Identification of a Benzimidazolecarboxylic Acid Derivative (BAY 1316957) as a Potent and Selective Human Prostaglandin E2 Receptor Subtype 4 (hEP4-R) Antagonist for the Treatment of Endometriosis
Bäurle, Stefan, Nagel, Jens, Peters, Olaf, Bräuer, Nico, ter Laak, Antonius, Preusse, Cornelia, Rottmann, Antje, Heldmann, Dieter, Bothe, Ulrich, Blume, Thorsten, Zorn, Ludwig, Walter, Daryl, Zollner, Thomas M, Steinmeyer, Andreas, Langer, Gernot
Published in Journal of medicinal chemistry (14.03.2019)
Published in Journal of medicinal chemistry (14.03.2019)
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ortho-Carboranyl Glycosides for the Treatment of Cancer by Boron Neutron Capture Therapy
Tietze, Lutz F, Bothe, Ulrich, Griesbach, Ulrich, Nakaichi, Munekazu, Hasegawa, Toshinari, Nakamura, Hiroyuki, Yamamoto, Yoshinori
Published in Bioorganic & medicinal chemistry (01.07.2001)
Published in Bioorganic & medicinal chemistry (01.07.2001)
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Carboranyl Bisglycosides for the Treatment of Cancer by Boron Neutron Capture Therapy
Tietze, Lutz F., Bothe, Ulrich, Griesbach, Ulrich, Nakaichi, Munekazu, Hasegawa, Toshinari, Nakamura, Hiroyuki, Yamamoto, Yoshinori
Published in Chembiochem : a European journal of chemical biology (04.05.2001)
Published in Chembiochem : a European journal of chemical biology (04.05.2001)
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Preparation of a New Carboranyl Lactoside for the Treatment of Cancer by Boron Neutron Capture Therapy: Synthesis and Toxicity of Fluoro Carboranyl Glycosides for in vivo19F-NMR Spectroscopy
Tietze, Lutz F., Bothe, Ulrich, Schuberth, Ingrid
Published in Chemistry : a European journal (03.03.2000)
Published in Chemistry : a European journal (03.03.2000)
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Discovery of BAY-390, a Selective CNS Penetrant Chemical Probe as Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonist
Mesch, Stefanie, Walter, Daryl, Laux-Biehlmann, Alexis, Basting, Daniel, Flanagan, Stuart, Miyatake Ondozabal, Hideki, Bäurle, Stefan, Pearson, Christopher, Jenkins, James, Elves, Philip, Hess, Stephen, Coelho, Anne-Marie, Rotgeri, Andrea, Bothe, Ulrich, Nawaz, Schanila, Zollner, Thomas M., Steinmeyer, Andreas
Published in Journal of medicinal chemistry (26.01.2023)
Published in Journal of medicinal chemistry (26.01.2023)
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Discovery of IRAK4 Inhibitors BAY1834845 (Zabedosertib) and BAY1830839
Bothe, Ulrich, Günther, Judith, Nubbemeyer, Reinhard, Siebeneicher, Holger, Ring, Sven, Bömer, Ulf, Peters, Michaele, Rausch, Alexandra, Denner, Karsten, Himmel, Herbert, Sutter, Andreas, Terebesi, Ildiko, Lange, Martin, Wengner, Antje M., Guimond, Nicolas, Thaler, Tobias, Platzek, Johannes, Eberspächer, Uwe, Schäfer, Martina, Steuber, Holger, Zollner, Thomas M., Steinmeyer, Andreas, Schmidt, Nicole
Published in Journal of medicinal chemistry (25.01.2024)
Published in Journal of medicinal chemistry (25.01.2024)
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Discovery and In Vitro Characterization of BAY 2686013, an Allosteric Small Molecule Antagonist of the Human Pituitary Adenylate Cyclase-Activating Polypeptide Receptor
Langer, Gernot, Scott, John, Lind, Christoffer, Otto, Christiane, Bothe, Ulrich, Laux-Biehlmann, Alexis, Müller, Jörg, le Roy, Beau, Irlbacher, Horst, Nowak-Reppel, Katrin, Schlüter, Anne, Davenport, Adam J, Slack, Mark, Bäurle, Stefan
Published in Molecular pharmacology (01.09.2023)
Published in Molecular pharmacology (01.09.2023)
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Discovery of selective urokinase plasminogen activator (uPA) inhibitors as a potential treatment for multiple sclerosis
Islam, Imadul, Yuan, Shendong, West, Christopher W., Adler, Marc, Bothe, Ulrich, Bryant, Judi, Chang, Zheng, Chu, Kieu, Emayan, Kumar, Gualtieri, Giovanna, Ho, Elena, Light, David, Mallari, Cornell, Morser, John, Phillips, Gary, Schaefer, Caralee, Sukovich, Drew, Whitlow, Marc, Chen, Deborah, Buckman, Brad O.
