1-(Indolin-1-yl)-1-phenyl-3-propan-2-olamines as Potent and Selective Norepinephrine Reuptake Inhibitors
Vu, An T, Cohn, Stephen T, Zhang, Puwen, Kim, Callain Y, Mahaney, Paige E, Bray, Jenifer A, Johnston, Grace H, Koury, Elizabeth J, Cosmi, Scott A, Deecher, Darlene C, Smith, Valerie A, Harrison, James E, Leventhal, Liza, Whiteside, Garth T, Kennedy, Jeffrey D, Trybulski, Eugene J
Published in Journal of medicinal chemistry (11.03.2010)
Published in Journal of medicinal chemistry (11.03.2010)
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Discovery of Novel Selective Norepinephrine Inhibitors: 1-(2-Morpholin-2-ylethyl)-3-aryl-1,3-dihydro-2,1,3-benzothiadiazole 2,2-Dioxides (WYE-114152)
O’Neill, David J, Adedoyin, Adedayo, Bray, Jenifer A, Deecher, Darlene C, Fensome, Andrew, Goldberg, Joel A, Harrison, Jim, Leventhal, Liza, Mann, Charles, Mark, Lilly, Nogle, Lisa, Sullivan, Nicole R, Spangler, Taylor B, Terefenko, Eugene A, Trybulski, Eugene J, Uveges, Albert J, Vu, An, Whiteside, Garth T, Zhang, Puwen
Published in Journal of medicinal chemistry (13.10.2011)
Published in Journal of medicinal chemistry (13.10.2011)
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Discovery of Novel Selective Norepinephrine Reuptake Inhibitors: 4-[3-Aryl-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ols (WYE-103231)
O’Neill, David J, Adedoyin, Adedayo, Alfinito, Peter D, Bray, Jenifer A, Cosmi, Scott, Deecher, Darlene C, Fensome, Andrew, Harrison, Jim, Leventhal, Liza, Mann, Charles, McComas, Casey C, Sullivan, Nicole R, Spangler, Taylor B, Uveges, Albert J, Trybulski, Eugene J, Whiteside, Garth T, Zhang, Puwen
Published in Journal of medicinal chemistry (10.06.2010)
Published in Journal of medicinal chemistry (10.06.2010)
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Dual acting norepinephrine reuptake inhibitors and 5-HT2A receptor antagonists: Identification, synthesis and activity of novel 4-aminoethyl-3-(phenylsulfonyl)-1H-indoles
HEFFERNAN, GavinD, COGHLAN, Richard D, COSMI, Scott A, JOHNSTON, Grace H, KENNEY, Thomas, KOURY, Elizabeth, WINNEKER, Richard C, DEECHER, Darlene C, TRYBULSKI, Eugene J, MANAS, Eric S, MCDEVITT, Robert E, YANFANG LI, MAHANEY, Paige E, ROBICHAUD, Albert J, HUSELTON, Christine, ALFINITO, Peter, BRAY, Jenifer A
Published in Bioorganic & medicinal chemistry (15.11.2009)
Published in Bioorganic & medicinal chemistry (15.11.2009)
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Quantitative analysis of gene regulation by seven clinically relevant progestins suggests a highly similar mechanism of action through progesterone receptors in T47D breast cancer cells
Bray, Jeffrey D., Jelinsky, Scott, Ghatge, Radhika, Bray, Jenifer A., Tunkey, Christopher, Saraf, Kathryn, Jacobsen, Britta M., Richer, Jennifer K., Brown, Eugene L., Winneker, Richard C., Horwitz, Kathryn B., Lyttle, C. Richard
Published in The Journal of steroid biochemistry and molecular biology (01.12.2005)
Published in The Journal of steroid biochemistry and molecular biology (01.12.2005)
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Structure−Activity Relationships of the Cycloalkanol Ethylamine Scaffold: Discovery of Selective Norepinephrine Reuptake Inhibitors
Mahaney, Paige E, Gavrin, Lori K, Trybulski, Eugene J, Stack, Gary P, Vu, An T, Cohn, Stephen T, Ye, Fei, Belardi, Justin K, Santilli, Arthur A, Sabatucci, Joseph P, Leiter, Jennifer, Johnston, Grace H, Bray, Jenifer A, Burroughs, Kevin D, Cosmi, Scott A, Leventhal, Liza, Koury, Elizabeth J, Zhang, Yingru, Mugford, Cheryl A, Ho, Douglas M, Rosenzweig-Lipson, Sharon J, Platt, Brian, Smith, Valerie A, Deecher, Darlene C
Published in Journal of medicinal chemistry (10.07.2008)
Published in Journal of medicinal chemistry (10.07.2008)
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Intratracheal injection of adenovirus containing the human MNSOD transgene protects athymic nude mice from irradiation-induced organizing alveolitis
Epperly, Michael W, Bray, Jenifer A, Krager, Stephen, Berry, Luann M, Gooding, William, Engelhardt, John F, Zwacka, Ralf, Travis, Elizabeth L, Greenberger, Joel S
Published in International journal of radiation oncology, biology, physics (1999)
Published in International journal of radiation oncology, biology, physics (1999)
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Structure–activity relationships of the 1-amino-3-(1 H-indol-1-yl)-3-phenylpropan-2-ol series of monoamine reuptake inhibitors
Mahaney, Paige E., Kim, Callain Y., Coghlan, Richard D., Cohn, Stephen T., Heffernan, Gavin D., Huselton, Christine A., Terefenko, Eugene A., Vu, An T., Zhang, Puwen, Burroughs, Kevin D., Cosmi, Scott A., Bray, Jenifer A., Johnston, Grace H., Deecher, Darlene C., Trybulski, Eugene J.
