A Highly Efficient Palladium/Copper Cocatalytic System for Direct Arylation of Heteroarenes: An Unexpected Effect of Cu(Xantphos)I
Huang, Jinkun, Chan, Johann, Chen, Ying, Borths, Christopher J, Baucom, Kyle D, Larsen, Robert D, Faul, Margaret M
Published in Journal of the American Chemical Society (24.03.2010)
Published in Journal of the American Chemical Society (24.03.2010)
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Journal Article
SLC46A3 Is Required to Transport Catabolites of Noncleavable Antibody Maytansine Conjugates from the Lysosome to the Cytoplasm
Hamblett, Kevin J, Jacob, Allison P, Gurgel, Jesse L, Tometsko, Mark E, Rock, Brooke M, Patel, Sonal K, Milburn, Robert R, Siu, Sophia, Ragan, Seamus P, Rock, Dan A, Borths, Christopher J, O'Neill, Jason W, Chang, Wesley S, Weidner, Margaret F, Bio, Matthew M, Quon, Kim C, Fanslow, William C
Published in Cancer research (Chicago, Ill.) (15.12.2015)
Published in Cancer research (Chicago, Ill.) (15.12.2015)
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Journal Article
Nitrosamine Reactivity: A Survey of Reactions and Purge Processes
Borths, Christopher J, Burns, Michael, Curran, Timothy, Ide, Nathan D
Published in Organic process research & development (20.08.2021)
Published in Organic process research & development (20.08.2021)
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Journal Article
Selection of a Suitable Physical Form and Development of a Crystallization Process for a PDE10A Inhibitor Exhibiting Enantiotropic Polymorphism
Kiang, Y.-H, Bercot, Eric A, Wu, Qiong, Liu, Jodi, Milburn, Robert R, Cohen, Dawn E, Borths, Christopher J, Saw, Robert E, Staples, Richard J, Davis, Carl, Thiel, Oliver R
Published in Organic process research & development (18.12.2015)
Published in Organic process research & development (18.12.2015)
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Journal Article
Control of Mutagenic Impurities: Survey of Pharmaceutical Company Practices and a Proposed Framework for Industry Alignment
Borths, Christopher J, Argentine, Mark D, Donaubauer, John, Elliott, Eric L, Evans, Jared, Kramer, Timothy Talbot, Lee, Heewon, Parsons, Rodney, Roberts, Jeffrey C, Sluggett, Gregory W, Teasdale, Andrew, Urquhart, Michael, Wang, Ke, Zhuang, Ping
Published in Organic process research & development (16.04.2021)
Published in Organic process research & development (16.04.2021)
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Journal Article
Telescoped Process to Manufacture 6,6,6-Trifluorofucose via Diastereoselective Transfer Hydrogenation: Scalable Access to an Inhibitor of Fucosylation Utilized in Monoclonal Antibody Production
Achmatowicz, Michal M, Allen, John G, Bio, Matthew M, Bartberger, Michael D, Borths, Christopher J, Colyer, John T, Crockett, Richard D, Hwang, Tsang-Lin, Koek, Jan. N, Osgood, Stephen A, Roberts, Scott W, Swietlow, Aleksander, Thiel, Oliver R, Caille, Seb
Published in Journal of organic chemistry (03.06.2016)
Published in Journal of organic chemistry (03.06.2016)
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Journal Article
Development of a Scalable Synthesis of a GPR40 Receptor Agonist
Walker, Shawn D, Borths, Christopher J, DiVirgilio, Evan, Huang, Liang, Liu, Pingli, Morrison, Henry, Sugi, Kiyoshi, Tanaka, Masahide, Woo, Jacqueline C. S, Faul, Margaret M
Published in Organic process research & development (20.05.2011)
Published in Organic process research & development (20.05.2011)
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Journal Article
Practical Asymmetric Conjugate Alkynylation of Meldrum’s Acid-Derived Acceptors: Access to Chiral β-Alkynyl Acids
Cui, Sheng, Walker, Shawn D, Woo, Jacqueline C. S, Borths, Christopher J, Mukherjee, Herschel, Chen, Maosheng J, Faul, Margaret M
