Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia
Giustacchini, Alice, Thongjuea, Supat, Barkas, Nikolaos, Woll, Petter S, Povinelli, Benjamin J, Booth, Christopher A G, Sopp, Paul, Norfo, Ruggiero, Rodriguez-Meira, Alba, Ashley, Neil, Jamieson, Lauren, Vyas, Paresh, Anderson, Kristina, Segerstolpe, Åsa, Qian, Hong, Olsson-Strömberg, Ulla, Mustjoki, Satu, Sandberg, Rickard, Jacobsen, Sten Eirik W, Mead, Adam J
Published in Nature medicine (01.06.2017)
Published in Nature medicine (01.06.2017)
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Journal Article
Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation
Mead, Adam J, Neo, Wen Hao, Barkas, Nikolaos, Matsuoka, Sahoko, Giustacchini, Alice, Facchini, Raffaella, Thongjuea, Supat, Jamieson, Lauren, Booth, Christopher A G, Fordham, Nicholas, Di Genua, Cristina, Atkinson, Deborah, Chowdhury, Onima, Repapi, Emmanouela, Gray, Nicki, Kharazi, Shabnam, Clark, Sally-Ann, Bouriez, Tiphaine, Woll, Petter, Suda, Toshio, Nerlov, Claus, Jacobsen, Sten Eirik W
Published in The Journal of experimental medicine (03.07.2017)
Published in The Journal of experimental medicine (03.07.2017)
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Journal Article
Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors
Neo, Wen Hao, Meng, Yiran, Rodriguez-Meira, Alba, Fadlullah, Muhammad Z. H., Booth, Christopher A. G., Azzoni, Emanuele, Thongjuea, Supat, de Bruijn, Marella F. T. R., Jacobsen, Sten Eirik W., Mead, Adam J., Lacaud, Georges
Published in Nature communications (02.12.2021)
Published in Nature communications (02.12.2021)
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Journal Article
Cell-extrinsic hematopoietic impact of Ezh2 inactivation in fetal liver endothelial cells
Neo, Wen Hao, Booth, Christopher A.G., Azzoni, Emanuele, Chi, Lijun, Delgado-Olguín, Paul, de Bruijn, Marella F.T.R., Jacobsen, Sten Eirik W., Mead, Adam J.
Published in Blood (17.05.2018)
Published in Blood (17.05.2018)
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SponTaneous Respiration using IntraVEnous anaesthesia and Hi-flow nasal oxygen (STRIVE Hi) maintains oxygenation and airway patency during management of the obstructed airway: an observational study
Booth, A.W.G., Vidhani, K, Lee, P.K., Thomsett, C.-M.
Published in British journal of anaesthesia : BJA (01.03.2017)
Published in British journal of anaesthesia : BJA (01.03.2017)
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Journal Article
Ultraviolet radiation shapes dendritic cell leukaemia transformation in the skin
Griffin, Gabriel K., Booth, Christopher A. G., Togami, Katsuhiro, Chung, Sun Sook, Ssozi, Daniel, Verga, Julia A., Bouyssou, Juliette M., Lee, Yoke Seng, Shanmugam, Vignesh, Hornick, Jason L., LeBoeuf, Nicole R., Morgan, Elizabeth A., Bernstein, Bradley E., Hovestadt, Volker, van Galen, Peter, Lane, Andrew A.
Published in Nature (London) (22.06.2023)
Published in Nature (London) (22.06.2023)
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Journal Article
Sex-Biased ZRSR2 Mutations in Myeloid Malignancies Impair Plasmacytoid Dendritic Cell Activation and Apoptosis
Togami, Katsuhiro, Chung, Sun Sook, Madan, Vikas, Booth, Christopher A G, Kenyon, Christopher M, Cabal-Hierro, Lucia, Taylor, Justin, Kim, Sunhee S, Griffin, Gabriel K, Ghandi, Mahmoud, Li, Jia, Li, Yvonne Y, Angelot-Delettre, Fanny, Biichle, Sabeha, Seiler, Michael, Buonamici, Silvia, Lovitch, Scott B, Louissaint, Jr, Abner, Morgan, Elizabeth A, Jardin, Fabrice, Piccaluga, Pier Paolo, Weinstock, David M, Hammerman, Peter S, Yang, Henry, Konopleva, Marina, Pemmaraju, Naveen, Garnache-Ottou, Francine, Abdel-Wahab, Omar, Koeffler, H Phillip, Lane, Andrew A
Published in Cancer discovery (01.02.2022)
Published in Cancer discovery (01.02.2022)
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Journal Article
Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia
Louka, Eleni, Povinelli, Benjamin, Rodriguez-Meira, Alba, Buck, Gemma, Wen, Wei Xiong, Wang, Guanlin, Sousos, Nikolaos, Ashley, Neil, Hamblin, Angela, Booth, Christopher A G, Roy, Anindita, Elliott, Natalina, Iskander, Deena, de la Fuente, Josu, Fordham, Nicholas, O'Byrne, Sorcha, Inglott, Sarah, Norfo, Ruggiero, Salio, Mariolina, Thongjuea, Supat, Rao, Anupama, Roberts, Irene, Mead, Adam J
Published in The Journal of experimental medicine (01.02.2021)
Published in The Journal of experimental medicine (01.02.2021)
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Journal Article
Targetable leukaemia dependency on noncanonical PI3Kγ signalling
Luo, Qingyu, Raulston, Evangeline G., Prado, Miguel A., Wu, Xiaowei, Gritsman, Kira, Whalen, Karley S., Yan, Kezhi, Booth, Christopher A. G., Xu, Ran, van Galen, Peter, Doench, John G., Shimony, Shai, Long, Henry W., Neuberg, Donna S., Paulo, Joao A., Lane, Andrew A.
Published in Nature (London) (06.06.2024)
Published in Nature (London) (06.06.2024)
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Journal Article
Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors
Booth, Christopher A.G., Barkas, Nikolaos, Neo, Wen Hao, Boukarabila, Hanane, Soilleux, Elizabeth J., Giotopoulos, George, Farnoud, Noushin, Giustacchini, Alice, Ashley, Neil, Carrelha, Joana, Jamieson, Lauren, Atkinson, Deborah, Bouriez-Jones, Tiphaine, Prinjha, Rab K., Milne, Thomas A., Teachey, David T., Papaemmanuil, Elli, Huntly, Brian J.P., Jacobsen, Sten Eirik W., Mead, Adam J.
Published in Cancer cell (12.02.2018)
Published in Cancer cell (12.02.2018)
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Journal Article
Characteristics of the ultrafine component of fly ash
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Conference Proceeding
Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation
Di Genua, Cristina, Norfo, Ruggiero, Rodriguez-Meira, Alba, Wen, Wei Xiong, Drissen, Roy, Booth, Christopher A G, Povinelli, Benjamin, Repapi, Emmanouela, Gray, Nicki, Carrelha, Joana, Kettyle, Laura M, Jamieson, Lauren, Neo, Wen Hao, Thongjuea, Supat, Nerlov, Claus, Mead, Adam J
Published in Haematologica (Roma) (01.11.2019)
Published in Haematologica (Roma) (01.11.2019)
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