Regional Differences in the Absolute Abundance of Transporters, Receptors and Tight Junction Molecules at the Blood-Arachnoid Barrier and Blood-Spinal Cord Barrier among Cervical, Thoracic and Lumbar Spines in Dogs
Takeuchi, Hina, Suzuki, Masayoshi, Goto, Ryohei, Tezuka, Kenta, Fuchs, Holger, Ishiguro, Naoki, Terasaki, Tetsuya, Braun, Clemens, Uchida, Yasuo
Published in Pharmaceutical research (01.07.2022)
Published in Pharmaceutical research (01.07.2022)
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Journal Article
Quantification of Transporter and Receptor Proteins in Dog Brain Capillaries and Choroid Plexus: Relevance for the Distribution in Brain and CSF of Selected BCRP and P‑gp Substrates
Braun, Clemens, Sakamoto, Atsushi, Fuchs, Holger, Ishiguro, Naoki, Suzuki, Shinobu, Cui, Yunhai, Klinder, Klaus, Watanabe, Michitoshi, Terasaki, Tetsuya, Sauer, Achim
Published in Molecular pharmaceutics (02.10.2017)
Published in Molecular pharmaceutics (02.10.2017)
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Journal Article
Towards a Quantitative Mechanistic Understanding of Localized Pulmonary Tissue Retention-A Combined In Vivo/In Silico Approach Based on Four Model Drugs
Himstedt, Anneke, Braun, Clemens, Wicha, Sebastian Georg, Borghardt, Jens Markus
Published in Pharmaceutics (29.04.2020)
Published in Pharmaceutics (29.04.2020)
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Journal Article
Dichotomal Role of TNF in Experimental Pulmonary Edema Reabsorption
Braun, Clemens, Hamacher, Jurg, Morel, Denis R, Wendel, Albrecht, Lucas, Rudolf
Published in The Journal of immunology (1950) (01.09.2005)
Published in The Journal of immunology (1950) (01.09.2005)
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Journal Article
Understanding the suitability of established antibiotics for oral inhalation from a pharmacokinetic perspective: an integrated model-based investigation based on rifampicin, ciprofloxacin and tigecycline in vivo data
Himstedt, Anneke, Braun, Clemens, Wicha, Sebastian Georg, Borghardt, Jens Markus
Published in Journal of antimicrobial chemotherapy (28.10.2022)
Published in Journal of antimicrobial chemotherapy (28.10.2022)
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Journal Article
A human blood–arachnoid barrier atlas of transporters, receptors, enzymes, and tight junction and marker proteins: Comparison with dog and pig in absolute abundance
Uchida, Yasuo, Takeuchi, Hina, Goto, Ryohei, Braun, Clemens, Fuchs, Holger, Ishiguro, Naoki, Takao, Masaki, Tano, Mitsutoshi, Terasaki, Tetsuya
Published in Journal of neurochemistry (01.04.2022)
Published in Journal of neurochemistry (01.04.2022)
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Journal Article
Force and torque acting on particles in a transitionally rough open-channel flow
Chan-Braun, Clemens, García-Villalba, Manuel, Uhlmann, Markus
Published in Journal of fluid mechanics (10.10.2011)
Published in Journal of fluid mechanics (10.10.2011)
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Journal Article
Hypocretin-1 receptor antagonism improves inhibitory control during the Go/No-Go task in highly motivated, impulsive male mice
Metha, Jeremy, Ji, Yijun, Braun, Clemens, Nicholson, Janet R, De Lecea, Luis, Murawski, Carsten, Hoyer, Daniel, Jacobson, Laura H
Published in Psychopharmacology (Berlin, Germany) (18.06.2024)
Published in Psychopharmacology (Berlin, Germany) (18.06.2024)
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Journal Article
Discovery and development of BI 1265162, an ENaC inhibitor for the treatment of cystic fibrosis
Betzemeier, Bodo, Braun, Clemens, Sieger, Peter, Heckel, Armin, Linz, Günter, Linehan, Brian, Veser, Thomas, Wiedenmayer, Dieter, Kley, Jörg T.
Published in European journal of medicinal chemistry (05.02.2024)
Published in European journal of medicinal chemistry (05.02.2024)
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Journal Article
Impaired regenerative capacity and senescence‐associated secretory phenotype in mesenchymal stromal cells from samples of patients with aseptic joint arthroplasty loosening
Ebert, Regina, Weissenberger, Manuel, Braun, Clemens, Wagenbrenner, Mike, Herrmann, Marietta, Müller‐Deubert, Sigrid, Krug, Melanie, Jakob, Franz, Rudert, Maximilian
Published in Journal of orthopaedic research (01.02.2022)
Published in Journal of orthopaedic research (01.02.2022)
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Journal Article
Inkjet printing platform for fabrication of uniform, excipient-free drug particles for pulmonary delivery in a preclinical setting
Zakharyuta, Anastasia, Sieger, Peter, Braun, Clemens, Grube, Achim
Published in Journal of drug delivery science and technology (01.12.2019)
Published in Journal of drug delivery science and technology (01.12.2019)
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Journal Article
Discovery of tetrahydroindazoles as a novel class of potent and in vivo efficacious gamma secretase modulators
Gerlach, Kai, Hobson, Scott, Eickmeier, Christian, Groß, Ulrike, Braun, Clemens, Sieger, Peter, Garneau, Michel, Hoerer, Stefan, Heine, Niklas
Published in Bioorganic & medicinal chemistry (23.07.2018)
Published in Bioorganic & medicinal chemistry (23.07.2018)
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Journal Article
The potent and selective RIPK2 inhibitor BI 706039 improves intestinal inflammation in the TRUC mouse model of inflammatory bowel disease
Ermann, Joerg, Matmusaev, Mederbek, Haley, Emma K, Braun, Clemens, Jost, Felix, Mayer-Wrangowski, Svenja, Hsiao, Peng, Ting, Naitee, Li, Li, Terenzio, Donna, Chime, Jane, Lukas, Susan, Patnaude, Lori, Panzenbeck, Mark, Csordas, David, Zheng, Jie, Mierz, Diane, Simpson, Tom, King, F James, Klimowicz, Alex P, Mbow, M Lamine, Fine, Jay S, Miller, Craig A, Fogal, Steve E, Byrne, Fergus R
Published in American journal of physiology: Gastrointestinal and liver physiology (01.11.2021)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.11.2021)
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Journal Article
Fr482 BI 706039 IS A POTENT AND SELECTIVE INHIBITOR OF RIPK2 AND IMPROVES INTESTINAL INFLAMMATION IN THE TRUC MOUSE MODEL OF INFLAMMATORY BOWEL DISEASE
Ermann, Joerg, Matmusaev, Mederbek, Haley, Emma, Braun, Clemens, Jost, Felix, Mayer-Wrangowski, Svenja, Ting, Naitee, Li, Frank, Terenzio, Donna, Chime, Jane, Lukas, Susan, Panzenbeck, Mark, Csordas, David, Zheng, Jie, Mierz, Diane, King, Frank J., Klimowicz, Alexander C., Fine, Jay S., Miller, Craig, Fogal, Steve, Byrne, Fergus
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2021)
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Journal Article
코팅을 생성하도록 지정된 건조 프로세스를 조정하기 위한 방법 및 시스템
EBERLE FELIX, SCHMITT MARCEL, CETINEL FATIH, SCHAEFER STEPHAN, WOLF UWE, SCHMIDT HANSBERG BENJAMIN, CHAN BRAUN CLEMENS THOMAS
Year of Publication 02.06.2023
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Year of Publication 02.06.2023
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