Nivolumab plus ipilimumab as first-line treatment for advanced non-small-cell lung cancer (CheckMate 012): results of an open-label, phase 1, multicohort study
Hellmann, Matthew D, Dr, Rizvi, Naiyer A, Prof, Goldman, Jonathan W, MD, Gettinger, Scott N, MD, Borghaei, Hossein, DO, Brahmer, Julie R, MD, Ready, Neal E, Prof, Gerber, David E, MD, Chow, Laura Q, MD, Juergens, Rosalyn A, MD, Shepherd, Frances A, Prof, Laurie, Scott A, MD, Geese, William J, PhD, Agrawal, Shruti, PhD, Young, Tina C, MS, Li, Xuemei, MD, Antonia, Scott J, Prof
Published in The lancet oncology (01.01.2017)
Published in The lancet oncology (01.01.2017)
Get full text
Journal Article
Alectinib in ALK -positive, crizotinib-resistant, non-small-cell lung cancer: a single-group, multicentre, phase 2 trial
Shaw, Alice T, Dr, Gandhi, Leena, MD, Gadgeel, Shirish, Prof, Riely, Gregory J, MD, Cetnar, Jeremy, MD, West, Howard, MD, Camidge, D Ross, MD, Socinski, Mark A, Prof, Chiappori, Alberto, MD, Mekhail, Tarek, MD, Chao, Bo H, MD, Borghaei, Hossein, DO, Gold, Kathryn A, MD, Zeaiter, Ali, MD, Bordogna, Walter, PhD, Balas, Bogdana, MD, Puig, Oscar, PhD, Henschel, Volkmar, PhD, Ou, Sai-Hong Ignatius, Prof
Published in The lancet oncology (01.02.2016)
Published in The lancet oncology (01.02.2016)
Get full text
Journal Article
Nivolumab plus Ipilimumab in Advanced Non–Small-Cell Lung Cancer
Hellmann, Matthew D, Paz-Ares, Luis, Bernabe Caro, Reyes, Zurawski, Bogdan, Kim, Sang-We, Carcereny Costa, Enric, Park, Keunchil, Alexandru, Aurelia, Lupinacci, Lorena, de la Mora Jimenez, Emmanuel, Sakai, Hiroshi, Albert, Istvan, Vergnenegre, Alain, Peters, Solange, Syrigos, Konstantinos, Barlesi, Fabrice, Reck, Martin, Borghaei, Hossein, Brahmer, Julie R, O’Byrne, Kenneth J, Geese, William J, Bhagavatheeswaran, Prabhu, Rabindran, Sridhar K, Kasinathan, Ravi S, Nathan, Faith E, Ramalingam, Suresh S
Published in The New England journal of medicine (21.11.2019)
Published in The New England journal of medicine (21.11.2019)
Get full text
Journal Article
The BiTE (bispecific T‐cell engager) platform: Development and future potential of a targeted immuno‐oncology therapy across tumor types
Einsele, Hermann, Borghaei, Hossein, Orlowski, Robert Z., Subklewe, Marion, Roboz, Gail J., Zugmaier, Gerhard, Kufer, Peter, Iskander, Karim, Kantarjian, Hagop M.
