Ibrutinib–Rituximab or Chemoimmunotherapy for Chronic Lymphocytic Leukemia
Shanafelt, Tait D, Wang, Xin V, Kay, Neil E, Hanson, Curtis A, O’Brien, Susan, Barrientos, Jacqueline, Jelinek, Diane F, Braggio, Esteban, Leis, Jose F, Zhang, Cong C, Coutre, Steven E, Barr, Paul M, Cashen, Amanda F, Mato, Anthony R, Singh, Avina K, Mullane, Michael P, Little, Richard F, Erba, Harry, Stone, Richard M, Litzow, Mark, Tallman, Martin
Published in The New England journal of medicine (01.08.2019)
Published in The New England journal of medicine (01.08.2019)
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Journal Article
Long-term outcomes for ibrutinib-rituximab and chemoimmunotherapy in CLL: updated results of the E1912 trial
Shanafelt, Tait D, Wang, Xin Victoria, Hanson, Curtis A, Paietta, Elisabeth M, O'Brien, Susan, Barrientos, Jacqueline, Jelinek, Diane F, Braggio, Esteban, Leis, Jose F, Zhang, Cong Christine, Coutre, Steven E, Barr, Paul M, Cashen, Amanda F, Mato, Anthony R, Singh, Avina K, Mullane, Michael P, Little, Richard F, Erba, Harry, Stone, Richard M, Litzow, Mark, Tallman, Martin, Kay, Neil E
Published in Blood (14.07.2022)
Published in Blood (14.07.2022)
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Loss of FAM46C Promotes Cell Survival in Myeloma
Zhu, Yuan Xiao, Shi, Chang-Xin, Bruins, Laura A, Jedlowski, Patrick, Wang, Xuewei, Kortüm, K Martin, Luo, Moulun, Ahmann, Jonathan M, Braggio, Esteban, Stewart, A Keith
Published in Cancer research (Chicago, Ill.) (15.08.2017)
Published in Cancer research (Chicago, Ill.) (15.08.2017)
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Journal Article
Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide
Zhu, Yuan Xiao, Braggio, Esteban, Shi, Chang-Xin, Bruins, Laura A., Schmidt, Jessica E., Van Wier, Scott, Chang, Xiu-Bao, Bjorklund, Chad C., Fonseca, Rafael, Bergsagel, P. Leif, Orlowski, Robert Z., Stewart, A. Keith
Published in Blood (03.11.2011)
Published in Blood (03.11.2011)
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Targeted sequencing of refractory myeloma reveals a high incidence of mutations in CRBN and Ras pathway genes
Kortüm, K.Martin, Mai, Elias K., Hanafiah, Nur H., Shi, Chang-Xi, Zhu, Yuan-Xiao, Bruins, Laura, Barrio, Santiago, Jedlowski, Patrick, Merz, Maximilian, Xu, Jing, Stewart, Robert A., Andrulis, Mindaugas, Jauch, Anna, Hillengass, Jens, Goldschmidt, Hartmut, Bergsagel, P.Leif, Braggio, Esteban, Stewart, A.Keith, Raab, Marc S.
