Histamine H3 Receptor as a Drug Discovery Target
Berlin, Michael, Boyce, Christopher W, de Lera Ruiz, Manuel
Published in Journal of medicinal chemistry (13.01.2011)
Published in Journal of medicinal chemistry (13.01.2011)
Get full text
Journal Article
Total Syntheses of Ningalin A, Lamellarin O, Lukianol A, and Permethyl Storniamide A Utilizing Heterocyclic Azadiene Diels−Alder Reactions
Boger, Dale L, Boyce, Christopher W, Labroli, Marc A, Sehon, Clark A, Jin, Qing
Published in Journal of the American Chemical Society (13.01.1999)
Published in Journal of the American Chemical Society (13.01.1999)
Get full text
Journal Article
Pharmacological evaluation of selective α2c-adrenergic agonists in experimental animal models of nasal congestion
Jia, Yanlin, Mingo, Garfield G, Hunter, John C, Lieber, Gissela B, Palamanda, Jairam R, Mei, Hong, Boyce, Christopher W, Koss, Michael C, Yu, Yongxin, Cicmil, Milenko, Hey, John A, McLeod, Robbie L
Published in The Journal of pharmacology and experimental therapeutics (01.04.2014)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2014)
Get full text
Journal Article
CC-1065 and the Duocarmycins: Synthetic Studies
Boger, Dale L, Boyce, Christopher W, Garbaccio, Robert M, Goldberg, Joel A
Published in Chemical reviews (08.05.1997)
Published in Chemical reviews (08.05.1997)
Get full text
Journal Article
Total Synthesis of Ningalin B Utilizing a Heterocyclic Azadiene Diels−Alder Reaction and Discovery of a New Class of Potent Multidrug Resistant (MDR) Reversal Agents
Boger, Dale L, Soenen, Danielle R, Boyce, Christopher W, Hedrick, Michael P, Jin, Qing
Published in Journal of organic chemistry (21.04.2000)
Published in Journal of organic chemistry (21.04.2000)
Get full text
Journal Article
Evaluating Spray Drying and Co-Precipitation as Manufacturing Processes for Amorphous Solid Dispersions of a Low Tg API
Solomos, Marina A., Punia, Ashish, Saboo, Sugandha, John, Christopher, Boyce, Christopher W., Chin, Alexander, Taggart, Robert V., Smith, Daniel, Lamm, Matthew S., Schenck, Luke
Published in Journal of pharmaceutical sciences (01.08.2023)
Published in Journal of pharmaceutical sciences (01.08.2023)
Get full text
Journal Article
Activity of Tricyclic Pyrrolopyrimidine Gyrase B Inhibitor against Mycobacterium abscessus
Madani, Abdeldjalil, Negatu, Dereje A., El Marrouni, Abdellatif, Miller, Randy R., Boyce, Christopher W., Murgolo, Nicholas, Bungard, Christopher J., Zimmerman, Matthew D., Dartois, Véronique, Gengenbacher, Martin, Olsen, David B., Dick, Thomas
Published in Antimicrobial agents and chemotherapy (20.09.2022)
Published in Antimicrobial agents and chemotherapy (20.09.2022)
Get full text
Journal Article
The Invention of WM382, a Highly Potent PMIX/X Dual Inhibitor toward the Treatment of Malaria
de Lera Ruiz, Manuel, Favuzza, Paola, Guo, Zhuyan, Zhao, Lianyun, Hu, Bin, Lei, Zhiyu, Zhan, Dongmei, Murgolo, Nicholas, Boyce, Christopher W., Vavrek, Marissa, Thompson, Jennifer, Ngo, Anna, Jarman, Kate E., Robbins, Johnathan, Boddey, Justin, Sleebs, Brad E., Lowes, Kym N., Cowman, Alan F., Olsen, David B., McCauley, John A.
Published in ACS medicinal chemistry letters (10.11.2022)
Published in ACS medicinal chemistry letters (10.11.2022)
Get full text
Journal Article
Novel Pan-Coronavirus 3CL Protease Inhibitor MK-7845: Biological and Pharmacological Profiling
Alvarez, Nadine, Adam, Gregory C, Howe, John A, Sharma, Vijeta, Zimmerman, Matthew D, Dolgov, Enriko, Rasheed, Risha, Nizar, Fatima, Sahay, Khushboo, Nelson, Andrew M, Park, Steven, Zhou, Xiaoyan, Burlein, Christine, Fay, John F, Iwamoto, Daniel V, Bahnck-Teets, Carolyn M, Getty, Krista L, Lin Goh, Shih, Salhab, Imad, Smith, Keith, Boyce, Christopher W, Cabalu, Tamara D, Murgolo, Nicholas, Fox, Nicholas G, Mayhood, Todd W, Shurtleff, Valerie W, Layton, Mark E, Parish, Craig A, McCauley, John A, Olsen, David B, Perlin, David S
Published in Viruses (01.07.2024)
Published in Viruses (01.07.2024)
Get full text
Journal Article
Recent advances in the development of histamine H3 antagonists
Berlin, Michael, Boyce, Christopher W
Published in Expert opinion on therapeutic patents (01.06.2007)
Published in Expert opinion on therapeutic patents (01.06.2007)
Get more information
Journal Article
Synthesis and SAR studies of benzimidazolone derivatives as histamine H3-receptor antagonists
Zeng, Qingbei, Rosenblum, Stuart B., Yang, Zhaoxia, Jiang, Yueheng, McCormick, Kevin D., Aslanian, Robert G., Duguma, Luli, Kozlowski, Joseph A., Shih, Neng-Yang, Hey, John A., West, Robert E., Korfmacher, Walter A., Berlin, Michael, Boyce, Christopher W.