Published in Cancer (15.07.2020)
Published in Cancer (15.07.2020)
Get full text
Journal Article
First-Line Nivolumab Plus Ipilimumab in Advanced Non-Small-Cell Lung Cancer (CheckMate 568): Outcomes by Programmed Death Ligand 1 and Tumor Mutational Burden as Biomarkers
Ready, Neal, Hellmann, Matthew D, Awad, Mark M, Otterson, Gregory A, Gutierrez, Martin, Gainor, Justin F, Borghaei, Hossein, Jolivet, Jacques, Horn, Leora, Mates, Mihaela, Brahmer, Julie, Rabinowitz, Ian, Reddy, Pavan S, Chesney, Jason, Orcutt, James, Spigel, David R, Reck, Martin, O'Byrne, Kenneth John, Paz-Ares, Luis, Hu, Wenhua, Zerba, Kim, Li, Xuemei, Lestini, Brian, Geese, William J, Szustakowski, Joseph D, Green, George, Chang, Han, Ramalingam, Suresh S
Published in Journal of clinical oncology (20.04.2019)
Published in Journal of clinical oncology (20.04.2019)
Get full text
Journal Article
Nivolumab Monotherapy for First-Line Treatment of Advanced Non-Small-Cell Lung Cancer
Gettinger, Scott, Rizvi, Naiyer A, Chow, Laura Q, Borghaei, Hossein, Brahmer, Julie, Ready, Neal, Gerber, David E, Shepherd, Frances A, Antonia, Scott, Goldman, Jonathan W, Juergens, Rosalyn A, Laurie, Scott A, Nathan, Faith E, Shen, Yun, Harbison, Christopher T, Hellmann, Matthew D
Published in Journal of clinical oncology (01.09.2016)
Published in Journal of clinical oncology (01.09.2016)
Get full text
Journal Article
First-Line Nivolumab in Stage IV or Recurrent Non–Small-Cell Lung Cancer
Carbone, David P, Reck, Martin, Paz-Ares, Luis, Creelan, Benjamin, Horn, Leora, Steins, Martin, Felip, Enriqueta, van den Heuvel, Michel M, Ciuleanu, Tudor-Eliade, Badin, Firas, Ready, Neal, Hiltermann, T. Jeroen N, Nair, Suresh, Juergens, Rosalyn, Peters, Solange, Minenza, Elisa, Wrangle, John M, Rodriguez-Abreu, Delvys, Borghaei, Hossein, Blumenschein, George R, Villaruz, Liza C, Havel, Libor, Krejci, Jana, Corral Jaime, Jesus, Chang, Han, Geese, William J, Bhagavatheeswaran, Prabhu, Chen, Allen C, Socinski, Mark A
Published in The New England journal of medicine (22.06.2017)
Published in The New England journal of medicine (22.06.2017)
Get full text
Journal Article
Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer
Borghaei, Hossein, Paz-Ares, Luis, Horn, Leora, Spigel, David R, Steins, Martin, Ready, Neal E, Chow, Laura Q, Vokes, Everett E, Felip, Enriqueta, Holgado, Esther, Barlesi, Fabrice, Kohlhäufl, Martin, Arrieta, Oscar, Burgio, Marco Angelo, Fayette, Jérôme, Lena, Hervé, Poddubskaya, Elena, Gerber, David E, Gettinger, Scott N, Rudin, Charles M, Rizvi, Naiyer, Crinò, Lucio, Blumenschein, George R, Antonia, Scott J, Dorange, Cécile, Harbison, Christopher T, Graf Finckenstein, Friedrich, Brahmer, Julie R
Published in The New England journal of medicine (22.10.2015)
Published in The New England journal of medicine (22.10.2015)
Get full text
Journal Article
Carboplatin and pemetrexed with or without pembrolizumab for advanced, non-squamous non-small-cell lung cancer: a randomised, phase 2 cohort of the open-label KEYNOTE-021 study
