vibor, Roessler, Stephanie, Tschaharganeh, Darjus Felix, Sällberg, Matti, Lohmann, Volker
Published in Gastroenterology (New York, N.Y. 1943) (01.08.2024)
Published in Gastroenterology (New York, N.Y. 1943) (01.08.2024)
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Journal Article
Targeting heat shock protein 90 with non‐quinone inhibitors: A novel chemotherapeutic approach in human hepatocellular carcinoma
Breinig, Marco, Caldas‐Lopes, Eloisi, Goeppert, Benjamin, Malz, Mona, Rieker, Ralf, Bergmann, Frank, Schirmacher, Peter, Mayer, Matthias, Chiosis, Gabriela, Kern, Michael André
Published in Hepatology (Baltimore, Md.) (01.07.2009)
Published in Hepatology (Baltimore, Md.) (01.07.2009)
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Journal Article
Abstract 245: Identification of novel immune checkpoints as potential therapeutic targets in pancreatic ductal adenocarcinoma (PDAC) using RNAi screening
Sorrentino, Antonio, Michels, Tillmann, Menevse, Ayse Nur, Khandelwal, Nisit, Breinig, Marco, Poschke, Isabel, Offringa, Rienk, Boutros, Michael, Beckhove, Philipp
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article