HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency
Schaller, Torsten, Ocwieja, Karen E, Rasaiyaah, Jane, Price, Amanda J, Brady, Troy L, Roth, Shoshannah L, Hué, Stéphane, Fletcher, Adam J, Lee, KyeongEun, KewalRamani, Vineet N, Noursadeghi, Mahdad, Jenner, Richard G, James, Leo C, Bushman, Frederic D, Towers, Greg J
Published in PLoS pathogens (01.12.2011)
Published in PLoS pathogens (01.12.2011)
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HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2
Ocwieja, Karen E, Brady, Troy L, Ronen, Keshet, Huegel, Alyssa, Roth, Shoshannah L, Schaller, Torsten, James, Leo C, Towers, Greg J, Young, John A T, Chanda, Sumit K, König, Renate, Malani, Nirav, Berry, Charles C, Bushman, Frederic D
Published in PLoS pathogens (01.03.2011)
Published in PLoS pathogens (01.03.2011)
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Decade-long safety and function of retroviral-modified chimeric antigen receptor T cells
Scholler, John, Brady, Troy L, Binder-Scholl, Gwendolyn, Hwang, Wei-Ting, Plesa, Gabriela, Hege, Kristen M, Vogel, Ashley N, Kalos, Michael, Riley, James L, Deeks, Steven G, Mitsuyasu, Ronald T, Bernstein, Wendy B, Aronson, Naomi E, Levine, Bruce L, Bushman, Frederic D, June, Carl H
Published in Science translational medicine (02.05.2012)
Published in Science translational medicine (02.05.2012)
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piggyBac transposase tools for genome engineering
Li, Xianghong, Burnight, Erin R, Cooney, Ashley L, Malani, Nirav, Brady, Troy, Sander, Jeffry D, Staber, Janice, Wheelan, Sarah J, Joung, J Keith, McCray, Jr, Paul B, Bushman, Frederic D, Sinn, Patrick L, Craig, Nancy L
Published in Proceedings of the National Academy of Sciences - PNAS (18.06.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (18.06.2013)
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Directly infected resting CD4+T cells can produce HIV Gag without spreading infection in a model of HIV latency
Pace, Matthew J, Graf, Erin H, Agosto, Luis M, Mexas, Angela M, Male, Frances, Brady, Troy, Bushman, Frederic D, O'Doherty, Una
Published in PLoS pathogens (01.07.2012)
Published in PLoS pathogens (01.07.2012)
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Phosphorylation Regulates Integration of the Yeast Ty5 Retrotransposon into Heterochromatin
Dai, Junbiao, Xie, Weiwu, Brady, Troy L., Gao, Jiquan, Voytas, Daniel F.
Published in Molecular cell (20.07.2007)
Published in Molecular cell (20.07.2007)
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Integration target site selection by a resurrected human endogenous retrovirus
Brady, Troy, Lee, Young Nam, Ronen, Keshet, Malani, Nirav, Berry, Charles C, Bieniasz, Paul D, Bushman, Frederic D
Published in Genes & development (01.03.2009)
Published in Genes & development (01.03.2009)
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A method to sequence and quantify DNA integration for monitoring outcome in gene therapy
Brady, Troy, Roth, Shoshannah L., Malani, Nirav, Wang, Gary P., Berry, Charles C., Leboulch, Philippe, Hacein-Bey-Abina, Salima, Cavazzana-Calvo, Marina, Papapetrou, Eirini P., Sadelain, Michel, Savilahti, Harri, Bushman, Frederic D.
Published in Nucleic acids research (01.06.2011)
Published in Nucleic acids research (01.06.2011)
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Recombinant adeno-associated virus integration sites in murine liver after ornithine transcarbamylase gene correction
Zhong, Li, Malani, Nirav, Li, Mengxin, Brady, Troy, Xie, Jun, Bell, Peter, Li, Shaoyong, Jones, Haven, Wilson, James M, Flotte, Terence R, Bushman, Frederic D, Gao, Guangping
Published in Human gene therapy (01.05.2013)
Published in Human gene therapy (01.05.2013)
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Journal Article
Allosteric Inhibition of Human Immunodeficiency Virus Integrase
Gupta, Kushol, Brady, Troy, Dyer, Benjamin M., Malani, Nirav, Hwang, Young, Male, Frances, Nolte, Robert T., Wang, Liping, Velthuisen, Emile, Jeffrey, Jerry, Van Duyne, Gregory D., Bushman, Frederic D.
