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VanAernum, Zachary L, Busch, Florian, Jones, Benjamin J, Jia, Mengxuan, Chen, Zibo, Boyken, Scott E, Sahasrabuddhe, Aniruddha, Baker, David, Wysocki, Vicki H
Published in Nature protocols (01.03.2020)
Published in Nature protocols (01.03.2020)
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De novo design of modular and tunable protein biosensors
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Published in Nature (London) (18.03.2021)
Published in Nature (London) (18.03.2021)
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De novo design of protein logic gates
Chen, Zibo, Kibler, Ryan D, Hunt, Andrew, Busch, Florian, Pearl, Jocelynn, Jia, Mengxuan, VanAernum, Zachary L, Wicky, Basile I M, Dods, Galen, Liao, Hanna, Wilken, Matthew S, Ciarlo, Christie, Green, Shon, El-Samad, Hana, Stamatoyannopoulos, John, Wysocki, Vicki H, Jewett, Michael C, Boyken, Scott E, Baker, David
Published in Science (American Association for the Advancement of Science) (03.04.2020)
Published in Science (American Association for the Advancement of Science) (03.04.2020)
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Accurate computational design of multipass transmembrane proteins
Lu, Peilong, Min, Duyoung, DiMaio, Frank, Wei, Kathy Y, Vahey, Michael D, Boyken, Scott E, Chen, Zibo, Fallas, Jorge A, Ueda, George, Sheffler, William, Mulligan, Vikram Khipple, Xu, Wenqing, Bowie, James U, Baker, David
Published in Science (American Association for the Advancement of Science) (02.03.2018)
Published in Science (American Association for the Advancement of Science) (02.03.2018)
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De novo design of bioactive protein switches
Langan, Robert A, Boyken, Scott E, Ng, Andrew H, Samson, Jennifer A, Dods, Galen, Westbrook, Alexandra M, Nguyen, Taylor H, Lajoie, Marc J, Chen, Zibo, Berger, Stephanie, Mulligan, Vikram Khipple, Dueber, John E, Novak, Walter R P, El-Samad, Hana, Baker, David
Published in Nature (London) (01.08.2019)
Published in Nature (London) (01.08.2019)
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Rapid Sampling of Hydrogen Bond Networks for Computational Protein Design
Maguire, Jack B, Boyken, Scott E, Baker, David, Kuhlman, Brian
Published in Journal of chemical theory and computation (08.05.2018)
Published in Journal of chemical theory and computation (08.05.2018)
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Designed protein logic to target cells with precise combinations of surface antigens
Lajoie, Marc J, Boyken, Scott E, Salter, Alexander I, Bruffey, Jilliane, Rajan, Anusha, Langan, Robert A, Olshefsky, Audrey, Muhunthan, Vishaka, Bick, Matthew J, Gewe, Mesfin, Quijano-Rubio, Alfredo, Johnson, JayLee, Lenz, Garreck, Nguyen, Alisha, Pun, Suzie, Correnti, Colin E, Riddell, Stanley R, Baker, David
Published in Science (American Association for the Advancement of Science) (25.09.2020)
Published in Science (American Association for the Advancement of Science) (25.09.2020)
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De novo design of tunable, pH-driven conformational changes
Boyken, Scott E, Benhaim, Mark A, Busch, Florian, Jia, Mengxuan, Bick, Matthew J, Choi, Heejun, Klima, Jason C, Chen, Zibo, Walkey, Carl, Mileant, Alexander, Sahasrabuddhe, Aniruddha, Wei, Kathy Y, Hodge, Edgar A, Byron, Sarah, Quijano-Rubio, Alfredo, Sankaran, Banumathi, King, Neil P, Lippincott-Schwartz, Jennifer, Wysocki, Vicki H, Lee, Kelly K, Baker, David
Published in Science (American Association for the Advancement of Science) (17.05.2019)
Published in Science (American Association for the Advancement of Science) (17.05.2019)
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Computational design of transmembrane pores
Xu, Chunfu, Lu, Peilong, Gamal El-Din, Tamer M, Pei, Xue Y, Johnson, Matthew C, Uyeda, Atsuko, Bick, Matthew J, Xu, Qi, Jiang, Daohua, Bai, Hua, Reggiano, Gabriella, Hsia, Yang, Brunette, T J, Dou, Jiayi, Ma, Dan, Lynch, Eric M, Boyken, Scott E, Huang, Po-Ssu, Stewart, Lance, DiMaio, Frank, Kollman, Justin M, Luisi, Ben F, Matsuura, Tomoaki, Catterall, William A, Baker, David
Published in Nature (London) (03.09.2020)
Published in Nature (London) (03.09.2020)
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Programmable design of orthogonal protein heterodimers
