Cu-Catalyzed Hydroboration of Benzylidenecyclopropanes: Reaction Optimization, (Hetero)Aryl Scope, and Origins of Pathway Selectivity
Medina, Jose M, Kang, Taeho, Erbay, Tuğçe G, Shao, Huiling, Gallego, Gary M, Yang, Shouliang, Tran-Dubé, Michelle, Richardson, Paul F, Derosa, Joseph, Helsel, Ryan T, Patman, Ryan L, Wang, Fen, Ashcroft, Christopher P, Braganza, John F, McAlpine, Indrawan, Liu, Peng, Engle, Keary M
Published in ACS catalysis (06.12.2019)
Published in ACS catalysis (06.12.2019)
Get full text
Journal Article
Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain
Bagal, Sharan K, Andrews, Mark, Bechle, Bruce M, Bian, Jianwei, Bilsland, James, Blakemore, David C, Braganza, John F, Bungay, Peter J, Corbett, Matthew S, Cronin, Ciaran N, Cui, Jingrong Jean, Dias, Rebecca, Flanagan, Neil J, Greasley, Samantha E, Grimley, Rachel, James, Kim, Johnson, Eric, Kitching, Linda, Kraus, Michelle L, McAlpine, Indrawan, Nagata, Asako, Ninkovic, Sacha, Omoto, Kiyoyuki, Scales, Stephanie, Skerratt, Sarah E, Sun, Jianmin, Tran-Dubé, Michelle, Waldron, Gareth J, Wang, Fen, Warmus, Joseph S
Published in Journal of medicinal chemistry (09.08.2018)
Published in Journal of medicinal chemistry (09.08.2018)
Get full text
Journal Article
Continued exploration of the triazolopyridine scaffold as a platform for p38 MAP kinase inhibition
Jerome, Kevin D., Rucker, Paul V., Xing, Li, Shieh, Huey S., Baldus, John E., Selness, Shaun R., Letavic, Michael A., Braganza, John F., McClure, Kim F.
Published in Bioorganic & medicinal chemistry letters (15.01.2010)
Published in Bioorganic & medicinal chemistry letters (15.01.2010)
Get full text
Journal Article
Structure–activity relationships of triazolopyridine oxazole p38 inhibitors: Identification of candidates for clinical development
McClure, Kim F., Letavic, Michael A., Kalgutkar, Amit S., Gabel, Christopher A., Audoly, Laurent, Barberia, John T., Braganza, John F., Carter, Demetrius, Carty, Thomas J., Cortina, Santo R., Dombroski, Mark A., Donahue, Kathleen M., Elliott, Nancy C., Gibbons, Colleen P., Jordan, Crystal K., Kuperman, Alexander V., Labasi, Jeff M., LaLiberte, Ronald E., McCoy, Jennifer M., Naiman, Brian M., Nelson, Kendra L., Nguyen, Hang T., Peese, Kevin M., Sweeney, Francis J., Taylor, Timothy J., Trebino, Catherine E., Abramov, Yuriy A., Laird, Ellen R., Volberg, Walter A., Zhou, Jun, Bach, Justin, Lombardo, Franco
Published in Bioorganic & medicinal chemistry letters (15.08.2006)
Published in Bioorganic & medicinal chemistry letters (15.08.2006)
Get full text
Journal Article
Improved cyclization conditions to prepare 6-substituted pyrazolo[1,5-a]pyridines and pyrazolo[1,5-a]pyrazines using catalytic Ag(I) and Au(III) salts
Braganza, John F., Bernier, Louise, Botrous, Iriny, Collins, Michael R., Li, Baohua, McAlpine, Indrawan, Ninkovic, Sacha, Ren, Shijian, Sach, Neal, Tran-Dubé, Michelle, Zeng, Qingbin, Zheng, Baojiang
