Molecular characterization of mutant TP53 acute myeloid leukemia and high-risk myelodysplastic syndrome
Grob, Tim, Al Hinai, Adil S.A., Sanders, Mathijs A., Kavelaars, François G., Rijken, Melissa, Gradowska, Patrycja L., Biemond, Bart J., Breems, Dimitri A., Maertens, Johan, van Marwijk Kooy, Marinus, Pabst, Thomas, de Weerdt, Okke, Ossenkoppele, Gert J., van de Loosdrecht, Arjan A., Huls, Gerwin A., Cornelissen, Jan J., Beverloo, H. Berna, Löwenberg, Bob, Jongen-Lavrencic, Mojca, Valk, Peter J.M.
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Monosomal Karyotype in Acute Myeloid Leukemia: A Better Indicator of Poor Prognosis Than a Complex Karyotype
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Measurable residual disease-guided therapy in intermediate-risk acute myeloid leukemia patients is a valuable strategy in reducing allogeneic transplantation without negatively affecting survival
Tettero, Jesse M, Ngai, Lok Lam, Bachas, Costa, Breems, Dimitri A, Fischer, Thomas, Gjertsen, Bjorn T, Gradowska, Patrycja, Griskevicius, Laimonas, Janssen, Jeroen J W M, Juliusson, Gunnar, Maertens, Johan, Manz, Markus G, Pabst, Thomas, Passweg, Jakob, Porkka, Kimmo, Valk, Peter J M, Löwenberg, Bob, Ossenkoppele, Gert J, Cloos, Jacqueline
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Prognostic Index for Adult Patients With Acute Myeloid Leukemia in First Relapse
BREEMS, Dimitri A, VAN PUTTEN, Wim L. J, BOOGAERTS, Marc A, LÖWENBERG, Bob, HUIJGENS, Peter C, OSSENKOPPELE, Gert J, VERHOEF, Gregor E. G, VERDONCK, Leo F, VELLENGA, Edo, DE GREEF, Georgine E, JACKY, Emanuel, VAN DER LELIE, Johannes
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The added value of multi‐state modelling in a randomized controlled trial: The HOVON 102 study re‐analyzed
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Published in Cancer medicine (Malden, MA) (01.02.2022)
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Moxetumomab pasudotox in relapsed/refractory hairy cell leukemia
Kreitman, Robert J., Dearden, Claire, Zinzani, Pier Luigi, Delgado, Julio, Karlin, Lionel, Robak, Tadeusz, Gladstone, Douglas E., le Coutre, Philipp, Dietrich, Sascha, Gotic, Mirjana, Larratt, Loree, Offner, Fritz, Schiller, Gary, Swords, Ronan, Bacon, Larry, Bocchia, Monica, Bouabdallah, Krimo, Breems, Dimitri A., Cortelezzi, Agostino, Dinner, Shira, Doubek, Michael, Gjertsen, Bjorn Tore, Gobbi, Marco, Hellmann, Andrzej, Lepretre, Stephane, Maloisel, Frederic, Ravandi, Farhad, Rousselot, Philippe, Rummel, Mathias, Siddiqi, Tanya, Tadmor, Tamar, Troussard, Xavier, Yi, Cecilia Arana, Saglio, Giuseppe, Roboz, Gail J., Balic, Kemal, Standifer, Nathan, He, Peng, Marshall, Shannon, Wilson, Wyndham, Pastan, Ira, Yao, Nai-Shun, Giles, Francis
Published in Leukemia (01.08.2018)
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CD34+CD38− leukemic stem cell frequency to predict outcome in acute myeloid leukemia
Zeijlemaker, Wendelien, Grob, Tim, Meijer, Rosa, Hanekamp, Diana, Kelder, Angèle, Carbaat-Ham, Jannemieke C., Oussoren-Brockhoff, Yvonne J. M., Snel, Alexander N., Veldhuizen, Dennis, Scholten, Willemijn J., Maertens, Johan, Breems, Dimitri A., Pabst, Thomas, Manz, Markus G., van der Velden, Vincent H. J., Slomp, Jennichjen, Preijers, Frank, Cloos, Jacqueline, van de Loosdrecht, Arjan A., Löwenberg, Bob, Valk, Peter J. M., Jongen-Lavrencic, Mojca, Ossenkoppele, Gert J., Schuurhuis, Gerrit J.
Published in Leukemia (01.05.2019)
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Therapeutic value of clofarabine in younger and middle-aged (18-65 years) adults with newly diagnosed AML
Löwenberg, Bob, Pabst, Thomas, Maertens, Johan, van Norden, Yvette, Biemond, Bart J., Schouten, Harry C., Spertini, Olivier, Vellenga, Edo, Graux, Carlos, Havelange, Violaine, de Greef, Georgine E., de Weerdt, Okke, Legdeur, Marie-Cecile J.C., Kuball, Juergen, Kooy, Marinus van Marwijk, Gjertsen, Bjorn T., Jongen-Lavrencic, Mojca, van de Loosdrecht, Arjan A., van Lammeren-Venema, Daniëlle, Hodossy, Beata, Breems, Dimitri A., Chalandon, Yves, Passweg, Jakob, Valk, Peter J.M., Manz, Markus G., Ossenkoppele, Gert J.