Langer, Corey J, Dr Prof, Gadgeel, Shirish M, Prof, Borghaei, Hossein, DO, Papadimitrakopoulou, Vassiliki A, Prof, Patnaik, Amita, MD, Powell, Steven F, MD, Gentzler, Ryan D, MD, Martins, Renato G, Prof, Stevenson, James P, MD, Jalal, Shadia I, MBBS, Panwalkar, Amit, MD, Yang, James Chih-Hsin, Prof, Gubens, Matthew, MD, Sequist, Lecia V, MD, Awad, Mark M, MD, Fiore, Joseph, PharmD, Ge, Yang, PhD, Raftopoulos, Harry, MD, Gandhi, Leena, Prof
Published in The lancet oncology (01.11.2016)
Published in The lancet oncology (01.11.2016)
Get full text
Journal Article
Existing and Emerging Biomarkers for Immune Checkpoint Immunotherapy in Solid Tumors
Arora, Sanjeevani, Velichinskii, Rodion, Lesh, Randy W., Ali, Usman, Kubiak, Michal, Bansal, Pranshu, Borghaei, Hossein, Edelman, Martin J., Boumber, Yanis
Published in Advances in therapy (01.10.2019)
Published in Advances in therapy (01.10.2019)
Get full text
Journal Article
Characterization of KRAS Mutation Subtypes in Non-small Cell Lung Cancer
Judd, Julia, Abdel Karim, Nagla, Khan, Hina, Naqash, Abdul Rafeh, Baca, Yasmine, Xiu, Joanne, VanderWalde, Ari M, Mamdani, Hirva, Raez, Luis E, Nagasaka, Misako, Pai, Sachin Gopalkrishna, Socinski, Mark A, Nieva, Jorge J, Kim, Chul, Wozniak, Antoinette J, Ikpeazu, Chukwuemeka, de Lima Lopes, Jr, Gilberto, Spira, Alexander I, Korn, W Michael, Kim, Edward S, Liu, Stephen V, Borghaei, Hossein
Published in Molecular cancer therapeutics (01.12.2021)
Published in Molecular cancer therapeutics (01.12.2021)
Get full text
Journal Article
Durvalumab with platinum-pemetrexed for unresectable pleural mesothelioma: survival, genomic and immunologic analyses from the phase 2 PrE0505 trial
Forde, Patrick M., Anagnostou, Valsamo, Sun, Zhuoxin, Dahlberg, Suzanne E., Kindler, Hedy L., Niknafs, Noushin, Purcell, Thomas, Santana-Davila, Rafael, Dudek, Arkadiusz Z., Borghaei, Hossein, Lanis, Mara, Belcaid, Zineb, Smith, Kellie N., Balan, Archana, White, James R., Cherry, Christopher, Ashok Sivakumar, I. K., Shao, Xiaoshan M., Chan, Hok Yee, Singh, Dipika, Thapa, Sampriti, Illei, Peter B., Pardoll, Drew M., Karchin, Rachel, Velculescu, Victor E., Brahmer, Julie R., Ramalingam, Suresh S.
Published in Nature medicine (01.11.2021)
Published in Nature medicine (01.11.2021)
Get full text
Journal Article
Pembrolizumab and platinum-based chemotherapy as first-line therapy for advanced non–small-cell lung cancer: Phase 1 cohorts from the KEYNOTE-021 study
Gadgeel, Shirish M., Stevenson, James P., Langer, Corey J., Gandhi, Leena, Borghaei, Hossein, Patnaik, Amita, Villaruz, Liza C., Gubens, Matthew, Hauke, Ralph, Yang, James Chih-Hsin, Sequist, Lecia V., Bachman, Robert, Saraf, Sanatan, Raftopoulos, Harry, Papadimitrakopoulou, Vassiliki
Published in Lung cancer (Amsterdam, Netherlands) (01.11.2018)
Published in Lung cancer (Amsterdam, Netherlands) (01.11.2018)
Get full text
Journal Article
Siltuximab, a Novel Anti–Interleukin-6 Monoclonal Antibody, for Castleman's Disease
VAN RHEE, Frits, FAYAD, Luis, XIANG QIN, HERRING, Jennifer, CASPER, Corey, KURZROCK, Razelle, VOORHEES, Peter, FURMAN, Richard, LONIAL, Sagar, BORGHAEI, Hossein, SOKOL, Lubomir, CRAWFORD, Julie, CORNFELD, Mark, MING QI
Published in Journal of clinical oncology (10.08.2010)
Published in Journal of clinical oncology (10.08.2010)
Get full text
Journal Article
Immune Checkpoint Inhibitor Therapy: What Line of Therapy and How to Choose?
