Intrahepatic and Peripheral CXCL10 Expression in Hepatitis C Virus-Infected Patients Treated With Telaprevir, Pegylated Interferon, and Ribavirin
Zeremski, Marija, Dimova, Rositsa B., Benjamin, Samantha, Penney, Marina S., Botfield, Martyn C., Talal, Andrew H.
Published in The Journal of infectious diseases (01.06.2015)
Published in The Journal of infectious diseases (01.06.2015)
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Journal Article
Telaprevir‐based treatment effects on hepatitis C virus in liver and blood
Talal, Andrew H., Dimova, Rositsa B., Zhang, Eileen Z., Jiang, Min, Penney, Marina S., Sullivan, James C., Botfield, Martyn C., Chakilam, Ananthsrinivas, Sawant, Rishikesh, Cervini, Christine M., Zeremski, Marija, Jacobson, Ira M., Kwong, Ann D.
Published in Hepatology (Baltimore, Md.) (01.12.2014)
Published in Hepatology (Baltimore, Md.) (01.12.2014)
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Hyperpolarized helium-3 magnetic resonance lung imaging of non-sedated infants and young children: a proof-of-concept study
Altes, Talissa A, Meyer, Craig H, Mata, Jaime F, Froh, Deborah K, Paget-Brown, Alix, Gerald Teague, W, Fain, Sean B, de Lange, Eduard E, Ruppert, Kai, Botfield, Martyn C, Johnson, Mac A, Mugler, John P
Published in Clinical imaging (01.09.2017)
Published in Clinical imaging (01.09.2017)
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Journal Article
Tandem SH2 Domains Confer High Specificity in Tyrosine Kinase Signaling
Ottinger, Elizabeth A., Botfield, Martyn C., Shoelson, Steven E.
Published in The Journal of biological chemistry (09.01.1998)
Published in The Journal of biological chemistry (09.01.1998)
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Journal Article
TELAPREVIR-BASED REGIMENS SUBSTANTIALLY IMPROVED SVR RATES ACROSS ALL IL28B GENOTYPES IN THE ADVANCE TRIAL
Jacobson, Ira M, Catlett, Ian M, Marcellin, Patrick, Bzowej, Natalie H, Muir, Andrew J, Adda, Nathalie, Seepersaud, Shelia, Ramachandran, Ravi, Sussky, Katherine, Bengtsson, Leif, George, Shelley, Kauffman, Robert S, Botfield, Martyn C
Published in Gastroenterology (New York, N.Y. 1943) (2011)
Published in Gastroenterology (New York, N.Y. 1943) (2011)
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Journal Article
Similar SVR Rates in IL28B CC, CT or TT Prior Relapser, Partial- or Null-Responder Patients Treated With Telaprevir/Peginterferon/Ribavirin: Retrospective Analysis of the Realize Study
Younossi, Zobair M, Aerssens, Jeroen, Pol, Stanislas, Pockros, Paul, Lawitz, Eric J, Zeuzem, Stefan, Andreone, Pietro, Roberts, Stuart K, Foster, Graham, Focaccia, Roberto, Horban, Andrzej, van Heeswijk, Rolf, De Meyer, Sandra, Luo, Don, Botfield, Martyn C, Beumont-Mauviel, Maria, Picchio, Gaston
Published in Gastroenterology (New York, N.Y. 1943) (2011)
Published in Gastroenterology (New York, N.Y. 1943) (2011)
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Journal Article
Telaprevir‐based treatment effects on hepatitis C virus in liver and blood
Talal, Andrew H., Dimova, Rositsa B., Zhang, Eileen Z., Jiang, Min, Penney, Marina S., Sullivan, James C., Botfield, Martyn C., Chakilam, Ananthsrinivas, Sawant, Rishikesh, Cervini, Christine M., Zeremski, Marija, Jacobson, Ira M., Kwong, Ann D.
Published in Hepatology (Baltimore, Md.) (01.12.2014)
Published in Hepatology (Baltimore, Md.) (01.12.2014)
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Journal Article
Phage Display Selection of Ligand Residues Important for Src Homology 3 Domain Binding Specificity
Rickles, Richard J., Botfield, Martyn C., Zhou, Xiao-Mai, Henry, Pamela A., Brugge, Joan S.