Published in Journal of the American Chemical Society (20.01.2010)
Published in Journal of the American Chemical Society (20.01.2010)
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Journal Article
Highly Selective Rhodium-Catalyzed Conjugate Addition Reactions of 4-Oxobutenamides
Zigterman, Jamie L, Woo, Jacqueline C. S, Walker, Shawn D, Tedrow, Jason S, Borths, Christopher J, Bunel, Emilio E, Faul, Margaret M
Published in Journal of organic chemistry (09.11.2007)
Published in Journal of organic chemistry (09.11.2007)
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Journal Article
Nitrosamine Risk Assessments in Oligonucleotides
Borths, Christopher J., Burr, Tracey, Figuccia, Aude, Ford, J. Gair, Guan, Bing, Jones, Michael T., Klingeleers, Didier, Lochner, Susanne, Rodriguez, Andrew A., Wetter, Christian
Published in Organic process research & development (20.10.2023)
Published in Organic process research & development (20.10.2023)
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Journal Article
Development of a Commercial Manufacturing Process for Sotorasib, a First-in-Class KRASG12C Inhibitor
Zhang, Liang, Griffin, Daniel J., Beaver, Matthew G., Blue, Laura E., Borths, Christopher J., Brown, Derek B., Caille, Seb, Chen, Ying, Cherney, Alan H., Cochran, Brian M., Colyer, John T., Corbett, Michael T., Correll, Tiffany L., Crockett, Richard D., Dai, Xi-Jie, Dornan, Peter K., Farrell, Robert P., Hedley, Simon J., Hsieh, Hsiao-Wu, Huang, Liang, Huggins, Seth, Liu, Min, Lovette, Michael A., Quasdorf, Kyle, Reifman, Jonathan, Robinson, Jo Anna, Sangodkar, Rahul P., Sharma, Sonika, Kumar, Srividya Sharvan, Smith, Austin G., St-Pierre, Gabrielle, Tedrow, Jason S., Thiel, Oliver R., Truong, Jonathan V., Walker, Shawn D., Wei, Carolyn S., Wilsily, Ashraf, Xie, Yong, Yang, Ning, Parsons, Andrew T.
Published in Organic process research & development (18.11.2022)
Published in Organic process research & development (18.11.2022)
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Journal Article
Development of a Commercial Manufacturing Process for Sotorasib, a First-in-Class KRAS G12C Inhibitor
Zhang, Liang, Griffin, Daniel J., Beaver, Matthew G., Blue, Laura E., Borths, Christopher J., Brown, Derek B., Caille, Seb, Chen, Ying, Cherney, Alan H., Cochran, Brian M., Colyer, John T., Corbett, Michael T., Correll, Tiffany L., Crockett, Richard D., Dai, Xi-Jie, Dornan, Peter K., Farrell, Robert P., Hedley, Simon J., Hsieh, Hsiao-Wu, Huang, Liang, Huggins, Seth, Liu, Min, Lovette, Michael A., Quasdorf, Kyle, Powazinik, William, Reifman, Jonathan, Robinson, Jo Anna, Sangodkar, Rahul P., Sharma, Sonika, Kumar, Srividya Sharvan, Smith, Austin G., St-Pierre, Gabrielle, Tedrow, Jason S., Thiel, Oliver R., Truong, Jonathan V., Walker, Shawn D., Wei, Carolyn S., Wilsily, Ashraf, Xie, Yong, Yang, Ning, Parsons, Andrew T.
Published in Organic process research & development (18.11.2022)
Published in Organic process research & development (18.11.2022)
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Journal Article
Synthesis of O-Ethyl Thioformate: A Useful Reagent for the Thioformylation of Amines
Borths, Christopher J., Chan, Johann, Burke, Brenda J., Larsen, Robert D.
Published in Synlett (01.12.2009)
Published in Synlett (01.12.2009)
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Journal Article
Salts of obicetrapib and processes for their manufacture and intermediates thereof
Rötheli, Andreas René, Kishida, Muneki, Borths, Christopher J, Cui, Sheng
Year of Publication 11.06.2024
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Year of Publication 11.06.2024
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