Hepatobiliary circulation and dominant urinary excretion of homogentisic acid in a mouse model of alkaptonuria
Norman, B. P., Sutherland, H., Wilson, P. J. M., Rutland, D. A., Milan, A. M., Hughes, A. T., Davison, A. S., Khedr, M., Jarvis, J. C., Gallagher, J. A., Bou‐Gharios, G., Ranganath, L. R.
Published in Journal of inherited metabolic disease (01.07.2024)
Published in Journal of inherited metabolic disease (01.07.2024)
Get full text
Journal Article
Determinants of tyrosinaemia during nitisinone therapy in alkaptonuria
Ranganath, L. R., Milan, A. M., Hughes, A. T., Davison, A. S., M, Khedr, Norman, B. P., Bou-Gharios, G., Gallagher, J. A., Imrich, R., Arnoux, J. B., Rudebeck, M., Olsson, B.
Published in Scientific reports (27.09.2022)
Published in Scientific reports (27.09.2022)
Get full text
Journal Article
Joint replacement risk is markedly increased in alkaptonuria (AKU) in those with prior arthroplasty
Ranganath, L.R., Khedr, M., Norman, B.P., Hughes, J.H., Imrich, R., Arnoux, J.B., Olsson, B., Rudebeck, M., Gallagher, J.A., Bou-Gharios, G.
Published in Molecular genetics and metabolism reports (01.09.2024)
Published in Molecular genetics and metabolism reports (01.09.2024)
Get full text
Journal Article
Characterization of changes in the tyrosine pathway by 24-h profiling during nitisinone treatment in alkaptonuria
Ranganath, L.R., Milan, A.M., Hughes, A.T., Davison, A.S., Khedr, M., Norman, B.P., Bou-Gharios, G., Gallagher, J.A., Gornall, M., Jackson, R., Imrich, R., Rovensky, J., Rudebeck, M., Olsson, B.
Published in Molecular genetics and metabolism reports (01.03.2022)
Published in Molecular genetics and metabolism reports (01.03.2022)
Get full text
Journal Article
Injected human umbilical cord-derived mesenchymal stromal cells do not appear to elicit an inflammatory response in a murine model of osteoarthritis
Perry, J., McCarthy, H.S., Bou-Gharios, G., van 't Hof, R., Milner, P.I., Mennan, C., Roberts, S.
Published in Osteoarthritis and cartilage open (01.06.2020)
Published in Osteoarthritis and cartilage open (01.06.2020)
Get full text
Journal Article
Transplantation of human fetal mesenchymal stem cells improves glomerulopathy in a collagen type Iα2-deficient mouse
Guillot, PV, Cook, HT, Pusey, CD, Fisk, NM, Harten, S, Moss, J, Shore, I, Bou-Gharios, G
Published in The Journal of pathology (01.04.2008)
Published in The Journal of pathology (01.04.2008)
Get full text
Journal Article
Temporal adaptations in the phenylalanine/tyrosine pathway and related factors during nitisinone-induced tyrosinaemia in alkaptonuria
Ranganath, L R, Hughes, A T, Davison, A S, Khedr, M, Olsson, B, Rudebeck, M, Imrich, R, Norman, B P, Bou-Gharios, G, Gallagher, J A, Milan, A M
Published in Molecular genetics and metabolism (01.06.2022)
Published in Molecular genetics and metabolism (01.06.2022)
Get full text
Journal Article
In vivo imaging of MMP-13 activity in the murine destabilised medial meniscus surgical model of osteoarthritis
Lim, N.H, Meinjohanns, E, Meldal, M, Bou-Gharios, G, Nagase, H
Published in Osteoarthritis and cartilage (01.06.2014)
Published in Osteoarthritis and cartilage (01.06.2014)
Get full text
Journal Article
Assessing the effect of nitisinone induced hypertyrosinaemia on monoamine neurotransmitters in brain tissue from a murine model of alkaptonuria using mass spectrometry imaging
Davison, A. S., Strittmatter, N., Sutherland, H., Hughes, A. T., Hughes, J., Bou-Gharios, G., Milan, A. M., Goodwin, R. J. A., Ranganath, L. R., Gallagher, J. A.
Published in Metabolomics (01.05.2019)
Published in Metabolomics (01.05.2019)
Get full text
Journal Article
A cluster of regulatory elements that drives the aggrecan gene expression in chondrocytes
Li, I.M, Liu, K, Neal, A, Clegg, P.D, De Val, S, Bou-Gharios, G
Published in Osteoarthritis and cartilage (01.04.2016)
Published in Osteoarthritis and cartilage (01.04.2016)
Get full text
Journal Article
Persistent global inflammation caused by the loss of SIRT1 protects against experimental osteoarthritis
Sacitharan, P, Zarebska, J.M, Stott, B, Parisi, I, Curtinha, M, Bou-Gharios, G, Edwards, J.R, Vincent, T
Published in Osteoarthritis and cartilage (01.04.2017)
Published in Osteoarthritis and cartilage (01.04.2017)
Get full text
Journal Article
The tissue specific role of SirT1 in joint inflammation and anabolic cartilage gene expression
Sacitharan, P.K, Zarebska, J, Chanalaris, A, Bou Gharios, G, J, E, Vincent, T.L
Published in Osteoarthritis and cartilage (01.04.2015)
Published in Osteoarthritis and cartilage (01.04.2015)
Get full text
Journal Article
Loss of SIRT1 impairs autophagy in chondrocytes and is associated with accelerated cartilage aging and experimental osteoarthritis
Sacitharan, P.K, Zarebska, J, Nechyporuk-Zloy, V, Stott, B, Curtinha, M, Parisi, I, Bou Gharios, G, Edwards, J, Vincent, T.L
Published in Osteoarthritis and cartilage (01.04.2016)
Published in Osteoarthritis and cartilage (01.04.2016)
Get full text
Journal Article
Connective tissue growth factor deficiency in adult articular cartilage promotes cartilage degeneration at early timepoints in mouse posttraumatic osteoarthritis
Poulet, B, Milner, P, Kanakis, I, Carter, A, Abraham, D, Leask, A, Hof, R. Van't, Bou-Gharios, G
Published in Osteoarthritis and cartilage (01.04.2016)
Published in Osteoarthritis and cartilage (01.04.2016)
Get full text
Journal Article
The role of microRNAs in osteoarthritis and ageing-related functional decline in joint tissue homeostasis
House, L, Bou-Gharios, G, Peffers, M, Milner, P, Clegg, P.D, Young, D.A, Whysall, K.A
Published in Osteoarthritis and cartilage (01.04.2016)
Published in Osteoarthritis and cartilage (01.04.2016)
Get full text
Journal Article
Correction to: Assessing the effect of nitisinone induced hypertyrosinaemia on monoamine neurotransmitters in brain tissue from a murine model of alkaptonuria using mass spectrometry imaging
Davison, Andrew S., Strittmatter, N., Sutherland, H., Hughes, A. T., Hughes, J., Bou-Gharios, G., Milan, A. M., Goodwin, R. J. A., Ranganath, L. R., Gallagher, J. A.
Published in Metabolomics (18.05.2019)
Published in Metabolomics (18.05.2019)
Get full text
Journal Article