Published in Bioorganic & medicinal chemistry letters (01.11.2018)
Published in Bioorganic & medicinal chemistry letters (01.11.2018)
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Abstract 1887: Preclinical evaluation of a novel interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor in combination with PI3K inhibitor copanlisib or BTK inhibitors in ABC-DLBCL
Lange, Martin, Wengner, Antje Margret, Bothe, Ulrich, Boemer, Ulf, Nubbemeyer, Reinhard, Siebeneicher, Holger, Steuber, Holger, Guenther, Judith, Potze, Lisette, Schmidt, Nicole, Politz, Oliver, Doecke, Wolf-Dietrich, Lagkadinou, Eleni, Zollner, Thomas M., Nussbaum, Franz von, Mumberg, Dominik, Steinmeyer, Andreas, Brands, Michael, Ziegelbauer, Karl
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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BADER BENJAMIN, GUENTHER JUDITH, ZORN LUDWIG, MEIER ROBIN MICHAEL, GUTCHER ILONA, BAUMANN DANIEL, BUCHMANN BERND, SCHMEES NORBERT, GORJANACZ MATYAS, HERBERT SIMON ANTHONY, STOECKIGT DETLEF, PLATTEN MICHAEL, LEFRANC JULIEN, KOBER CHRISTINA, BOTHE ULRICH, BOEHME STEPHAN, ROESE LARS
Year of Publication 13.04.2022
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Year of Publication 13.04.2022
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자가면역 질환의 치료 및 예방을 위한 2-치환된 인다졸의 용도
KRAETZSCHMAR JOERN, JODL STEFAN JOACHIM, SCHMIDT NICOLE, BOTHE ULRICH, RAUSCH ALEXANDRA
Year of Publication 13.02.2019
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Year of Publication 13.02.2019
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동물에서의 알레르기성 및/또는 염증성 질환의 치료 및 예방에 유용한 치환된 인다졸
BOEMER ULF, BEDDIES GERALD, MOTTIER MARIA DE LOURDES, SCHMIDT NICOLE, NUBBEMEYER REINHARD, BOTHE ULRICH, FOSTER ADRIAN
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Year of Publication 13.02.2019
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Year of Publication 24.07.2017
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Year of Publication 24.07.2017
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NOVEL CARBOXAMIDES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS COMPRISING THEM, AND USE THEREOF FOR PRODUCING MEDICAMENTS
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Year of Publication 09.08.2016
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Year of Publication 09.08.2016
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6,7-DIHYDRO-5H-BENZO[7]ANNULENE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS THAT CONTAIN SAID 6,7-DIHYDRO-5H-BENZO[7]ANNULENE DERIVATIVES, AND USE THEREOF TO PRODUCE DRUGS
MOELLER CARSTEN, BOHLMANN ROLF, WINTERMANTEL TIM, ZORN LUDWIG, NUBBEMEYER REINHARD, BOTHE ULRICH, TER LAAK ANTONIUS, WORTMANN LARS
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Year of Publication 04.09.2014
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ESTRA-1,3,5(10),16-TETRAENE-3-CARBOXAMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, PHARMACEUTICAL PREPARATIONS COMPRISING THEM, AND USE THEREOF FOR PRODUCTION OF MEDICAMENTS
ROTGERI ANDREA, GASHAW ISABELLA, HARTUNG INGO, BARAK NAOMI, MARQUARDT TOBIAS, BUSEMANN MATTHIAS, BOTHE ULRICH, FISCHER OLIVER MARTIN
Year of Publication 09.06.2014
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Year of Publication 09.06.2014
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6,7-DIHYDRO-5H-BENZO[7]ANNULENE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, PHARMACEUTICAL PREPARATIONS COMPRISING THEM, AND THE USE THEREOF FOR PRODUCTION OF MEDICAMENTS
MOELLER CARSTEN, BIERER DONALD, BOHLMANN ROLF, WINTERMANTEL TIM, ZORN LUDWIG, KOSEMUND DIRK, NUBBEMEYER REINHARD, BOTHE ULRICH, TER LAAK ANTONIUS, WORTMANN LARS
Year of Publication 09.08.2013
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Year of Publication 09.08.2013
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