Encapsulation state of messenger RNA inside lipid nanoparticles
Brader, Mark L., Williams, Sean J., Banks, Jessica M., Hui, Wong H., Zhou, Z. Hong, Jin, Lin
Published in Biophysical journal (20.07.2021)
Published in Biophysical journal (20.07.2021)
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Journal Article
Examination of Thermal Unfolding and Aggregation Profiles of a Series of Developable Therapeutic Monoclonal Antibodies
Brader, Mark L, Estey, Tia, Bai, Shujun, Alston, Roy W, Lucas, Karin K, Lantz, Steven, Landsman, Pavel, Maloney, Kevin M
Published in Molecular pharmaceutics (06.04.2015)
Published in Molecular pharmaceutics (06.04.2015)
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Journal Article
Fragmentation of a highly purified monoclonal antibody attributed to residual CHO cell protease activity
Gao, Sharon X., Zhang, Ying, Stansberry-Perkins, Kensey, Buko, Alex, Bai, Shujun, Nguyen, Vanessa, Brader, Mark L.
Published in Biotechnology and bioengineering (01.04.2011)
Published in Biotechnology and bioengineering (01.04.2011)
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Journal Article
Using X-Ray Crystallography to Simplify and Accelerate Biologics Drug Development
Brader, Mark L., Baker, Edward N., Dunn, Michael F., Laue, Thomas M., Carpenter, John F.
Published in Journal of pharmaceutical sciences (01.02.2017)
Published in Journal of pharmaceutical sciences (01.02.2017)
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Journal Article
Quantitation of Aggregate Levels in a Recombinant Humanized Monoclonal Antibody Formulation by Size-Exclusion Chromatography, Asymmetrical Flow Field Flow Fractionation, and Sedimentation Velocity
Gabrielson, John P., Brader, Mark L., Pekar, Allen H., Mathis, Kathrin B., Winter, Gerhard, Carpenter, John F., Randolph, Theodore W.
Published in Journal of pharmaceutical sciences (01.02.2007)
Published in Journal of pharmaceutical sciences (01.02.2007)
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Journal Article
A Biopharmaceutical Perspective on Higher-Order Structure and Thermal Stability of mRNA Vaccines
Kloczewiak, Marek, Banks, Jessica M., Jin, Lin, Brader, Mark L.
Published in Molecular pharmaceutics (04.07.2022)
Published in Molecular pharmaceutics (04.07.2022)
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Journal Article
Angle-dependent effects in DLS measurements of polydisperse particles
Jin, Lin, Jarand, Curtis W, Brader, Mark L, Reed, Wayne F
Published in Measurement science & technology (01.04.2022)
Published in Measurement science & technology (01.04.2022)
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Journal Article
Evaluation of Incremental Siliconization Levels on Soluble Aggregates, Submicron and Subvisible Particles in a Prefilled Syringe Product
Bai, Shujun, Landsman, Pavel, Spencer, Andrea, DeCollibus, Daniel, Vega, Fabian, Temel, Deniz B., Houde, Damian, Henderson, Olivia, Brader, Mark L.
Published in Journal of pharmaceutical sciences (01.01.2016)
Published in Journal of pharmaceutical sciences (01.01.2016)
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Journal Article
Monitoring protein aggregation kinetics with simultaneous multiple sample light scattering
Drenski, Michael F., Brader, Mark L., Alston, Roy W., Reed, Wayne F.
Published in Analytical biochemistry (15.06.2013)
Published in Analytical biochemistry (15.06.2013)
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Journal Article
Effects of Submicron Particles on Formation of Micron-Sized Particles During Long-Term Storage of an Interferon-Beta-1a Solution
Bai, Shujun, Murugesan, Yogapriya, Vlasic, Milana, Karpes, Lori B., Brader, Mark L.
Published in Journal of pharmaceutical sciences (01.02.2013)
Published in Journal of pharmaceutical sciences (01.02.2013)
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Journal Article
Calcium Binding to a Factor IX Fc Fusion Protein and Effects on Higher‐Order Structure
Li, Hao, Bai, Shufeng, Wei, Julie Y., Berkowitz, Steven A., Brader, Mark L.
Published in Journal of pharmaceutical sciences (01.11.2011)
Published in Journal of pharmaceutical sciences (01.11.2011)
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Journal Article
Hybrid insulin cocrystals for controlled release delivery
Brader, Mark L, Myers, Sharon R, Sukumar, Muppalla, Pekar, Allen H, McClellan, David S, Chance, Ronald E, Flora, David B, Cox, Amy L, Irwin, Lynnie
Published in Nature biotechnology (01.08.2002)
Published in Nature biotechnology (01.08.2002)
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Journal Article
Biophysical signatures of noncovalent aggregates formed by a glucagonlike peptide-1 analog: A prototypical example of biopharmaceutical aggregation
Doyle, Brandon L., Pollo, Mark J., Pekar, Allen H., Roy, Michael L., Thomas, Beth Ann, Brader, Mark L.
Published in Journal of pharmaceutical sciences (01.12.2005)
Published in Journal of pharmaceutical sciences (01.12.2005)
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Journal Article
Evaluation of Incremental Siliconization Levels on Soluble Aggregates, Submicron and Subvisible Particles in a Prefilled Syringe Product: Pharmaceutical Biotechnology
Bai, Shujun, Landsman, Pavel, Spencer, Andrea, DeCollibus, Daniel, Vega, Fabian, Temel, Deniz B, Houde, Damian, Henderson, Olivia, Brader, Mark L
Published in Journal of pharmaceutical sciences (01.01.2016)
Published in Journal of pharmaceutical sciences (01.01.2016)
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Journal Article
Ligand Perturbation Effects on a Pseudotetrahedral Co(II)(His)3-Ligand Site
Brader, Mark L., Kaarsholm, Niels C., Harnung, Sven E., Dunn, Michael F.
Published in The Journal of biological chemistry (10.01.1997)
Published in The Journal of biological chemistry (10.01.1997)
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Journal Article