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Carboplatin in BRCA1/2-mutated and triple-negative breast cancer BRCAness subgroups: the TNT Trial
Tutt, Andrew, Tovey, Holly, Cheang, Maggie Chon U, Kernaghan, Sarah, Kilburn, Lucy, Gazinska, Patrycja, Owen, Julie, Abraham, Jacinta, Barrett, Sophie, Barrett-Lee, Peter, Brown, Robert, Chan, Stephen, Dowsett, Mitchell, Flanagan, James M, Fox, Lisa, Grigoriadis, Anita, Gutin, Alexander, Harper-Wynne, Catherine, Hatton, Matthew Q, Hoadley, Katherine A, Parikh, Jyoti, Parker, Peter, Perou, Charles M, Roylance, Rebecca, Shah, Vandna, Shaw, Adam, Smith, Ian E, Timms, Kirsten M, Wardley, Andrew M, Wilson, Gregory, Gillett, Cheryl, Lanchbury, Jerry S, Ashworth, Alan, Rahman, Nazneen, Harries, Mark, Ellis, Paul, Pinder, Sarah E, Bliss, Judith M
Published in Nature medicine (01.05.2018)
Published in Nature medicine (01.05.2018)
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Emerging evidence on the role of breast microbiota on the development of breast cancer in high-risk patients
Actis, Silvia, Cazzaniga, Massimiliano, Bounous, Valentina Elisabetta, D’Alonzo, Marta, Rosso, Roberta, Accomasso, Francesca, Minella, Carola, Biglia, Nicoletta
Published in Carcinogenesis (New York) (15.12.2023)
Published in Carcinogenesis (New York) (15.12.2023)
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Breast Cancer Risk After Salpingo-Oophorectomy in Healthy BRCA1/2 Mutation Carriers: Revisiting the Evidence for Risk Reduction
Heemskerk-Gerritsen, B. A. M., Seynaeve, C., van Asperen, C. J., Ausems, M. G. E. M., Collée, J. M., van Doorn, H. C., Gomez Garcia, E. B., Kets, C. M., van Leeuwen, F. E., Meijers-Heijboer, H. E. J., Mourits, M. J. E., van Os, T. A. M., Vasen, H. F. A., Verhoef, S., Rookus, M. A., Hooning, M. J.
Published in JNCI : Journal of the National Cancer Institute (01.05.2015)
Published in JNCI : Journal of the National Cancer Institute (01.05.2015)
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The contribution of deleterious germline mutations in BRCA1, BRCA2 and the mismatch repair genes to ovarian cancer in the population
Song, H., Cicek, M. S., Dicks, E., Harrington, P., Ramus, S. J., Cunningham, J. M., Fridley, B. L., Tyrer, J. P., Alsop, J., Jimenez-Linan, M., Gayther, S. A., Goode, E. L., Pharoah, P. D. P.
Published in Human molecular genetics (01.09.2014)
Published in Human molecular genetics (01.09.2014)
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The spectrum of BRCA mutations and characteristics of BRCA‐associated breast cancers in China: Screening of 2,991 patients and 1,043 controls by next‐generation sequencing
Lang, Guan‐Tian, Shi, Jin‐Xiu, Hu, Xin, Zhang, Chen‐Hui, Shan, Ling, Song, Chuan‐Gui, Zhuang, Zhi‐Gang, Cao, A‐Yong, Ling, Hong, Yu, Ke‐Da, Li, Shan, Sun, Meng‐Hong, Zhou, Xiao‐Yan, Huang, Wei, Shao, Zhi‐Ming
Published in International journal of cancer (01.07.2017)
Published in International journal of cancer (01.07.2017)
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Detection of inherited mutations for breast and ovarian cancer using genomic capture and massively parallel sequencing
Walsh, Tom, Lee, Ming K., Casadei, Silvia, Thornton, Anne M., Stray, Sunday M., Pennil, Christopher, Nord, Alex S., Mandell, Jessica B., Swisher, Elizabeth M., King, Mary-Claire
Published in Proceedings of the National Academy of Sciences - PNAS (13.07.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (13.07.2010)
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Frequency of premature menopause in women who carry a BRCA1 or BRCA2 mutation
Finch, Amy, Valentini, Adriana, Greenblatt, Ellen, Lynch, Henry T., Ghadirian, Parviz, Armel, Susan, Neuhausen, Susan L., Kim-Sing, Charmaine, Tung, Nadine, Karlan, Beth, Foulkes, William D., Sun, Ping, Narod, Steven
Published in Fertility and sterility (01.05.2013)
Published in Fertility and sterility (01.05.2013)
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Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance
Johnson, Neil, Johnson, Shawn F., Yao, Wei, Li, Yu-Chen, Choi, Young-Eun, Bernhardy, Andrea J., Wang, Yifan, Capelletti, Marzia, Sarosiek, Kristopher A., Moreau, Lisa A., Chowdhury, Dipanjan, Wickramanayake, Anneka, Harrell, Maria I., Liu, Joyce F., D'Andrea, Alan D., Miron, Alexander, Swisher, Elizabeth M., Shapiro, Geoffrey I.
