Advances in therapeutic applications of extracellular vesicles
Wiklander, Oscar P B, Brennan, Meadhbh Á, Lötvall, Jan, Breakefield, Xandra O, El Andaloussi, Samir
Published in Science translational medicine (15.05.2019)
Published in Science translational medicine (15.05.2019)
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Coding and noncoding landscape of extracellular RNA released by human glioma stem cells
Wei, Zhiyun, Batagov, Arsen O., Schinelli, Sergio, Wang, Jintu, Wang, Yang, El Fatimy, Rachid, Rabinovsky, Rosalia, Balaj, Leonora, Chen, Clark C., Hochberg, Fred, Carter, Bob, Breakefield, Xandra O., Krichevsky, Anna M.
Published in Nature communications (26.10.2017)
Published in Nature communications (26.10.2017)
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Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma
Shao, Huilin, Chung, Jaehoon, Lee, Kyungheon, Balaj, Leonora, Min, Changwook, Carter, Bob S., Hochberg, Fred H., Breakefield, Xandra O., Lee, Hakho, Weissleder, Ralph
Published in Nature communications (11.05.2015)
Published in Nature communications (11.05.2015)
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Viral vectors for therapy of neurologic diseases
Choudhury, Sourav R., Hudry, Eloise, Maguire, Casey A., Sena-Esteves, Miguel, Breakefield, Xandra O., Grandi, Paola
Published in Neuropharmacology (01.07.2017)
Published in Neuropharmacology (01.07.2017)
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Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy
Shao, Huilin, Chung, Jaehoon, Balaj, Leonora, Charest, Alain, Bigner, Darell D, Carter, Bob S, Hochberg, Fred H, Breakefield, Xandra O, Weissleder, Ralph, Lee, Hakho
Published in Nature medicine (01.12.2012)
Published in Nature medicine (01.12.2012)
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High levels of AAV vector integration into CRISPR-induced DNA breaks
Hanlon, Killian S., Kleinstiver, Benjamin P., Garcia, Sara P., Zaborowski, Mikołaj P., Volak, Adrienn, Spirig, Stefan E., Muller, Alissa, Sousa, Alexander A., Tsai, Shengdar Q., Bengtsson, Niclas E., Lööv, Camilla, Ingelsson, Martin, Chamberlain, Jeffrey S., Corey, David P., Aryee, Martin J., Joung, J. Keith, Breakefield, Xandra O., Maguire, Casey A., György, Bence
Published in Nature communications (30.09.2019)
Published in Nature communications (30.09.2019)
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Small RNA Sequencing across Diverse Biofluids Identifies Optimal Methods for exRNA Isolation
Srinivasan, Srimeenakshi, Yeri, Ashish, Cheah, Pike See, Chung, Allen, Danielson, Kirsty, De Hoff, Peter, Filant, Justyna, Laurent, Clara D., Laurent, Lucie D., Magee, Rogan, Moeller, Courtney, Murthy, Venkatesh L., Nejad, Parham, Paul, Anu, Rigoutsos, Isidore, Rodosthenous, Rodosthenis, Shah, Ravi V., Simonson, Bridget, To, Cuong, Wong, David, Yan, Irene K., Zhang, Xuan, Balaj, Leonora, Breakefield, Xandra O., Daaboul, George, Gandhi, Roopali, Lapidus, Jodi, Londin, Eric, Patel, Tushar, Raffai, Robert L., Sood, Anil K., Alexander, Roger P., Das, Saumya, Laurent, Louise C.
Published in Cell (04.04.2019)
Published in Cell (04.04.2019)
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MiR-21 in the extracellular vesicles (EVs) of cerebrospinal fluid (CSF): a platform for glioblastoma biomarker development
Akers, Johnny C, Ramakrishnan, Valya, Kim, Ryan, Skog, Johan, Nakano, Ichiro, Pingle, Sandeep, Kalinina, Juliya, Hua, Wei, Kesari, Santosh, Mao, Ying, Breakefield, Xandra O, Hochberg, Fred H, Van Meir, Erwin G, Carter, Bob S, Chen, Clark C
Published in PloS one (21.10.2013)
Published in PloS one (21.10.2013)
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SCS macrophages suppress melanoma by restricting tumor-derived vesicle–B cell interactions
Pucci, Ferdinando, Garris, Christopher, Lai, Charles P., Newton, Andita, Pfirschke, Christina, Engblom, Camilla, Alvarez, David, Sprachman, Melissa, Evavold, Charles, Magnuson, Angela, von Andrian, Ulrich H., Glatz, Katharina, Breakefield, Xandra O., Mempel, Thorsten R., Weissleder, Ralph, Pittet, Mikael J.
