CC-122, a pleiotropic pathway modifier, mimics an interferon response and has antitumor activity in DLBCL
Hagner, Patrick R., Man, Hon-Wah, Fontanillo, Celia, Wang, Maria, Couto, Suzana, Breider, Mike, Bjorklund, Chad, Havens, Courtney G., Lu, Gang, Rychak, Emily, Raymon, Heather, Narla, Rama Krishna, Barnes, Leo, Khambatta, Gody, Chiu, Hsiling, Kosek, Jolanta, Kang, Jian, Amantangelo, Michael D., Waldman, Michelle, Lopez-Girona, Antonia, Cai, Ti, Pourdehnad, Michael, Trotter, Matthew, Daniel, Thomas O., Schafer, Peter H., Klippel, Anke, Thakurta, Anjan, Chopra, Rajesh, Gandhi, Anita K.
Published in Blood (06.08.2015)
Published in Blood (06.08.2015)
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Clinical and pharmacodynamic analysis of pomalidomide dosing strategies in myeloma: impact of immune activation and cereblon targets
Sehgal, Kartik, Das, Rituparna, Zhang, Lin, Verma, Rakesh, Deng, Yanhong, Kocoglu, Mehmet, Vasquez, Juan, Koduru, Srinivas, Ren, Yan, Wang, Maria, Couto, Suzana, Breider, Mike, Hansel, Donna, Seropian, Stuart, Cooper, Dennis, Thakurta, Anjan, Yao, Xiaopan, Dhodapkar, Kavita M., Dhodapkar, Madhav V.
Published in Blood (25.06.2015)
Published in Blood (25.06.2015)
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Discovery of Highly Potent and Selective Pan-Aurora Kinase Inhibitors with Enhanced in Vivo Antitumor Therapeutic Index
Liu, Gang, Abraham, Sunny, Tran, Lan, Vickers, Troy D, Xu, Shimin, Hadd, Michael J, Quiambao, Sheena, Holladay, Mark W, Hua, Helen, Ford Pulido, Julia M, Gunawardane, Ruwanthi N, Davis, Mindy I, Eichelberger, Shawn R, Apuy, Julius L, Gitnick, Dana, Gardner, Michael F, James, Joyce, Breider, Mike A, Belli, Barbara, Armstrong, Robert C, Treiber, Daniel K
Published in Journal of medicinal chemistry (12.04.2012)
Published in Journal of medicinal chemistry (12.04.2012)
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Discovery of AC710, a Globally Selective Inhibitor of Platelet-Derived Growth Factor Receptor-Family Kinases
Liu, Gang, Campbell, Brian T, Holladay, Mark W, Ford Pulido, Julia M, Hua, Helen, Gitnick, Dana, Gardner, Michael F, James, Joyce, Breider, Mike A, Brigham, Daniel, Belli, Barbara, Armstrong, Robert C, Treiber, Daniel K
Published in ACS medicinal chemistry letters (13.12.2012)
Published in ACS medicinal chemistry letters (13.12.2012)
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Abstract 5445: Dual-color immunohistochemistry assays for measuring Aiolos and Ikaros proteins in multiple myeloma patient samples
Ren, Yan, Wang, Maria, Couto, Suzana, Hansel, Donna, Gandhi, Anita K., Hagner, Patrick, Thakurta, Anjan, Chopra, Rajesh, Breider, Mike
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Abstract 1354: Comparison of pomalidomide dosing strategies in lenalidomide-refractory myeloma: Impact on clinical outcome, immune activation and cereblon targets
Das, Rituparna, Sehgal, Kartik, Zhang, Lin, Verma, Rakesh, Deng, Yanhong, Kocoglu, Mehmet, Vasquez, Juan, Koduru, Srini, Ren, Yan, Wang, Maria, Couto, Suzana, Breider, Mike, Hansel, Donna, Seropian, Stuart, Cooper, Dennis, Thakurta, Anjan, Yao, Xiaopan, Dhodapkar, Kavita M., Dhodapkar, Madhav V.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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CC-122 Has Potent Anti-Lymphoma Activity through Destruction of the Aiolos and Ikaros Transcription Factors and Induction of Interferon Response Pathways
Hagner, Patrick, Wang, Maria, Couto, Suzana, Breider, Mike, Fontanillo, Celia, Trotter, Matthew, Bjorklund, Chad C, Havens, Courtney G., Raymon, Heather K, Narla, Rama Krishna, Barnes, Leo, Waldman, Michelle, Daniel, Tom, Klippel, Anke, Pourdehnad, Michael, Thakurta, Anjan, Chopra, Rajesh, Gandhi, Anita K.