Published in The Journal of biological chemistry (01.07.2014)
Published in The Journal of biological chemistry (01.07.2014)
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Retrotransposon Target Site Selection by Imitation of a Cellular Protein
Brady, Troy L., Fuerst, Peter G., Dick, Robert A., Schmidt, Clarice, Voytas, Daniel F.
Published in Molecular and Cellular Biology (01.02.2008)
Published in Molecular and Cellular Biology (01.02.2008)
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Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia
Cavazzana-Calvo, Marina, Payen, Emmanuel, Negre, Olivier, Wang, Gary, Hehir, Kathleen, Fusil, Floriane, Down, Julian, Denaro, Maria, Brady, Troy, Westerman, Karen, Cavallesco, Resy, Gillet-Legrand, Beatrix, Caccavelli, Laure, Sgarra, Riccardo, Maouche-Chrétien, Leila, Bernaudin, Françoise, Girot, Robert, Dorazio, Ronald, Mulder, Geert-Jan, Polack, Axel, Bank, Arthur, Soulier, Jean, Larghero, Jérôme, Kabbara, Nabil, Dalle, Bruno, Gourmel, Bernard, Socie, Gérard, Chrétien, Stany, Cartier, Nathalie, Aubourg, Patrick, Fischer, Alain, Cornetta, Kenneth, Galacteros, Frédéric, Beuzard, Yves, Gluckman, Eliane, Bushman, Frederick, Hacein-Bey-Abina, Salima, Leboulch, Philippe
Published in Nature (London) (16.09.2010)
Published in Nature (London) (16.09.2010)
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HIV integration site distributions in resting and activated CD4+ T cells infected in culture
BRADY, Troy, AGOSTO, Luis M, MALANI, Nirav, BERRY, Charles C, O'DOHERTY, Una, BUSHMAN, Frederic
Published in AIDS (London) (31.07.2009)
Published in AIDS (London) (31.07.2009)
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Allosteric inhibition of human immunodeficiency virus integrase: late block during viral replication and abnormal multimerization involving specific protein domains
Gupta, Kushol, Brady, Troy, Dyer, Benjamin M, Malani, Nirav, Hwang, Young, Male, Frances, Nolte, Robert T, Wang, Liping, Velthuisen, Emile, Jeffrey, Jerry, Van Duyne, Gregory D, Bushman, Frederic D
Published in The Journal of biological chemistry (25.07.2014)
Published in The Journal of biological chemistry (25.07.2014)
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Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIV
Tebas, Pablo, Stein, David, Binder-Scholl, Gwendolyn, Mukherjee, Rithun, Brady, Troy, Rebello, Tessio, Humeau, Laurent, Kalos, Michael, Papasavvas, Emmanouil, Montaner, Luis J., Schullery, Daniel, Shaheen, Farida, Brennan, Andrea L., Zheng, Zhaohui, Cotte, Julio, Slepushkin, Vladimir, Veloso, Elizabeth, Mackley, Adonna, Hwang, Wei-Ting, Aberra, Faten, Zhan, Jenny, Boyer, Jean, Collman, Ronald G., Bushman, Frederic D., Levine, Bruce L., June, Carl H.
Published in Blood (28.02.2013)
Published in Blood (28.02.2013)
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Distribution of Lentiviral Vector Integration Sites in Mice Following Therapeutic Gene Transfer to Treat β-thalassemia
Ronen, Keshet, Negre, Olivier, Roth, Shannah, Colomb, Charlotte, Malani, Nirav, Denaro, Maria, Brady, Troy, Fusil, Floriane, Gillet-Legrand, Beatrix, Hehir, Kathleen, Beuzard, Yves, Leboulch, Philippe, Down, Julian D, Payen, Emmanuel, Bushman, Frederic D
Published in Molecular therapy (01.07.2011)
Published in Molecular therapy (01.07.2011)
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Quantitation of HIV DNA integration: Effects of differential integration site distributions on Alu-PCR assays
Brady, Troy, Kelly, Brendan J., Male, Frances, Roth, Shoshannah, Bailey, Aubrey, Malani, Nirav, Gijsbers, Rik, O’Doherty, Una, Bushman, Frederic D.
Published in Journal of virological methods (01.04.2013)
Published in Journal of virological methods (01.04.2013)
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Methods for integration site distribution analyses in animal cell genomes
Ciuffi, Angela, Ronen, Keshet, Brady, Troy, Malani, Nirav, Wang, Gary, Berry, Charles C., Bushman, Frederic D.
Published in Methods (San Diego, Calif.) (01.04.2009)
Published in Methods (San Diego, Calif.) (01.04.2009)
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