Published in Science (American Association for the Advancement of Science) (08.04.2016)
Published in Science (American Association for the Advancement of Science) (08.04.2016)
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Glioblastoma-Associated Microglia Reprogramming Is Mediated by Functional Transfer of Extracellular miR-21
Abels, Erik R., Maas, Sybren L.N., Nieland, Lisa, Wei, Zhiyun, Cheah, Pike See, Tai, Eric, Kolsteeg, Christy-Joy, Dusoswa, Sophie A., Ting, David T., Hickman, Suzanne, El Khoury, Joseph, Krichevsky, Anna M., Broekman, Marike L.D., Breakefield, Xandra O.
Published in Cell reports (Cambridge) (17.09.2019)
Published in Cell reports (Cambridge) (17.09.2019)
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Genetically Engineered Microvesicles Carrying Suicide mRNA/Protein Inhibit Schwannoma Tumor Growth
Mizrak, Arda, Bolukbasi, Mehmet Fatih, Ozdener, Gokhan Baris, Brenner, Gary J, Madlener, Sibylle, Erkan, Erdogan Pekcan, Ströbel, Thomas, Breakefield, Xandra O, Saydam, Okay
Published in Molecular therapy (01.01.2013)
Published in Molecular therapy (01.01.2013)
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Rescue of Hearing by Gene Delivery to Inner-Ear Hair Cells Using Exosome-Associated AAV
György, Bence, Sage, Cyrille, Indzhykulian, Artur A., Scheffer, Deborah I., Brisson, Alain R., Tan, Sisareuth, Wu, Xudong, Volak, Adrienn, Mu, Dakai, Tamvakologos, Panos I., Li, Yaqiao, Fitzpatrick, Zachary, Ericsson, Maria, Breakefield, Xandra O., Corey, David P., Maguire, Casey A.
Published in Molecular therapy (01.02.2017)
Published in Molecular therapy (01.02.2017)
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Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles
Reátegui, Eduardo, van der Vos, Kristan E., Lai, Charles P., Zeinali, Mahnaz, Atai, Nadia A., Aldikacti, Berent, Floyd, Frederick P., H. Khankhel, Aimal, Thapar, Vishal, Hochberg, Fred H., Sequist, Lecia V., Nahed, Brian V., S. Carter, Bob, Toner, Mehmet, Balaj, Leonora, T. Ting, David, Breakefield, Xandra O., Stott, Shannon L.
Published in Nature communications (12.01.2018)
Published in Nature communications (12.01.2018)
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Heparin affinity purification of extracellular vesicles
Balaj, Leonora, Atai, Nadia A., Chen, Weilin, Mu, Dakai, Tannous, Bakhos A., Breakefield, Xandra O., Skog, Johan, Maguire, Casey A.
Published in Scientific reports (19.05.2015)
Published in Scientific reports (19.05.2015)
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Glioma-Derived miRNA-Containing Extracellular Vesicles Induce Angiogenesis by Reprogramming Brain Endothelial Cells
Lucero, Rocco, Zappulli, Valentina, Sammarco, Alessandro, Murillo, Oscar D., Cheah, Pike See, Srinivasan, Srimeenakshi, Tai, Eric, Ting, David T., Wei, Zhiyun, Roth, Matthew E., Laurent, Louise C., Krichevsky, Anna M., Breakefield, Xandra O., Milosavljevic, Aleksandar
Published in Cell reports (Cambridge) (18.02.2020)
Published in Cell reports (Cambridge) (18.02.2020)
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Emerging roles of extracellular vesicles in the nervous system
Rajendran, Lawrence, Bali, Jitin, Barr, Maureen M, Court, Felipe A, Krämer-Albers, Eva-Maria, Picou, Frederic, Raposo, Graça, van der Vos, Kristan E, van Niel, Guillaume, Wang, Juan, Breakefield, Xandra O
Published in The Journal of neuroscience (12.11.2014)
Published in The Journal of neuroscience (12.11.2014)
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Directly visualized glioblastoma-derived extracellular vesicles transfer RNA to microglia/macrophages in the brain
van der Vos, Kristan E, Abels, Erik R, Zhang, Xuan, Lai, Charles, Carrizosa, Esteban, Oakley, Derek, Prabhakar, Shilpa, Mardini, Osama, Crommentuijn, Matheus H W, Skog, Johan, Krichevsky, Anna M, Stemmer-Rachamimov, Anat, Mempel, Thorsten R, El Khoury, Joseph, Hickman, Suzanne E, Breakefield, Xandra O
Published in Neuro-oncology (Charlottesville, Va.) (01.01.2016)
Published in Neuro-oncology (Charlottesville, Va.) (01.01.2016)
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