The Tumor Necrosis Factor Receptor Stalk Regions Define Responsiveness to Soluble versus Membrane-Bound Ligand
Richter, Christine, Messerschmidt, Sylvia, Holeiter, Gerlinde, Tepperink, Jessica, Osswald, Sylvia, Zappe, Andrea, Branschädel, Marcus, Boschert, Verena, Mann, Derek A., Scheurich, Peter, Krippner-Heidenreich, Anja
Published in Molecular and Cellular Biology (01.07.2012)
Published in Molecular and Cellular Biology (01.07.2012)
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Journal Article
The transmembrane domains of TNF-related apoptosis-inducing ligand (TRAIL) receptors 1 and 2 co-regulate apoptotic signaling capacity
Neumann, Simon, Bidon, Tobias, Branschädel, Marcus, Krippner-Heidenreich, Anja, Scheurich, Peter, Doszczak, Malgorzata
Published in PloS one (03.08.2012)
Published in PloS one (03.08.2012)
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Journal Article
APG350 induces superior clustering of TRAIL receptors and shows therapeutic antitumor efficacy independent of cross-linking via Fcγ receptors
Gieffers, Christian, Kluge, Michael, Merz, Christian, Sykora, Jaromir, Thiemann, Meinolf, Schaal, René, Fischer, Carmen, Branschädel, Marcus, Abhari, Behnaz Ahangarian, Hohenberger, Peter, Fulda, Simone, Fricke, Harald, Hill, Oliver
Published in Molecular cancer therapeutics (01.12.2013)
Published in Molecular cancer therapeutics (01.12.2013)
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Journal Article
Single chain TNF derivatives with individually mutated receptor binding sites reveal differential stoichiometry of ligand receptor complex formation for TNFR1 and TNFR2
Boschert, Verena, Krippner-Heidenreich, Anja, Branschädel, Marcus, Tepperink, Jessica, Aird, Andrew, Scheurich, Peter
Published in Cellular signalling (01.07.2010)
Published in Cellular signalling (01.07.2010)
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Journal Article
Dual function of cysteine rich domain (CRD) 1 of TNF receptor type 1: Conformational stabilization of CRD2 and control of receptor responsiveness
Branschädel, Marcus, Aird, Andrew, Zappe, Andrea, Tietz, Carsten, Krippner-Heidenreich, Anja, Scheurich, Peter
Published in Cellular signalling (01.03.2010)
Published in Cellular signalling (01.03.2010)
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Journal Article
The Transmembrane Domains of TNF-Related Apoptosis-Inducing Ligand
Neumann, Simon, Bidon, Tobias, Branschädel, Marcus, Krippner-Heidenreich, Anja, Scheurich, Peter, Doszczak, Malgorzata
Published in PloS one (03.08.2012)
Published in PloS one (03.08.2012)
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Journal Article
Abstract 3856: Dimerized single chain TRAIL-receptor agonists do not depend on Fc-gamma-receptor cross-linking for anti-tumor efficacy in vivo
Gieffers, Christian, Kluge, Michael, Thiemann, Meinolf, Merz, Christian, Sykora, Jaromir, Fischer, Carmen, Branschädel, Marcus, Harald, Fricke, Hill, Oliver
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
Abstract LB-232: APG350, a dimerized single chain TRAIL receptor agonist with enhanced functional properties
Gieffers, Christian, Kluge, Michael, Hill, Oliver, Meinolf, Thiemann, Merz, Christian, Branschädel, Marcus, Harald, Fricke
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Journal Article
A humanized tumor necrosis factor receptor 1 (TNFR1)-specific antagonistic antibody for selective inhibition of tumor necrosis factor (TNF) action
Kontermann, Roland E, Münkel, Sabine, Neumeyer, Jens, Müller, Dafne, Branschädel, Marcus, Scheurich, Peter, Pfizenmaier, Klaus
Published in Journal of immunotherapy (1997) (01.04.2008)
Published in Journal of immunotherapy (1997) (01.04.2008)
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Journal Article
Membrane Environment Reduces the Accessible Conformational Space Available to an Integral Membrane Protein
Gerken, Uwe, Jelezko, Fedor, Götze, Britta, Branschädel, Marcus, Tietz, Carsten, Ghosh, Robin, Wrachtrup, Jörg
Published in The journal of physical chemistry. B (09.01.2003)
Published in The journal of physical chemistry. B (09.01.2003)
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Journal Article
TNF SUPERFAMILY COLLECTIN FUSION PROTEINS
BRANSCHÄDEL, Marcus, GIEFFERS, Christian, THIEMANN, Meinolf, HILL, Oliver
Year of Publication 18.09.2019
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Year of Publication 18.09.2019
Patent
GITRL-collectin fusion proteins and encoding nucleic acids
Thiemann, Meinolf, Gieffers, Christian, Branschädel, Marcus, Hill, Oliver
Year of Publication 19.06.2018
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Year of Publication 19.06.2018
Patent
TNF SUPERFAMILY COLLECTIN FUSION PROTEINS
BRANSCHÄDEL, Marcus, GIEFFERS, Christian, THIEMANN, Meinolf, HILL, Oliver
Year of Publication 16.05.2018
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Year of Publication 16.05.2018
Patent
TNF SUPERFAMILY COLLECTIN FUSION PROTEINS
BRANSCHÄDEL, Marcus, GIEFFERS, Christian, THIEMANN, Meinolf, HILL, Oliver
Year of Publication 25.10.2017
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Year of Publication 25.10.2017
Patent
GITRL COLLECTIN FUSION PROTEINS
HILL Oliver, THIEMANN Meinolf, BRANSCHÄDEL Marcus, GIEFFERS Christian
Year of Publication 23.03.2017
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Year of Publication 23.03.2017
Patent
CD40L collectin fusion proteins and encoding nucleic acid molecules
Hill Oliver, Thiemann Meinolf, Branschädel Marcus, Gieffers Christian
Year of Publication 27.12.2016
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Year of Publication 27.12.2016
Patent
Fusion proteins forming trimers
HILL, OLIVER, GIEFFERS, CHRISTIAN, THIEMANN, MEINOLF, BRANSCHÄDEL, MARCUS
Year of Publication 16.11.2016
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Year of Publication 16.11.2016
Patent
TNF SUPERFAMILY COLLECTIN FUSION PROTEINS
BRANSCHÄDEL, Marcus, GIEFFERS, Christian, THIEMANN, Meinolf, HILL, Oliver
Year of Publication 28.09.2016
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Year of Publication 28.09.2016
Patent
CD40L COLLECTIN FUSION PROTEINS
BRANSCHÄDEL MARCUS, THIEMANN MEINOLF, HILL OLIVER, GIEFFERS CHRISTIAN
Year of Publication 23.06.2016
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Year of Publication 23.06.2016
Patent
TNF superfamily collectin fusion proteins
HILL, OLIVER, GIFFERS, CHRISTIAN, THIEMANN, MEINOLF, BRANSCHÄDEL, MARCUS
Year of Publication 13.01.2016
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Year of Publication 13.01.2016
Patent