IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases
Teng, Michele W L, Bowman, Edward P, McElwee, Joshua J, Smyth, Mark J, Casanova, Jean-Laurent, Cooper, Andrea M, Cua, Daniel J
Published in Nature medicine (01.07.2015)
Published in Nature medicine (01.07.2015)
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Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category
Luger, Dror, Silver, Phyllis B, Tang, Jun, Cua, Daniel, Chen, Zoe, Iwakura, Yoichiro, Bowman, Edward P, Sgambellone, Nicole M, Chan, Chi-Chao, Caspi, Rachel R
Published in The Journal of experimental medicine (14.04.2008)
Published in The Journal of experimental medicine (14.04.2008)
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Detection of cell–cell interactions via photocatalytic cell tagging
Oslund, Rob C., Reyes-Robles, Tamara, White, Cory H., Tomlinson, Jake H., Crotty, Kelly A., Bowman, Edward P., Chang, Dan, Peterson, Vanessa M., Li, Lixia, Frutos, Silvia, Vila-Perelló, Miquel, Vlerick, David, Cromie, Karen, Perlman, David H., Ingale, Sampat, Hara, Samantha D. O’, Roberts, Lee R., Piizzi, Grazia, Hett, Erik C., Hazuda, Daria J., Fadeyi, Olugbeminiyi O.
Published in Nature chemical biology (01.08.2022)
Published in Nature chemical biology (01.08.2022)
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IL-23 is critical for induction of arthritis, osteoclast formation, and maintenance of bone mass
Adamopoulos, Iannis E, Tessmer, Marlowe, Chao, Cheng-Chi, Adda, Sarvesh, Gorman, Dan, Petro, Mary, Chou, Chuan-Chu, Pierce, Robert H, Yao, Wei, Lane, Nancy E, Laface, Drake, Bowman, Edward P
Published in The Journal of immunology (1950) (15.07.2011)
Published in The Journal of immunology (1950) (15.07.2011)
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Dissociation of LAG-3 inhibitory cluster from TCR microcluster by immune checkpoint blockade
Hashimoto-Tane, Akiko, Bowman, Edward P, Sakuma, Machie, Yoneda, Natsumi, Yugi, Katsuyuki, de Waal Malefyt, Rene, Saito, Takashi
Published in Frontiers in immunology (21.08.2024)
Published in Frontiers in immunology (21.08.2024)
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Crosstalk among IL-23 and DNAX activating protein of 12 kDa-dependent pathways promotes osteoclastogenesis
Shin, Hyun-Seock, Sarin, Ritu, Dixit, Neha, Wu, Jian, Gershwin, Eric, Bowman, Edward P, Adamopoulos, Iannis E
Published in The Journal of immunology (1950) (01.01.2015)
Published in The Journal of immunology (1950) (01.01.2015)
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Regulation of Myeloid Cell Function through the CD200 Receptor
Jenmalm, Maria C, Cherwinski, Holly, Bowman, Edward P, Phillips, Joseph H, Sedgwick, Jonathon D
Published in Journal of Immunology (01.01.2006)
Published in Journal of Immunology (01.01.2006)
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CCR10 expression is a common feature of circulating and mucosal epithelial tissue IgA Ab-secreting cells
Kunkel, Eric J, Kim, Chang H, Lazarus, Nicole H, Vierra, Mark A, Soler, Dulce, Bowman, Edward P, Butcher, Eugene C
Published in The Journal of clinical investigation (01.04.2003)
Published in The Journal of clinical investigation (01.04.2003)
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Antitumor efficacy of combined CTLA4/PD-1 blockade without intestinal inflammation is achieved by elimination of FcγR interactions
Bauché, David, Mauze, Smita, Kochel, Christina, Grein, Jeff, Sawant, Anandi, Zybina, Yulia, Blumenschein, Wendy, Yang, Peng, Annamalai, Lakshmanan, Yearley, Jennifer H, Punnonen, Juha, Bowman, Edward P, Chackerian, Alissa, Laface, Drake
Published in Journal for immunotherapy of cancer (01.10.2020)
Published in Journal for immunotherapy of cancer (01.10.2020)
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The intestinal chemokine thymus-expressed chemokine (CCL25) attracts IgA antibody-secreting cells
Bowman, Edward P, Kuklin, Nelly A, Youngman, Kenneth R, Lazarus, Nicole H, Kunkel, Eric J, Pan, Junliang, Greenberg, Harry B, Butcher, Eugene C
Published in The Journal of experimental medicine (21.01.2002)
Published in The Journal of experimental medicine (21.01.2002)
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Anti-IL-17A therapy protects against bone erosion in experimental models of rheumatoid arthritis
Chao, Cheng-Chi, Chen, Shi-Juan, Adamopoulos, Iannis E., Davis, Nicole, Hong, Kyu, Vu, Anna, Kwan, Sylvia, Fayadat-Dilman, Laurence, Asio, Agelio, Bowman, Edward P.