Published in Bioorganic & medicinal chemistry letters (01.11.2013)
Published in Bioorganic & medicinal chemistry letters (01.11.2013)
Get full text
Journal Article
Role of α2-adrenoceptors in electrical field stimulation-induced contraction of pig nasal mucosa and pharmacologic characterization of a novel α2C-adrenoceptor agonist
Corboz, Michel R, Rivelli, Maria A, Shah, Himanshu, Boyce, Christopher W, McCormick, Kevin D, Chapman, Richard W, Hunter, John C
Published in American journal of rhinology & allergy (01.03.2013)
Published in American journal of rhinology & allergy (01.03.2013)
Get more information
Journal Article
Reduction of hERG inhibitory activity in the 4-piperidinyl urea series of H3 antagonists
Berlin, Michael, Lee, Yoon Joo, Boyce, Christopher W., Wang, Yi, Aslanian, Robert, McCormick, Kevin D., Sorota, Steve, Williams, Shirley M., West, Robert E., Korfmacher, Walter
Published in Bioorganic & medicinal chemistry letters (01.04.2010)
Published in Bioorganic & medicinal chemistry letters (01.04.2010)
Get full text
Journal Article
Histamine H 3 Receptor as a Drug Discovery Target
Berlin, Michael, Boyce, Christopher W., de Lera Ruiz, Manuel
Published in Journal of medicinal chemistry (13.01.2011)
Published in Journal of medicinal chemistry (13.01.2011)
Get full text
Journal Article
Synthesis, Chemical Properties, and Preliminary Evaluation of Substituted CBI Analogs of CC-1065 and the Duocarmycins Incorporating the 7-Cyano-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one Alkylation Subunit: Hammett Quantitation of the Magnitude of Electronic Effects on Functional Reactivity
Boger, Dale L, Han, Nianhe, Tarby, Christine M, Boyce, Christopher W, Cai, Hui, Jin, Qing, Kitos, Paul A
Published in Journal of organic chemistry (26.07.1996)
Published in Journal of organic chemistry (26.07.1996)
Get full text
Journal Article
Invention of MK-7845, a SARS-CoV‑2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic
Shurtleff, Valerie W., Layton, Mark E., Parish, Craig A., Perkins, James J., Schreier, John D., Wang, Yunyi, Adam, Gregory C., Alvarez, Nadine, Bahmanjah, Soheila, Bahnck-Teets, Carolyn M., Boyce, Christopher W., Burlein, Christine, Cabalu, Tamara D., Campbell, Brian T., Carroll, Steven S., Chang, Wonsuk, de Lera Ruiz, Manuel, Dolgov, Enriko, Fay, John F., Fox, Nicholas G., Goh, Shih Lin, Hartingh, Timothy J., Hurzy, Danielle M., Kelly, Michael J., Klein, Daniel J., Klingler, Franca-Maria, Krishnamurthy, Harini, Kudalkar, Shalley, Mayhood, Todd W., McKenna, Philip M., Murray, Edward M., Nahas, Debbie, Nawrat, Christopher C., Park, Steven, Qian, Dongming, Roecker, Anthony J., Sharma, Vijeta, Shipe, William D., Su, Jing, Taggart, Robert V., Truong, Quang, Wu, Yin, Zhou, Xiaoyan, Zhuang, Ningning, Perlin, David S., Olsen, David B., Howe, John A., McCauley, John A.
Published in Journal of medicinal chemistry (14.03.2024)
Published in Journal of medicinal chemistry (14.03.2024)
Get full text
Journal Article
Evaluating Spray Drying and Co-Precipitation as Manufacturing Processes for Amorphous Solid Dispersions of a Low T g API
Solomos, Marina A, Punia, Ashish, Saboo, Sugandha, John, Christopher, Boyce, Christopher W, Chin, Alexander, Taggart, Robert V, Smith, Daniel, Lamm, Matthew S, Schenck, Luke
Published in Journal of pharmaceutical sciences (01.08.2023)
Get full text
Published in Journal of pharmaceutical sciences (01.08.2023)
Journal Article
QUINOXALINES AND AZA-QUINOXALINES AS CRTH2 RECEPTOR MODULATORS
QIN JUN, MAZZOLA ROBERT D. JR, LEYHANE ANDREW J, XIAO DONG, BOYCE CHRISTOPHER W, WU JIE, SILIPHAIVANH PHIENG, YU YOUNONG, ZHANG HONGJUN, MCCORMICK KEVIN D, HUANG XIANHAI, BIJU PURAKKATTLE JOHNY, METHOT JOEY LEE, RAO ASHWIN UMESH, JIANG QIN, DEGRADO SYLVIA JOANNA, GAUUAN JOLICIA POLIVINA, KELLEY ELIZABETH HELEN, PALANI ANANDAN, DONG LI, ASLANIAN ROBERT GEORGE, BROWN WILLIAM COLBY, FEVRIER SALEM, VACCARO HENRY M, CHEN XIAO, DHONDI PAWAN K
Year of Publication 06.12.2013
Get full text
Year of Publication 06.12.2013
Patent