Lack of Widespread BBB Disruption in Alzheimer’s Disease Models: Focus on Therapeutic Antibodies
Bien-Ly, Nga, Boswell, C. Andrew, Jeet, Surinder, Beach, Thomas G., Hoyte, Kwame, Luk, Wilman, Shihadeh, Vera, Ulufatu, Sheila, Foreman, Oded, Lu, Yanmei, DeVoss, Jason, van der Brug, Marcel, Watts, Ryan J.
Published in Neuron (Cambridge, Mass.) (21.10.2015)
Published in Neuron (Cambridge, Mass.) (21.10.2015)
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Journal Article
Zebrafish models of idiopathic scoliosis link cerebrospinal fluid flow defects to spine curvature
Grimes, D. T., Boswell, C. W., Morante, N. F. C., Henkelman, R. M., Burdine, R. D., Ciruna, B.
Published in Science (American Association for the Advancement of Science) (10.06.2016)
Published in Science (American Association for the Advancement of Science) (10.06.2016)
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Journal Article
Relative Target Affinities of T-Cell-Dependent Bispecific Antibodies Determine Biodistribution in a Solid Tumor Mouse Model
Mandikian, Danielle, Takahashi, Nene, Lo, Amy A, Li, Ji, Eastham-Anderson, Jeffrey, Slaga, Dionysos, Ho, Jason, Hristopoulos, Maria, Clark, Robyn, Totpal, Klara, Lin, Kedan, Joseph, Sean B, Dennis, Mark S, Prabhu, Saileta, Junttila, Teemu T, Boswell, C Andrew
Published in Molecular cancer therapeutics (01.04.2018)
Published in Molecular cancer therapeutics (01.04.2018)
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Journal Article
Transferrin receptor (TfR) trafficking determines brain uptake of TfR antibody affinity variants
Bien-Ly, Nga, Yu, Y Joy, Bumbaca, Daniela, Elstrott, Justin, Boswell, C Andrew, Zhang, Yin, Luk, Wilman, Lu, Yanmei, Dennis, Mark S, Weimer, Robby M, Chung, Inhee, Watts, Ryan J
Published in The Journal of experimental medicine (10.02.2014)
Published in The Journal of experimental medicine (10.02.2014)
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Journal Article
Effects of Charge on Antibody Tissue Distribution and Pharmacokinetics
Boswell, C. Andrew, Tesar, Devin B., Mukhyala, Kiran, Theil, Frank-Peter, Fielder, Paul J., Khawli, Leslie A.
Published in Bioconjugate chemistry (15.12.2010)
Published in Bioconjugate chemistry (15.12.2010)
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Journal Article
Preclinical pharmacokinetics, pharmacodynamics, tissue distribution, and tumor penetration of anti-PD-L1 monoclonal antibody, an immune checkpoint inhibitor
Deng, Rong, Bumbaca, Daniela, Pastuskovas, Cinthia V, Boswell, C Andrew, West, David, Cowan, Kyra J, Chiu, Henry, McBride, Jacqueline, Johnson, Clarissa, Xin, Yan, Koeppen, Hartmut, Leabman, Maya, Iyer, Suhasini
Published in mAbs (02.04.2016)
Published in mAbs (02.04.2016)
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Journal Article
Anti-LYPD1/CD3 T-Cell-Dependent Bispecific Antibody for the Treatment of Ovarian Cancer
Lo, Amy A, Johnston, Jennifer, Li, Ji, Mandikian, Danielle, Hristopoulos, Maria, Clark, Robyn, Nickles, Dorothee, Liang, Wei-Ching, Hötzel, Kathy, Dunlap, Debra, Pham, Thinh, Cai, Hao, Ovacik, Meric, Bravo-Perez, Daniel, Mai, Elaine, Slaga, Dionysos, Ellerman, Diego, Ziai, James, Totpal, Klara, Lee, Genee, Boswell, C Andrew, Payandeh, Jian, Wu, Yan, Junttila, Teemu T
Published in Molecular cancer therapeutics (01.04.2021)
Published in Molecular cancer therapeutics (01.04.2021)
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Journal Article
Physiochemical and Biochemical Factors Influencing the Pharmacokinetics of Antibody Therapeutics
Bumbaca, Daniela, Boswell, C. Andrew, Fielder, Paul J., Khawli, Leslie A.