Published in Autoimmunity (Chur, Switzerland) (01.05.2011)
Published in Autoimmunity (Chur, Switzerland) (01.05.2011)
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Neutralization or Absence of the Interleukin-23 Pathway Does Not Compromise Immunity to Mycobacterial Infection
Chackerian, Alissa A, Chen, Shi-Juan, Brodie, Scott J, Mattson, Jeanine D, McClanahan, Terrill K, Kastelein, Robert A, Bowman, Edward P
Published in Infection and Immunity (01.11.2006)
Published in Infection and Immunity (01.11.2006)
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IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4−CD8− entheseal resident T cells
Sherlock, Jonathan P, Joyce-Shaikh, Barbara, Turner, Scott P, Chao, Cheng-Chi, Sathe, Manjiri, Grein, Jeff, Gorman, Daniel M, Bowman, Edward P, McClanahan, Terrill K, Yearley, Jennifer H, Eberl, Gérard, Buckley, Christopher D, Kastelein, Robert A, Pierce, Robert H, LaFace, Drake M, Cua, Daniel J
Published in Nature medicine (01.07.2012)
Published in Nature medicine (01.07.2012)
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Dual Roles for Regulatory T-cell Depletion and Costimulatory Signaling in Agonistic GITR Targeting for Tumor Immunotherapy
Mahne, Ashley E, Mauze, Smita, Joyce-Shaikh, Barbara, Xia, Jane, Bowman, Edward P, Beebe, Amy M, Cua, Daniel J, Jain, Renu
Published in Cancer research (Chicago, Ill.) (01.03.2017)
Published in Cancer research (Chicago, Ill.) (01.03.2017)
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Journal Article
Clinical improvement in psoriasis with specific targeting of interleukin-23
Kopp, Tamara, Riedl, Elisabeth, Bangert, Christine, Bowman, Edward P., Greisenegger, Elli, Horowitz, Ann, Kittler, Harald, Blumenschein, Wendy M., McClanahan, Terrill K., Marbury, Thomas, Zachariae, Claus, Xu, Danlin, Hou, Xiaoli Shirley, Mehta, Anish, Zandvliet, Anthe S., Montgomery, Diana, van Aarle, Frank, Khalilieh, Sauzanne
Published in Nature (London) (14.05.2015)
Published in Nature (London) (14.05.2015)
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Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells
Lowes, Michelle A., Kikuchi, Toyoko, Fuentes-Duculan, Judilyn, Cardinale, Irma, Zaba, Lisa C., Haider, Asifa S., Bowman, Edward P., Krueger, James G.
Published in Journal of investigative dermatology (01.05.2008)
Published in Journal of investigative dermatology (01.05.2008)
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Biomarkers of Therapeutic Response in the IL-23 Pathway in Inflammatory Bowel Disease
Cayatte, Corinne, Joyce-Shaikh, Barbara, Vega, Felix, Boniface, Katia, Grein, Jeffrey, Murphy, Erin, Blumenschein, Wendy M, Chen, Smiley, Malinao, Maria-Christina, Basham, Beth, Pierce, Robert H, Bowman, Edward P, McKenzie, Brent S, Elson, Charles O, Faubion, William A, Malefyt, Rene de Waal, Kastelein, Robert A, Cua, Daniel, McClanahan, Terrill K, Beaumont, Maribel
Published in Clinical and translational gastroenterology (01.02.2012)
Published in Clinical and translational gastroenterology (01.02.2012)
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Development, cytokine profile and function of human interleukin 17-producing helper T cells
Boniface, Katia, Bowman, Edward P, Mattson, Jeanine D, Basham, Beth, Chen, Taiying, Smith, Kathleen, Kastelein, Robert A, Morel, Franck, Blumenschein, Wendy M, Cua, Daniel J, McClanahan, Terrill K, de Waal Malefyt, Rene, Wilson, Nicholas J, Lecron, Jean-Claude, McKenzie, Brent S, Chan, Jason R
Published in Nature Immunology (01.09.2007)
Published in Nature Immunology (01.09.2007)
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Interleukin-17A upregulates receptor activator of NF-κB on osteoclast precursors
Adamopoulos, Iannis E, Chao, Cheng-chi, Geissler, Richard, Laface, Drake, Blumenschein, Wendy, Iwakura, Yoichiro, McClanahan, Terrill, Bowman, Edward P
Published in Arthritis research & therapy (01.01.2010)
Published in Arthritis research & therapy (01.01.2010)
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Interferon-γ Signaling Inhibition Ameliorates Angiotensin II–Induced Cardiac Damage
Markó, Lajos, Kvakan, Heda, Park, Joon-Keun, Qadri, Fatimunnisa, Spallek, Bastian, Binger, Katrina J, Bowman, Edward P, Kleinewietfeld, Markus, Fokuhl, Verena, Dechend, Ralf, Müller, Dominik N
Published in Hypertension (Dallas, Tex. 1979) (01.12.2012)
Published in Hypertension (Dallas, Tex. 1979) (01.12.2012)
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