Published in Proceedings of the National Academy of Sciences - PNAS (15.10.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (15.10.2013)
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The First Nationwide Multicenter Prevalence Study of Germline BRCA1 and BRCA2 Mutations in Chinese Ovarian Cancer Patients
Wu, Xiaohua, Wu, Lingying, Kong, Beihua, Liu, Jihong, Yin, Rutie, Wen, Hao, Li, Ning, Bu, Hualei, Feng, Yanling, Li, Qingli, Lu, Xuesong, Wei, Jia, Zhu, Xuehua, Mills, John, Ellison, Gillian, Gutjahr, Thorsten, Liu, Yuzhen
Published in International journal of gynecological cancer (01.10.2017)
Published in International journal of gynecological cancer (01.10.2017)
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Second-line olaparib maintenance therapy is associated with poor response to subsequent chemotherapy in BRCA1/2-mutated epithelial ovarian cancer: A multicentre retrospective study
Park, Junsik, Kim, Se Ik, Jeong, Soo Young, Kim, Yup, Bookman, Michael A., Kim, Jae-Weon, Kim, Byoung-Gie, Lee, Jung-Yun
Published in Gynecologic oncology (01.04.2022)
Published in Gynecologic oncology (01.04.2022)
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Mutational Status is Associated with a Higher Rate of Pathologic Complete Response After Neoadjuvant Chemotherapy in Hormone Receptor-Positive Breast Cancer
Myers, Sara P., Sevilimedu, Varadan, Barrio, Andrea V., Tadros, Audree B., Mamtani, Anita, Robson, Mark E., Morrow, Monica, Lee, Minna K.
Published in Annals of surgical oncology (01.12.2023)
Published in Annals of surgical oncology (01.12.2023)
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Hereditary breast and ovarian cancer: from genes to molecular targeted therapies
Ponti, Giovanni, De Angelis, Carmine, Ponti, Rosamaria, Pongetti, Linda, Losi, Lorena, Sticchi, Alberto, Tomasi, Aldo, Ozben, Tomris
Published in Critical reviews in clinical laboratory sciences (01.12.2023)
Published in Critical reviews in clinical laboratory sciences (01.12.2023)
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Inherited predisposition to breast cancer among African American women
Churpek, Jane E., Walsh, Tom, Zheng, Yonglan, Moton, Zakiya, Thornton, Anne M., Lee, Ming K., Casadei, Silvia, Watts, Amanda, Neistadt, Barbara, Churpek, Matthew M., Huo, Dezheng, Zvosec, Cecilia, Liu, Fang, Niu, Qun, Marquez, Rafael, Zhang, Jing, Fackenthal, James, King, Mary-Claire, Olopade, Olufunmilayo I.
Published in Breast cancer research and treatment (01.01.2015)
Published in Breast cancer research and treatment (01.01.2015)
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Ethnicity-specific BRCA1, BRCA2, PALB2, and ATM pathogenic alleles in breast and ovarian cancer patients from the North Caucasus
Sokolenko, Anna P., Bakaeva, Elvina Kh, Venina, Aigul R., Kuligina, Ekaterina Sh, Romanko, Alexandr A., Aleksakhina, Svetlana N., Belysheva, Yana V., Belogubova, Evgeniya V., Stepanov, Ilya A., Zaitseva, Olga A., Yatsuk, Olga S., Togo, Alexandr V., Khamgokov, Zaur M., Kadyrova, Azinat O., Pirmagomedov, Albert Sh, Bolieva, Marina B., Epkhiev, Alexandr A., Tsutsaev, Aslan K., Chakhieva, Madina D., Khabrieva, Khalimat M., Khabriev, Idris M., Murachuev, Mirza A., Buttaeva, Bella N., Baboshkina, Liliya S., Bayramkulova, Fatima I., Katchiev, Islam R., Alieva, Lina Kh, Raskin, Grigory A., Orlov, Sergey V., Khachmamuk, Zarema K., Levonyan, Karine R., Gichko, Dariya M., Kirtbaya, Dmitriy V., Degtyariov, Alexey M., Sultanova, Luisa V., Musayeva, Hedi S., Belyaev, Alexey M., Imyanitov, Evgeny N.