Published in Tetrahedron letters (14.10.2015)
Published in Tetrahedron letters (14.10.2015)
Get full text
Journal Article
The Synthesis of 3-pyrazinyl-pyrazolo [1,5-a] pyridines from an enol ether
Tran-Dubé, Michelle, Sach, Neal, Ninkovic, Sacha, Braganza, John F., Huang, Qinhua, Johnson, Benjamin, Collins, Michael Raymond
Published in Tetrahedron letters (15.08.2012)
Published in Tetrahedron letters (15.08.2012)
Get full text
Journal Article
compostos de indazol ou sal farmaceuticamente aceitável e composição farmacêutica
John F. Braganza, Michael David Johnson, Ye Hua, Allen J. Borchardt, Steven Lee Bender, Anna Maria Tempczyk-Russel, Cynthia Louise Palmer, Hiep The Luu, Michael David Varney, Siegfried Heinz Reich, Theodore Otto Johnson Jr, Michael Raymond Collins, Stephan James Cripps, Robert Steven Kania, Christine Thomas, Michael Brennan Wallace, Min Teng
Year of Publication 25.05.2021
Get full text
Year of Publication 25.05.2021
Patent
INDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PROTEIN KINASES, AND METHODS FOR THEIR USE
HUA, YE, LUU, HIEP THE, KANIA, ROBERT STEVEN, BENDER, STEVEN LEE, REICH, SIEGFRIED HEINZ, CRIPPS, STEPHAN JAMES, JR. JOHNSON, THEODORE OTTO, BRAGANZA, JOHN F, VARNEY, MICHAEL DAVID, PALMER, CYNTHIA LOUISE, THOMAS, CHRISTINE, TENG, MIN, WALLACE, MICHAEL BRENNAN, COLLINS, MICHAEL RAYMOND, JOHNSON, MICHAEL DAVID, TEMPCZYK-RUSSELL, ANNA MARIA, BORCHARDT, ALLEN J
Year of Publication 28.03.2013
Get full text
Year of Publication 28.03.2013
Patent
Indasoolihendid ja farmatseutilised kompositsioonid proteiini kinaaside inhibeerimiseks ning nende kasutamine
THEODORE OTTO JOHNSON JR, SIEGFRIED HEINZ REICH, MIN TENG, YE HUA, ALLEN J. BORCHARDT, CYNTHIA LOUISE PALMER, ROBERT STEVEN KANIA, MICHAEL DAVID JOHNSON, STEVEN LEE BENDER, MICHAEL BRENNAN WALLACE, STEPHAN JAMES CRIPPS, HIEP THE LUU, CHRISTINE THOMAS, ANNA MARIA TEMPCZYK-RUSSELL, MICHAEL DAVID VARNEY, MICHAEL RAYMOND COLLINS, JOHN F. BRAGANZA
Year of Publication 15.10.2012
Get full text
Year of Publication 15.10.2012
Patent
INDAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PROTEIN KINASES, AND METHODS FOR THEIR USE
JOHNSON MICHAEL DAVID, LUU HIEP THE, PALMER CYNTHIA LOUISE, BORCHARDT ALLEN J, BRAGANZA JOHN F, KANIA ROBERT STEVEN, VARNEY MICHAEL DAVID, BENDER STEVEN LEE, TENG MIN, HUA YE, THOMAS CHRISTINE, JOHNSON THEODORE OTTO JR, REICH SIEGFRIED HEINZ, CRIPPS STEPHAN JAMES, WALLACE MICHAEL BRENNAN, COLLINS MICHAEL RAYMOND, TEMPCZYK-RUSSELL ANNA MARIA
Year of Publication 31.08.2012
Get full text
Year of Publication 31.08.2012
Patent
Compounds and pharmaceutical compositions for inhibiting protein kinases
KANIA, ROBERT STEVEN, BENDER, STEVEN LEE, CRIPPS, STEPHAN JAMES, BORCHARDT, ALLEN J, BRAGANZA, JOHN F
Year of Publication 01.10.2006
Get full text
Year of Publication 01.10.2006
Patent
Indazol efnasambönd og lyfjafræðilegar blöndur til að hindra prótín kínasa og aðferð til að nota þau
