The history of Toll-like receptors - redefining innate immunity
O'Neill, Luke A J, Golenbock, Douglas, Bowie, Andrew G
Published in Nature reviews. Immunology (01.06.2013)
Published in Nature reviews. Immunology (01.06.2013)
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Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor
Jin, Tengchuan, Perry, Andrew, Jiang, Jiansheng, Smith, Patrick, Curry, James A., Unterholzner, Leonie, Jiang, Zhaozhao, Horvath, Gabor, Rathinam, Vijay A., Johnstone, Ricky W., Hornung, Veit, Latz, Eicke, Bowie, Andrew G., Fitzgerald, Katherine A., Xiao, T. Sam
Published in Immunity (Cambridge, Mass.) (20.04.2012)
Published in Immunity (Cambridge, Mass.) (20.04.2012)
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The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons
Carroll, Elizabeth. C., Jin, Lei, Mori, Andres, Muñoz-Wolf, Natalia, Oleszycka, Ewa, Moran, Hannah B.T., Mansouri, Samira, McEntee, Craig P., Lambe, Eimear, Agger, Else Marie, Andersen, Peter, Cunningham, Colm, Hertzog, Paul, Fitzgerald, Katherine A., Bowie, Andrew G., Lavelle, Ed C.
Published in Immunity (Cambridge, Mass.) (15.03.2016)
Published in Immunity (Cambridge, Mass.) (15.03.2016)
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IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes
Almine, Jessica F, O'Hare, Craig A J, Dunphy, Gillian, Haga, Ismar R, Naik, Rangeetha J, Atrih, Abdelmadjid, Connolly, Dympna J, Taylor, Jordan, Kelsall, Ian R, Bowie, Andrew G, Beard, Philippa M, Unterholzner, Leonie
Published in Nature communications (13.02.2017)
Published in Nature communications (13.02.2017)
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IFI16 is an innate immune sensor for intracellular DNA
Bowie, Andrew G, Unterholzner, Leonie, Keating, Sinead E, Baran, Marcin, Horan, Kristy A, Jensen, Søren B, Sharma, Shruti, Sirois, Cherilyn M, Jin, Tengchuan, Latz, Eicke, Xiao, T Sam, Fitzgerald, Katherine A, Paludan, Søren R
Published in Nature immunology (01.11.2010)
Published in Nature immunology (01.11.2010)
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Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors
Sisquella, Xavier, Ofir-Birin, Yifat, Pimentel, Matthew A, Cheng, Lesley, Abou Karam, Paula, Sampaio, Natália G, Penington, Jocelyn Sietsma, Connolly, Dympna, Giladi, Tal, Scicluna, Benjamin J, Sharples, Robyn A, Waltmann, Andreea, Avni, Dror, Schwartz, Eli, Schofield, Louis, Porat, Ziv, Hansen, Diana S, Papenfuss, Anthony T, Eriksson, Emily M, Gerlic, Motti, Hill, Andrew F, Bowie, Andrew G, Regev-Rudzki, Neta
Published in Nature communications (07.12.2017)
Published in Nature communications (07.12.2017)
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Myeloid cell nuclear differentiation antigen controls the pathogen-stimulated type I interferon cascade in human monocytes by transcriptional regulation of IRF7
Gu, Lili, Casserly, David, Brady, Gareth, Carpenter, Susan, Bracken, Adrian P, Fitzgerald, Katherine A, Unterholzner, Leonie, Bowie, Andrew G
Published in Nature communications (10.01.2022)
Published in Nature communications (10.01.2022)
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Neuronal Toll-like receptor 4 signaling induces brain endothelial activation and neutrophil transmigration in vitro
Leow-Dyke, Sophie, Allen, Charlotte, Denes, Adam, Nilsson, Olov, Maysami, Samaneh, Bowie, Andrew G, Rothwell, Nancy J, Pinteaux, Emmanuel
Published in Journal of neuroinflammation (03.10.2012)
Published in Journal of neuroinflammation (03.10.2012)
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Reactive Centre Loop Mutagenesis of SerpinB3 to Target TMPRSS2 and Furin: Inhibition of SARS-CoV-2 Cell Entry and Replication
Singh, Saravjeet, O’Reilly, Sophie, Gewaid, Hossam, Bowie, Andrew G., Gautier, Virginie, Worrall, D. Margaret
Published in International journal of molecular sciences (19.10.2022)
Published in International journal of molecular sciences (19.10.2022)
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TRAM is required for TLR2 endosomal signaling to type I IFN induction
Stack, Julianne, Doyle, Sarah L, Connolly, Dympna J, Reinert, Line S, O'Keeffe, Kate M, McLoughlin, Rachel M, Paludan, Søren R, Bowie, Andrew G
Published in The Journal of immunology (1950) (15.12.2014)
Published in The Journal of immunology (1950) (15.12.2014)
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Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors
Horan, Kristy A, Hansen, Kathrine, Jakobsen, Martin R, Holm, Christian K, Søby, Stine, Unterholzner, Leonie, Thompson, Mikayla, West, John A, Iversen, Marie B, Rasmussen, Simon B, Ellermann-Eriksen, Svend, Kurt-Jones, Evelyn, Landolfo, Santo, Damania, Blossom, Melchjorsen, Jesper, Bowie, Andrew G, Fitzgerald, Katherine A, Paludan, Søren R
Published in The Journal of immunology (1950) (01.03.2013)
Published in The Journal of immunology (1950) (01.03.2013)
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SARM1 Ablation Is Protective and Preserves Spatial Vision in an In Vivo Mouse Model of Retinal Ganglion Cell Degeneration
Finnegan, Laura K, Chadderton, Naomi, Kenna, Paul F, Palfi, Arpad, Carty, Michael, Bowie, Andrew G, Millington-Ward, Sophia, Farrar, G Jane
Published in International journal of molecular sciences (30.01.2022)
Published in International journal of molecular sciences (30.01.2022)
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