Published in Proceedings of the National Academy of Sciences - PNAS (21.11.1995)
Published in Proceedings of the National Academy of Sciences - PNAS (21.11.1995)
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Journal Article
Discovery of Potent and Selective SH2 Inhibitors of the Tyrosine Kinase ZAP-70
Vu, Chi B, Corpuz, Evelyn G, Merry, Taylor J, Pradeepan, Selvaluxmi G, Bartlett, Catherine, Bohacek, Regine S, Botfield, Martyn C, Eyermann, Charles J, Lynch, Berkley A, MacNeil, Ian A, Ram, Mary K, van Schravendijk, Marie Rose, Violette, Shelia, Sawyer, Tomi K
Published in Journal of medicinal chemistry (07.10.1999)
Published in Journal of medicinal chemistry (07.10.1999)
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Journal Article
PROCESS FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
ROEPER STEFANIE, RYAN MICHAEL P, BOTFIELD MARTYN C, TRUDEAU MARTIN, KRUEGER BRIAN R, YAP DAHRIKA MILFRED LAO, ZLOKARNIK GREGOR, VAN GOOR FREDERICK F, DEMATTEI JOHN, LOOKER ADAM R, GROOTENHUIS PETER D.J, NEUBERT LANGILLE BOBBIANNA
Year of Publication 27.04.2018
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Year of Publication 27.04.2018
Patent
PROCESS FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
ROEPER STEFANIE, RYAN MICHAEL P, BOTFIELD MARTYN C, TRUDEAU MARTIN, KRUEGER BRIAN R, YAP DAHRIKA MILFRED LAO, ZLOKARNIK GREGOR, VAN GOOR FREDERICK F, DEMATTEI JOHN, LOOKER ADAM R, GROOTENHUIS PETER D.J, NEUBERT LANGILLE BOBBIANNA
Year of Publication 19.04.2017
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Year of Publication 19.04.2017
Patent
An efficient synthesis of a 4′-phosphonodifluoromethyl-3′-formyl-phenylalanine containing Src SH2 ligand
Shakespeare, William C., Bohacek, Regine S., Narula, Surinder S., Azimioara, Mihai D., Yuan, Ruth W., Dalgarno, David C., Madden, Laura, Botfield, Martyn C., Holt, Dennis A.
Published in Bioorganic & medicinal chemistry letters (01.11.1999)
Published in Bioorganic & medicinal chemistry letters (01.11.1999)
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Journal Article
The construction of a cysteine-less melibiose carrier from E. coli
Weissborn, Audrey C, Botfield, Martyn C, Kuroda, Masayuki, Tsuchiya, Tomofusa, Wilson, T.Hastings
Published in Biochimica et biophysica acta (23.10.1997)
Published in Biochimica et biophysica acta (23.10.1997)
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Journal Article
Selective Inhibition of Src SH2 by a Novel Thiol-Targeting Tricarbonyl-Modified Inhibitor and Mechanistic Analysis by 1H/ 13C NMR Spectroscopy
Sundaramoorthi, Raji, Siedem, Chris, Vu, Chi B, Dalgarno, David C, Laird, Ellen C, Botfield, Martyn C, Combs, Amanda B, Adams, Susan E, Yuan, Ruth W, Weigele, Manfred, Narula, Surinder S
Published in Bioorganic & medicinal chemistry letters (01.07.2001)
Published in Bioorganic & medicinal chemistry letters (01.07.2001)
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Journal Article
PROCESS FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
ROEPER STEFANIE, RYAN MICHAEL P, BOTFIELD MARTYN C, TRUDEAU MARTIN, KRUEGER BRIAN R, YAP DAHRIKA MILFRED LAO, ZLOKARNIK GREGOR, VAN GOOR FREDERICK F, DEMATTEI JOHN, LOOKER ADAM R, GROOTENHUIS PETER D.J, NEUBERT LANGILLE BOBBIANNA
Year of Publication 05.12.2011
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Year of Publication 05.12.2011
Patent