Published in Blood (01.09.2016)
Published in Blood (01.09.2016)
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Genome-Wide Analysis Uncovers Novel Recurrent Alterations in Primary Central Nervous System Lymphomas
Braggio, Esteban, Van Wier, Scott, Ojha, Juhi, McPhail, Ellen, Asmann, Yan W, Egan, Jan, da Silva, Jackline Ayres, Schiff, David, Lopes, M Beatriz, Decker, Paul A, Valdez, Riccardo, Tibes, Raoul, Eckloff, Bruce, Witzig, Thomas E, Stewart, A Keith, Fonseca, Rafael, O'Neill, Brian Patrick
Published in Clinical cancer research (01.09.2015)
Published in Clinical cancer research (01.09.2015)
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Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides
Egan, Jan B., Shi, Chang-Xin, Tembe, Waibhav, Christoforides, Alexis, Kurdoglu, Ahmet, Sinari, Shripad, Middha, Sumit, Asmann, Yan, Schmidt, Jessica, Braggio, Esteban, Keats, Jonathan J., Fonseca, Rafael, Bergsagel, P. Leif, Craig, David W., Carpten, John D., Stewart, A. Keith
Published in Blood (02.08.2012)
Published in Blood (02.08.2012)
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Journal Article
Precancer Atlas to Drive Precision Prevention Trials
Spira, Avrum, Yurgelun, Matthew B, Alexandrov, Ludmil, Rao, Anjana, Bejar, Rafael, Polyak, Kornelia, Giannakis, Marios, Shilatifard, Ali, Finn, Olivera J, Dhodapkar, Madhav, Kay, Neil E, Braggio, Esteban, Vilar, Eduardo, Mazzilli, Sarah A, Rebbeck, Timothy R, Garber, Judy E, Velculescu, Victor E, Disis, Mary L, Wallace, Douglas C, Lippman, Scott M
Published in Cancer research (Chicago, Ill.) (01.04.2017)
Published in Cancer research (Chicago, Ill.) (01.04.2017)
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Novel Richter Syndrome Xenograft Models to Study Genetic Architecture, Biology, and Therapy Responses
Vaisitti, Tiziana, Braggio, Esteban, Allan, John N, Arruga, Francesca, Serra, Sara, Zamò, Alberto, Tam, Wayne, Chadburn, Amy, Furman, Richard R, Deaglio, Silvia
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Identification of lenalidomide resistance pathways in myeloma and targeted resensitization using cereblon replacement, inhibition of STAT3 or targeting of IRF4
Zhu, Yuan Xiao, Shi, Chang-Xin, Bruins, Laura A., Wang, Xuewei, Riggs, Daniel L., Porter, Brooke, Ahmann, Jonathan M., de Campos, Cecilia Bonolo, Braggio, Esteban, Bergsagel, P. Leif, Stewart, A. Keith
Published in Blood cancer journal (New York) (11.02.2019)
Published in Blood cancer journal (New York) (11.02.2019)
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Journal Article
CRISPR Genome-Wide Screening Identifies Dependence on the Proteasome Subunit PSMC6 for Bortezomib Sensitivity in Multiple Myeloma
Shi, Chang-Xin, Kortüm, K Martin, Zhu, Yuan Xiao, Bruins, Laura A, Jedlowski, Patrick, Votruba, Patrick G, Luo, Moulun, Stewart, Robert A, Ahmann, Jonathan, Braggio, Esteban, Stewart, A Keith
Published in Molecular cancer therapeutics (01.12.2017)
Published in Molecular cancer therapeutics (01.12.2017)
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Journal Article
The genomic landscape of VkMYC myeloma highlights shared pathways of transformation between mice and humans
Maura, Francesco, Coffey, David G., Stein, Caleb K., Braggio, Esteban, Ziccheddu, Bachisio, Sharik, Meaghen E., Du, Megan T., Tafoya Alvarado, Yuliza, Shi, Chang-Xin, Zhu, Yuan Xiao, Meermeier, Erin W., Morgan, Gareth J., Landgren, Ola, Bergsagel, P. Leif, Chesi, Marta
Published in Nature communications (07.05.2024)
Published in Nature communications (07.05.2024)
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Journal Article
KRAS, NRAS, and BRAF mutations are highly enriched in trisomy 12 chronic lymphocytic leukemia and are associated with shorter treatment-free survival
Vendramini, Elena, Bomben, Riccardo, Pozzo, Federico, Benedetti, Dania, Bittolo, Tamara, Rossi, Francesca Maria, Dal Bo, Michele, Rabe, Kari G., Pozzato, Gabriele, Zaja, Francesco, Chiarenza, Annalisa, Di Raimondo, Francesco, Braggio, Esteban, Parikh, Sameer A., Kay, Neil E., Shanafelt, Tait D., Del Poeta, Giovanni, Gattei, Valter, Zucchetto, Antonella
Published in Leukemia (01.08.2019)
Published in Leukemia (01.08.2019)
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Polygenic risk score and risk of monoclonal B-cell lymphocytosis in caucasians and risk of chronic lymphocytic leukemia (CLL) in African Americans
Kleinstern, Geffen, Weinberg, J. Brice, Parikh, Sameer A., Braggio, Esteban, Achenbach, Sara J., Robinson, Dennis P., Norman, Aaron D., Rabe, Kari G., Boddicker, Nicholas J., Vachon, Celine M., Lesnick, Connie E., Call, Timothy G., Brander, Danielle M., Rassenti, Laura Z., Kipps, Thomas J., Olson, Janet E., Cerhan, James R., Kay, Neil E., Furman, Richard R., Hanson, Curtis A., Shanafelt, Tait D., Slager, Susan L.