Published in The AAPS journal (01.09.2012)
Published in The AAPS journal (01.09.2012)
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Journal Article
Impact of Drug Conjugation on Pharmacokinetics and Tissue Distribution of Anti-STEAP1 Antibody–Drug Conjugates in Rats
Boswell, C. Andrew, Mundo, Eduardo E, Zhang, Crystal, Bumbaca, Daniela, Valle, Nicole R, Kozak, Katherine R, Fourie, Aimee, Chuh, Josefa, Koppada, Neelima, Saad, Ola, Gill, Herman, Shen, Ben-Quan, Rubinfeld, Bonnee, Tibbitts, Jay, Kaur, Surinder, Theil, Frank-Peter, Fielder, Paul J, Khawli, Leslie A, Lin, Kedan
Published in Bioconjugate chemistry (19.10.2011)
Published in Bioconjugate chemistry (19.10.2011)
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Journal Article
Assessment of university policies for service animals and emotional support animals
Lanning, Beth A, Patterson, M S, Henry, S, Graves-Boswell, C T, Summerall, B, Millan, C
Published in Journal of American college health (12.02.2024)
Published in Journal of American college health (12.02.2024)
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Journal Article
Effect of molecular size on interstitial pharmacokinetics and tissue catabolism of antibodies
Rafidi, Hanine, Rajan, Sharmila, Urban, Konnie, Shatz-Binder, Whitney, Hui, Keliana, Ferl, Gregory Z., Kamath, Amrita V., Boswell, C. Andrew
Published in mAbs (31.12.2022)
Published in mAbs (31.12.2022)
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Journal Article
On Demand Bioorthogonal Switching of an Antibody-Conjugated SPECT Probe to a Cytotoxic Payload: from Imaging to Therapy
Adhikari, Pragya, Li, Guangmin, Go, MaryAnn, Mandikian, Danielle, Rafidi, Hanine, Ng, Carl, Anifa, Sagana, Johnson, Kevin, Bao, Linda, Hernandez Barry, Hilda, Rowntree, Rebecca, Agard, Nicholas, Wu, Cong, Chou, Kang-Jye, Zhang, Donglu, Kozak, Katherine R., Pillow, Thomas H., Lewis, Gail D., Yu, Shang-Fan, Boswell, C. Andrew, Sadowsky, Jack D.
Published in Journal of the American Chemical Society (17.07.2024)
Published in Journal of the American Chemical Society (17.07.2024)
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Journal Article
Framework selection can influence pharmacokinetics of a humanized therapeutic antibody through differences in molecule charge
Li, Bing, Tesar, Devin, Boswell, C Andrew, Cahaya, Hendry S, Wong, Anne, Zhang, Jianhuan, Meng, Y Gloria, Eigenbrot, Charles, Pantua, Homer, Diao, Jinyu, Kapadia, Sharookh B, Deng, Rong, Kelley, Robert F
Published in mAbs (03.09.2014)
Published in mAbs (03.09.2014)
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Journal Article
Hyaluronic Acid–Antibody Fragment Bioconjugates for Extended Ocular Pharmacokinetics
Famili, Amin, Crowell, Susan R, Loyet, Kelly M, Mandikian, Danielle, Boswell, C. Andrew, Cain, David, Chan, Joyce, Comps-Agrar, Laetitia, Kamath, Amrita, Rajagopal, Karthikan
Published in Bioconjugate chemistry (20.11.2019)
Published in Bioconjugate chemistry (20.11.2019)
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Journal Article
Comparative in Vivo Stability of Copper-64-Labeled Cross-Bridged and Conventional Tetraazamacrocyclic Complexes
Boswell, C. Andrew, Sun, Xiankai, Niu, Weijun, Weisman, Gary R, Wong, Edward H, Rheingold, Arnold L, Anderson, Carolyn J
Published in Journal of medicinal chemistry (11.03.2004)
Published in Journal of medicinal chemistry (11.03.2004)
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Journal Article
Balancing the Affinity and Pharmacokinetics of Antibodies by Modulating the Size of Charge Patches on Complementarity-Determining Regions
Sun, Yue, Cai, Hao, Hu, Zhilan, Boswell, C. Andrew, Diao, Jinpian, Li, Charlene, Zhang, Liangyi, Shen, Amy, Teske, Christopher A., Zhang, Boyan, Kamath, Amrita V., Jiang, Guoying
Published in Journal of pharmaceutical sciences (01.12.2020)
Published in Journal of pharmaceutical sciences (01.12.2020)
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Journal Article
Imaging Reveals Importance of Shape and Flexibility for Glomerular Filtration of Biologics
Rafidi, Hanine, Estevez, Alberto, Ferl, Gregory Z, Mandikian, Danielle, Stainton, Shannon, Sermeño, Lauren, Williams, Simon P, Kamath, Amrita V, Koerber, James T, Boswell, C Andrew
Published in Molecular cancer therapeutics (01.10.2021)
Published in Molecular cancer therapeutics (01.10.2021)
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Journal Article