Discovery and Characterization of the Potent and Selective P2X4 Inhibitor N‑[4-(3-Chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide (BAY-1797) and Structure-Guided Amelioration of Its CYP3A4 Induction Profile
Werner, Stefan, Mesch, Stefanie, Hillig, Roman C, ter Laak, Antonius, Klint, Julie, Neagoe, Ioana, Laux-Biehlmann, Alexis, Dahllöf, Henrik, Bräuer, Nico, Puetter, Vera, Nubbemeyer, Reinhard, Schulz, Simone, Bairlein, Michaela, Zollner, Thomas M, Steinmeyer, Andreas
Published in Journal of medicinal chemistry (26.12.2019)
Published in Journal of medicinal chemistry (26.12.2019)
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Eliapixant is a selective P2X3 receptor antagonist for the treatment of disorders associated with hypersensitive nerve fibers
Davenport, Adam J., Neagoe, Ioana, Bräuer, Nico, Koch, Markus, Rotgeri, Andrea, Nagel, Jens, Laux-Biehlmann, Alexis, Machet, Frederic, Coelho, Anne-Marie, Boyce, Susan, Carty, Nikisha, Gemkow, Mark J., Hess, Stephen D., Zollner, Thomas M., Fischer, Oliver M.
Published in Scientific reports (06.10.2021)
Published in Scientific reports (06.10.2021)
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Identification of a Benzimidazolecarboxylic Acid Derivative (BAY 1316957) as a Potent and Selective Human Prostaglandin E2 Receptor Subtype 4 (hEP4-R) Antagonist for the Treatment of Endometriosis
Bäurle, Stefan, Nagel, Jens, Peters, Olaf, Bräuer, Nico, ter Laak, Antonius, Preusse, Cornelia, Rottmann, Antje, Heldmann, Dieter, Bothe, Ulrich, Blume, Thorsten, Zorn, Ludwig, Walter, Daryl, Zollner, Thomas M, Steinmeyer, Andreas, Langer, Gernot
Published in Journal of medicinal chemistry (14.03.2019)
Published in Journal of medicinal chemistry (14.03.2019)
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Discovery and Characterization of the Potent and Highly Selective 1,7-Naphthyridine-Based Inhibitors BAY-091 and BAY-297 of the Kinase PIP4K2A
Wortmann, Lars, Bräuer, Nico, Holton, Simon J, Irlbacher, Horst, Weiske, Jörg, Lechner, Christian, Meier, Robin, Karén, Jakob, Siöberg, Catrine Berthold, Pütter, Vera, Christ, Clara D, ter Laak, Antonius, Lienau, Philip, Lesche, Ralf, Nicke, Barbara, Cheung, Shing-Hu, Bauser, Marcus, Haegebarth, Andrea, von Nussbaum, Franz, Mumberg, Dominik, Lemos, Clara
Published in Journal of medicinal chemistry (11.11.2021)
Published in Journal of medicinal chemistry (11.11.2021)
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Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists BAY-4931 and BAY-0069
Orsi, Douglas L., Pook, Elisabeth, Bräuer, Nico, Friberg, Anders, Lienau, Philip, Lemke, Christopher T., Stellfeld, Timo, Brüggemeier, Ulf, Pütter, Vera, Meyer, Hanna, Baco, Maria, Tang, Stephanie, Cherniack, Andrew D., Westlake, Lindsay, Bender, Samantha A., Kocak, Mustafa, Strathdee, Craig A., Meyerson, Matthew, Eis, Knut, Goldstein, Jonathan T.
