Vildagliptin alleviates liver fibrosis in NASH diabetic rats via modulation of insulin resistance, oxidative stress, and inflammatory cascades
Hendawy, Ahmed S., El-Lakkany, Naglaa M., Mantawy, Eman M., Hammam, Olfat A., Botros, Sanaa S., El-Demerdash, Ebtehal
Published in Life sciences (1973) (01.09.2022)
Published in Life sciences (1973) (01.09.2022)
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Gut microbiota modulation as a promising therapy with metformin in rats with non-alcoholic steatohepatitis: Role of LPS/TLR4 and autophagy pathways
Ahmed, Lamiaa A., Salem, Maha B., Seif el-Din, Sayed H., El-Lakkany, Naglaa M., Ahmed, Hend O., Nasr, Sami M., Hammam, Olfat A., Botros, Sanaa S., Saleh, Samira
Published in European journal of pharmacology (15.11.2020)
Published in European journal of pharmacology (15.11.2020)
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Cloning and functional complementation of ten Schistosoma mansoni phosphodiesterases expressed in the mammalian host stages
Munday, Jane C, Kunz, Stefan, Kalejaiye, Titilola D, Siderius, Marco, Schroeder, Susanne, Paape, Daniel, Alghamdi, Ali H, Abbasi, Zainab, Huang, Sheng Xiang, Donachie, Anne-Marie, William, Samia, Sabra, Abdel Nasser, Sterk, Geert Jan, Botros, Sanaa S, Brown, David G, Hoffman, Charles S, Leurs, Rob, de Koning, Harry P
Published in PLoS neglected tropical diseases (01.07.2020)
Published in PLoS neglected tropical diseases (01.07.2020)
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Journal Article
To Target or Not to Target Schistosoma mansoni Cyclic Nucleotide Phosphodiesterase 4A?
Zheng, Yang, Schroeder, Susanne, Kanev, Georgi K, Botros, Sanaa S, William, Samia, Sabra, Abdel-Nasser A, Maes, Louis, Caljon, Guy, Gil, Carmen, Martinez, Ana, Salado, Irene G, Augustyns, Koen, Edink, Ewald, Sijm, Maarten, de Heuvel, Erik, de Esch, Iwan J P, van der Meer, Tiffany, Siderius, Marco, Sterk, Geert Jan, Brown, David, Leurs, Rob
Published in International journal of molecular sciences (06.04.2023)
Published in International journal of molecular sciences (06.04.2023)
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Chemical Profiling of Polyphenolics in Eucalyptus globulus and Evaluation of Its Hepato–Renal Protective Potential Against Cyclophosphamide Induced Toxicity in Mice
Ghareeb, Mosad A., Sobeh, Mansour, El-Maadawy, Walaa H., Mohammed, Hala Sh, Khalil, Heba, Botros, Sanaa, Wink, Michael
Published in Antioxidants (19.09.2019)
Published in Antioxidants (19.09.2019)
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Journal Article
A novel praziquantel solid lipid nanoparticle formulation shows enhanced bioavailability and antischistosomal efficacy against murine S. mansoni infection
Radwan, Amr, El-Lakkany, Naglaa M, William, Samia, El-Feky, Gina S, Al-Shorbagy, Muhammad Y, Saleh, Samira, Botros, Sanaa
Published in Parasites & vectors (17.06.2019)
Published in Parasites & vectors (17.06.2019)
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Journal Article
Antifibrotic effects of gallic acid on hepatic stellate cells: In vitro and in vivo mechanistic study
El-Lakkany, Naglaa M., El-Maadawy, Walaa H., Seif el-Din, Sayed H., Saleh, Samira, Safar, Marwa M., Ezzat, Shahira M., Mohamed, Salwa H., Botros, Sanaa S., Demerdash, Zeinab, Hammam, Olfat A.
Published in Journal of Traditional and Complementary Medicine (01.01.2019)
Published in Journal of Traditional and Complementary Medicine (01.01.2019)
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Journal Article
The phosphodiesterase-4 inhibitor roflumilast impacts Schistosoma mansoni ovipositing in vitro but displays only modest antischistosomal activity in vivo
Botros, Sanaa S., El-Lakkany, Naglaa M., Seif el-Din, Sayed H., William, Samia, Sabra, Abdel-Nasser, Hammam, Olfat A., de Koning, Harry P.
Published in Experimental parasitology (01.01.2020)
Published in Experimental parasitology (01.01.2020)
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Journal Article
Metabolic profile and hepatoprotective activity of the anthocyanin-rich extract of Hibiscus sabdariffa calyces
Ezzat, Shahira M., Salama, Maha M., Seif el-Din, Sayed H., Saleh, Samira, El-Lakkany, Naglaa M., Hammam, Olfat A., Salem, Maha B., Botros, Sanaa S.