Published in Leukemia (01.01.2022)
Published in Leukemia (01.01.2022)
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MicroRNA and long non-coding RNA analysis in IgM-monoclonal gammopathies reveals epigenetic influence on cellular functions and oncogenesis
Chohan, Karan, Paludo, Jonas, Dasari, Surendra, Mondello, Patrizia, Novak, Joseph P, Abeykoon, Jithma P, Wenzl, Kerstin, Yang, Zhi-Zhang, Jalali, Shahrzad, Krull, Jordan E, Braggio, Esteban, Manske, Michelle K, Paulus, Aneel, Reeder, Craig B, Ailawadhi, Sikander, Chanan-Khan, Asher, Kapoor, Prashant, Kyle, Robert A, Gertz, Morie A, Novak, Anne J, Ansell, Stephen M
Published in Haematologica (Roma) (01.05.2024)
Published in Haematologica (Roma) (01.05.2024)
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Identification of PIKfyve kinase as a target in multiple myeloma
de Campos, Cecilia Bonolo, Zhu, Yuan Xiao, Sepetov, Nikolai, Romanov, Sergei, Bruins, Laura Ann, Shi, Chang-Xin, Stein, Caleb K, Petit, Joachim L, Polito, Alysia N, Sharik, Meaghen E, Meermeier, Erin W, Ahmann, Gregory J, Armenta, Ilsel D Lopez, Kruse, Jonas, Bergsagel, P Leif, Chesi, Marta, Meurice, Nathalie, Braggio, Esteban, Stewart, A Keith
Published in Haematologica (Roma) (01.06.2020)
Published in Haematologica (Roma) (01.06.2020)
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Journal Article
Associations of history of vaccination and hospitalization due to infection with risk of monoclonal B-cell lymphocytosis
Boddicker, Nicholas J., Achenbach, Sara J., Parikh, Sameer A., Kleinstern, Geffen, Braggio, Esteban, Norman, Aaron D., Rabe, Kari G., Vachon, Celine M., Lesnick, Connie E., Call, Timothy G., Olson, Janet E., Cerhan, James R., Kay, Neil E., Hanson, Curtis A., Shanafelt, Tait D., Slager, Susan L.
Published in Leukemia (01.05.2022)
Published in Leukemia (01.05.2022)
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Journal Article
RNAi screen of the druggable genome identifies modulators of proteasome inhibitor sensitivity in myeloma including CDK5
Zhu, Yuan Xiao, Tiedemann, Rodger, Shi, Chang-Xin, Yin, Holly, Schmidt, Jessica E., Bruins, Laura A., Keats, Jonathan J., Braggio, Esteban, Sereduk, Chris, Mousses, Spyro, Stewart, A. Keith
Published in Blood (07.04.2011)
Published in Blood (07.04.2011)
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Journal Article
Hypodiploid multiple myeloma is characterized by more aggressive molecular markers than non-hyperdiploid multiple myeloma
Van Wier, Scott, Braggio, Esteban, Baker, Angela, Ahmann, Gregory, Levy, Joan, Carpten, John D, Fonseca, Rafael
Published in Haematologica (Roma) (01.10.2013)
Published in Haematologica (Roma) (01.10.2013)
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Evaluation of NUC-1031: a first-in-class ProTide in biliary tract cancer
Arora, Mansi, Bogenberger, James M., Abdelrahman, Amro, Leiting, Jennifer L., Chen, Xianfeng, Egan, Jan B., Kasimsetty, Aradhana, Lenkiewicz, Elzbieta, Malasi, Smriti, Uson, Pedro Luiz Serrano, Nagalo, Bolni Marius, Zhou, Yumei, Salomao, Marcela A., Kosiorek, Heidi E., Braggio, Esteban, Barrett, Michael T., Truty, Mark J., Borad, Mitesh J.
Published in Cancer chemotherapy and pharmacology (01.06.2020)
Published in Cancer chemotherapy and pharmacology (01.06.2020)
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