Published in Bioorganic & medicinal chemistry letters (01.10.2009)
Published in Bioorganic & medicinal chemistry letters (01.10.2009)
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Discovery of WAY-260022, a Potent and Selective Inhibitor of the Norepinephrine Transporter
Gavrin, Lori K, Mahaney, Paige E, Jenkins, Douglas, Nogle, Lisa M, Mugford, Cheryl A, Huselton, Christine, Leiter, Jennifer, Johnston, Grace H, Bray, Jenifer A, Burroughs, Kevin D, Cosmi, Scott A, Alfinito, Peter, Ho, Douglas M, Deecher, Darlene C, Trybulski, Eugene J
Published in ACS medicinal chemistry letters (10.06.2010)
Published in ACS medicinal chemistry letters (10.06.2010)
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3-(Arylamino)-3-phenylpropan-2-olamines as a new series of dual norepinephrine and serotonin reuptake inhibitors
Vu, An T., Cohn, Stephen T., Terefenko, Eugene A., Moore, William J., Zhang, Puwen, Mahaney, Paige E., Trybulski, Eugene J., Goljer, Igor, Dooley, Rebecca, Bray, Jenifer A., Johnston, Grace H., Leiter, Jennifer, Deecher, Darlene C.
Published in Bioorganic & medicinal chemistry letters (01.05.2009)
Published in Bioorganic & medicinal chemistry letters (01.05.2009)
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Dual acting norepinephrine reuptake inhibitors and 5-HT 2A receptor antagonists: Identification, synthesis and activity of novel 4-aminoethyl-3-(phenylsulfonyl)-1 H-indoles
Heffernan, Gavin D., Coghlan, Richard D., Manas, Eric S., McDevitt, Robert E., Li, Yanfang, Mahaney, Paige E., Robichaud, Albert J., Huselton, Christine, Alfinito, Peter, Bray, Jenifer A., Cosmi, Scott A., Johnston, Grace H., Kenney, Thomas, Koury, Elizabeth, Winneker, Richard C., Deecher, Darlene C., Trybulski, Eugene J.
Published in Bioorganic & medicinal chemistry (2009)
Published in Bioorganic & medicinal chemistry (2009)
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Dual acting norepinephrine reuptake inhibitors and 5-HT(2A) receptor antagonists: Identification, synthesis and activity of novel 4-aminoethyl-3-(phenylsulfonyl)-1H-indoles
Heffernan, Gavin D, Coghlan, Richard D, Manas, Eric S, McDevitt, Robert E, Li, Yanfang, Mahaney, Paige E, Robichaud, Albert J, Huselton, Christine, Alfinito, Peter, Bray, Jenifer A, Cosmi, Scott A, Johnston, Grace H, Kenney, Thomas, Koury, Elizabeth, Winneker, Richard C, Deecher, Darlene C, Trybulski, Eugene J
Published in Bioorganic & medicinal chemistry (15.11.2009)
Published in Bioorganic & medicinal chemistry (15.11.2009)
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Biology of marrow stromal cell lines derived from long-term bone marrow cultures of Trp53-deficient mice
Epperly, M W, Bray, J A, Carlos, T M, Prochownik, E, Greenberger, J S
Published in Radiation research (01.07.1999)
Published in Radiation research (01.07.1999)
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Overexpression of the human MNSOD transgene in vitro protects 32D CL 3 murine hematopoietic progenitor cells from irradiation-induced apoptosis
Epperly Michael, W, Bray Jenifer, A, Escobar, Patricia, Bigbee, William L, Watkins, Simon C, Greenberger, Joel S
Published in International journal of radiation oncology, biology, physics (1998)
Published in International journal of radiation oncology, biology, physics (1998)
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Overexpression of the human manganese superoxide dismutase (MnSOD) transgene in subclones of murine hematopoietic progenitor cell line 32D cl 3 decreases irradiation-induced apoptosis but does not alter G2/M or G1/S phase cell cycle arrest
Epperly, M W, Bray, J A, Esocobar, P, Bigbee, W L, Watkins, S, Greenberger, J S
Published in Radiation oncology investigations (1999)
Published in Radiation oncology investigations (1999)
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