Ramamurthy, Chethan, Godwin, James L., Borghaei, Hossein
Published in Current treatment options in oncology (01.06.2017)
Published in Current treatment options in oncology (01.06.2017)
Get full text
Journal Article
Circulating tumor cell and cell-free RNA capture and expression analysis identify platelet-associated genes in metastatic lung cancer
Beck, Tim N, Boumber, Yanis A, Aggarwal, Charu, Pei, Jianming, Thrash-Bingham, Catherine, Fittipaldi, Patricia, Vlasenkova, Ramillya, Rao, Chandra, Borghaei, Hossein, Cristofanilli, Massimo, Mehra, Ranee, Serebriiskii, Ilya, Alpaugh, R Katherine
Published in BMC cancer (19.06.2019)
Published in BMC cancer (19.06.2019)
Get full text
Journal Article
A phase 1 study of nivolumab in combination with interferon-gamma for patients with advanced solid tumors
Zibelman, Matthew, MacFarlane, Alexander W., Costello, Kimberly, McGowan, Thomas, O’Neill, John, Kokate, Rutika, Borghaei, Hossein, Denlinger, Crystal S., Dotan, Efrat, Geynisman, Daniel M., Jain, Angela, Martin, Lainie, Obeid, Elias, Devarajan, Karthik, Ruth, Karen, Alpaugh, R. Katherine, Dulaimi, Essel Al-Saleem, Cukierman, Edna, Einarson, Margret, Campbell, Kerry S., Plimack, Elizabeth R.
Published in Nature communications (27.07.2023)
Published in Nature communications (27.07.2023)
Get full text
Journal Article
Validation of a Molecular Diagnostic Test for Circulating Tumor DNA by Next-Gen Sequencing
Fernandez, Sandra V., Tan, Yin Fei, Rao, Shilpa, Fittipaldi, Patricia, Sheriff, Fathima, Borghaei, Hossein, Dotan, Efrat, Winn, Jennifer S., Edelman, Martin J., Treat, Joseph, Judd, Julia, Alpaugh, R. Katherine, Wang, Y. Lynn, Yu, Jian Q., Wasik, Mariusz, Baldwin, Don A.
Published in International journal of molecular sciences (01.11.2023)
Published in International journal of molecular sciences (01.11.2023)
Get full text
Journal Article
Musashi-2 (MSI2) regulates epidermal growth factor receptor (EGFR) expression and response to EGFR inhibitors in EGFR-mutated non-small cell lung cancer (NSCLC)
Makhov, Petr, Bychkov, Igor, Faezov, Bulat, Deneka, Alexander, Kudinov, Alexander, Nicolas, Emmanuelle, Brebion, Rohan, Avril, Eleanor, Cai, Kathy Q., Kharin, Leonid V., Voloshin, Mark, Frantsiyants, Elena, Karnaukhov, Nikolay, Kit, Oleg I., Topchu, Iuliia, Fazliyeva, Rushaniya, Nikonova, Anna S., Serebriiskii, Ilya G., Borghaei, Hossein, Edelman, Martin, Dulaimi, Essel, Golemis, Erica A., Boumber, Yanis
Published in Oncogenesis (New York, NY) (15.03.2021)
Published in Oncogenesis (New York, NY) (15.03.2021)
Get full text
Journal Article
The Effects of HER2 Alterations in EGFR Mutant Non-small Cell Lung Cancer
Nagasaka, Misako, Singh, Vijendra, Baca, Yasmine, Sukari, Ammar, Kim, Chul, Mamdani, Hirva, Spira, Alexander I., Uprety, Dipesh, Bepler, Gerold, Kim, Edward S., Raez, Luis E., Pai, Sachin Gopalkrishna, Ikpeazu, Chukwuemeka, Oberley, Matthew, Feldman, Rebecca, Xiu, Joanne, Korn, W. Michael, Wozniak, Antoinette J., Borghaei, Hossein, Liu, Stephen V.
Published in Clinical lung cancer (01.01.2022)
Published in Clinical lung cancer (01.01.2022)
Get full text
Journal Article