Published in Breast cancer research and treatment (01.01.2024)
Published in Breast cancer research and treatment (01.01.2024)
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Prostate cancer risk, screening and management in patients with germline BRCA1/2 mutations
Rajwa, Pawel, Quhal, Fahad, Pradere, Benjamin, Gandaglia, Giorgio, Ploussard, Guillaume, Leapman, Michael S., Gore, John L., Paradysz, Andrzej, Tilki, Derya, Merseburger, Axel S., Morgan, Todd M., Briganti, Alberto, Palapattu, Ganesh S., Shariat, Shahrokh F.
Published in Nature reviews. Urology (01.04.2023)
Published in Nature reviews. Urology (01.04.2023)
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Germline BRCA2 K3326X and CHEK2 I157T mutations increase risk for sporadic pancreatic ductal adenocarcinoma
Obazee, O., Archibugi, L., Andriulli, A., Soucek, P., Małecka‐Panas, E., Ivanauskas, A., Johnson, T., Gazouli, M., Pausch, T., Lawlor, R. T., Cavestro, G. M., Milanetto, A. C., Di Leo, M., Pasquali, C., Hegyi, P., Szentesi, A., Radu, C. E., Gheorghe, C., Theodoropoulos, G. E., Bergmann, F., Brenner, H., Vodickova, L., Katzke, V., Campa, D., Strobel, O., Kaiser, J., Pezzilli, R., Federici, F., Mohelnikova‐Duchonova, B., Boggi, U., Lemstrova, R., Johansen, J. S., Bojesen, S. E., Chen, I., Jensen, B. V., Capurso, G., Pazienza, V., Dervenis, C., Sperti, C., Mambrini, A., Hackert, T., Kaaks, R., Basso, D., Talar‐Wojnarowska, R., Maiello, E., Izbicki, J. R., Cuk, K., Saum, K. U., Cantore, M., Kupcinskas, J., Palmieri, O., Delle Fave, G., Landi, S., Salvia, R., Fogar, P., Vashist, Y. K., Scarpa, A., Vodicka, P., Tjaden, C., Iskierka‐Jazdzewska, E., Canzian, F.
Published in International journal of cancer (01.08.2019)
Published in International journal of cancer (01.08.2019)
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Differential methylation of circulating free DNA assessed through cfMeDiP as a new tool for breast cancer diagnosis and detection of BRCA1/2 mutation
Grisolia, Piera, Tufano, Rossella, Iannarone, Clara, De Falco, Antonio, Carlino, Francesca, Graziano, Cinzia, Addeo, Raffaele, Scrima, Marianna, Caraglia, Francesco, Ceccarelli, Anna, Nuzzo, Pier Vitale, Cossu, Alessia Maria, Forte, Stefano, Giuffrida, Raffaella, Orditura, Michele, Caraglia, Michele, Ceccarelli, Michele
Published in Journal of translational medicine (15.10.2024)
Published in Journal of translational medicine (15.10.2024)
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Biallelic BRCA2 Mutations Shape the Somatic Mutational Landscape of Aggressive Prostate Tumors
Decker, Brennan, Karyadi, Danielle M., Davis, Brian W., Karlins, Eric, Tillmans, Lori S., Stanford, Janet L., Thibodeau, Stephen N., Ostrander, Elaine A.
Published in American journal of human genetics (05.05.2016)
Published in American journal of human genetics (05.05.2016)
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Improving performance of multigene panels for genomic analysis of cancer predisposition
Shirts, Brian H., Casadei, Silvia, Jacobson, Angela L., Lee, Ming K., Gulsuner, Suleyman, Bennett, Robin L., Miller, Margaret, Hall, Sarah A., Hampel, Heather, Hisama, Fuki M., Naylor, Lorraine V., Goetsch, Cathleen, Leppig, Kathleen, Tait, Jonathan F., Scroggins, Sheena M., Turner, Emily H., Livingston, Robert, Salipante, Stephen J., King, Mary-Claire, Walsh, Tom, Pritchard, Colin C.
Published in Genetics in medicine (01.10.2016)
Published in Genetics in medicine (01.10.2016)
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