Published in Blood (23.03.2017)
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Prospective validation of the prognostic relevance of CD34+CD38– AML stem cell frequency in the HOVON-SAKK132 trial
Ngai, Lok Lam, Hanekamp, Diana, Janssen, Fleur, Carbaat-Ham, Jannemieke, Hofland, Maaike A. M. A., Fayed, Mona M. H. E, Kelder, Angèle, Oudshoorn-van Marsbergen, Laura, Scholten, Willemijn J., Snel, Alexander N., Bachas, Costa, Tettero, Jesse M., Breems, Dimitri A., Fischer, Thomas, Gjertsen, Bjørn T., Griškevičius, Laimonas, Juliusson, Gunnar, van de Loosdrecht, Arjan A., Maertens, Johan A., Manz, Markus G., Pabst, Thomas, Passweg, Jakob R., Porkka, Kimmo, Valk, Peter J. M., Gradowska, Patrycja, Löwenberg, Bob, de Leeuw, David C., Janssen, Jeroen J. W. M., Ossenkoppele, Gert J., Cloos, Jacqueline
Published in Blood (25.05.2023)
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Concordance in measurable residual disease result after first and second induction cycle in acute myeloid leukemia: An outcome- and cost-analysis
Tettero, Jesse M., Al-Badri, Waleed K. W., Ngai, Lok Lam, Bachas, Costa, Breems, Dimitri A., van Elssen, Catharina H. M. J., Fischer, Thomas, Gjertsen, Bjorn T., van Gorkom, Gwendolyn N. Y., Gradowska, Patrycja, Greuter, Marjolein J. E., Griskevicius, Laimonas, Juliusson, Gunnar, Maertens, Johan, Manz, Markus G., Pabst, Thomas, Passweg, Jakob, Porkka, Kimmo, Löwenberg, Bob, Ossenkoppele, Gert J., Janssen, Jeroen J. W. M., Cloos, Jacqueline
Published in Frontiers in oncology (10.10.2022)
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A phase 2, randomized, double‐blind, multicenter study comparing siltuximab plus best supportive care (BSC) with placebo plus BSC in anemic patients with International Prognostic Scoring System low‐ or intermediate‐1–risk myelodysplastic syndrome
Garcia‐Manero, Guillermo, Gartenberg, Gary, Steensma, David P., Schipperus, Martin R., Breems, Dimitri A., Paz, Raquel, Valcárcel, David, Kranenburg, Britte, Reddy, Manjula, Komrokji, Rami S.
Published in American journal of hematology (01.09.2014)
Published in American journal of hematology (01.09.2014)
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Various distinctive cytogenetic abnormalities in patients with acute myeloid leukaemia aged 60 years and older express adverse prognostic value: results from a prospective clinical trial
Van Der Holt, Bronno, Breems, Dimitri A., Berna Beverloo, H., Van Den Berg, Eva, Burnett, Alan K., Sonneveld, Pieter, Löwenberg, Bob
Published in British journal of haematology (01.01.2007)
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Autologous bone marrow transplantation as consolidation therapy in the treatment of adult patients under 60 years with acute myeloid leukaemia in first complete remission: a prospective randomized Dutch–Belgian Haemato‐Oncology Co‐operative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK) trial
Breems, Dimitri A., Boogaerts, Marc A., Dekker, Adriaan W., Van Putten, Wim L. J., Sonneveld, Pieter, Huijgens, Peter C., Van der Lelie, Johannes, Vellenga, Edo, Gratwohl, Alois, Verhoef, Gregor E. G., Verdonck, Leo F., Löwenberg, Bob
Published in British journal of haematology (01.01.2005)
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Successful treatment of systemic amyloidosis with hepatic involvement and factor X deficiency by high dose melphalan chemotherapy and autologous stem cell reinfusion
Breems, Dimitri A., Sonneveld, Pieter, de Man, Rob A., Leebeek, Frank W. G.
Published in European journal of haematology (01.03.2004)
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Bayesian Inference for Optimization of Interim Analysis in Clinical Trials By Incorporation of Historical Data: Reanalysis of the HOVON AML 132 Clinical Trial
Van Der Maas, Niek, Nasserinejad, Kazem, Pabst, Thomas, Maertens, Johan A., Breems, Dimitri A., Manz, Markus G, Cloos, Jacqueline, Ossenkoppele, Gert J., Floisand, Yngvar, Gradowska, Patrycja, Lowenberg, Bob, Huls, Gerwin A., Postmus, Douwe, Pignatti, Francesco, Cornelissen, Jan J., Versluis, Jurjen
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Outcome of Intensively Treated Elderly AML Patients Reported to the Harmony Alliance Compares Well to Outcome of Control Patients of the Prospective Randomized HOVON 103 Study in Elderly AML
Hermans, Sjoerd J.F., Versluis, Jurjen, van Norden, Yvette, van Werkhoven, Erik D., Janssen, Jeroen J.W.M., Huls, Gerwin A., Lowenberg, Bob, Pabst, Thomas, Breems, Dimitri A., Berkx, Elizabeth, Dinmohamed, Avinash G., Huijgens, Peter C., Sträng, Eric, Hernández-Rivas, Jesús María, Döhner, Hartmut, Sobas, Marta, Bullinger, Lars, Ayala, Rosa, Martinez-Lopez, Joaquin, Metzeler, Klaus H, Haferlach, Torsten, Thiede, Christian, Uyl-De Groot, Carin A., Ossenkoppele, Gert J., Pignatti, Francesco, Cornelissen, Jan J.
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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