Chen, Zibo, Boyken, Scott E, Jia, Mengxuan, Busch, Florian, Flores-Solis, David, Bick, Matthew J, Lu, Peilong, VanAernum, Zachary L, Sahasrabuddhe, Aniruddha, Langan, Robert A, Bermeo, Sherry, Brunette, T J, Mulligan, Vikram Khipple, Carter, Lauren P, DiMaio, Frank, Sgourakis, Nikolaos G, Wysocki, Vicki H, Baker, David
Published in Nature (London) (01.01.2019)
Published in Nature (London) (01.01.2019)
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Modular and tunable biological feedback control using a de novo protein switch
Ng, Andrew H, Nguyen, Taylor H, Gómez-Schiavon, Mariana, Dods, Galen, Langan, Robert A, Boyken, Scott E, Samson, Jennifer A, Waldburger, Lucas M, Dueber, John E, Baker, David, El-Samad, Hana
Published in Nature (London) (01.08.2019)
Published in Nature (London) (01.08.2019)
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De novo design of protein homo-oligomers with modular hydrogen-bond network–mediated specificity
Boyken, Scott E., Chen, Zibo, Groves, Benjamin, Langan, Robert A., Oberdorfer, Gustav, Ford, Alex, Gilmore, Jason M., Xu, Chunfu, DiMaio, Frank, Pereira, Jose Henrique, Sankaran, Banumathi, Seelig, Georg, Zwart, Peter H., Baker, David
Published in Science (American Association for the Advancement of Science) (06.05.2016)
Published in Science (American Association for the Advancement of Science) (06.05.2016)
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Dynamic Allostery Mediated by a Conserved Tryptophan in the Tec Family Kinases
Chopra, Nikita, Wales, Thomas E, Joseph, Raji E, Boyken, Scott E, Engen, John R, Jernigan, Robert L, Andreotti, Amy H
Published in PLoS computational biology (01.03.2016)
Published in PLoS computational biology (01.03.2016)
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Design and structure of two new protein cages illustrate successes and ongoing challenges in protein engineering
Cannon, Kevin A., Park, Rachel U., Boyken, Scott E., Nattermann, Una, Yi, Sue, Baker, David, King, Neil P., Yeates, Todd O.
Published in Protein science (01.04.2020)
Published in Protein science (01.04.2020)
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Computational design of closely related proteins that adopt two well-defined but structurally divergent folds
Wei, Kathy Y., Moschidi, Danai, Bick, Matthew J., Nerli, Santrupti, McShan, Andrew C., Carter, Lauren P., Huang, Po-Ssu, Fletcher, Daniel A., Sgourakis, Nikolaos G., Boyken, Scott E., Baker, David
Published in Proceedings of the National Academy of Sciences - PNAS (31.03.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (31.03.2020)
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Self-Assembling 2D Arrays with de Novo Protein Building Blocks
Chen, Zibo, Johnson, Matthew C, Chen, Jiajun, Bick, Matthew J, Boyken, Scott E, Lin, Baihan, De Yoreo, James J, Kollman, Justin M, Baker, David, DiMaio, Frank
Published in Journal of the American Chemical Society (05.06.2019)
Published in Journal of the American Chemical Society (05.06.2019)
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Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice
Hunt, Andrew C, Case, James Brett, Park, Young-Jun, Cao, Longxing, Wu, Kejia, Walls, Alexandra C, Liu, Zhuoming, Bowen, John E, Yeh, Hsien-Wei, Saini, Shally, Helms, Louisa, Zhao, Yan Ting, Hsiang, Tien-Ying, Starr, Tyler N, Goreshnik, Inna, Kozodoy, Lisa, Carter, Lauren, Ravichandran, Rashmi, Green, Lydia B, Matochko, Wadim L, Thomson, Christy A, Vögeli, Bastian, Krüger, Antje, VanBlargan, Laura A, Chen, Rita E, Ying, Baoling, Bailey, Adam L, Kafai, Natasha M, Boyken, Scott E, Ljubetič, Ajasja, Edman, Natasha, Ueda, George, Chow, Cameron M, Johnson, Max, Addetia, Amin, Navarro, Mary-Jane, Panpradist, Nuttada, Gale, Jr, Michael, Freedman, Benjamin S, Bloom, Jesse D, Ruohola-Baker, Hannele, Whelan, Sean P J, Stewart, Lance, Diamond, Michael S, Veesler, David, Jewett, Michael C, Baker, David
Published in Science translational medicine (25.05.2022)
Published in Science translational medicine (25.05.2022)
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De novo design of obligate ABC-type heterotrimeric proteins
Bermeo, Sherry, Favor, Andrew, Chang, Ya-Ting, Norris, Andrew, Boyken, Scott E, Hsia, Yang, Haddox, Hugh K, Xu, Chunfu, Brunette, T J, Wysocki, Vicki H, Bhabha, Gira, Ekiert, Damian C, Baker, David
Published in Nature structural & molecular biology (01.12.2022)
Published in Nature structural & molecular biology (01.12.2022)
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