THEODORE OTTO JOHNSON JR, SIEGFRIED HEINZ REICH, MIN TENG, YE HUA, ALLEN J. BORCHARDT, CYNTHIA LOUISE PALMER, ROBERT STEVEN KANIA, MICHAEL DAVID JOHNSON, STEVEN LEE BENDER, MICHAEL BRENNAN WALLACE, STEPHAN JAMES CRIPPS, HIEP THE LUU, CHRISTINE THOMAS, ANNA MARIA TEMPCZYK-RUSSELL, MICHAEL DAVID VARNEY, MICHAEL RAYMOND COLLINS, JOHN F. BRAGANZA
Year of Publication 15.06.2012
Get full text
Year of Publication 15.06.2012
Patent
INDAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PROTEIN KINASES, AND METHODS FOR THEIR USE
JOHNSON, Michael, David, BORCHARDT, Allen, J, BENDER, Steven, Lee, TENG, Min, LUU, Hiep, The, THOMAS, Christine, JOHNSON, Theodore, Otto, Jr, BRAGANZA, John, F, REICH, Siegfried, Heinz, HUA, Ye, WALLACE, Michael, Brennan, KANIA, Robert, Steven, TEMPCZYK-RUSSELL, Anna, Maria, VARNEY, Michael, David, PALMER, Cynthia, Louise, CRIPPS, Stephan, James, COLLINS, Michael, Raymond
Year of Publication 10.05.2011
Get full text
Year of Publication 10.05.2011
Patent
compostos de indazol ou sal farmaceuticamente aceitável e composição farmacêutica
THEODORE OTTO JOHNSON JR, SIEGFRIED HEINZ REICH, MIN TENG, YE HUA, ALLEN J. BORCHARDT, CYNTHIA LOUISE PALMER, MICHAEL DAVID JOHNSON, ROBERT STEVEN KANIA, ANNA MARIA TEMPCZYK-RUSSEL, MICHAEL BRENNAN WALLACE, STEVEN LEE BENDER, STEPHAN JAMES CRIPPS, CHRISTINE THOMAS, HIEP THE LUU, MICHAEL DAVID VARNEY, MICHAEL RAYMOND COLLINS, JOHN F. BRAGANZA
Year of Publication 16.08.2016
Get full text
Year of Publication 16.08.2016
Patent
INDAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PROTEIN KINASES, AND METHODS FOR THEIR USE
THEODORE OTTO JOHNSON JR, MIN TENG, YE HUA, CYNTHIA LOUISE PALMER, ALLEN J. BORCHARDT, ROBERT STEVEN KANIA, MICHAEL DAVID JOHNSON, MICHAEL BRENNAN WALLACE, STEVEN LEE BENDER, SEIGFRIED HEINZ REICH, STEPHAN JAMES CRIPPS, CHRISTINE THOMAS, HIEP THE LUU, ANNA MARIA TEMPCZYK-RUSSELL, MICHAEL DAVID VARNEY, JOHN F. BRAGANZA
Year of Publication 30.11.2009
Get full text
Year of Publication 30.11.2009
Patent
Indazole compounds and pharmaceutical compositionsfor inhibiting protein kinases, and methods for t heir use
ROBERT STEVEN KANIA, MICHAEL DAVID JOHNSON, BRAGANZA, JOHN, F, STEVEN LEE BENDER, STEPHAN JAMES CRIPPS, YE HUA, JOHNSON, THEODORE OTTO, JR, BORCHARDT, ALLEN, J
Year of Publication 18.04.2006
Get full text
Year of Publication 18.04.2006
Patent
Indazole compound, its use for treatment of mammalian disease and pharmaceutical preparation in which it is comprised
JOHNSON MICHAEL DAVID, LUU HIEP THE, PALMER CYNTHIA LOUISE, BORCHARDT ALLEN J, BRAGANZA JOHN F, KANIA ROBERT STEVEN, VARNEY MICHAEL DAVID, BENDER STEVEN LEE, TENG MIN, HUA YE, THOMAS CHRISTINE, JOHNSON THEODORE OTTO JR, REICH SIEGFRIED HEINZ, CRIPPS STEPHAN JAMES, WALLACE MICHAEL BRENNAN, COLLINS MICHAEL RAYMOND, TEMPCZYK-RUSSELL ANNA MARIA
Year of Publication 06.07.2009
Get full text
Year of Publication 06.07.2009
Patent