Published in Journal of medicinal chemistry (10.11.2022)
Published in Journal of medicinal chemistry (10.11.2022)
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Correction to “Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists BAY-4931 and BAY-0069”
Orsi, Douglas L., Pook, Elisabeth, Bräuer, Nico, Friberg, Anders, Lienau, Philip, Lemke, Christopher T., Stellfeld, Timo, Brüggemeier, Ulf, Pütter, Vera, Meyer, Hanna, Baco, Maria, Tang, Stephanie, Cherniack, Andrew D., Westlake, Lindsay, Bender, Samantha A., Kocak, Mustafa, Strathdee, Craig A., Meyerson, Matthew, Eis, Knut, Goldstein, Jonathan T.
Published in Journal of medicinal chemistry (12.01.2023)
Published in Journal of medicinal chemistry (12.01.2023)
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Discovery and optimization of pyridyl-cycloalkyl-carboxylic acids as inhibitors of microsomal prostaglandin E synthase-1 for the treatment of endometriosis
Koppitz, Marcus, Bräuer, Nico, Ter Laak, Antonius, Irlbacher, Horst, Rotgeri, Andrea, Coelho, Anne-Marie, Walter, Daryl, Steinmeyer, Andreas, Zollner, Thomas M., Peters, Michaele, Nagel, Jens
Published in Bioorganic & medicinal chemistry letters (15.09.2019)
Published in Bioorganic & medicinal chemistry letters (15.09.2019)
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TEAD INHIBITORS
WEISKE, Jörg, DIERKS, Paul, LANGE, Martin, BRÄUER, Nico, BUNSE, Stefanie, BARAK, Naomi, LECHNER, Christian, HILLIG, Roman, BLUCK, Joseph, GRÜNEWALD, Sylvia
Year of Publication 04.01.2024
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Year of Publication 04.01.2024
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UREA DERIVATIVES FOR USE AGAINST PROLIFERATIVE DISEASES
GORJANACZ, Matyas, EHRMANN, Alexander, STRESEMANN, Carlo, BRÄUER, Nico
Year of Publication 30.07.2020
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Year of Publication 30.07.2020
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UREA DERIVATIVES
GORJANACZ, Matyas, EHRMANN, Alexander, STRESEMANN, Carlo, BRÄUER, Nico
Year of Publication 25.06.2020
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Year of Publication 25.06.2020
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A Silicon-Mediated Synthesis of 3-Deoxy-D-manno-octulosonic Acid (KDO)
Bräuer, Nico, Kirschning, Andreas, Schaumann, Ernst
Published in European journal of organic chemistry (01.12.1998)
Published in European journal of organic chemistry (01.12.1998)
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COMPOUNDS AND METHODS OF ACTIVATING LIPOPROTEIN LIPASE
TESTOLIN, Giambattista, BLIZZARD, Timothy, DEWEY, Frederick, BRÄUER, Nico, LECHNER, Christian, KONSTANTINOVIĆ, Jelena, DA SILVA JARDINE, Paul
Year of Publication 28.07.2022
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Year of Publication 28.07.2022
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1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES
GODINHO-COELHO, Anne-Marie, FISCHER, Oliver Martin, ROTGERI, Andrea, BRÄUER, Nico, NAGEL, Jens, NEAGOE, Ioana, DAVENPORT, Adam James, ROTTMANN, Antje, KLAR, Jürgen
Year of Publication 23.02.2023
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Year of Publication 23.02.2023
Patent
Aromatic sulfonamide derivatives
Werner, Stefan, Hardaker, Elizabeth, Herbert, Simon Anthony, Lishchynskyi, Anton, Koch, Markus, Dahllöf, Henrik, Osmers, Maren, Bräuer, Nico, Cleve, Arwed, Mesch, Stefanie
Year of Publication 13.12.2022
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Year of Publication 13.12.2022
Patent
Benzamides substitués 1,3-thiazol-2-yl
Godinho-Coelho, Anne-Marie, Fischer, Oliver Martin, Klar, Jürgen, Nagel, Jens, Neagoe, Ioana, Davenport, Adam, Rotgeri, Andrea, Bräuer, Nico, Rottmann, Antje
Year of Publication 30.11.2022
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Year of Publication 30.11.2022
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