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Degradation of Aiolos and Ikaros Followed By Downregulation of c-Myc and then IRF4 Leads to Programmed Cell Death in Myeloma Cells Sensitive to IMiDs® Immunomodulatory Compounds
Bjorklund, Chad C, Havens, Courtney G., Hagner, Patrick R, Gandhi, Anita K., Wang, Maria, Amatangelo, Michael D, Lu, Ling, Wang, Huisheng, Breider, Mike, Ren, Yan, Lopez-Girona, Antonia, Thakurta, Anjan, Klippel, Anke, Chopra, Rajesh
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Retinal degeneration in rats induced by CI-1010, a 2-nitroimidazole radiosensitizer
Breider, M A, Pilcher, G D, Graziano, M J, Gough, A W
Published in Toxicologic pathology (01.03.1998)
Published in Toxicologic pathology (01.03.1998)
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METHODS FOR DETERMINING DRUG EFFICACY FOR THE TREATMENT OF DIFFUSE LARGE B-CELL LYMPHOMA, MULTIPLE MYELOMA, AND MYELOID CANCERS
HAGNER PATRICK, GANDHI ANITA, HOLLENBACH PAUL, MACBETH KYLE, BREIDER MIKE, COUTO SUZANA STURLINI, TROTTER MATTHEW WILLIAM BURNELL, WANG MARIA YINGLIN, CHOPRA RAJESH, HAVENS COURTNEY G, KLIPPEL ANKE, REN YAN
Year of Publication 29.07.2016
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Year of Publication 29.07.2016
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Tumor cell-enhanced sensitivity of vascular endothelial cells to photodynamic therapy
Yang, Z, Lu, X, Frazier, D L, Panjehpour, M, Breider, M A
Published in Lasers in surgery and medicine (1994)
Published in Lasers in surgery and medicine (1994)
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METHODS FOR DETERMINING DRUG EFFICACY FOR THE TREATMENT OF DIFFUSE LARGE B-CELL LYMPHOMA, MULTIPLE MYELOMA, AND MYELOID CANCERS
GANDHI, ANITA, KLIPPEL, ANKE, HAGNER, PATRICK, BREIDER, MIKE, HOLLENBACH, PAUL, TROTTER, MATTHEW WILLIAM BURNELL, COUTO, SUZANA STURLINI, HAVENS, COURTNEY G, CHOPRA, RAJESH, MACBETH, KYLE, WANG, MARIA YINGLIN, REN, YAN
Year of Publication 19.09.2023
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Year of Publication 19.09.2023
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METHODS FOR DETERMINING DRUG EFFICACY FOR THE TREATMENT OF DIFFUSE LARGE B-CELL LYMPHOMA, MULTIPLE MYELOMA, AND MYELOID CANCERS
WANG, Maria Yinglin, CHOPRA, Rajesh, TROTTER, Matthew William Burnell, KLIPPEL, Anke, HOLLENBACH, Paul, COUTO, Suzana Sturlini, BREIDER, Mike, MACBETH, Kyle, HAVENS, Courtney G, REN, Yan, HAGNER, Patrick, GANDHI, Anita
Year of Publication 06.01.2022
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Year of Publication 06.01.2022
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METHODS FOR DETERMINING DRUG EFFICACY FOR THE TREATMENT OF DIFFUSE LARGE B-CELL LYMPHOMA, MULTIPLE MYELOMA, AND MYELOID CANCERS
WANG, Maria, Yinglin, TROTTER, Matthew William, Burnell, COUTO, Suzana, Sturlini, CHOPRA, Rajesh, KLIPPEL, Anke, HOLLENBACH, Paul, BREIDER, Mike, MACBETH, Kyle, HAVENS, Courtney, G, REN, Yan, HAGNER, Patrick, GANDHI, Anita
Year of Publication 10.11.2021
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Year of Publication 10.11.2021
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Methods for determining drug efficacy for the treatment of diffuse large B-cell lymphoma, multiple myeloma, and myeloid cancers
Trotter, Matthew William Burnell, Wang, Maria Yinglin, Klippel, Anke, Gandhi, Anita, Ren, Yan, Breider, Mike, Hollenbach, Paul, Havens, Courtney G, Macbeth, Kyle, Chopra, Rajesh, Hagner, Patrick, Couto, Suzana Sturlini
Year of Publication 04.05.2021
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Year of Publication 04.05.2021
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Methods for determining drug efficacy for the treatment of diffuse large B-cell lymphoma, multiple myeloma, and myeloid cancers
Trotter, Matthew William Burnell, Wang, Maria Yinglin, Klippel, Anke, Gandhi, Anita, Ren, Yan, Breider, Mike, Hollenbach, Paul, Havens, Courtney G, Macbeth, Kyle, Chopra, Rajesh, Hagner, Patrick, Couto, Suzana Sturlini
Year of Publication 01.04.2021
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Year of Publication 01.04.2021
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METHODS FOR DETERMINING DRUG EFFICACY FOR THE TREATMENT OF DIFFUSE LARGE B-CELL LYMPHOMA, MULTIPLE MYELOMA, AND MYELOID CANCERS
WANG, Maria Yinglin, CHOPRA, Rajesh, TROTTER, Matthew William Burnell, KLIPPEL, Anke, HOLLENBACH, Paul, COUTO, Suzana Sturlini, BREIDER, Mike, MACBETH, Kyle, HAVENS, Courtney G, REN, Yan, HAGNER, Patrick, GANDHI, Anita
Year of Publication 03.01.2019
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Year of Publication 03.01.2019
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Métodos para determinar la eficacia del fármaco para el tratamiento de linfoma difuso de células B grandes, mieloma múltiple y cánceres mieloides
COUTO, Suzana, HAVENS, Courtney, CHOPRA, Rajesh, TROTTER, Matthew William, KLIPPEL, Anke, HOLLENBACH, Paul, BREIDER, Mike, MACBETH, Kyle, REN, Yan, HAGNER, Patrick, GANDHI, Anita, WANG, Maria
Year of Publication 31.03.2022
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Year of Publication 31.03.2022
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