Published in Pharmaceutical biology (01.12.2016)
Published in Pharmaceutical biology (01.12.2016)
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Journal Article
Deciphering the enzymatic target of a new family of antischistosomal agents bearing a quinazoline scaffold using complementary computational tools
Sebastian-Perez, Victor, García-Rubia, Alfonso, Seif el-Din, Sayed H., Sabra, Abdel-Nasser A., El-Lakkany, Naglaa M., William, Samia, Blundell, Tom L., Maes, Louis, Martinez, Ana, Campillo, Nuria E., Botros, Sanaa S., Gil, Carmen
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2020)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2020)
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Journal Article
Praziquantel in a clay nanoformulation shows more bioavailability and higher efficacy against murine Schistosoma mansoni infection
El-Feky, Gina S, Mohamed, Wael S, Nasr, Hanaa E, El-Lakkany, Naglaa M, Seif El-Din, Sayed H, Botros, Sanaa S
Published in Antimicrobial agents and chemotherapy (01.06.2015)
Published in Antimicrobial agents and chemotherapy (01.06.2015)
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Journal Article
Praziquantel efficacy in mice infected with PZQ non-susceptible S. mansoni isolate treated with artemether: parasitological, biochemical and immunohistochemical assessment
Botros, Sanaa S, Hammam, Olfat, Mahmoud, Madiha, Bergquist, Robert
Published in APMIS : acta pathologica, microbiologica et immunologica Scandinavica (01.09.2010)
Published in APMIS : acta pathologica, microbiologica et immunologica Scandinavica (01.09.2010)
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Journal Article
Screening of a PDE-focused library identifies imidazoles with in vitro and in vivo antischistosomal activity
Botros, Sanaa S., William, Samia, Sabra, Abdel-Nasser A., El-Lakkany, Naglaa M., Seif el-Din, Sayed H., García-Rubia, Alfonso, Sebastián-Pérez, Victor, Blaazer, Antoni R., de Heuvel, Erik, Sijm, Maarten, Zheng, Yang, Salado, Irene G., Munday, Jane C., Maes, Louis, de Esch, Iwan J.P., Sterk, Geert J., Augustyns, Koen, Leurs, Rob, Gil, Carmen, De Koning, Harry P.
Published in International journal for parasitology -- drugs and drug resistance (01.04.2019)
Published in International journal for parasitology -- drugs and drug resistance (01.04.2019)
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Journal Article
Bioavailability of paracetamol with/without caffeine in Egyptian patients with hepatitis C virus
El-Lakkany, Naglaa M., Hendawy, Ahmed S., Seif el-Din, Sayed H., Ashour, Ahmed A., Atta, Raafat, Abdel-Aziz, Abdel-Aziz H., Mansour, Ahmed M., Botros, Sanaa S.
Published in European journal of clinical pharmacology (01.05.2016)
Published in European journal of clinical pharmacology (01.05.2016)
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Journal Article
Resveratrol mitigates hepatic injury in rats by regulating oxidative stress, nuclear factor-kappa B, and apoptosis
Seif el.Din, Sayed, El-Lakkany, Naglaa, Salem, Maha, Hammam, Olfat, Saleh, Samira, Botros, Sanaa
Published in Journal of advanced pharmaceutical technology and research (01.07.2016)
Published in Journal of advanced pharmaceutical technology and research (01.07.2016)
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Journal Article
Antischistosomal Activity of Hexadecyloxypropyl Cyclic 9-(S)-[3-Hydroxy-2-(Phosphonomethoxy)Propyl]Adenine and Other Alkoxyalkyl Esters of Acyclic Nucleoside Phosphonates Assessed by Schistosome Worm Killing In Vitro
BOTROS, Sanaa S, WILLIAM, Samia, BEADLE, James R, VALIAEVA, Nadejda, HOSTETLER, Karl Y
Published in Antimicrobial Agents and Chemotherapy (01.12.2009)
Published in Antimicrobial Agents and Chemotherapy (01.12.2009)
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Journal Article
Efficacy and safety of artemether in the treatment of chronic fascioliasis in Egypt: exploratory phase-2 trials
Keiser, Jennifer, Sayed, Hanan, el-Ghanam, Maged, Sabry, Hoda, Anani, Saad, el-Wakeel, Aly, Hatz, Christoph, Utzinger, Jürg, el-Din, Sayed Seif, el-Maadawy, Walaa, Botros, Sanaa
Published in PLoS neglected tropical diseases (01.09.2011)
Published in PLoS neglected tropical diseases (01.09.2011)
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Journal Article
Potential effect of the medicinal plants Calotropis procera. Ficus elastica and Zingiber officinale against Schistosoma mansoni in mice
Seif el-Din, Sayed H., El-Lakkany, Naglaa M., Mohamed, Mona A., Hamed, Manal M., Sterner, Olov, Botros, Sanaa S.
Published in Pharmaceutical biology (01.02.2014)
Published in Pharmaceutical biology (01.02.2014)
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